Primary Retroperitoneal Mucinous Cystadenoma Research Articles

An enormous benign primary retroperitoneal mucinous cystadenoma: a case report and literature review of a seldom seen abdominal pathology.

Retroperitoneal neoplasia comprise less than 2% of all tumours. benign primary retroperitoneal mucinous cystadenoma (PRMC) is an extremely rare tumour. Their clinical course is overall silent unless the patient presents with a vague abdominal or pelvic pain, abdominal distention, or a palpable mass. Their aetiology remains theorized and since 1989, only 46 cases (excluding ours) worldwide were documented in the literature. The majority of cases were discovered in females but the overall tumour incidence rate is still undetermined due to its rarity. Well-timed recognition of this pathology permits the necessary curative surgical intervention to take place. We hereby illustrate the rare case of a 23-year-old female who presented to the surgical clinic complaining solely of an unexplained gradual increase of the abdominal contour. Their presurgical radiological analysis yielded an intraabdominal large-sized well-demarcated retroperitoneal mass. Thorough resection of the mass was accomplished via open surgery. The subsequent microscopic analysis of excised tumour yielded the diagnosis of primary retroperitoneal mucinous cystadenoma of benign nature. Primary retroperitoneal mucinous cystadenoma is a seldom seen tumour. The scarcity of its occurrence is further highlighted by the published data. Based on their conclusive review of the available published English-based literature, ours is the 47th documented case of a benign PRMC and it is the first documented case from our country; Syria. The impact of these findings warrants raising awareness on the subject and considering PRMC as a differential diagnosis when presented with a similar case in the clinical practice.

Primary retroperitoneal mucinous cystadenoma in a female patient: A case report.

IntroductionPrimary retroperitoneal mucinous cystadenoma is an extremely uncommon tumor occurring mostly in females. The histogenesis of PRMC remains unclear and Open surgery is the most impressive treatment.Case presentationWe present a 20-year-old Iranian woman with history of intermittent abdominal pain. In physical examination, her abdomen had a mildly asymmetrical distention and a round shape mass was palpated in right abdomen also she had a mild tenderness in right abdomen. Radiologic assessment revealed a right retroperitoneal smooth cystic mass (20 × 15 cm) without invasive features. The patient underwent complete surgical excision of the tumor by a laparotomic approach because of its size. The lesion was gently dissected from the contiguous organs and removed completely without spillage of its content. In microscopic investigations, sections showed a unilocular cyst with fibrous wall lined via monolayered bland looking columnar mucinous epithelium and no atypia or stromal invasion was presented. Diagnosis of a PRMC was made. The patient has discharged without any complications in 2 days' postoperative course.DiscussionGenerally, cysts are asymptomatic and are found fortuitously after a routine checkup assessment. Symptoms and signs related to this cyst are mainly because of their huge size and compression effect. Radiological assessments are effective in specifying the lesion preoperatively; although, the final diagnosis always needs histopathological verification.ConclusionWhen the tumor is diagnosed, full resection should be considered because of the infectious or malignant potential of the tumor.

Large primary retroperitoneal mucinous cystadenoma managed laparoscopically: Case report and literature review

Background: Retroperitoneal cystic lesions (RCLs) are uncommon clinical findings that arise within the retroperitoneal compartments and account for various etiologies. They can be benign or malignant in nature and may present with different manifestations. Case report: A 55-year-old woman presented with nonspecific right sided abdominal pain. Ultrasound detected a large cyst in the right retroperitoneal region, computed tomography revealed a large well-defined cystic lesion measuring 13 X 9 X 6 cm in the right posterior peritoneum extending from the subhepatic area to the right pelvis. Laparoscopic complete resection performed with uneventful perioperative course. Histopathologic findings were suggestive of mucinous cystadenoma. Conclusion: Primary Retroperitoneal Mucinous Cystadenoma (PRMC) is an extremely rare pathology that can pose some challenge for clinicians. Awareness of this entity can help us in establishing the diagnosis and provide an optimal management. Although laparotomy is considered the standard approach of huge mucinous cystadenomas; laparoscopic surgery can be a safe and adequate therapeutic option. Keywords: retroperitoneal cystic lesions (RCL); primary retroperitoneal mucinous cystadenomas (PRMCs); cystadenoma; mucinous; laparoscopy.

