Prevention Methods Research Articles

Chitosan Phytate Nanoparticles: A Synergistic Strategy for Effective Dental Caries Prevention.

Dental caries is a widespread oral disease that poses a significant medical challenge. Traditional caries prevention methods, primarily the application of fluoride, often fall short in effectively destroying biofilms and preventing enamel demineralization, thereby providing limited efficacy in halting the progression of caries over time. To address this issue, we have developed a green and cost-effective synergistic strategy for the prevention of dental caries. By combining natural sodium phytate and chitosan, we have created chitosan-sodium phytate nanoparticles that offer both the antimicrobial properties of chitosan and the enamel demineralization-inhibiting capabilities of sodium phytate. In an ex vivo biofilm model of human teeth, we found that these nanoparticles effectively prevent biofilm buildup and acid damage to the mineralized tissue. Additionally, topical treatment of dental caries in rodent models has shown that these nanoparticles effectively suppress disease progression without negatively impacting oral microbiota diversity or causing harm to the gingival-mucosal tissues, unlike traditional prevention methods.

The prevention effect of Limosilactobacillus reuteri on acute kidney injury by regulating gut microbiota.

Acute kidney injury (AKI) has considerably high morbidity and mortality but we do not have proper treatment for it. There is an urgent need to develop new prevention or treatment methods. Gut microbiota has a close connection with renal diseases and has become the new therapy target for AKI. In this study, we found the oral administration of the probiotic Limosilactobacillus reuteri had a prevention effect on the AKI induced by lipopolysaccharide (LPS). It reduced serum concentration of creatinine and urea nitrogen and protected the renal cells from necrosis and apoptosis. Meanwhile, L. reuteri improved the gut barrier function, which is destroyed in AKI, and modulated the gut microbiota and relevant metabolites. Compared with the LPS group, L. reuteri increased the proportion of Proteobacteria and reduced the proportion of Firmicutes, changing the overall structure of the gut microbiota. It also influenced the fecal metabolites and changed the metabolite pathways, such as tyrosine metabolism, pentose and glucuronate interconversions, galactose metabolism, purine metabolism, and insulin resistance. These results showed thatL. reuteri is a potential therapy for AKI as it helps in sustaining the gut barrier integrity and modulating gut microbiota and related metabolites.

Hot spots and trends in microbial disease research on cultural heritage: a bibliometric analysis.

This study is to understand and analyze the development history, research hotspots, and research trends in the study of microbial diseases of cultural heritage through bibliometric analyses in order to fill the current gap of no literature review in this research field and to make certain contributions to the research in this field and the protection of cultural heritage. Bibliometric and visual analyses of the literature on cultural heritage microbial diseases in the Web of Science (WoS) core collection were carried out using VOSviewer and R-bibliometrix, choosing the two main literature types of papers and reviews. The emphasis was placed on analyzing and summarizing core research strengths, hotspots, and trends. Six hundred sixty-seven documents (573 articles and 94 reviews) were retrieved. αIn the WoS core collection, the first literature on cultural heritage microbial disease research was published in January 2000, and the annual number of publications from 2000 to 2009 did not exceed one; the annual number of publications from 2010 onwards increased rapidly, and after 2018, the number of publications per year exceeded 60, reaching 94 in 2020, which indicates that cultural heritage microbial disease research is booming. Our research showed that Italy, the USA, and China were the leading research countries, and Univ Milan was the institution with the most publications. International Biodeterioration &Biodegradation was the most published and co-cited journal, and Gu JD was the most prolific author. The research hotspots in the study of microbial diseases of cultural heritage mainly include biological degradation of cultural heritage; identification of diseased microorganisms and disease mechanisms; cultural heritage microbial disease prevention and control methods; monitoring, prevention, and control of diseased microorganisms in indoor air; antibacterial agents, especially essential oils, nanoparticles, and other safe and efficient antibacterial products research and development; and exploration of the mechanisms of biofilm protection of cultural heritage on cultural heritage surfaces. Monitoring and identifying cultural heritage microbial communities, identifying disease mechanisms, and researching safe and efficient bacteriostatic products such as essential oils and nanoparticles will be the main research directions in the field of cultural heritage microbial disease prevention and control in the future.

