Storage Of Products Research Articles

Molecular Mechanisms of Rett Syndrome: Emphasizing the Roles of Monoamine, Immunity, and Mitochondrial Dysfunction

Rett syndrome (RTT), which predominantly affects females, arises in most cases from mutations in the Methyl-CpG-binding Protein-2 (MECP2) gene. When MeCP2 is impaired, it disrupts the regulation of numerous genes, causing the production of dysfunctional proteins associated with various multi-systemic issues in RTT. In this review, we explore the current insights into molecular signaling related to monoamines, immune response, and mitochondrial function, and their implications for the pathophysiology of RTT. Research has shown that monoamines—such as dopamine, norepinephrine, epinephrine, serotonin, and histamine—exhibit alterations in RTT, contributing to a range of neurological symptoms. Furthermore, the immune system in RTT individuals demonstrates dysfunction through the abnormal activity of microglia, macrophages, lymphocytes, and non-immune cells, leading to the atypical release of inflammatory mediators and disruptions in the NF-κB signaling pathway. Moreover, mitochondria, essential for energy production and calcium storage, also show dysfunction in this condition. The delicate balance of producing and scavenging reactive oxygen species—termed redox balance—is disrupted in RTT. Targeting these molecular pathways presents a promising avenue for developing effective therapies.

EFFECT OF AFLATOXIN EXPOSURE IN LIVESTOCK AND PUBLIC HEALTH: REVIEW

Aflatoxins are toxic metabolites produced by the fungi Aspergillus parasiticus and Aspergillus flavus, which commonly infest various nutritious foods and animal feed. Given the widespread occurrence of aflatoxins and their significant impact on livestock and public health, understanding the mechanisms of toxicity, routes of exposure and economic implications is crucial. This review aims to investigate the causes and effects of aflatoxin exposure on both human and animal health while proposing strategies for preventing and controlling contamination. Aflatoxin contamination impacts the entire food chain, affecting the production, storage, processing, trade and consumption of both plant and animal products. Its consequences extend to human health, livestock welfare, agricultural productivity, environmental integrity and trade, particularly in regions with inadequate aflatoxin control measures. Aflatoxicosis can result in acute mortality, cancer, immune suppression and other chronic health issues. Effective control measures include pre-harvest interventions, careful management during harvest and post-harvest decontamination. Strategies such as selecting resistant crop varieties, employing biological decontamination using microorganisms, physically removing contaminated materials and chemically inactivating aflatoxins are crucial for prevention. Regulating aflatoxin levels in food and feed is essential for protecting public health and promoting equitable trade, necessitating the establishment and enforcement of maximum allowable limits.

Unlocking the Potential of Remanufacturing Through Machine Learning and Data-Driven Models—A Survey

As a key strategy for achieving a circular economy, remanufacturing involves bringing end-of-use (EoU) products or cores back to a ‘like new’ condition, providing more affordable and sustainable alternatives to new products. Despite the potential for substantial resources and energy savings, the industry faces operational challenges. These challenges arise from uncertainties surrounding core quality and functionality, return times, process variation required to meet product specifications, and the end-of-use (EoU) product values, as well as their new life expectancy after extended use as a ‘market product’. While remanufacturing holds immense promise, its full potential can only be realized through concerted efforts towards resolving the inherent complexities and obstacles that impede its operations. Machine learning (ML) and data-driven models emerge as transformative tools to mitigate numerous challenges encountered by manufacturing industry. Recently, the integration of cutting-edge technologies, such as sensor-based product data acquisition and storage, data analytics, machine health management, artificial intelligence (AI)-driven scheduling, and human–robot collaboration (HRC), in remanufacturing procedures has received significant attention from remanufacturers and the circular economy community. These advanced computational technologies help remanufacturers to implement flexible operation scheduling, enhance quality control, and streamline workflows for EoU products. This study embarks on a comprehensive review and in-depth analysis of state-of-the-art algorithms across various facets of remanufacturing processes and operations. Additionally, it identifies key challenges to advancing remanufacturing practices through data-driven and ML methods and uncovers research opportunities in synergy with smart manufacturing techniques. The study aims to offer guidelines for stakeholders and to reinforce the industry’s pivotal role in circular economy initiatives.

