In traditional short-term hydropower scheduling problems, which usually determine the optimal power generation schedules within one week, the off-design zone of a hydraulic turbine is modeled as a forbidden zone due to the significantly increased risk of turbine damage when operating within this zone. However, it is still plausible to occasionally operate within this zone for short durations under real-world circumstances. With the integration of Variable Renewable Energy (VRE) into the power system, hydropower, as a dispatchable energy resource, operates complementarily with VRE to smooth overall power generation and enhance system performance. The rapid and frequent adjustments in output power make it inevitable for the hydraulic turbine to operate in the off-design zone. This paper introduces the operating zones associated with various production costs derived from fatigue analysis of the hydraulic turbine and calculated based on the turbine replacement cost. These costs are incorporated into a short-term hybrid scheduling tool based on Mixed Integer Linear Programming (MILP). Including production costs in the optimization problem shifts the turbine’s working point from a high-cost zone to a low-cost zone. The resulting production schedule for a Hydro-Solar hybrid power system considers not only short-term economic factors such as day-ahead market prices and water value but also lifetime hydraulic turbine cost, leading to a more comprehensive calculation of the production plan. This research provides valuable insights into the sustainable operation of hydropower plants, balancing short-term profits with lifetime hydraulic turbine costs.