Outdoor workers' perceptions of skin cancer prevention: a qualitative study.

Outdoor workers are at increased risk for skin cancer and melanoma. This qualitative study aimed to explore outdoor workers' perspectives and experiences of primary (i.e. sun protection) and secondary prevention, i.e. skin self-examination (SSE) of skin cancer. Purposive, snowball, and theoretical sampling was used to recruit outdoor workers in Kentucky and Indiana. Semi-structured interviews via telephone or videoconference of approximately 45min were conducted with interviewer probes and questions about perceptions of cancer risk, prevention, and screening techniques conducted, perceived barriers and facilitators, and preferences for health dissemination venues. The recordings were transcribed verbatim and de-identified. Analysis involved constructivist grounded theory coding strategies. Using peer debriefing and consensus building around themes, the researcher established a codebook for all interviews to utilize within Dedoose software for systematizing and organizing data. Eighteen interviews were conducted. Interviewees (N = 18) ranged in age from 35 to 78 yr, with 3 females. Outdoor industries included agriculture, maintenance, and grounds maintenance. Themes derived from the data showed the underlying factors and perceptions that influence outdoor workers to conduct primary and secondary cancer prevention activities. The level of alarm attributed to disease and the level of trust in information contribute to intentions to conduct activities. The intentions and trust toward healthcare institutions and providers drive the primary or secondary prevention behaviors. Cultural and contextual factors included masculinity and self-sufficiency, familial and occupational priorities, and community ties. These data provide a basis for developing future communications and interventions to decrease skin cancer incidence in outdoor workers. They indicate that secondary prevention and building self-efficacy in conducting SSE should be emphasized in tandem or over primary skin cancer prevention methods in this population. Trusted local healthcare providers should primarily provide prevention information, and materials should utilize testimonials from the local community to best influence this population. Communications and training interventions are needed in this population to induce a proactive level of alarm about cancer and result in the performance of SSE.

A Non-Intrusive Method for Lonely Death Prevention Using Occupancy Detection and an Anomaly Detection Model

In countries like Japan, Australia, France, Denmark, and South Korea, the numbers of single-person households and older adults living alone have been steadily increasing each year, leading to the social issue of lonely deaths among older adults. Against this backdrop, this study proposes a method to develop a system for preventing lonely deaths based on information technology, including the Internet of Things (IoT). IoT sensor data, which include nine environmental variables such as indoor temperature, relative humidity, CO2 concentration, fine dust particle levels, illuminance, total volatile organic compound levels, and occupancy data collected from passive infrared sensors, provide empirical evidence so that anomalies can be detected in the behavior patterns of older adults when they remain in one place for an unusually long time. Detecting such risky situations for older adults living alone involves anomaly detection through occupancy monitoring. The data from occupancy monitoring were analyzed using four classification models, namely Logistic Regression, k-Nearest Neighbor, Decision Tree, and Random Forest, with the performance of occupancy detection being compared across these models. Furthermore, the method proposed in this study includes data processing for environmental variables to improve the performance of occupancy detection.

Identification of potential biomarkers of leprosy: A study based on GEO datasets.

Leprosy has a high rate of cripplehood and lacks available early effective diagnosis methods for prevention and treatment, thus novel effective molecule markers are urgently required. In this study, we conducted bioinformatics analysis with leprosy and normal samples acquired from the GEO database(GSE84893, GSE74481, GSE17763, GSE16844 and GSE443). Through WGCNA analysis, 85 hub genes were screened(GS > 0.7 and MM > 0.8). Through DEG analysis, 82 up-regulated and 3 down-regulated genes were screened(|Log2FC| > 3 and FDR < 0.05). Then 49 intersection genes were considered as crucial and subjected to GO annotation, KEGG pathway and PPI analysis to determine the biological significance in the pathogenesis of leprosy. Finally, we identified a gene-pathway network, suggesting ITK, CD48, IL2RG, CCR5, FGR, JAK3, STAT1, LCK, PTPRC, CXCR4 can be used as biomarkers and these genes are active in 6 immune system pathways, including Chemokine signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Natural killer cell mediated cytotoxicity and Leukocyte transendothelial migration. We identified 10 crucial gene markers and related important pathways that acted as essential components in the etiology of leprosy. Our study provides potential targets for diagnostic biomarkers and therapy of leprosy.

Goiter Prevalence and Associated Factors among Women in Hargeisa, Somalila

Background: Goiter, which is associated with various risk factors, is highly prevalent in Hargeisa region of Somalia and is a serious health problem among women living in the region.Objective: This study aims to reveal the true extent of the problem, identify the causative factors and suggest preventive methods accordingly.Methods: A cross-sectional analysis was conducted on 270 female patients randomly selected from 1659 patients at Hargeisa Group Hospital (HGH), in Somalia, between January and August of 2022. The study sample was equally distributed between those with and without a diagnosis of goiter. Independent risk factors were identified by making comparisons between groups.Results: For the study group, dietary habits were identified as an important risk factor for the development of goiter. Patients who regularly consumed ‘cabbage’ - 188 (87.4%) had a higher rate of goiter compared to those who did not - 64 (47.4%); (p&lt;0.001). Furthermore, those who consumed iodized salt regularly or more frequently - 54 (40%) were less likely to have goiter compared to those who did not - 128 (94.8%); (p&lt;0.001). The use of non-iodized salt and cabbage consumption were identified as predictive factors for the development of goiter.Conclusion: Randomized studies with larger study groups should be conducted. The Minister of Health, health professionals and the media should work in cooperation to raise public awareness and take necessary precautions.International Journal of Human and Health Sciences Vol. 08 No. 02 Apr’24 Page: 192-197

Evaluation of the dynamics of oral pathogenic microbiota in COVID-19 patients by genomic sequencing after application of foam with antimicrobial action

Relevance. The COVID-19 pandemic caused by the SARS-CoV-2 virus has demonstrated the critical importance of understanding the mechanisms of transmission and finding effective methods of prevention. Particular attention has been paid to the role of oral hygiene, as the oral cavity serves as a major route of transmission. Studies show that the composition of the oral microbiota can influence the course and outcome of COVID-19 disease. Therefore, there is a need to study the effects of oral antiseptics on the microbiome, which may offer new opportunities for the prevention and treatment of this disease.Objective. The aim of this study is to evaluate the effectiveness of the oral cleansing foam «Parodontol PROF» in reducing the pathogenic microflora of the oral cavity in patients with COVID-19 and to assess its effect on the risk of secondary infections.Materials and methods. The study was conducted on the basis of the Clinical Medical Centre «Kuskovo» of Russian University of Medicine. It included 450 patients with a confirmed diagnosis of COVID-19. The participants were divided into two groups: the test group used oral cleansing foam, while the control group used no additional oral hygiene. Comparative analyses of the taxonomic composition of the oropharyngeal microbiota and dental plaque before and after the use of the cleansing foam were performed.Results. The study showed that patients who regularly used the cleansing foam «Parodontol PROF» had a significant decrease in the representation of pathogens, including Mycoplasma, and an increase in the number of beneficial commensals such as Lactococcus and Lactobacillus. These changes indicate the potential efficacy of this product to improve oral hygiene and reduce the risk of secondary infections.Conclusion. The study supports the hypothesis that improving oral hygiene with specialised antiseptic agents, such as a cleansing foam, may help to reduce pathogenic microflora in the oral cavity in patients with COVID-19. This, in turn, may reduce the risk of pathogen migration into the lower respiratory tract and the development of secondary infections. The findings emphasise the importance of further research in this area and the development of comprehensive approaches to oral hygiene management in the context of infectious diseases.

Modern concepts about cyclic vomiting syndrome in children

Despite the relatively low prevalence in the world and in Russia, in particular, of such a pathology as cyclic vomiting syndrome, the relevance of the problem is due to the lack of research and sufficient information about the etiology, pathogenesis, and most importantly about methods of treatment and prevention of the disease. This syndrome is typical for children aged 3 to 7 years and is manifested by repeated stereotypical episodes of vomiting, alternating with periods of complete well-being. Cyclic vomiting syndrome worsens the child’s quality of life and seriously affects their further development and socialization. The article provides an overview of scientific research on cyclic vomiting syndrome in children.

КЛИНОВИДНЫЕ ДЕФЕКТЫ ЗУБОВ

Non-carious lesions are common diseases encountered by dentists. One of these diseases manifests itself in the form of a wedge-shaped defect in dental tissue. It is a lesion of tooth enamel of non-carious origin in the cervical area. This disease is easy to detect during the initial examination, since the tooth defect is wedge-shaped [1]. It is important to note that the pathology can have varying degrees of severity, from small depressions to more serious damage. The defect got its name due to the wedge-shaped shape of the lesion. Most often, a wedge-shaped defect appears in premolars or canines. It can affect both the upper and lower sides of the jaw. Research shows that the number of patients with this pathology is increasing every year. According to some authors, the prevalence of wedge-shaped dental defects among the population of the Russian Federation is up to 34% [4]. Many scientists attribute this to improper use of hygiene products and excessive consumption of acidic foods. Recent studies also indicate a connection between the development of wedge-shaped defects and dental overload caused by psycho-emotional tension and stress [3, 5]. This lesion not only affects the aesthetic appearance of the smile, but can also cause increased tooth sensitivity [2]. Scientists have not yet reached a consensus on treatment methods, but in many cases the disease can be prevented using simple preventative methods.

Contraceptive strategies for reducing the risk of reproductive cancers.

Reproductive cancers, encompassing various malignancies like endometrial, ovarian, cervical cancer, and gestational trophoblastic neoplasia, pose a significant global health burden. Understanding their patterns is vital for effective prevention and management. Contraceptives show a protective effect against some of these cancers. This clinical guidance document aims to elucidate the disease burden of reproductive cancers and the evidence supporting contraceptive methods in prevention and management. Regional disparities in incidence and mortality highlight the urgent need for targeted interventions, particularly in low-resource settings. Healthcare providers must weigh individual risk profiles and medical eligibility criteria when discussing contraceptive options. Enhanced health literacy through direct patient education is essential for leveraging low-cost behavioral interventions to mitigate reproductive cancer risks.

Out of hospital sudden cardiac arrest as a prognostic factor for in-hospital mortality in patients admitted with cardiogenic shock

Abstract Funding Acknowledgements None. Background The mortality in cardiogenic shock (CS) is still high despite new comprehensive therapies. Cardiac arrest (CA) frequently complicates CS which can have an unfavourable effect on the course after admission. Purpose The study aimed to analyse the clinical characteristics and prognosis of patients admitted with CS after out-of-hospital cardiac arrest (OHCA) compared to the group without OHCA. Methods The studied group consisted of a total of 80 patients with an average age of 62 ± 13 years (81 % male) admitted to tertiary hospital with CS in the period 2021-2022. The severity of the shock according to the Society for Cardiac Angiography and Interventions (SCAI) SHOCK classification among the whole population was from C to E: 7 (9%), 38 (48%), and 35 (43%), respectively. The cohort was divided into 2 subgroups: the OHCA group consisted of 23 individuals (29%) and the without OHCA (non-OHCA group) consisted of 57 individuals. Results The groups did not differ in terms of demographic parameters and comorbidities. There were no differences in baseline heart rate 95 [50;114] vs. 91 [77;105] beats per minute and mean artery pressure 75 [70;97] vs. 82 [70;97] mmHg for OHCA vs. non-OHCA, respectively, all p&amp;gt; 0.05. Patients from OHCA group had higher baseline creatinine level 1.65 [1.35;1.88] vs. 1.37 [1.08; 1.65] mg/dL, p=0.019, white blood cell count 12 [9;16] vs. 17 [12;23] × 109/L, p=0.015 and lower pH from blood gas analysis 7.0 [6.9;7.2] vs. 7.3 [7.2;7.4], p&amp;lt;0.001). In the OHCA group, 90% of cases of CS were caused by acute coronary syndrome (ACS), while in the group without OHCA, 76% were due to ACS and 20 % due to the progression of chronic heart failure, p=0.032. Mechanical Circulatory Support (MCS) was used in almost every patient (98% non-OHCA vs. 95% OHCA), however, the OHCA group was more often treated with V-A ECMO 14 (64%) vs. 16 (28%) in the non-OHCA, p=0.004. The overall number of in-hospital deaths was 57 (71%). The OHCA group had significantly higher in-hospital mortality 22 (96%) compared to the non-OHCA patients 35 (61%), p=0.002. Conclusion Patients experiencing CS complicated by OHCA have more often ischaemic ethology of shock, have a greater degree of organ damage and a lower pH in blood gas analysis at admission, and have extremely high in-hospital mortality rates when compared with patients facing CS but without prior OHCA, which underscores the urgent need for improved prevention methods, interventions, and public awareness.

