The purpose of this study is to analyze the importance of criminalization in the use of animal testing in the production of cosmetics in Indonesia as well as the right formulation in the formation of policies on animal testing. The problem is why a criminalization policy is needed against producers who conduct animal testing as a product test in the cosmetics production process and how the formulation of criminalization arrangements against producers who conduct animal testing as a test of cosmetics products in the production process. To be able to answer the formulation of the problem, the research used is normative juridical research with a statutory approach and a comparative approach and conceptual approach. The results show that in conducting animal testing there is the concept of 3R (Replacement, Reduction and Refinement). The 3R concept is an ethic that can be used to realize an experiment by looking for possible alternatives. Because many cosmetic companies are competing in creating new innovations in order to meet the needs of consumers, so that not a few companies carry out the innovation process carried out by related parties in developing their products still often use animals for product trials, which in practice this reaps many cons both from an ethical and scientific perspective. For this reason, criminalization is needed with the existence of legal policies, especially criminal law policies with formulations that regulate starting from the procedure for conducting animal tasting, what animals can be used as animal tasting, and what the procedure is after conducting animal testing, and of course whether it is necessary to submit an application to the competent authority before conducting animal testing, finally that in a legislation also regulates how sanctions / penalties are given to everyone who deliberately violates these laws and regulations.