Multiscale Qualitative–Quantitative Characterization of the Pore Structure in Coal-Bearing Reservoirs of the Yan’an Formation in the Longdong Area, Ordos Basin

Accurate characterization of coal reservoir micro- and nanopores is crucial in evaluating coalbed methane storage and gas production capacity. In this work, 12 coal-bearing rock samples from the Jurassic Yan’an Formation, Longdong area, Ordos Basin were taken as research objects, and micro- and nanopore structures were characterized via scanning electron microscopy, high-pressure mercury pressure, low-temperature N2 adsorption and low-pressure CO2 adsorption experiments. The main factors controlling coal pore structure development and the influence of pore development on the gas content were studied by combining the reflectivity of specular samples from the research area, the pore microscopic composition and the pore gas content determined through industrial analyses and isothermal absorption experiments. The results show that the coal strata of the Yan’an coal mine are a very important gas source, and that the coal strata of the Yan’an Formation in the study area exhibit remarkable organic and clay mineral pore development accompanied by clear microfractures and clay mineral interlayer joints, which together optimize the coal gas storage conditions and form efficient microseepage pathways for gas. Coalstone, carbonaceous mudstone and mudstone show differential distributions in pore volume and specific surface area. The general trend is that coal rock is the best, carbonaceous mudstone is the second best, and mudstone is the weakest. The coal samples’ microporous properties are positively correlated with the coal sample composition for the specular group, whereas there is no clear correlation for the inert group. An increase in the moisture content of the air-dried matrix promotes adsorption pore development, leading to increases in the microporous volume and specific surface area. CH4 adsorption in coal rock increases with increasing pressure, and the average maximum adsorption is approximately 8.13 m3/t. The limit of the amount of methane adsorbed by the coal samples, VL, is positively correlated with the pore volume and specific surface area, indicating that the larger the pore volume is, the greater the amount of gas that can be adsorbed by the coal samples, and the larger the specific surface area is, the greater the amount of methane that can be adsorbed by the coal samples. The PL value, pore volume and specific surface area are not correlated, indicating that there is no direct mathematical relationship between them.

A community-based analysis of security practices regarding over-the-counter skincare products in nationwide retail drug stores.

Access to over-the-counter (OTC) skincare products is critical for managing a wide range of dermatologic conditions, yet recent trends in urban retail stores may jeopardize this accessibility and exacerbate healthcare disparities. However, the emerging trend of securing skincare products behind security glass in urban retail environments poses significant risks to healthcare equity and accessibility. Herein, we aim to quantify the prevalence of skincare products behind security glass in pharmacies within a 25-mile radius of Times Square, New York City. An observational, cross-sectional study was conducted, selecting 50 pharmacies from a total of 389 identified in the target radius. Digital photographs of skincare product aisles were taken, and the percentage of products secured behind glass was calculated for various categories and brands. The study found significant disparities in the availability of skincare products, with significantly higher percentages of products behind security glass in pharmacies located in urban areas compared to suburban regions. Among the four brands analyzed, Olay, L'Oréal, La Roche-Posay, and Vichy, there was no significant difference in the proportion of products behind security glass. Barriers to accessing skincare products, such as physical restrictions, time constraints, stigma, and privacy issues, may hinder individuals from obtaining necessary treatments, leading to potential delays in care and poorer health outcomes. Our study underscores the urgent need for dermatologists and healthcare policymakers to advocate for alternative security measures that do not compromise product accessibility. Facilitating easier access to OTC skincare products could dramatically improve treatment adherence and patient outcomes, particularly in urban settings where disparities are most pronounced.

A framework for high resolution coupled global electricity & hydrogen models based on integrated assessment model scenarios

Technology-rich Integrated Assessment Models (IAMs) offer the possibility to endogenously resolve hydrogen demand as a function of competition between technologies to meet energy service demands while considering wider interactions with climate and the economy. Such models are typically configured with relatively low spatial and temporal resolution thereby limiting their utility in studying future global hydrogen trade scenarios. This work presents a framework for the soft-linking of IAM scenarios to a higher spatial and temporal resolution global model. This framework provides an “engine” with which to generate future-looking coupled hydrogen & electricity models with the co-optimization of production capacity, storage, and transmission infrastructure that allow the user to vary key technoeconomic input parameters. The modelling framework is applied to an IAM scenario and validated against the parent IAM. The utility of the model when examining electricity & hydrogen commodity trade in future scenarios is then demonstrated.