Postharvest disease, latent infection, and preharvest control of ‘Shine-Muscat’ grapes

The cultivation of ‘Shine-Muscat’ grape variety is rapidly expanding in East Asia due to its exceptional qualities favored by consumers. However, studies on the disease pathogens affecting this variety and how to control them remain limited. This study focuses on investigating postharvest diseases that impact ‘Shine-Muscat’ grapes and explores potential prevention methods, with regional emphasis on Shanghai metropolitan area, a key market for edible grapes in China. Common market diseases such as Alternaria spot, grey mold, and Aspergillus rot are frequently found in ‘Shine-Muscat’ grapes, accounting for 29.2%, 20.4%, and 16.7% of diagnostic cases, respectively. The study revealed that Alternaria spp., Cladosporium spp., and Botrytis cinerea could attach to or invade grape fruits during the flowering, young fruit, and veraison stages of ‘Shine-Muscat’. In contrast to conventional open field cultivation methods, the rain-shelter and root restriction cultivation can aid in reducing fruit disease incidence during production, and thus alleviate the postharvest disease risks. Moreover, the application of calcium propionate during fruit development stages could efficiently manage both in-field and post-harvest diseases, and extend storage life of harvested fruit.

COMORBIDITY IN ONCOLOGY: MODERN CHALLENGES AND THE SEARCH FOR WAYS TO SOLVE THE PROBLEM

Introduction. The article is devoted to the current problem of modern oncology – increasing the treatment effectiveness of cancer patients with comorbidities. Comorbidity is accompanied by higher rates of mortality, disability, side effects of treatment, increased use of the patient's body resources, and lower quality of life. The aim of the study. To develop a method of recurrence prevention after bone lesions resection and bone replacement surgery for malignant primary bone tumors, which would ensure a longer duration of the 1st recurrence-free period in patients with comorbidities. Materials and methods. The study included a control group consisting of 27 patients who underwent bone replacement surgery after removal of primary malignant tumors of the pelvis and lower extremities. The study group included 25 patients who underwent biomin bone replacement surgery after removal of malignant primary tumors of the pelvic bones and lower limbs, as well as neuropeptide therapy with the drug dalargin. Results. The obtained data testify to the effectiveness of the proposed method of treatment with the use of dalargin: compaction of the structure of compact and spongy tissues and an increase in their heterogeneity have been established. Under the influence of dalargin, the structure of the interface, characteristic of intact bone tissue, is reorganized, accordingly, the restoration of strength is observed. 12 months after the operation, the bone density in the patients of the main group practically recovered to the values typical for the intact limb (p&lt;0.01). No such recovery was observed in patients of the control group. Within 11 to 23 months, 10 patients of the control group had tumor recurrences. Instead, in the study group, the analysis of the results revealed the following: within 21 months, only 1 patient had a recurrence of the tumor. Conclusions. Neuropeptide Dalargin helps to increase the duration of the 1st relapse-free period in patients with primary malignant bone tumors with polymorbidity. The proposed treatment method with integration into the therapeutic protocol of the neuropeptide dalargin allows to increase the complex therapy effectiveness and improve the prognosis of the course of the disease.