Laparoscopic Resection of a Giant Dedifferentiated Primary Retroperitoneal Mucinous Cystadenoma (PRMC) in a Young Woman: A Case Report and Literature Review

Background: PRMC is a very rare benign tumor of the abdominal cavity that usually occurs in women, and PRMC demonstrate no specific findings on CT. There are many reports on the differential diagnosis and discussion of PRMC imaging, but there are few reports on the treatment of dedifferentiated PRMC using laparoscopic resection and postoperative follow-up.

Primary retroperitoneal mucinous cystadenoma in a male patient: a case report

Primary retroperitoneal mucinous cystic neoplasms are very rare, especially in men. To our knowledge, only 13 cases of such neoplasms have been reported in men to date. The most common type is the primary retroperitoneal mucinous cystadenoma, which almost invariably affects females. Most patients present with non-specific symptoms. In this case report, we will describe a case of a 53 year old male patient who presented with raised CEA tumour marker and vague right sided abdominal discomfort. A computed tomography (CT) scan was performed, which revealed a 4.9 × 4.7 × 7.5 cm lobulated retroperitoneal cystic lesion abutting the posterior wall of the mid ascending colon. A laparoscopic excision was eventually performed with complete removal of the retroperitoneal cystic lesion. Subsequent histological assessment confirmed the diagnosis of a primary retroperitoneal mucinous cystadenoma with borderline malignancy. On comparison with a prior CT scan performed about seven and a half years earlier, we managed to derive a doubling rate of about 626 days, which is the first reported case in English literature to document the growth rate of such a tumour. The patient has since been discharged well, with no evidence of tumour recurrence on an interval CT scan.

Primarni retroperitonealni mucinozni cistadenom – prikaz slučaja

Objective. Primary retroperitoneal mucinous cystadenoma is rare, appearing more commonly in women and very rarely in men. Case report. We present a 50-year-old female with retroperitoneal cystic formation under the left kidney seen accidentally during an ultrasonographic examination. The cyst measuring 88x77 mm, with an irregular shape, smooth walls with several small cystic formations at the bottom was seen. Cystic echinococcosis was considered in the differential diagnosis and IHA echinococcosis and ELISA echinococcosis tests were performed. Biohumoral and tumor markers were normal. Repeated ultrasound examination showed both kidneys of normal dimensions, parenchyma thickness and echogenicity, with no signs of hydronephrosis and calculosis. Each kidney had cortical cyst, beside the cyst of about 25 mm in diameter in the left kidney. CT revealed left-sided infrarenal retroperitoneal tumor and MRI of the abdomen and pelvis was proposed because of the size, density and calcification of the tumor wall. MRI shows multilocularis cystic formation with septations measuring 92x76 mm, with several small cystic lesions filled with dense content, caudal to the left kidney and between intestinal wings. In order to clarify the etiology of the described changes and because the patient was suffering from abdominal pain laparotomy was performed and retroperitoneal cyst size 100x70x80 mm was extirpated in toto. After a successful operation the postoperative period was uneventful. Pathohistological finding showed retroperitoneal mucinous cystadenoma. Conclusion. Primary retroperitoneal mucinous cystadenoma is a rare tumor, difficult to diagnose. Definite diagnosis is based upon histopathology. The treatment is exclusively surgical.

Primary Retroperitoneal Mucinous Cystadenoma.

Mucinous cystadenomas and cystadenocarcinomas of the ovary are clinically and histopathologically well-established common tumors. However, primary retroperitoneal mucinous cystic tumors are extremely rare, and although their histopathogenesis is still uncertain, several theories have been proposed. Most authors suggest that they develop through mucinous metaplasia in a preexisting mesothelium-lined cyst. An accurate preoperative diagnosis of these tumors is difficult because no effective diagnostic measures have been established. Delay in diagnosis and treatment of this tumor may be fatal for the patient because of complications such as rupture, infection, and malignant transformation. We describe the case of a 31-year-old woman with abdominal pain and a palpable mass. Computed tomography of the abdomen revealed a retroperitoneal cystic mass, which was resected successfully through laparoscopy. Histopathological examination of the resected mass confirmed the diagnosis of a primary retroperitoneal mucinous cystadenoma. The patient was discharged on postoperative day 5 without any complications.

Primary retroperitoneal benign mucinous cystadenoma in a male

Introduction: Retroperitoneal mucinous cystadenoma is extremely rare, prevailing specifically in female gender, with unclear histogenesis. Only three cases concerning male patients have been reported. Case Report: We report a case of a 75-year-old male presented with right flank pain and a palpable mass. An abdominal computed tomography scan revealed a retroperitoneal tumor resulting after the histological examination to a primary retroperitoneal mucinous cystadenoma. Conclusion: This is the fourth case of primary retroperitoneal mucinous cystadenoma of benign type in a male reported in literature. Several hypotheses may explain the histogenesis of this pathological process. Radical resection is the treatment of choice.

Primary retroperitoneal mucinous cystadenoma: A case report

Primary retroperitoneal mucinous cystic tumors are extremely rare. These tumors can be classified as a primary retroperitoneal mucinous cystadenoma with or without borderline malignancy or primary retroperitoneal mucinous cystadenocarcinoma. The most common of these is primary retroperitoneal mucinous cystadenoma, which almost always occurs in female patients; only ten cases have been reported in males. The most common clinical findings for this tumor type include nonspecific abdominal pain and a palpable abdominal mass. A definitive diagnosis is usually obtained from histopathology after surgical excision. Here, we report the case of a 60-year-old female patient who complained of abdominal pain that had been present for 3 mo and presented with a palpable abdominal mass. Multidetector computed tomography scanning revealed a large, unilocular cystic mass in the left retroperitoneal space. Surgical intervention was performed and the tumor was completely removed. Histopathologic examination confirmed that the tumor was a primary retroperitoneal mucinous cystadenoma. Two years after surgery, the patient remains disease free.

A Case of Primary Retroperitoneal Mucinous Cystadenoma Arising from the Retropancreatic Area

Primary retroperitoneal mucinous cystadenoma is an extremely uncommon tumor, even though mucinous cystadenoma often develops in the ovary and less frequently in the pancreas. A 21-year-old female was admitted to our hospital due to severe abdominal pain. A well-demarcated, oval shaped cystic tumor at the retropancreatic area with displacement of the pancreas and surrounding major vessels was observed on CT and MRI. Exploratory laparotomy was performed, and complete excision of the entire cyst was performed without complication. The pathologic finding was consistent with primary retropancreatic mucinous cystadenoma. To the best of our knowledge, this report is the first to describe a case of retropancreatic mucinous cystadenoma arising from the retropancreatic area in Korea.

Male Primary Retroperitoneal Mucinous Cystadenoma

Primary retroperitoneal mucinous cystadenoma of borderline malignancy is a rare disease, especially in male patients. Often these tumors are not incidentally found due to abdominal symptoms. We present the radiologic abdominal computed tomography scan, surgical, and pathologic images of this unique, rare condition in a male patient. Surgical treatment is recommended to establish diagnosis and treatment.

A male case of primary retroperitoneal mucinous cystadenoma: a diagnostic dilemma

We report a male case of primary retroperitoneal mucinous cystadenoma (PRMC) that was at initially misdiagnosed as a complicated renal cyst. On ultrasonography, a 71-year-old man was found to have an abdominal mass suspicious for right renal cyst. The initial computed tomography scan showed an unenhanced, low-density mass that deformed the edge of the right kidney into a beak shape. Four years later, the mass had increased in size. Magnetic resonance imaging revealed a cystic lesion. Its intracystic content showed relatively high intensity on a T1-weighted image, and the coronal gadolinium-enhanced T1-weighted image with fat suppression clearly showed a multilocular cystic mass without enhancing mural nodules. The final diagnosis of PRMC was obtained pathologically after surgery. Because PRMC has malignant potential, this rare entity should be considered when a retroperitoneal cystic tumor is evaluated, even in a male patient.

Primary retroperitoneal mucinous cystadenoma—A case study and review of the literature

INTRODUCTIONPrimary retroperitoneal tumours of mucinous type are extremely rare and can be further sub-divided into benign, borderline or cystadenocarcinoma. Prompt diagnosis of retroperitoneal tumours is important as the majority are malignant. PRESENTATION OF CASEOur case describes a 30year old woman, presenting with a 3month history of intermittent right iliac fossa pain. Abdominal examination demonstrated a mass palpable in the right iliac fossa. Ultrasonography of the abdomen demonstrated a cystic mass with a magnetic resonance imaging (MRI) scan of the pelvis further defining the lesion. Laparoscopy was performed to further evaluate and ultimately remove the retroperitoneal mass. Macroscopic and microscopic examination reported mucinous epithelium of endocervical type with no evidence of invasion. Findings were consistent with primary retroperitoneal mucinous cystadenoma. DISCUSSIONThis is the 19th reported case of a benign primary retroperitoneal mucinous cystadenoma in the English literature. The origin of mucinous cystadenomas in the retroperitoneum is widely debated with multiple theories suggested. Diagnosis of retroperitoneal tumours is important but difficult as serological investigations, ultrasonography, computed topography and magnetic resonance imaging, although useful, cannot allow a confident diagnosis. CONCLUSIONPrimary retroperitoneal mucinous cystadenoma is a benign tumour, however because of the malignant nature of the majority of mucinous retroperitoneal tumours they should be considered in the differential of chronic abdominal pain despite their rarity.

Primary retroperitoneal mucinous cystadenoma of borderline malignancy in a male patient. Case report and review of the literature

BackgroundPrimary retroperitoneal mucinous cystadenoma of borderline malignancy represents a rare tumor, with unclear histogenesis, concerning almost exclusively women. Only two cases concerning male patients have been reported.Case reportWe herein report a case of a 37 year old man undergone laparotomy for a sizable retroperitoneal tumor resulting after the histological examination to a primary retroperitoneal mucinous cystadenoma of borderline malignancy.ConclusionThis is the third case of primary retroperitoneal mucinous cystadenoma of borderline malignancy in a male patient reported in the literature. The preoperative diagnosis is impossible. Laparotomy constitutes the only diagnostic and curative approach.

Laparoscopic resection of primary retroperitoneal mucinous cystadenoma by retroperitoneal approach

International Journal of UrologyVolume 18, Issue 8 p. 607-608 Laparoscopic resection of primary retroperitoneal mucinous cystadenoma by retroperitoneal approach Kazutoshi Fujita M.D., Ph.D., Kazutoshi Fujita M.D., Ph.D. Department of Urology, Osaka General Medical Center, Osaka, Japan. kazufujita2@gmail.comSearch for more papers by this authorYoshiyuki Yamamoto M.D., Yoshiyuki Yamamoto M.D. Department of Urology, Osaka General Medical Center, Osaka, Japan. kazufujita2@gmail.comSearch for more papers by this authorSeiji Yamaguchi M.D., Ph.D., Seiji Yamaguchi M.D., Ph.D. Department of Urology, Osaka General Medical Center, Osaka, Japan. kazufujita2@gmail.comSearch for more papers by this author Kazutoshi Fujita M.D., Ph.D., Kazutoshi Fujita M.D., Ph.D. Department of Urology, Osaka General Medical Center, Osaka, Japan. kazufujita2@gmail.comSearch for more papers by this authorYoshiyuki Yamamoto M.D., Yoshiyuki Yamamoto M.D. Department of Urology, Osaka General Medical Center, Osaka, Japan. kazufujita2@gmail.comSearch for more papers by this authorSeiji Yamaguchi M.D., Ph.D., Seiji Yamaguchi M.D., Ph.D. Department of Urology, Osaka General Medical Center, Osaka, Japan. kazufujita2@gmail.comSearch for more papers by this author First published: 12 June 2011 https://doi.org/10.1111/j.1442-2042.2011.02799.xCitations: 7Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume18, Issue8August 2011Pages 607-608 RelatedInformation

Primary retroperitoneal mucinous cystadenoma with borderline malignancy in a male patient: a case report

IntroductionPrimary retroperitoneal mucinous cystadenoma is a rare tumor prevailing specifically in female gender. Its histogenesis is still unclear and its diagnosis is mainly based on morphological characteristics.Case presentationthe subject is a 44 years old man presenting an abdominal pain on the right side, with a palpable mass which appeared four months ago. Abdominal ultrasound (echography) revealed a retroperitoneal cystic process, which was successfully resected through laparotomy.Histopathological examination concluded to a mucinous cystadenoma with borderline malignancy foci.After a year of follow-up, no relapse was noticed in this patient.ConclusionRetroperitoneal mucinous cystadenoma is a rare tumor that should be considered in front of a retroperitoneal cystic process. Several hypotheses may explain the histogenesis of this pathological process.The interest in publishing this case report on primary retroperitoneal mucinous cystadenoma in a male patient lies in the rarity of occurrence of this syndrom in males as compared to females.

