Probable Loosening Research Articles

Mid-term Follow Up of a Highly Porous Acetabular Component for Primary Total Hip Arthroplasty.

As implant technology has continued to improve over the past decade, there has been an increase in the utilization of highly porous metal substrate acetabular components for primary total hip arthroplasty (THA). These implants have several theoretical benefits including a lower modulus of elasticity, which may result in a reduction in stress shielding, a higher coefficient of friction, which may enable better initial implant fixation, as well as higher porosity that may facilitate improved biological fixation. Although these components are implanted frequently, there are some studies that have posed concerns regarding radiographic evidence of loosening. Therefore, the purpose of this study was to assess: 1) The quality of fixation of porous metal acetabular components based on radiographs; 2) clinical outcomes; and 3) revision rates. A total of 159 patients (169 hips) who had undergone a primary THA utilizing a porous metal primary acetabular cup with minimum two-year follow up were assessed. The study cohort consisted of 51% women, had a mean age of 65 years (range, 30 to 92 years), a mean body mass index (BMI) of 29kg/m2 (range, 15 to 54), and a mean follow up of approximately four years (range, three to six years). Acetabular revision for component failure was documented. Radiographic assessments were independently performed by two fellowship-trained arthroplasty surgeons to determine implant stability and radiolucencies. Clinical evaluations were made by assessing the hip disability and osteoarthritis outcome score (HOOS-Jr) survey scores. Failure was defined as the need to revise the acetabular component, for either septic or aseptic pathology. At final follow up, one patient had definitive loosening, one had probable loosening, and three patients had possible loosening. Only 3.0% had radiolucencies or radiosclerotic lesions in at least one zone. Of these patients, three developed progressive radiolucencies. All patients achieved excellent postoperative HOOS-Jr scores, and no significant differences were noted between patients who did not have loosening compared to patients who had possible or probable loosening. Only two patients underwent revision for aseptic loosening of the cup (success rate for this implant was 98.8% [2/169]). There is a paucity of studies focused on the results of this porous metal substrate acetabular component, with some of the current literature reporting conflicting outcomes. Our study reported a low acetabular revision rate of only 1.2% at an approximate mean follow up of four years. The incidence of radiolucencies and progressive radiolucencies were lower (3.0%) than has been found in some studies. Overall, the results of this study support the utilization of this acetabular component in appropriately indicated patients. These data show a low rate of acetabular revision at mean four-year follow up.

Endofemoral Shooting Technique for Removing Well-fixed Cementless Stems

BackgroundThe removal of a well-fixed cementless stem poses technical challenges. The aim of this study was to evaluate the outcomes of our endofemoral extraction technique established in 2001. MethodsBetween January 2001 and December 2016, 118 consecutive revisions following bipolar or total hip arthroplasty, which required cementless femoral stem removal, were performed at our institution. This retrospective study evaluated 106 patients (108 hips) who were followed up for a mean of 9.2 years (range, 5-20 years). The patients included 15 men and 91 women with a mean age of 65 years (range, 33-87 years). Endofemoral extracted stem removal was performed as follows. Multiple Kirschner wires were sequentially inserted into the interface between the implant and cortical bone, after which the implant was detached using a thin chisel. After the cementless stem was removed, it was replaced with a cemented stem using an autograft, as needed. Radiological loosening of the femoral stem was defined as definite or probable loosening, based on the criteria of Harris et al. Prosthesis survival was analyzed using the Kaplan-Meier method, with the endpoint set as repeat revision surgery for stem loosening or femoral fracture. ResultsRe-revision surgery was performed in 7 hips. Stem loosening was observed in 4 hips, and the mean subsidence was 0.3 mm (0-3 mm). The 10-year survival rate was 97.7% (95% confidence interval, 93.2-100). ConclusionsOur technique for removing well-fixed cementless stems yielded successful results.