Precise Control and Prevention Methods for Whitefly in Greenhouse Vegetables

Trialeurodes vaporariorum Westwood (greenhouse whitefly) are worldwide polyphagous pests of economic importance that damage solanaceous vegetables. Neonicotinoid pesticides and parasitoid Encarsia formmosa Gahan are the main management strategies applied worldwide, but precise control methods in greenhouse vegetables need to be developed to reduce the application amounts of pesticides and improve the suppression of whitefly populations. Therefore, we assessed the indoor acute toxicities and risk assessment of neonicotinoids for T. vaporariorum and E. formosa adults and pupae and compared the control effects of E. formosa and neonicotinoid acetamiprid. According to the acute toxicities results, most neonicotinoid insecticides were more toxic to E. formosa than T. vaporariorum, and pupae were much less susceptible than adults of both species. Moreover, acetamiprid had a low risk effect on E. formosa. Sole application of E. formosa and acetamiprid could effectively control T. vaporariorum, but their combined application resulted in antagonistic effects on the control of T. vaporariorum. The results showed that a combined application or sole use of E. formosa could reduce the use of insecticides, slow down the development of insecticide resistance in whiteflies, and improve the efficiency of controlling the growth of whitefly populations in greenhouse vegetable production.

Intraoperative Hypertonic Saline Irrigation Preventing Seroma Formation in the Treatment of Axillary Bromhidrosis.

Subcutaneous seroma formation (SF) is commonly seen after axillary bromhidrosis surgeries and its treatment can be challenging and long. Current prevention methods are not consistent, and the treatment includes repeated aspirations and drains, both are associated with higher risk for infections. The purpose of this article is to present a novel and simple technique of intraoperative hypertonic saline irrigation (IHSI) to axillary bromhidrosis subcutaneous dead space, which prevents postoperative SF and enables early drain removal due to reduced secretions. From 2015 to 2022, we performed the intraoperative irrigation of the cavity through normal saline in 100 patients with primary axillary bromhidrosis. Through an incision approximately 3 cm long at the central axillary crease, the entire subcutaneous tissues containing apocrine glands were initially dissected with straight scissors within the axillary area, and then, the undermined apocrine glands were removed with curved scissors. The skin was defatted to become a full-thickness skin flap. Any suspected hemorrhagic spots were immediately coagulated electrosurgically. Negative pressure drains were placed, and intraoperative irrigation of the cavity through the drains with 20 ml of NaCl 0.9% or NaCl 10% left at site for 10 min applies different saline solutions in the same patients. The volumeofdrainage on the 1st postoperative day was 6.54±0.36 mL for the group B, which was significantly less than 15.23±0.42 mL for the group A (p < 0.05). The time of drain removal for the group B was 24 h, which was shorter than 48 h for the group A. In group B, 4 percent of axillae showed significant SF postoperatively, which was lower than the 20 percent of axillae associated with the group A (p < 0.05). The rate of incision infection for the group B was 2 percent, which was significantly lower than the 6 percent of axillae in the group A (p < 0.05). Two percent of axillae showed skin edge necrosis postoperatively in the group B, which was lower than the 10 percent of axillae associated with the group A (p < 0.05). IHSI enhances adhesion formation and reduces secretion rate in subcutaneous dissection space after axillary bromhidrosis surgeries, therefore enables early drain removal and prevents SF, incision infection and skin edge necrosis. As a result, reducing the pain of patients, decreasing inconveniency and cost saving of multiple outpatient visits or additional surgery. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

A qualitative look at bed net access and use in Burkina Faso, Mozambique, Nigeria, and Rwanda following piloted distributions of dual-active ingredient insecticide-treated nets

