Prevention Of Health Disorders Research Articles

A review on mushrooms as a versatile therapeutic agent with emphasis on its bioactive constituents for anticancer and antioxidant potential

Mushrooms, due to their many medical, preventive, and nutraceutical purposes, as well as their reputation as a folk remedy, have long been an integral part of traditional cuisines. The therapeutic advantages of mushrooms may be attributed to their bioactive components, including polysaccharides (both low and high molecular weight), terpenoids, phenolic compounds, fatty acids, lectins, and glucans. The bioactive components have been discovered to possess various health advantages, including antibacterial, antifungal, anticancer, radical scavenging, cardiovascular, anti-hypercholesterolemia, and anti-diabetic effects. These effects have gained worldwide attention and stimulated interest in further investigating their potential applications. Functional foods have the dual purpose of serving as both nourishment and medication. They may assist in the management and prevention of health disorders that are not functioning optimally, as well as mitigate some adverse effects of life-threatening diseases. Further evaluation is necessary to fully understand the mechanisms via which mushrooms operate and improve their therapeutic properties. This review delves into the possible medicinal potential of mushrooms and the advantages they may provide to human health.

Path to adventure: a qualitative exploration of provider training for adventure-based prevention practice

ABSTRACT Despite the utilization of adventure therapy techniques in behavioral health disorder prevention programming, little is known about how providers become trained in adventure-based prevention practice. Additionally, limited literature examines how adventure therapy providers are trained. This exploratory qualitative study provides a starting point for understanding the education and lived experiences that prepared providers of adventure-based prevention for professional practice. A purposive sample of 23 clinicians and administrators participated in semi-structured interviews with the first author. Interviews were transcribed and analyzed using thematic analysis with first-cycle coding, second-cycle coding, and in-vivo coding. Strategies to ensure the trustworthiness of the data were utilized including researcher reflexivity, memoing, intercoder reliability, triangulation, in-vivo coding, and member checking. Primary themes were providers’ lived experiences leading to adventure-based work, education & training, and mentorship. Discussion of new findings about preparation and education for adventure-based prevention are offered. Implications are described for practice, policy, research, and education.

The marine factor 3,5-dihydroxy-4-methoxybenzyl alcohol prevents TNF-α-mediated impairment of mineralization in mouse osteoblastic MC3T3-E1 cells: Impact of macrophage activation

The phenolic antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol (DHMBA), found in the Pacific oyster Crassostrea gigas, is a superior peroxyl radical scavenger compared to other materials, including Trolox. DHMBA may play an important role in the prevention of health disorders. This study elucidates whether DHMBA prevents the impairment of mineralization of mouse osteoblastic MC3T3-E1 cells under inflammatory conditions by using mouse macrophage RAW264.7 cells in vitro. Culturing with DHMBA (1–100 μM) did not affect the proliferation and death of MC3T3-E1 cells. DHMBA stimulated osteoblastic mineralization. DHMBA blocked the decrease in mineralization of MC3T3-E1 cells caused by culture with the inflammatory cytokine TNF-α. DHMBA inhibited the production of TNF-α by stimulation with lipopolysaccharide (LPS) in RAW264.7 cells. The growth of MC3T3-E1 cells was suppressed by coculture with macrophages under LPS stimulation through the crosstalk of both cells. Interestingly, the growth of MC3T3-E1 cells was suppressed by culturing with the conditioned medium obtained by culturing macrophages with LPS. The effect of the conditioned medium was blocked by the presence of DHMBA or Bay 11–7082, an inhibitor of the TNF-α pathway. The blocking effect of DHMBA was not further enhanced in the presence of Bay 11–7082. Mechanistically, DHMBA was found to decrease the levels of NF-κB p65 and the activity of NF-κB reporter expression in MC3T3-E1 cells. DHMBA was shown to prevent the impairment of osteoblastic mineralization via TNF-α signaling involved in macrophage activation in the bone marrow microenvironment. This study may provide a novel strategy for the therapy of osteoblastic impairment.

Occupational risk of developing chronic non-communicable diseases in bearing production workers

Introduction. Prevention of chronic non-communicable diseases, maintaining health and prolonging the occupational longevity of the working population is the most important strategic direction of the state policy of the Russian Federation in the field of public health
 The purpose. Stratification of the occupational risk of developing chronic non-communicable diseases among workers in the production of bearings for the subsequent development of specialized targeted programs for the prevention of health disorders.
 Material and methods. An assessment of the occupational risk of developing chronic non-communicable diseases among workers in the production of bearings is given on the basis of complex studies of production factors, primary and general chronic morbidity using the methodology for assessing occupational health risk.
 Results. It has been established that the development of chronic non-infectious diseases in bearing production workers is determined by a complex of harmful (classes 3.2–3.4) factors of the working environment of various nature, which form an occupational health risk in categories from medium to very high. In the structure of the general chronic non-infectious morbidity of workers, diseases of the eye and its adnexa (24.4%), diseases of the musculoskeletal system and connective tissue (20.7%), diseases of the circulatory system (19.32%) and diseases of the endocrine system had the highest prevalence in systems of eating disorders and metabolic disorders — 15.1%. A causal relationship of varying severity with the work of the most common nosological forms of chronic was revealed as arterial hypertension (RR = 1.425; EF = 29.837%; C = 1.044–1.945), obesity (RR = 1.731; EF = 42.24%; CI = 1.219–2.459), presbyopia (RR = 2.443; EF = 59.071%; CI = 1.549–3.855), indicating their occupational conditioning.
 Limitations. The limitation of the study was the assessment of the occupational risk of developing chronic non-communicable diseases in one occupational cohort of workers. 
 Conclusion. The development of specialized programs for the prevention of chronic non-communicable diseases among workers should include the study of causal aspects of health disorders and the rationale for measures to minimize the impact of occupational risk factors for occupationally determined pathology.

