Previous Editorial Research Articles

Reflecting on How Previous Academic Editors in Chief of JVIB Began Their Tenures as I Begin Mine

Reflecting on How Previous Academic Editors in Chief of <i>JVIB</i> Began Their Tenures as I Begin Mine

Reviewing Methods Contributions: From Current &amp; Previous Editors of Organizational Research Methods

Reviewing Methods Contributions: From Current &amp; Previous Editors of Organizational Research Methods

Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering

Mutations in amino acid sequences can provoke changes in protein function. Accurate and unsupervised prediction of mutation effects is critical in biotechnology and biomedicine, but remains a fundamental challenge. To resolve this challenge, here we present Protein Mutational Effect Predictor (ProMEP), a general and multiple sequence alignment-free method that enables zero-shot prediction of mutation effects. A multimodal deep representation learning model embedded in ProMEP was developed to comprehensively learn both sequence and structure contexts from ~160 million proteins. ProMEP achieves state-of-the-art performance in mutational effect prediction and accomplishes a tremendous improvement in speed, enabling efficient and intelligent protein engineering. Specifically, ProMEP accurately forecasts mutational consequences on the gene-editing enzymes TnpB and TadA, and successfully guides the development of high-performance gene-editing tools with their engineered variants. The gene-editing efficiency of a 5-site mutant of TnpB reaches up to 74.04% (vs 24.66% for the wild type); and the base editing tool developed on the basis of a TadA 15-site mutant (in addition to the A106V/D108N double mutation that renders deoxyadenosine deaminase activity to TadA) exhibits an A-to-G conversion frequency of up to 77.27% (vs 69.80% for ABE8e, a previous TadA-based adenine base editor) with significantly reduced bystander and off-target effects compared to ABE8e. ProMEP not only showcases superior performance in predicting mutational effects on proteins but also demonstrates a great capability to guide protein engineering. Therefore, ProMEP enables efficient exploration of the gigantic protein space and facilitates practical design of proteins, thereby advancing studies in biomedicine and synthetic biology.

EJEL Editorial 2024: The Allure of AI in Education

The objectives of this editorial are to provide a brief overview of the themes of EJEL papers published in 2023, compare these themes with the areas of work suggested in the previous Editorial (Charbonneau-Gowdy, et al., 2023), and propose new areas of focus for future research. The present Editorial will primarily concentrate on the main challenges arising from the release and use of GPT-3 and GPT-4 in 2023.

Australian Geomechanics – State of the Journal

It is my great pleasure and honour to introduce this issue of Australian Geomechanics. Following the resignation of previous Editor Bre-Anne Sainsbury, I offered to take on the Interim Editor role from the June 2023 issue to ensure continuity of the publication. The task duration has extended and based on the work completed to produce the latter three issues of the 2023 calendar year, this brief note presents some basic journal analytics, discusses current challenges facing Australian Geomechanics and aims to encourage the membership to prepare submissions for the benefit of the readership and the wider Australian geomechanics community. The sections about challenges and initiatives include references to discussions and brainstorming exercises held during my time at the AGS National Committee (2013-2019) and input from past Chairs and committee members during that period is acknowledged.

Epitaph for Timokritos Who Fell in Battle Against the Aetolians

The metrical inscription celebrates the death of the soldier Timocritus, who was killed in a clash with the Aetolians. Previous editors have unanimously dated the text to the end of the third century BCE, believing the war event to be related to one of the assaults the Aetolians made against Acarnania during the social war of 220‑217 BCE. A re-examination of the text and a comparison with other metrical epigraphs found on site and with historical sources allows an alternative dating proposal to be made. According to Livy, the polis of Tyrrheus was attacked again in 192‑191 BCE by the Etholos-Syriac troops of Antiochus III. In the absence of an autopsy examination or images of the find, it therefore seems plausible to ascribe the inscription either to the end of the third century BCE, linked to the events of the social war of 220‑217 BCE, or to the beginning of the second century BCE, connected to the Aetolo-Syrian attack of 192‑191 BCE.