Total hip arthroplasty in severe segmental femoral bone loss situations: Use of a reconstruction modular stem design (JVC IX™)

Management of extensive proximal femur bone loss secondary to tumor resection or major osteolysis remains controversial. The possible options include a composite allograft/stem prosthesis, a modular type megaprosthesis or a custom-made megaprosthesis. Modularity allows versatility at reconstruction and avoids the delay required manufacturing a custom-made implant. Hypothesis and type of study: A retrospective radiological and clinical study investigated whether a special reconstruction modular stem design (JVC IX) would provide medium term success in the treatment of severe proximal femur bone loss. Between 1995 and 2005, 23 JVC IX hip replacements were performed for severe segmental proximal femur bone loss. Etiology was: 13 cases of tumor resection, eight of extensive osteolysis secondary to femoral implant loosening, and two traumatic situations. Follow-up was annual. Functional assessment used the Musculo-Skeletal Tumor Score (MSTS), and implant survival rates underwent Kaplan-Meier analysis, with surgical revision (to replace or remove the implant) as the end point. All 23 patients (23 hips) were followed up for a mean 5.4 years (+/-3.7 yrs). Mean MSTS was 16.2 (max.=30). All stems demonstrated good fixation at radiological assessment, except for one case of probable loosening in contact with a metastatic osteolysis. Four implants had to be revised: two for non-controlled infection, one for tumor extension, and one for stem fatigue fracture. At 10 years' follow-up, implant survivorship was 81.5% (range: 62% to 100%). Severe proximal femur bone loss is a difficult situation to deal with, offering no ideal treatment option. Modular megaprostheses are salvage procedures. Their results at a mean 5.4 years' follow-up are encouraging, and appear comparable to the ones obtained with alternative solutions (composite allograft/stem prostheses). Level IV retrospective, therapeutic study.

Cementless total hip arthroplasty in Paget's disease of bone: a retrospective review.

Paget's disease of bone (PDB) is a localised chronic osteopathy leading to bone deformities, bone hypervascularity, structural weakness and altered joint biomechanics. The pelvis and upper femur are frequently involved, resulting in disabling hip disease, and total hip arthroplasty (THA) may be required. We performed a retrospective study on the management and the outcome of 39 uncemented hydroxyapatite fully-coated THA in patients with PDB of the hip. The follow-up averaged 79.4 months (range 24-194). Functional scores improved significantly and, using the Harris hip score, 84% of patients had an excellent clinical outcome at the latest follow-up. Despite one case of an uncemented acetabular component with probable loosening, no implant revision had been required at our latest follow-up. Signs of implant loosening were found to be significantly more frequent in patients with active disease. For this reason, we advocate the use of pre-operative medication with bisphosphonates to reduce disease activity. Another benefit of this treatment is the significant decrease of intra-operative blood loss. Provided the control of disease activity in the pre-operative period with bisphosphonates is achieved, good outcome of cementless THAs can be expected. Bisphosphonates reduced the risk of implant loosening and excessive intra-operative blood loss.

Trabecular Metal™ Cups for Acetabular Defects With 50% or Less Host Bone Contact

Acetabular component revision in the context of large contained bone defects with less than 50% host bone contact traditionally have been treated with roof reinforcement or antiprotrusio cages. Trabecular Metal cups (Zimmer, Inc, Warsaw, IN) may offer a reasonable treatment alternative. We evaluated the clinical and radiographic outcome of this mode of treatment. We prospectively followed 53 hip revision acetabular arthroplasty procedures performed with Trabecular Metal cups for contained defects with 50% or less contact with native bone. All patients were clinically and radiographically evaluated for evidence of loosening or failure. Minimum followup was 24 months (average, 45 months; range, 24-71 months). Contact with host bone ranged from 0% to 50% (average, 19%). The mean postoperative Merle d'Aubigne-Postel score was 10.6 (range, 1-12), with a mean improvement of 5.2 (range, -4-10) compared to the preoperative score. Two failed cups (4%) were revised. Two additional cups (4%) had radiographic evidence of probable loosening. Complications included four dislocations and one sciatic nerve palsy. The data suggest treatment of cavitary defects with less than 50% host bone contact using Trabecular Metal cups, without structural support by augments or structural bone grafts, is a reasonable option.

