A greenhouse experiment was conducted at Jimma University College of Agriculture and Veterinary Medicine (JUCAVM) during the season of 2016/2017. The rapid population increase and land scarcity calls for an alternative of crop production for sustenance of the human race. Productivity of Hot pepper is limited due to Lack of improved, good quality and well adapted varieties, nutrient depletion (poor soil fertility) and inappropriate fertilizer utilization. Treatments consisted of four hot pepper varieties (Mareko Fana, Melka Shote, Melka Awaze and Local Variety) and five potting media mixture (Topsoil, FYM + Top soil + Sand, Compost + Top soil + Sand, Compost + FYM + top soil and Top soil +Sand). The result of the study showed in most cases all the studied growth parameters were significantly higher in pot treated by compost +FYM + top soil and control treatment was significantly reduced the all the plant growth parameter. Accordingly, the tallest and lowest plant height was recorded from variety Melka shote and Local variety respectively. Also the study revealed that higher significant (p<0.05) interactions between potting media and varieties on days to 50% flowering, days to 50% fruit set, days to 50% fruit maturity, days to first harvest, mean number of flowers per plant, mean number of primary branches, number of fruit per plant, number of seed per fruit, pericarp thickness, fruit length and fruit diameter. As a result, the earliest variety to attain days to 50% flowering, days to 50% fruit set and days to 50% fruit maturity and also days to first harvest was recorded from Mareko Fana in PM4. The highest number of fruits per plant was from Melka Shote with mixture of PM4, while Mareko Fana was the highest fruit weight per hak and number of seed per fruit in the potting media of PM4. Similarly, the longest, widest, thickest fruit size and highest cost benefit ratio was attained from Mareko Fana with in PM4. In addition, Mareko Fana were highly preferred and accepted by consumers and this may be attributed to its high quality, larger fruits size and diameter. As results from the study revealed, PM4 could be successfully used to obtain better growth, yield and quality of hot pepper. However, further testing is required in different locations on different potting media.
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