The biggest brand in the dental market is the dental surgeon

Many still don't understand this new movement, which is not a "fad" but an established market trend, and belongs to the initial phase of this new era in which we live: the Age of Influence. In the previous editorial, we discussed the changing eras and their respective changes in market models.

Inaugural editorial.

The commencement of a new editorial tenure within the Journal of Personality and Social Psychology: Attitudes and Social Cognition (JPSP: ASC) provides an opportunity for reflection regarding the journal's core mission. The editors recognize that social psychology is at a crossroads due to competing demands that may have led to reduced submissions and posed challenges for previous editors in filling the journal's pages. Now, JPSP: ASC has been allotted more pages to allow for growth during this editorial term. Although this is desirable for the field, it adds to the pressure of identifying articles for publication given the difficulties filling the pages during previous editorial terms. As the premier outlet of social psychology since 1965, JPSP: ASC will retain its centrality if we increase submissions and publish more articles, while continuing to strive to communicate methodologically trustworthy, intellectually stimulating, and socially relevant research, in a responsible fashion. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Critical Notes on Pseudo-Sisbert’s Exhortatio Poenitendi

This paper discusses textual problems in an anonymous Late Latin poem entitled Exhortatio poenitendi. In his classic edition (Berlin 1914), Karl Strecker used nine witnesses. In my critical edition from 2021, I studied, collated, and classified twenty manuscripts of this poem and established a new stemma codicum; a manuscript not known to me at the time has been used in this paper. In this article I propose new conjectures absent from my edition, reject other proposals made by previous editors, and discuss lines in which either the stemma cannot be used to guide the editor in the choice of readings, the diffusion of variants is irregular, or I have made a choice different from that of previous editors. Many of the disputed passages can now be clarified in the light of two other works attributed to the same anonymous author (the Lamentum poenitentiae and the Oratio pro correptione uitae), which were published together with the Exhortatio poenitendi for the first time in my 2021 edition.

Best Practice Recommendation Updates 2024: Methodology For Developing Foundations Of Best Practice For Skin and Wound Management

The Best Practice Recommendations are the most popular resource developed by Wounds Canada and are used by frontline clinicians, students and policy makers to inform their practice. The Best Practice Recommendation Updates 2024 build on the work of previous authors and editorial teams and incorporate expert opinion, clinical experience and the latest available research. This article summarizes the methodology used in the development of the Recommendations.

The Need to Use Different Ways of Applying Pesticides

In a previous Editorial, the emphasis was on the need to adopt Integrated Pest Management (IPM), but for the majority of farmers, there is the need to spray a pesticide, which hopefully will increasingly be a biopesticide, but to control certain pests, a chemical pesticide may still be required. The need to control a disease, downy mildew (Peronospora viticola) on some grape seedlings from America was detected by Millardet in France back in 1878. The disease was not adequately controlled using sulphur, but after a farmer sprinkled some water, containing copper sulphate to deter children and travellers along the highways picking the grapes, Millar det developed a mixture of copper sulphate and lime as a fungicide that was named Bordeaux Mixture, which he tested on the foliage and the mildew. According to Lodeman (1896) the first systematic applications of copper sulphate, mixed with lime were in about 1884, when it was decided that this was the most promising of all the various mixtures that had been tried. The recipe was dissolving 8 kilos of commercial copper sulphate in 100 litres of water. In another container 15 kilos of quicklime were mixed in 30 litres of water. This was then mixed with the copper sulphate and stirred well and then some was taken in a pail and sprinkled using a small broom on the vine foliage. Interestingly, Millardet thought that in the case of severe rains, it might be advisable to make a second application.

