Event Abstract Back to Event Altered hemispheric asymmetries of auditory evoked potentials after cochlear implantation Pascale Sandmann1*, T. Eichele2, S. Debener3, 4, M. Buechler5, L. Jancke1, N. Dillier5, Kenneth Hugdahl2, 6 and M. Meyer1 1 University of Zurich, Switzerland 2 University of Bergen, Norway 3 MRC Institute of Hearing Research of Southampton, United Kingdom 4 University of Southampton, United Kingdom 5 University Hospital Zurich, Switzerland 6 Haukeland University Hospital, Norway Hearing can be restored in individuals suffering from severe and profound hearing loss using a cochlear implant (CI). A CI bypasses the outer and middle ear and directly stimulates the (residual) fibres of the auditory nerve. To assess auditory cortex functions, late auditory evoked potentials (AEPs) are widely used in clinical context. However, in CI users electrophysiological measures are of limited utility due to the generation of electrical artefacts in the electroencephalogram (EEG). In order to evaluate the functional outcome after cochlear implantation, the present study examined hemispheric asymmetries of AEPs to complex sound processing in CI users. Two dyadic tonal intervals were presented in an active oddball design as well as in a passive listening condition. Using independent component analysis (ICA), CI-related artefacts could be successfully reduced in EEGs of CI users (n=12). BESA dipole source analysis of recovered AEPs allowed for the evaluation of hemispheric differences in the primary auditory cortex. The results are remarkable for two reasons. First, they indicate altered hemispheric asymmetries for complex sound processing in CI users compared to normal-hearing listeners. Second, the results demonstrate that ICA can solve the problem of CI-related artefacts, thereby enabling a detailed investigation of auditory cortex activity in CI users. This is of utmost clinical relevance to make AEP applicable in investigating auditory cortical reorganization after cochlear implantation. Conference: 10th International Conference on Cognitive Neuroscience, Bodrum, Turkey, 1 Sep - 5 Sep, 2008. Presentation Type: Poster Presentation Topic: Cerebral Asymmetry Citation: Sandmann P, Eichele T, Debener S, Buechler M, Jancke L, Dillier N, Hugdahl K and Meyer M (2008). Altered hemispheric asymmetries of auditory evoked potentials after cochlear implantation. Conference Abstract: 10th International Conference on Cognitive Neuroscience. doi: 10.3389/conf.neuro.09.2009.01.149 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 05 Dec 2008; Published Online: 05 Dec 2008. * Correspondence: Pascale Sandmann, University of Zurich, Zurich, Switzerland, p.sandmann@psychologie.uzh.ch Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Pascale Sandmann T. Eichele S. Debener M. Buechler L. Jancke N. Dillier Kenneth Hugdahl M. Meyer Google Pascale Sandmann T. Eichele S. Debener M. Buechler L. Jancke N. Dillier Kenneth Hugdahl M. Meyer Google Scholar Pascale Sandmann T. Eichele S. Debener M. Buechler L. Jancke N. Dillier Kenneth Hugdahl M. Meyer PubMed Pascale Sandmann T. Eichele S. Debener M. Buechler L. Jancke N. Dillier Kenneth Hugdahl M. Meyer Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.