Effect of ozone gas on Attagenus fasciatus (Thunberg) (Coleoptera: Dermestidae) and Gibbium psylloides (Czempinski) (Coleoptera: Ptinidae) as stored silkworm product pests

The insecticidal potential of ozone gas was tested against two insect pests of stored silkworm products, Attagenus fasciatus (Thunberg) (Coleoptera: Dermestidae) and Gibbium psylloides (Czempinski) (Coleoptera: Ptinidae). Ozone was tested at three concentrations, 500, 1000 and 1500 ppmv for three exposure times, 1, 2 and 3 h. The adult mortality of two insects was counted during 7 days of treatment. Changes in the morphological features of two insect's adults were examined under scanning electron microscope (SEM) and the chemical composition of treated silkworm cocoons with ozone was determined. Adult mortality of A. fasciatus and G. psylloides was improved with the increase in ozone concentration and exposure time. Thus, all tested concentrations caused complete adult mortality of A. fasciatus after 3 and 5 days of treatment at two exposure times (2 and 3 h), respectively. While the two concentrations of ozone (1000 and 1500 ppmv) caused full mortality of G. psylloides adults after 5 days of treatments at exposure time 3 h. Examination with SEM of treated adults showed induction malformations on the dorsal surface as split between elytra and between the thorax and elytra as well as a split the head capsule from the thorax. Additionally, there was a decrease in the density of some microtrichiae of A. fasciatus. While in case of G. psylloides, observed induction shrinking and deformities occurred in the abdominal cuticles and the abdomen was exploded as results treating of ozone gas. Furthermore, the chemical composition analysis of treated silkworm cocoons showed a slight decrease in protein and carbohydrate contents and increasing at the fat, moisture, fiber and ash contents. Our results indicated that the ozone gas seems to be a promising fumigant for the control of A. fasciatus and G. psylloides.

Unveiling the Enigma of Blind Box Impulse Buying Curiosity: The Moderating Role of Price Consciousness

This study explores the causes of curiosity-driven impulse buying in blind boxes using the Stimulus-Organism-Response (S-O-R) model and adaptation level theory. It examines how store environment and product factors contribute to customer curiosity, incorporating price consciousness into the overall framework. Insights from an online survey of 306 Chinese respondents indicate that environmental factors and specific product characteristics positively influence consumer curiosity, while price consciousness has a negative moderate effect. The findings also show that customer curiosity stimulates impulse buying behavior and mediates the relationship between store atmosphere, surprise, and perceived novelty. This study identifies both objective and subjective factors behind blind box impulse buying and offers relevant suggestions for governments and consumers on managing impulse buying.

Hydrogen injection and withdrawal performance in depleted gas reservoirs

Residual gas trapping in porous media is a key indicator of hydrogen storage and recovery performance. The injection scheme of cushion and working gases helps maintain pressure and reduce losses. However, this information is limited in the literature. This work explores core flooding experiments (using electrical resistivity for in-situ saturation monitoring) on Bandera Grey sandstones under reservoir conditions (42 °C, 1400 psi, and 5 wt% NaCl), investigating cushion gas type and injection rate effects on storage and recovery performance. Results indicate that CO2 injection ahead of hydrogen yielded the highest storage capacity with Sgi=0.255, then CH4: Sgi=0.226 and finally, N2: Sgi=0.216. At lower injection rates (0.2–0.6 cc/min), CH4 cushion gas exhibited the highest recovery (42%), whereas at higher injection rates (1.2–10 cc/min), CO2 resulted in the highest, with 33%. These findings emphasize cushion gas's role in enhancing hydrogen storage capacity and production efficiency in depleted gas reservoirs.