Échec par descellement aseptique précoce de la cupule acétabulaire cimentée de prothèses totales de hanche à couple de frottement métal-métal

Purpose of the study The aim of this study was to report cases of acetabular failure of metal-on-metal total hip arthroplasties using cemented cups with a metal-metal bearing. Material and methods From 1997 to 1999, 137 patients underwent total hip arthroplasty with a 28-mm head and a metal-metal (Metasul ®) bearing. At mean follow-up of three years eight months (range 2-6 years), three patients had died and thirteen were lost to follow-up or had less than 2 years follow-up. The analysis thus included 118 patients (122 hips) 67 women and 51 men (mean age 61 years). The same transgluteal approach with two cemented implants (Palacos ® gentamycine) was used in all patients. The Postel-Merle-d’Aubigné score was used for clinical assessment with search for lucent lines in the Delee and Charnley zones and cup migration on the standard x-rays. Actuarial survival curves were drawn using revision and failure as the end events. Results In this series, there were no cases of dislocation or infection but there were five revisions for aseptic cup loosening: one at two years, two at four years, and two at five years. Among the remaining 117 implants, outcome was clinically very good in 101, good in 10 and fair in 6. Radiologically, there were no cases of femoral lucent lines, migration or osteolysis. For the cup, a lucent line measuring less than 1 mm and stable was observed in 81 hips. A progressive lucent line was observed in 18 hips with 11 showing signs of probable loosening. The five-year survival using surgical revision as the endpoint was 94%. Using cup failure (revision and progressive line), it was 80%. Revisions and radiographically probable loosenings were statistically more significant in small cups measuring 44 and 46 mm. Discussion In this series, cemented metal-on-metal bearings showed a rate of failure greater than observed in metal-polyethylene implants and metal-on-metal implants using a press fit cup. Other series using a metal-on-metal bearing with a cemented cup have found the same trend. Conclusion We have discontinued this type of implant and recommend avoiding direct cementing of the polyethylene-metasul cup on the bone for total hip arthroplasty. The metal-on-metal bearing can still be used, but without cementing the cup.

Total hip replacement with a superolateral bone graft for osteoarthritis secondary to dysplasia

We evaluated the long-term results of 116 total hip replacements with a superolateral shelfplasty in 102 patients with osteoarthritis secondary to developmental dysplasia of the hip. After a mean follow-up of 19.5 years (11.5 to 26.0), 14 acetabular components (12%) had been revised. The cumulative survival at 20 years was 78%, with revision for loosening of the acetabular component as the end-point. All grafts were well integrated and showed remodelling. In six grafts some resorption had occurred under the heads of the screws where the graft was not supporting the socket. Apart from these 14 revisions, seven acetabular components had possible radiological signs of loosening at a mean follow-up of 14.5 years, one had signs of probable loosening, and five had signs of definite loosening. These results indicate that this technique of bone grafting for acetabular reconstruction in hip dysplasia is a durable solution for cemented acetabular components.

Revision of cemented hip arthroplasty using a hydroxyapatite-ceramic-coated femoral component

We report the clinical and radiological outcome of 86 revisions of cemented hip arthroplasties using JRI-Furlong hydroxyapatite-ceramic-coated acetabular and femoral components. The acetabular component was revised in 62 hips and the femoral component in all hips. The mean follow-up was 12.6 years and no patient was lost to follow-up. The mean age of the patients was 71.2 years. The mean Harris hip and Oxford scores were 82 (59 to 96) and 23.4 (14 to 40), respectively. The mean Charnley modification of the Merle d'Aubigné and Postel score was 5 (3 to 6) for pain, 4.9 (3 to 6) for movement and 4.4 (3 to 6) for mobility. Migration of the acetabular component was seen in two hips and the mean acetabular inclination was 42.6 degrees. The mean linear polyethylene wear was 0.05 mm/year. The mean subsidence of the femoral component was 1.9 mm and stress shielding was seen in 23 (28%) with bony ingrowth in 76 (94%). Heterotopic ossification was seen in 12 hips (15%). There were three re-revisions, two for deep sepsis and one for recurrent dislocation and there were no re-revisions for aseptic loosening. The mean EuroQol EQ-5D description scores and health thermometer scores were 0.69 (0.51 to 0.89) and 79 (54 to 95), respectively. With an end-point of definite or probable loosening, the probability of survival at 12 years was 93.9% and 95.6% for the acetabular and femoral components, respectively. Overall survival at 12 years, with removal or further revision of either component for any reason as the end-point, was 92.3%. Our study supports the continued use of this arthroplasty and documents the durability of hydroxyapatite-ceramic-coated components.

