With the development of deep learning in the field of medical image segmentation, various network segmentation models have been developed. Currently, the most common network models in medical image segmentation can be roughly categorized into pure convolutional networks, Transformer-based networks, and networks combining convolution and Transformer architectures. However, when dealing with complex variations and irregular shapes in medical images, existing networks face issues such as incomplete information extraction, large model parameter sizes, high computational complexity, and long processing times. In contrast, models with lower parameter counts and complexity can efficiently, quickly, and accurately identify lesion areas, significantly reducing diagnosis time and providing valuable time for subsequent treatments. Therefore, this paper proposes a lightweight network named MCI-Net, with only 5.48 M parameters, a computational complexity of 4.41, and a time complexity of just 0.263. By performing linear modeling on sequences, MCI-Net permanently marks effective features and filters out irrelevant information. It efficiently captures local-global information with a small number of channels, reduces the number of parameters, and utilizes attention calculations with exchange value mapping. This achieves model lightweighting and enables thorough interaction of local-global information within the computation, establishing an overall semantic relationship of local-global information. To verify the effectiveness of the MCI-Net network, we conducted comparative experiments with other advanced representative networks on five public datasets: X-ray, Lung, ISIC-2016, ISIC-2018, and capsule endoscopy and gastrointestinal segmentation. We also performed ablation experiments on the first four datasets. The experimental results outperformed the other compared networks, confirming the effectiveness of MCI-Net. This research provides a valuable reference for achieving lightweight, accurate, and high-performance medical image segmentation network models.