Experimental study of microscopic oil production and CO2 storage in low-permeable reservoirs

Experimental study of microscopic oil production and CO2 storage in low-permeable reservoirs

Multi-Objective Model for Residential Energy Management in Context of Individual Self-Consumption

The European Union (EU) strongly urged its member states to take action to establish energy communities. Domestic consumers now have the opportunity to organize themselves to play an active and decisive role in the electricity supply chain and make a solid contribution to an ecological footprint. This work proposes residential energy management, considering renewable resources production (photovoltaic panels) and energy storage systems for individual self-consumption approach and boosting future participation in energy community interactions. A multi-objective optimization model using Biased Random Key Genetic Algorithm (BRKGA) was adapted and implemented to minimize electricity consumption costs and maximize self-consumption usage. An energy storage system with 10kW was considered to optimize electricity management. Two scenarios were proposed, one considering a residential prosumer with a photovoltaic (PV) power installed value of 3.56kWp and the other with 4.20kWp. The results showed a reduction in electricity consumption between 7%-8% and an increase in self-consumption supported by a battery energy storage system of nearly 50%. Data from an actual system were used to obtain realistic scenarios.

COOLING PERFORMANCE POTENTIAL OF TEC1-12710 AND TEC1-12715 SR THERMOELECTRIC MODULES WITH HOT SIDE COOLING OPTIMIZATION METHODS USING SEVERAL TYPES OF HEAT EXCHANGERS

Thermoelectric module is a mature technology that have been used in cooling applications such as special product storage cabins and cooling electronic products. Compared to the conventional technology (vapor compression systems), thermoelectric modules offer many advantages. However, in terms of cooling performance, particularly for large cooling capacities (>100Watt), thermoelectric modules still lag the conventional technology. One method that can be used to improve the cooling performance of thermoelectric modules is cooling the hot side of the module using a heat exchanger. In this study, experiments will be carried out on the TEC1-12710 and TEC1-12715 SR modules which alternately combined with five types of heat exchangers on the hot side of the module, connected by thermal paste. The types of heat exchangers used are Square HE, Round HE, Two-Pipe HE, Four-Pipe HE, and Liquid-Cooler HE. The experiments are carried out with operating voltage variations of 12V, 9V and 6V for each thermoelectric module. The data analysis results found that the best COP value was obtained by the TEC1-12715 SR thermoelectric module with the Round type Heat Exchanger of 0.767 at a voltage of 6V. For the TEC1-12710 thermoelectric module, the highest COP value was also obtained when the module was paired with a Round type Heat Exchanger at a voltage of 6V, with a value of 0.620. Additionally, the highest heat absorption value for both thermoelectric modules was obtained at a voltage of 12V using the Round type heat exchanger, namely 19.61 Watts (TEC1-12710) and 26.98 Watts (TEC1-12715 SR), respectively.

Soil fungi remain active and invest in storage compounds during drought independent of future climate conditions

Microbial growth is central to soil carbon cycling. However, how microbial communities grow under climate change is still largely unexplored. Here we use a unique field experiment simulating future climate conditions (increased atmospheric CO2 and temperature) and drought concomitantly and investigate impacts on soil microbial activity. We trace 2H or 18O applied via water-vapor exchange into membrane (and storage) fatty acids or DNA, respectively, to assess community- and group-level adjustments in soil microbial physiology (replication, storage product synthesis, and carbon use efficiency). We show that, while bacterial growth decreases by half during drought, fungal growth remains stable, demonstrating a remarkable resistance against soil moisture changes. In addition, fungal investment into storage triglycerides increases more than five-fold under drought. Community-level carbon use efficiency (the balance between anabolism and catabolism) is unaffected by drought but decreases in future climate conditions, favoring catabolism. Our results highlight that accounting for different microbial growth strategies can foster our understanding of soil microbial contributions to carbon cycling and feedback on the climate system.