Is titanium so bad? Medium-term outcome of cemented titanium stems.

Early failures have seen titanium fall from favour as a material for cemented femoral stems. Between 1989 and 1994, we performed a prospective review of a consecutive series of 122 cemented total hip replacements using the Ultima straight textured titanium stem, and report the five- to ten-year clinical and radiological outcomes. There were no revisions for loosening of the femoral stem. Revision surgery was undertaken for other reasons such as dislocation, infection and loosening of the cup in 7.3%. Of those patients without revision all but two were satisfied with their hip, with 74% graded good or excellent using a modified Harris hip score. Radiological assessment revealed probable loosening in two. Although slight vertical subsidence was found in one-third of patients it had not progressed to loosening. It is not clear whether this represents debonding. Non-progressive radiolucent lines (1 to 2 mm) were present in zone 1 at the cement-prosthesis interface in 14.7%. Calcar resorption and hypertrophy around the distal stem were not often seen. With 97% survival at a mean of 7.5 years, the medium-term results of this specific cemented titanium stem are reassuring so far, but we are concerned about debonding and future failure.

Is titanium so bad?

Early failures have seen titanium fall from favour as a material for cemented femoral stems. Between 1989 and 1994, we performed a prospective review of a consecutive series of 122 cemented total hip replacements using the Ultima straight textured titanium stem, and report the five- to ten-year clinical and radiological outcomes. There were no revisions for loosening of the femoral stem. Revision surgery was undertaken for other reasons such as dislocation, infection and loosening of the cup in 7.3%. Of those patients without revision all but two were satisfied with their hip, with 74% graded good or excellent using a modified Harris hip score. Radiological assessment revealed probable loosening in two. Although slight vertical subsidence was found in one-third of patients it had not progressed to loosening. It is not clear whether this represents debonding. Non-progressive radiolucent lines (1 to 2 mm) were present in zone 1 at the cement-prosthesis interface in 14.7%. Calcar resorption and hypertrophy around the distal stem were not often seen. With 97% survival at a mean of 7.5 years, the medium-term results of this specific cemented titanium stem are reassuring so far, but we are concerned about debonding and future failure.

TOTAL HIP ARTHROPLASTY WITH CEMENT IN PATIENTS LESS THAN TWENTY YEARS OLD. LONG-TERM RESULTS

Sixty-three consecutive total hip arthroplasties were performed with cement in fifty adolescent patients from 1972 through 1980, and the results were determined after a minimum of ten years. A polyethylene cup without a metal backing and a non-modular femoral component with a collar and a fixed neck length were inserted, with use of so-called first-generation cementing techniques, in each hip. Kaplan-Meier survival analysis of all sixty-three hips demonstrated that the probability of failure (defined as revision or symptomatic loosening) increased steadily over time and reached 45 per cent after fifteen years. A number of specific variables were associated with a significantly higher probability of failure: a history of more than one previous procedure involving the hip (p = 0.0002), unilateral arthroplasty (p = 0.006), previous trauma involving the hip (p = 0.01), the absence of other disease that limited function of the ipsilateral lower extremity (p = 0.03), a high postoperative level of activity (involving moderate or strenuous manual labor) (p = 0.03), and a preoperative weight of more than sixty kilograms (p = 0.03). The probability of failure in the patients who had inflammatory arthritis (11 per cent) was significantly lower than that in those who had previous trauma involving the hip (47 per cent) (p = 0.0006). Fifty-two hips (forty patients) were followed for a minimum of ten years or until revision. The mean duration of follow-up for these fifty-two hips was 12.6 years (range, 1.6 to 18.6 years). The result was evaluated clinically and radiographically with use of the Mayo hip-scoring system and was graded as excellent in ten hips (19 per cent), good in sixteen (31 per cent), fair in one (2 per cent), and poor in twenty-five (48 per cent). Most of the poor results were due to symptomatic loosening of the acetabular component. The probability of radiographic loosening after fifteen years was 60 per cent for the acetabular component and 20 per cent for the femoral component. Radiographic evidence of polyethylene wear was associated with probable loosening of the acetabular component (p = 0.03). The findings of the present study suggest that total hip arthroplasty in adolescents should be reserved for carefully selected patients for whom alternative procedures are contraindicated or unacceptable. Fixation of the acetabular component with cement is not recommended in this setting.

Total Hip Arthroplasty with Cement in Patients Less Than Twenty Years Old. Long-Term Results*

Sixty-three consecutive total hip arthroplasties were performed with cement in fifty adolescent patients from 1972 through 1980, and the results were determined after a minimum of ten years. A polyethylene cup without a metal backing and a non-modular femoral component with a collar and a fixed neck length were inserted, with use of so-called first-generation cementing techniques, in each hip. Kaplan-Meier survival analysis of all sixty-three hips demonstrated that the probability of failure (defined as revision or symptomatic loosening) increased steadily over time and reached 45 per cent after fifteen years. A number of specific variables were associated with a significantly higher probability of failure: a history of more than one previous procedure involving the hip (p = 0.0002), unilateral arthroplasty (p = 0.006), previous trauma involving the hip (p = 0.01), the absence of other disease that limited function of the ipsilateral lower extremity (p = 0.03), a high postoperative level of activity (involving moderate or strenuous manual labor) (p = 0.03), and a preoperative weight of more than sixty kilograms (p = 0.03). The probability of failure in the patients who had inflammatory arthritis (11 per cent) was significantly lower than that in those who had previous trauma involving the hip (47 per cent) (p = 0.0006). Fifty-two hips (forty patients) were followed for a minimum of ten years or until revision. The mean duration of follow-up for these fifty-two hips was 12.6 years (range, 1.6 to 18.6 years). The result was evaluated clinically and radiographically with use of the Mayo hip-scoring system and was graded as excellent in ten hips (19 per cent), good in sixteen (31 per cent), fair in one (2 per cent), and poor in twenty-five (48 per cent). Most of the poor results were due to symptomatic loosening of the acetabular component. The probability of radiographic loosening after fifteen years was 60 per cent for the acetabular component and 20 per cent for the femoral component. Radiographic evidence of polyethylene wear was associated with probable loosening of the acetabular component (p = 0.03). The findings of the present study suggest that total hip arthroplasty in adolescents should be reserved for carefully selected patients for whom alternative procedures are contraindicated or unacceptable. Fixation of the acetabular component with cement is not recommended in this setting.

The Nicolas Andry Award

A prospective randomized clinical trial comparing cemented to cementless total hip arthroplasty has been ongoing at the author's institution since 1987. All parameters assessed showed that there was no statistically significant difference in any of the health related quality of life measures used when patients with cement were compared with patients without cement at any of the followup periods as many as 4 years later. The improvement was dramatic and sustained. No components (cemented or cementless) have been revised to date (average, 4.8 years). A radiographic analysis showed probable loosening of the cemented socket in 24% and presumed minimal pelvic osteolysis in 8%. The cementless sockets showed a greater frequency and severity of pelvic osteolysis (14%). The cemented femoral component was judged to be possibly loose in 10%; however, none were considered probably loose. The patients who had cementless femoral components were doing extremely well with the components showing very little subsidence or proximal stress protection noted. Osteolysis on the femoral side was not seen in any of the cementless stems. Total hip replacement gives comparable clinical results when health related quality of life measures are analyzed; however, metal backed cemented acetabular components have a high rate of radiographic failure. Short-term stability of a non-cemented porous coated titanium stem, however, gave excellent clinical and radiographic results.

Revision total hip arthroplasty with cement after cup arthroplasty. Long-term follow-up.

Ninety-six cup arthroplasties (eighty-three patients) were converted to total hip arthroplasties with cement between July 1970 and August 1982. Fifty-eight hips (fifty patients) were followed for at least ten years, or to failure after a shorter interval, and eight other hips (eight patients) had a subsequent operation because of a deep infection. Of the fifty-eight hips that were followed for at least ten years or to failure, nine (16 per cent) were revised because of aseptic loosening of the acetabular component, one (2 per cent) was revised because of a traumatic fracture of the femur, and none were revised because of loosening of the femoral component. Kaplan-Meier survivorship analysis with revision for any reason (including infection) as the end point showed a rate of survival of 92 +/- 6 per cent (average and 95 per cent confidence interval) at ten years and of 74 +/- 12 per cent at twenty years. When the hips in which an infection had occurred were excluded, and with revision because of aseptic loosening of the acetabular component as the end point, the rate of survival was 84 +/- 10 per cent at twenty years; no acetabular component was revised because of aseptic loosening in the first ten years. When the hips in which an infection had occurred were excluded, and with radiographic evidence of definite or probable loosening of the acetabular component, or aseptic loosening of the acetabular component necessitating revision, as the end point, the rate of survival was 91 +/- 6 per cent at ten years and 53 +/- 22 per cent at twenty years. The present study demonstrates the durability of total hip replacement with cement after the failure of a cup arthroplasty and further substantiates the excellent long-term clinical and radiographic results that can be obtained with insertion of a femoral component with cement.

Results of Cemented Femoral Revision Total Hip Arthroplasty Using Improved Cementing Techniques

Seventy-nine consecutive femoral component revision total hip arthroplasties done in 73 patients from 1977 to 1983 using a distal intramedullary cement plug and a cement gun delivery system were evaluated to determine if improved results were obtained with newer cementing techniques. At a minimum 10-year followup interval, only 1 patient was not available for followup and 47 hips had minimum 10-year followup radiographs. The incidence of femoral rerevision for aseptic loosening was 9.5% for those hips with minimum 10-year followup and 5.4% for the entire group. The incidence of radiographic femoral failure (defined as a revision or definite or probable loosening) was 26.1% for those hips followed for a minimum of 10 years and 16.3% for the entire group. Compared with historical controls, these results represent an improvement over those reported with the use of earlier cementing techniques.

Total hip arthroplasty after failed intertrochanteric osteotomy

From 1969 through 1982, 305 hips in 290 patients had total hip arthroplasty for failed femoral intertrochanteric osteotomy. Of these, we reviewed 215 hips (70.5%) with a minimum follow-up of five years. The results were good or excellent in 79%, but there were technical problems at operation in 23% and a total perioperative complication rate of 11.8%. Late complications occurred in 13.1% including seven late infections (3.2%). At a mean follow-up of ten years, 39 hips had been revised (18.1%), there was probable loosening in 19.5% of stems and 12.6% of cups and possible loosening in 11.4% of stems and 7.2% of cups. The cumulative probability of failure at ten years was 20.6%. We recommend that intertrochanteric osteotomy be advised, planned and executed bearing in mind the possible need for a subsequent total hip arthroplasty, and that screws and plates should be routinely removed soon after union of the osteotomy.

Total shoulder arthroplasty with a tissue-ingrowth glenoid component

A newly designed, uncemented, tissue-ingrowth glenoid component with a porous surface was used in association with the Neer humeral head prosthesis for 32 total shoulder arthroplasties in 29 patients. The diagnoses for the shoulders were osteoarthritis in 17, rheumatoid arthritis in eight, and traumatic arthritis in seven. Follow-up evaluations averaged 51 months (range, 29 to 80 months). Five complications occurred, necessitating four reoperations: two for glenoid component dissociation, one for humeral loosening, and one for infection. Little or no pain was experienced after the operation in 27 (96%) of the 28 shoulders that required no additional surgery. Average active abduction was 145°, average external rotation was 59°, and median internal rotation was to 112. Three glenoid components had probable loosening on radiographic examination. Eight shoulders had some degree of instability; a complication related to the glenoid component (polyethylene dissociation) or probable loosening not yet requiring reoperation developed in four of these (p < 0.02). These data support the continuing use of an uncemented, tissue-ingrowth glenoid component in arthritic shoulders with adequate bone support. Joint instability must be avoided to lessen complications and the need for revision surgery.

