The goal of this paper was to explore the relationship between aggressive behavior and emotional self-control skills in middle school students, along with examining the current status of reactive and proactive aggression and emotional self-control skills in students. A total of 1,235 students in grades 6, 7, and 8 in Hanoi, Nghe An, and Ho Chi Minh city participated in the study by answering a set of questions including the Proactive and Reactive Aggression Questionnaire (PRQ, Raine et al., 2006); Aggression Scale (AS - Aggression Scale, Orpinas and Frankowski, 2001); The Basic Empathy Scale (BES, Jolliffe et al., 2006) and emotional self-control skills scale. Research results from this quantitative research illustrated that middle school students demonstrate aggressive behavior at an average level, mainly occasionally performing this behavior but the proportion of secondary students regularly performing aggressive behavior was quite high. There was a negative correlation between aggressive behavior and emotional self-control skills in students; emotional self-control skills and empathy were predictors of aggressive behavior. The analysis, interpretation of results, as well as limitations of the current study, were also discussed in the discussion section of this paper.