BackgroundUniversal coverage with insecticide-treated nets (ITNs) is important for malaria control and elimination. The emergence and intensification of insecticide resistance threatens progress made through the deployment of these interventions and has required the development of newer, more expensive ITN types. Understanding malaria prevention behaviour, including barriers and facilitators to net access and use, can support effective decision-making for the promotion and distribution of ITNs.MethodsIn-depth interviews and focus group discussions were conducted in 3 to 4 villages per district, in 13 districts across Burkina Faso, Mozambique, Nigeria and Rwanda from 2019 to 2022. Interviews were conducted in the local language, translated and transcribed in English, French or Portuguese. Transcripts were coded and analysed using Nvivo and ATLAS.ti.ResultsITNs were obtained from mass distribution campaigns, antenatal care and immunization visits, and purchased on the private market in some locations. While there were divergent perspectives in whether the number of distributed nets were adequate, participants consistently expressed concerns of bias, discrimination, and a lack of transparency with the distribution process. ITNs were frequently used alongside other malaria prevention methods. The primary motivation for use was malaria prevention. While some participants reported using nets nightly throughout the year, other participants reported seasonal use, both due to the perceived higher density of mosquitoes and discomfort of sleeping under a net in the increased heat. Other barriers to consistent net use included activities that take place away from the home, sleeping patterns and arrangements, and sensitivity to the insecticides on the nets.ConclusionsITNs remain an important malaria control intervention. To ensure adequate and increased net access, distribution campaigns should consider family structures, available sleeping spaces, and other bed sharing preferences when identifying the number of nets needed for distribution. In addition, campaigns should allow for multiple options for net distribution points and timing to accommodate households remote to health services. Continuous distribution channels and complimentary distribution through the private sector could help fill gaps in coverage. Solutions are needed for outdoor malaria transmission, including alternative designs for ITNs, and improving access to complementary personal protective measures.

The aspects of the use of cosmetology services nomenclature in medical organizations

Aim – to study the practice of use of the cosmetology services nomenclature in medical organizations. Material and methods. The Clinic of beauty and health "New Life" (Samara, Russia) was the base of the study. We analyzed its business practices and made a review of regulatory documents and scientific literature on the use of cosmetology services nomenclature. The analytical method and the content analysis method were applied. Results. Currently, there is a situation when one medical cosmetology service is called differently in various documents related to medical care provision: in medical documentation, in the contract for the provision of medical services, in informed voluntary consent to medical intervention and other documents, defining medical services in different terms. Conclusion. For responsible professional communication and awareness of generally accepted methods of diagnosis, treatment and prevention in the provision of medical care in the "cosmetology" profile, it is necessary to unify the terminology of cosmetology services within the current nomenclature of medical services.

Advanced Antimicrobial and Anti-Infective Strategies to Manage Peri-Implant Infection: A Narrative Review

Advanced Antimicrobial and Anti-Infective Strategies to Manage Peri-Implant Infection: A Narrative Review

Framing Analysis: Do Illegal Online Loans Have Fraud

This study aims to examine how the framing of news illegal online loan fraud in online mass media which is then used as information to find out the causes of the fraudulent practices. The Pan and Kosicki framing analysis method, which was extended with the fraud hexagon theory, were used. The sites in this study were online mass media, particularly tribunnews.com and kompas.com, reporting cases of fraud committed by illegal online lending companies. The results of the framing analysis on the news published by Tribunnews.com show that illegal online lending companies have committed fraudulent practices to their customers and their existence is very disturbing to the public. Kompas.com uses a more preventive method by revealing the ways that the people should do to avoid these traps and fraud. The results of the analysis using the fraud hexagon theory show that fraudulent practices committed by illegal online lending companies are caused by pressure from capital owners, information technology capabilities owned, broad market opportunities, rationalization that people need fast funds, ego, and binding agreements as a form of collusion. The increasing role of the government in providing protection for the public in online transactions is an important implication of this research.