Welcome to the New Issue (Vol: 29, No: 3, 2023) and Current News of the European Journal of Therapeutics

Welcome to the New Issue (Vol: 29, No: 3, 2023) and Current News of the European Journal of Therapeutics

Publication bias, statistical power and reporting practices in the Journal of Sports Sciences: potential barriers to replicability

ABSTRACTTwo factors that decrease the replicability of studies in the scientific literature are publication bias and studies with underpowered desgins. One way to ensure that studies have adequate statistical power to detect the effect size of interest is by conducting a-priori power analyses. Yet, a previous editorial published in the Journal of Sports Sciences reported a median sample size of 19 and the scarce usage of a-priori power analyses. We meta-analysed 89 studies from the same journal to assess the presence and extent of publication bias, as well as the average statistical power, by conducting a z-curve analysis. In a larger sample of 174 studies, we also examined a) the usage, reporting practices and reproducibility of a-priori power analyses; and b) the prevalence of reporting practices of t-statistic or F-ratio, degrees of freedom, exact p-values, effect sizes and confidence intervals. Our results indicate that there was some indication of publication bias and the average observed power was low (53% for significant and non-significant findings and 61% for only significant findings). Finally, the usage and reporting practices of a-priori power analyses as well as statistical results including test statistics, effect sizes and confidence intervals were suboptimal.

Turgot’s missing manuscripts – partially recovered

Since 2015 it has become clear that various manuscripts that once belonged to the Turgot family archive are missing. This paper reports on the recent recovery in Japan of photographs of some of these manuscripts and presents a case study of the images of the famous draft known as Valeurs et monnaies. It allows one to appreciate the practices of previous editors of Turgot’s writings as well as the writing process of the author.

News from the European Journal of Therapeutics: A new issue and a new editorial board

News from the European Journal of Therapeutics: A new issue and a new editorial board

Introduction: Hear From Our New Editor

I would like to welcome all readers to the April 2023 issue of Frontiers: The Interdisciplinary Journal of Study Abroad. While this is technically my first issue as Editor, all credit for the excellent content in it goes to the previous editor, Dr. Audrey Murrell, as well as to the ongoing Managing Editor Dr. Amelia Dietrich and our Editorial Assistant Anas Almassri. I am delighted to be onboard as of January and to be working now on the November issue.