Complications with revision of the femoral component of total hip arthroplasty: Comparison between cemented and uncemented techniques

The intraoperative and early postoperative complications of femoral component revision surgery in a group of 94 treated with a cemented femoral implant and 91 treated with a specific (Bias, Zimmer International, Warsaw, IN) uncemented femoral implant were assessed. Follow-up of at least 2 years for both groups was obtained, averaging 4.5 years and 3.2 years, respectively. The Harris hip score was 45 and 81 before and after the cemented revision and 42 and 84 for the uncemented procedure. The overall complication rate was 41% and 34%, respectively, which is not statistically different. The major differences consist of radiographic evidence of probable loosening in 53% of the cemented population and at least 2 mm of subsidence in 45% of the uncemented group. Fracture occurred in 3% and 18%, respectively, and caused failure in one with cemented and three with uncemented revisions. The reoperation rate was 15% and 12%, respectively. In these patient populations, uncemented femoral revision was a satisfactory technique, having a complication rate comparable to and radiographic features more favorable than what was present with the cemented revision procedure. Long-term follow-up is necessary to determine more fully the role of uncemented implants for femoral component revision.

Charnley total hip arthroplasty with cement. Fifteen-year results.

The results of the first 333 Charnley total hip arthroplasties that were performed with cement at the Mayo Clinic were reviewed a minimum of fifteen years postoperatively. Data were available for 166 of 170 hips of patients who were still alive. One hundred and thirty patients died, and thirty-seven hips were revised. At the time of this study, 80 per cent of the living patients had no pain, and 152 of the 160 hips remained much better than before the operation. Kaplan-Meier analysis of probable loosening of one or both components, on the basis of roentgenographic evidence, demonstrated a probability of loosening of 3 per cent incidence at one year after operation, 13 per cent at five years, 19 per cent at ten years, and 32 per cent at fifteen years. The probability of failure (that is, revision or symptomatic loosening) was 0.9 per cent at one year, 4.1 per cent at five years, 8.9 per cent at ten years, and 12.7 per cent at fifteen years. We did not identify a dramatic increase in the incidence of loosening or failure at any of the follow-up periods (one, five, ten, or fifteen years). With the Mayo Clinic clinical and roentgenographic system for scoring the hips, we found that ninety-seven hips had a good or excellent result; fifteen, a fair result; and thirteen, a poor result. (The scoring could not be completed for forty-one hips). The functional results deteriorated slightly over time.(ABSTRACT TRUNCATED AT 250 WORDS)

Multiple revisions for failed total hip arthroplasty not associated with infection.

Forty-five patients (forty-five hips) underwent repeat revisions of a total hip arthroplasty that had failed but was not associated with infection; seven of these patients had a third revision. The mean length of follow-up was approximately three years, and no patients were lost to follow-up. Twenty-eight of the forty-five patients had no or slight pain after the second revision, and thirty reported that their condition was improved. After the third revision, six patients had no or only slight pain, and five said that their condition was improved. On final roentgenographic examination, there was probable loosening (migration or subsidence of a component, lucency at the prosthesis-cement interface, fracture of the cement, or complete radiolucency at the bone-cement, or complete radiolucency at the bone-cement interface of more than one millimeter in at least one zone) of eight of the acetabular components and thirteen of the femoral components after the second revision and three acetabular components and one femoral component after the third. There was symptomatic loosening (moderate or severe pain and probable roentgenographic loosening) in six patients after the second revision and one after the third. Significant postoperative complications were noted in nineteen of the forty-five patients, and treatment was considered to be a failure in eleven hips after the second revision and in two after the third.