A 50-year-old Indigenous female, on home haemodialysis, was found to have a large mycotic aneurysm of the proximal left anterior descending coronary artery at the site of a previous drug eluting stent. Blood cultures grew methicillin sensitive Staphylococcus aureus bacteria. She underwent a complex operation involving resection of the mycotic aneurysm, removal of the stent and a coronary artery bypass graft to the distal LAD using the left internal mammary artery. She had a complicated ICU admission with pericardial tamponade on day one post-operatively requiring reopening and removal of clot and type 1 respiratory failure requiring re-intubation on day 10 post-operatively. Once extubated, she developed prolonged hyperactive delirium and significant decline in mobility. Over the course of a six-week hospital admission, she received extensive multidisciplinary care and was discharged for rehabilitation to a peripheral hospital. She made a remarkable recovery and was discharged home after rehabilitation with ongoing follow up with infectious diseases.