AC energy islands for the optimal integration of offshore wind energy resources: Operation strategies using multi-objective nonlinear programming

The increasing need for integrating offshore wind generation into power systems has highlighted energy islands as a promising solution. Such islands also could incorporate responsive infrastructure for improving grid flexibility such as energy storage and hydrogen production. AC energy islands could be particularly cost–benefit effective for short and medium distances between wind power parks and onshore grids. However, the implementation of AC energy islands presents challenges from the viewpoints of voltage stability, power dispatch and reliable operation. This paper develops optimal operation strategies for AC energy islands including: i) a nonlinear optimal power flow approach for controlling the reactive power compensation systems; ii) a finite horizon mathematical programming approach for the management of BESS and hydrogen production systems; and iii) a multi-objective programming approach for maximizing the active power delivered to the onshore power grid while minimizing the nodal voltage deviations simultaneously. Results show that the single-objective approach for real and reactive power dispatch reduces voltage deviations by around 20 % and line currents by over 70 % in the evaluated test system, compared to the non-optimal scenario. Moreover, the incorporation of energy storage in AC energy island test system increased the capacity for power dispatch over 10 %. Additionally, the multi-objective approach is effective in aligning the nodal voltages with nominal values and maximizing the power delivered to the onshore grid. Results show that with a small 1% reduction in power delivery, the proposed multi-objective approach achieved an approximate 50 % decrease in nodal voltage compared to the single-objective approach.

Youth and Young Adult Access to Flavored Vaping Products Following a Sales Restriction in New York State: A Mixed Methods Approach.

We examined youth and young adult access to flavored vaping products following New York's (NY's) flavored vaping product sales restriction in 2020. In 2021, we conducted an online survey (N = 493) and focus groups (N = 33) with NY youth and young adults who vaped in the past year (ages 15-24). We summarize findings and use logistic regression to assess associations with access to flavored vaping products. Most youth and young adults who vaped in the past year (64%) had obtained flavored vaping products. Among them, 49% purchased in a store, 47% got them from social sources, and 11% bought online. Focus group participants reported restricted products were available on store shelves or behind the counter. Those under age 21 were less likely to buy flavored vaping products in store than those aged 21-24, but age was unrelated to online purchases. Focus group participants reported websites did not require age verification, or they found ways to circumvent it. Most believed buying flavored vaping products was easy (77%) and had gotten easier or stayed the same in the past year (70%). Most NY youth and young adults who vaped in the past year obtained flavored vaping products and found it easy to buy them after the statewide sales restriction, suggesting that implementation has not occurred as intended. Findings also raise questions about retailer compliance and highlight enforcement challenges with online purchases. Continued retailer education and enforcement efforts, including for online sales, may help flavored vaping product sales restrictions achieve intended outcomes.

Ce-modified Cu nanoparticles with N-doped carbon encapsulation for efficient H2 production from aqueous phase reforming of methanol at low temperatures

Aqueous-phase reforming of methanol (APRM) for both hydrogen (H2) production and high pressure storage shows promising potential in mobile/distributed fuel cell stations or vehicles. Currently, achieving efficient H2 production with low CO selectivity (S-CO) at lower temperatures remains a challenge for its application in these fields (rapid start and running in cycles). Herein, the catalyst of Ce-modified Cu nanoparticles with N-doped carbon encapsulation (Cu-CeO2@PVP catalyst) is developed to give excellent H2 production rate at low temperatures ranging from 110 °C to 180 °C, ensuring excellent hydrothermal stability. The H2 production rate of 32.56 μmol·gcat-1·s−1 at 180 °C is 6.1 times to 10.2 times higher than those of commercial catalysts, which demonstrates its superior performance. The combined effect of Cu+/Cu0 and CeO2 promotes the H2 production from CH3OH/H2O. It also suppresses the CO formation by enhancing the H2O dissociation, CO conversion and HCOOH decomposition in APRM. The stable high purified H2 flow from the integrated slurry bed APRM device can start immediately the fuel cell vehicle without any delay.

Progress of ABA function in endosperm cellularization and storage product accumulation.

Seed development is a complex process and co-regulated by genetic and environmental factors, which significantly affects the seed vigor, yield and quality of crops, especially in cereal crops. Abscisic acid (ABA) regulates various biological processes in seed development, including endosperm and embryo development, accumulation of storage materials, achievement of desiccation tolerance and dormancy. Compared to the functional investigation of ABA in germination and stress response, the role of ABA in early seed development and storage product accumulation has not been collectively elucidated. Here, ABA origin in seed was concluded: both maternal source and de novo synthesis of ABA in seed play an important role in seed development. This review also provided an overview of the current knowledge on ABA in early seed development, mainly in endosperm cellularization. ABA promotes endosperm cellularization in Arabidopsis, but this notion has not been spread into cereal crops. Besides, the increasing importance of ABA in seed reserve accumulation was also emphatically described. In the last section, the key problems and challenges (e.g., where dose ABA come from at each stage of seed development? whether same regulators in response to ABA in Arabidopsis apply equally to cereal crops) were addressed.