Editor’s Choice Articles for April

Editor’s Choice Articles for April

Greetings From the New Editor

As I begin my term (January 2023–December 2027) as Editor-in-Chief of the ASME Journal of Mechanical Design, I would like to offer a few thoughts on the current state of the journal and the many opportunities for growth in the coming years. I am truly honored and humbled to continue the tradition of excellence established by previous editors—Professors Michael McCarthy (University of California, Irvine) (2003–2007), Panos Papalambros (University of Michigan) (2008–2012), Shapour Azarm (University of Maryland) (2013–2017), and Wei Chen (Northwestern University) (2018–2022)—whose vision, hard work, and dedication built JMD into one of the leading journals in our field.Over the past five years, my predecessor, Professor Wei Chen, has worked tirelessly on a number of impactful initiatives, for which the JMD community is truly grateful. The journal’s impact factor has risen to 3.441 (2021), and the average time elapsed from submission to editor decision has decreased to less than 1.5 months, making it one of the leading journals in the ASME portfolio. JMD has begun hosting quarterly webinars to highlight timely topics and encourage in-depth discussion of emerging research threads. Under Professor Chen’s leadership, JMD expanded the publication of special issues to highlight strategic, emerging research themes, including a new annual special issue that fast tracks some of the most highly reviewed papers from the ASME IDETC conference. JMD’s companion website1 has continued to thrive, hosting featured articles and serving as an important repository and bulletin board for all aspects of the journal. Professor Chen also implemented several initiatives to enhance inclusivity, including a double-blind review process, an increasingly diverse cohort of associate and guest editors (with more than 30% of AEs identifying as women or members of underrepresented groups), a DEI advocate, and special efforts to encourage participation from international and underrepresented members of the community.Over the next five years, I would like to build on these initiatives and grow the journal community in several ways. While it will take some time to become completely familiar with all of the facets of the journal, I’ve identified a few focus areas as a starting point. First, I would like to build an advisory board, separate from the suite of associate editors and populated with former associate editors and other scholars who are passionate about JMD, to help us catalyze some new initiatives. One example is an expanded view of inclusivity to include not only underrepresented populations but also new authors and early career members of the community. Work is needed to amplify their voices and demystify and support the process of successfully publishing a paper in JMD as a new author. Another initiative is a concerted effort to publish broad, insightful reviews of the status of research in the mechanical design community, the impact of our research, and the challenges facing the community. If our work is successful, these reviews will serve as required reading for incoming graduate students and scholars, much as the Finger and Dixon reviews educated previous generations. Together with the advisory board and the associate editors, I would like to host roundtable discussions at major conferences, such as IDETC and ICED, to seek feedback and suggestions from the community. Finally, we will strive to continue the efforts of previous editors to raise the impact factor and decrease the time for review while simultaneously emphasizing the need for a fair and thoughtful review process.None of these things would be possible without an exceptional collection of Associate Editors, reviewers, and authors, and one of the most superb assistants in publishing, Ms. Amy Suski. I’m also grateful for the exceptional behind-the-scenes efforts of our featured articles editor and webinar organizer, Professor Faez Ahmed, and my co-editor, Professor Qiaode Jeff Ge, who handles all of the mechanism-related submissions. Their dedication and hard work are an invaluable contribution to the community, and I am humbled to work with them every day.Please continue to support the journal by sending us your very best papers, contributing thoughtful and constructive reviews, and contacting me any time with ideas for improving the journal or leveraging the journal platform to support the community in meaningful ways. The mechanical design community has always been a warm and welcoming professional home for me, so it’s an incredible privilege to work with all of you to raise our journal to the next level of excellence.

Frankenstein’s Journal: Introducing the Reanimated University of Western Ontario Journal of Anthropology

This special issue of The University of Western Ontario Journal of Anthropology (UWOJA) serves to relaunch the journal after a prolonged hiatus. UWOJA (formerly TOTEM) published its first volume in 1994 and in its life, has endeavored to publish exceptional pieces of creative and original research by undergraduate and graduate students in all four subfields of anthropology. Despite UWOJA’s interruption in publication (2016-2023), the journal has had a considerable impact, especially for a student-led journal, receiving nearly 600 citations across 151 articles and becoming one of the most-consulted resources on Scholarship@Western. As of January 2023, articles from UWOJA have received over 35 thousand downloads. In addition to its contributions to anthropological knowledge, UWOJA has provided opportunities for many undergraduate and graduate students to participate in the peer-review and journal publication processes. In this issue, UWOJA’s new Editorial Committee intends to highlight the collective effort of previous authors, reviewers, editors, and organizational committees by republishing a selection of the most highly cited, or currently relevant, articles from the journal’s nearly 30-year history and discussing the impact these opportunities have had on the authors’ careers. Just as Frankenstein’s creature was brought to life using a collection of repurposed parts, this issue reanimates UWOJA by compiling highlights from its past.

2023 Eberhard F. Mammen Award Announcements: Part I-Most Popular Articles.

Welcome to the latest of our Eberhard F. Mammen award announcements. As noted in previous editorials ([Table 1]), Thieme, the publisher of Seminars in Thrombosis and Hemostasis (STH), has created the “Eberhard F. Mammen Excellence in Thrombosis and Hemostasis Awards” in honor of Eberhard Mammen ([Fig. 1]), and in recognition of his contribution to this field and to the journal that he both founded and steered for over three decades. These awards began in 2009, under two categories, “Most Popular Article Awards” and “Young Investigator Awards.” Accordingly, 2023 represents 15 years of award presentations ([Table 1]). Current details and conditions of the award can be summarized as: