Results are presented on the exclusive production of four-prong final states in photon-photon collisions from the TPC/Two-Gamma detector at the SLAC e+e− storage ring PEP. Measurement of dE/dx and momentum in the time-projection chamber (TPC) provides identification of the final states 2π+2π−, K+K−π+π−, and 2K+2K−. For two quasireal incident photons, both the 2π+2π− and K+K−π+π− cross sections show a steep rise from threshold to a peak value, followed by a decrease at higher mass. Cross sections for the production of the final states ρ0ρ0, ρ0π+π−, and φπ+π− are presented, together with upper limits for φρ0, φφ, and K*0K¯ *0. The ρ0ρ0 contribution dominates the four-pion cross section at low masses, but falls to nearly zero above 2 GeV. Such behavior is inconsistent with expectations from vector dominance but can be accommodated by four-quark resonance models or by t-channel factorization. Angular distributions for the part of the data dominated by ρ0ρ0 final states are consistent with the production of JP=2+ or 0+ resonances but also with isotropic (nonresonant) production. When one of the virtual photons has mass (mγ2=-Q2≠0), the four-pion cross section is still dominated by ρ0ρ0 at low final-state masses Wγγ and by 2π+2π− at higher mass. Further, the dependence of the cross section on Q2 becomes increasingly flat as Wγγ increases.Received 27 February 1987DOI:https://doi.org/10.1103/PhysRevD.37.28©1988 American Physical Society