We propose an improved superpixel segmentation algorithm based on visual saliency and color entropy for online color detection in printed products. This method addresses the issues of low accuracy and slow speed in detecting color deviations in print quality control. The improved superpixel segmentation algorithm consists of three main steps: Firstly, simulating human visual perception to obtain visually salient regions of the image, thereby achieving region-based superpixel segmentation. Secondly, adaptively determining the superpixel size within the salient regions using color information entropy. Finally, the superpixel segmentation method is optimized using hue angle distance based on chromaticity, ultimately achieving a region-based adaptive superpixel segmentation algorithm. Color detection of printed products compares the color mean values of post-printing images under the same superpixel labels, outputting labels with color deviations to identify areas of color differences. The experimental results show that the improved superpixel algorithm introduces color phase distance with better segmentation accuracy, and combines it with human visual perception to better reproduce the color information of printed materials. Using the method described in this article for printing color quality inspection can reduce data computation, quickly detect and mark color difference areas, and provide the degree of color deviation.