The article provides an overview of the concept of a multisensory environment and analyzes its possibilities for sensory-integrative education of first-graders at the stage of adaptation and younger schoolchildren from displaced families . The theoretical and methodological grounds for conducting an experiment in schools in Moscow and the Moscow region are considered in connection with the increasing number of first-graders who have problems at the stage of adaptation, and younger schoolchildren from displaced families who have problems integrating into a new socio-cultural environment for them. An overview of modern foreign and domestic research on the mental and physical development of children and factors contributing to learning difficulties is presented. The differences and unifying points are analyzed from the perspective of modern research in the field of sensory-integrative approach to understanding the lack of competence of teachers in working with younger displaced schoolchildren and first-graders at the stage of adaptation. One of the aspects of the psychological well-being of students in the educational process is the early identification and overcoming of learning difficulties in primary school. In conclusion, the authors consider the main problems and possibilities of organizing psychological and pedagogical support for the learning process in primary school based on an integrative approach (the concept of a multi-sensory environment), including through the training of specialists in this field to work with younger schoolchildren.