Primary retroperitoneal mucinous cystadenoma: Report of a case and review of the literature

Primary retroperitoneal mucinous cystadenomas (RMCs) are very rare and their biological behavior and histogenesis remain speculative. An accurate preoperative diagnosis of these tumors is difficult because no effective diagnostic measures have been established. We describe a 29-year-old woman with abdominal pain and a palpable mass. Computed tomography (CT) of the abdomen revealed a retroperitoneal cystic mass which was resected successfully at laparotomy. Histopathological examination of the resected mass confirmed the diagnosis of RMC. There was no evidence of disease 2 years after surgery.

Primary retroperitoneal mucinous cystadenoma with sarcoma-like mural nodule

Primary retroperitoneal cystadenomas are extremely rare. This is the first report in literature to describe a primary retroperitoneal cystadenoma with a sarcoma-like mural nodule. A 45-year-old woman complained of a left-sided abdominal mass. A computed tomography scan revealed a cystic mass with a mural nodule, which seemed to originate from the tail of the pancreas. At laparotomy the cyst was not adhered to the pancreas but localized retroperitoneally. Histologic examination showed a mucinous cystadenoma with only foci of borderline malignancy with a mural “sarcoma-like” nodule. In view of the surgical and histopathological findings, the mucinous cystadenoma was regarded as primary retroperitoneal. This case demonstrates that in the era of radiological preoperative refinement, pathological diagnosis remains of utmost importance, especially for rare cases.

Successful Removal of Primary Retroperitoneal Mucinous Cystadenoma by Laparoscopic Surgery

47세 여자 환자로 건강검진 시 초음파검사에서 우연히 발견된 약 5x3.5cm 크기의 후복막강 내 낭성 종물을 주소로 내원하였다. 문진에서 특별한 증상을 호소하지 않았으며, 이학적 검사에서 종물은 촉지되지 않았으며, 척추늑골각 압통은 없었으며, 다른 이상 소견은 없었다. 환자는 2회 임 신에 2회 자연분만의 출산력이 있었으며, 다른 내과적 질환 이나 외과적 수술력은 없었다. 전산화단층촬영에서 간밑오 목에 5x5x3.5cm 크기의 낭종이 관찰되었으며 내부는 균일 한 저음영으로 관찰되었고 오른쪽 신장 및 부신은 정상적 으로 관찰되었으며 간과도 명확한 경계를 가지고 있었다 (Fig. 1). 일반혈액검사 및 일반화학검사에서도 이상소견은 관찰되지 않았으며 종양 표지자 검사에서 CA 19-9은 11.4U/ ml (정상치 0-37U/ml), CA 125는 10.8U/ml (정상치 0-35U/ ml), CEA는 0.21ng/ml (정상치 0-5ng/ml), AFP은 1.95IU/ml (정상치 0-7IU/ml)로 모두 정상범주 내였다. 복강경적 적출술을 시행한 원발성 후복막강 점액성 낭성선종

A CASE OF RETROPERITONEAL MUCINOUS CYSTADENOMA OF BORDERLINE MALIGNANCY

A case of a primary retroperitoneal mucinous cystadenoma of borderline malignancy is presented. A 37-year-old female was found to have a retroperitoneal tumor associated with calcification by computed tomography. On laparotomy a cystic tumor in the retroperitoneum near the the left flank was found while the two normal ovaries were confirmed. The tumor was well encapsulated and 6.5×4.5×3.8cm in size. Its histological feature was mucinous cystadenoma of borderline malignancy by WHO classification. Retroperitoneal mucinous cystadenoma of borderline malignancy is so rare that only 12 cases including our case have been reported in the world. Clinical features and the prognosis are analized and appropriate surgical management of this disease is discussed.