Laser deep penetration welding processes are sensitive towards contaminations inside of the process zone. Automized production facilities report the risk of residual packaging material within the process zone to result in seam defects. These can impair the mechanical properties of the seam and raise the demand for post-process quality control. In-line process monitoring is a promising tool to detect process anomalies correlated to such defects and potentially reduce the demand for time-consuming post-process control. This study investigates the influence of polystyrene particles, a common packaging material, enclosed in the gap of hidden T-joints onto the process dynamics. For process monitoring optical coherence tomography and airborne sound measurement were employed. The provoked process anomalies resulted in increased porosities and significant signal changes of the OCT and airborne sound measurements. This proves the in-line detection capability of process anomalies which occur due to polystyrene particles in joint gaps of hidden T-joints.