Comparative Study of Different Medicinal Plants Extracts as Repellency and Toxicity against Tribolium castaneum Herbst

Many plant species possess significant potential for use as medicinal agents, offering not only therapeutic benefits for humans and animals but also acting as natural insect repellents for the protection of stored grains. This study explores the repellency and toxicity of specific medicinal plants, particularly those that exhibit resistance to insect infestation. The investigation focused on the efficacy of the leaves of several selected plants against Tribolium castaneum, a common pest affecting stored grain products. The toxicity was evaluated by recording insect mortality at different intervals (12, 24, 48, and 72 hours) after exposure to plant extracts. Results showed that plant materials had varying effects depending on the species used, the type of insect, and the duration of exposure. Additionally, the repellent properties of the plant extracts were assessed, with the test leaves demonstrating repellency rates of 76% to 78% against Tribolium castaneum, significantly higher compared to the control group, which lacked any plant material. This study highlights the potential application of medicinal plants in pest management as a natural, eco-friendly alternative to chemical pesticides for grain protection.

Edible Coatings for Fish Preservation: Literature Data on Storage Temperature, Product Requirements, Antioxidant Activity, and Coating Performance-A Review.

Fresh fish is among the most nutritive foodstuffs, but it is also the most perishable one. Therefore, huge efforts have been made to find the most suitable tools to deliver fish of the highest quality to exigent consumers. Scientific studies help the industry to exploit the newest findings to scale up emerging industrial technologies. In this review article, the focus is on the latest scientific findings on edible films used for fish coatings and storage. Since today's packaging processing and economy are governed by sustainability, naturality underpins packaging science. The synthesis of edible coatings, their components, processing advantages, and disadvantages are outlined with respect to the preservation requirements for sensitive fish. The requirements of coating properties are underlined for specific scenarios distinguishing cold and freezing conditions. This review raises the importance of antioxidants and their role in fish storage and preservation. A summary of their impact on physical, chemical, microbiological, and sensory alterations upon application in real fish is given. Studies on their influence on product stability, including pro-oxidant activity and the prevention of the autolysis of fish muscle, are given. Examples of lipid oxidation and its inhibition by the antioxidants embedded in edible coatings are given together with the relationship to the development of off-odors and other unwanted impacts. This review selects the most significant and valuable work performed in the past decade in the field of edible coatings whose development is on the global rise and adheres to food waste and sustainable development goals 2 (zero hunger), 3 (good health and well-being), and 12 (responsible consumption and production).

CONCEPTUAL FOUNDATIONS OF MARKETING ORGANIZATION AND LOGISTICS MANAGEMENT IN AGRIBUSINESS

Objective: This study aims to explore the impact of marketing and logistics systems on the efficiency of agricultural product production, storage, and sales, focusing on the challenges faced by agricultural producers in Uzbekistan. Methods: The research employs a systematic analysis of the agricultural supply chain, evaluating the role of marketing and logistics in managing the flow of goods, determining production volumes, and assessing market capacities. Data is gathered through literature review, case studies, and qualitative analysis of existing agricultural practices. Results: The findings highlight significant inefficiencies in the current agricultural logistics system, where the lack of proper marketing strategies and logistics infrastructure leads to high production and transportation costs, imbalances in consumer markets, and low competitiveness. The study identifies key areas where improvements in the marketing-logistics framework can reduce costs by 10-15%, enhance production planning, and better align supply with consumer demand. Novelty: This research introduces a comprehensive approach to integrating marketing and logistics systems in agricultural production, emphasizing the importance of strategic coordination between resource suppliers, producers, and market demands. It provides insights into developing a more efficient, market-responsive agricultural sector in Uzbekistan