Hygienic assessment of the chemical factor of working conditions and respiratory disorders in metalworking workers

The study of the function of external respiration for the purpose of prenosological diagnosis of respiratory pathology related to work is an urgent task in the development of measures for the prevention of health disorders in 
 workers.
 The study aims to conduct a hygienic assessment of the chemical factor of working conditions and indicators of respiratory function in metalworking workers engaged in the metalworking process using lubricant cooling liquids.
 We have examined 250 male workers of the Saratov metalworking enterprise. The main group consisted of 145 people working in contact with lubricants and coolants, the control group consisted of 105 people not in contact with lubricants and coolants. The researchers have conducted a hygienic assessment of the chemical factor of working conditions in the workplace and a spirometric study of the function of external respiration in workers. The results of the study were statistically processed using the Statistica 10 program. The concentrations of chemicals in the workers' breathing zone comply with the hygienic requirements for the air of the working area corresponding to permissible working conditions (Class 2). According to spirometry data, the researchers have identified respiratory function values corresponding to the appropriate values, in the absence of statistically significant differences in spirometric indicators between the main and control groups.
 To identify the etiological contribution of chronic exposure to lubricants and coolants to the formation of respiratory pathology of workers, it is necessary to conduct additional in-depth clinical, laboratory, functional and epidemiological studies taking into account pollutants present in the air of the working area and their combined effects.
 Ethics. The studies were conducted in compliance with Ethical standards and principles of conducting medical research with human participation, set out in the Helsinki Declaration of the World Medical Association (ed. 2013). Written consent of respondents was obtained to participate in the study. The study was approved by the local Ethical Committee of the Saratov Hygiene Research Center of the Federal State Budgetary Institution "Federal Research Center for Medical and Preventive Technologies of Public Health Risk Management" (Protocol No. 10 of 03/16/2023).

ОХРАНА ЗДОРОВЬЯ РАБОТАЮЩЕГО НАСЕЛЕНИЯ С ПОЗИЦИЙ ПРОМЫШЛЕННОЙ И ВОССТАНОВИТЕЛЬНОЙ МЕДИЦИНЫ

The article presents a review of foreign literature on the main approaches to protecting the health of the working population from the standpoint of industrial and restorative medicine. The article discusses the problems associated with psychosocial risks and stressful impacts at work / production, substantiates the need to implement measures based on the principles of prevention, recovery and rehabilitation. It is emphasized that today, requirements for working conditions, control over production processes, the relationship between requirements in the field of health protection of workers and their labor protection, as well as psychosocial factors - uncertainty at work, distracting breaks, lack of team spirit and etc. The policy of the enterprise, relevant industries, and the state itself in the field of protecting the health and life safety of workers is of decisive importance for the health of the working population. Teamwork involves not only the participation of health and safety employees, but also the employees and employers themselves at the respective workplaces / production sites, as well as the involvement of third-party experts. Sustainable employment of the working population is associated, according to scientists, with such aspects as maintaining and restoring the health of workers, economic productivity, social utility and a favorable long-term outlook. Problems of risks for workers require an integrated approach to the development of measures aimed at primary prevention, including the prevention of overwork, changing the style and organization of work, strengthening and maintaining health in general. An approach is considered important for preserving and restoring the health of the working population when it is advisable to combine measures for the primary prevention of health disorders not only with measures to optimize the organization and working conditions, but also with modern technologies of preventive and restorative medicine.

MENTAL HEALTH AND MENSTRUAL HEALTH AMONG OBG POST GRADUATE STUDENTS DURING CORONA PANDEMIC TIMES

BACKGROUND & OBJECTIVE: Research suggests that medical students, as well as women, are at greater risk of depression, compared to the general population and men. Various studies have proven that mental health adversely affects menstrual health causing irregular periods, shorter cycles (<28 days). This suggests that female medical students are crucial targets requiring specic monitoring for mental health disorder prevention and intervention. Therefore, the aim of the present study is to analyze whether menstrual health is associated with Mental Health among female medical OBG [Obstetrics and gynecology postgraduate students. MATERIALS & METHODS: A self-reporting questionnaire was used to perform the research. A total of 250 postgraduates were issued the questionnaire, and 200 postgraduates responded. The survey was completed and personal information was gathered, then uploaded to a Microsoft Excel sheet for analysis. RESULTS: The analysis showed that out of 200 responders of female postgraduates 49.6% of doctors were found to be suffering from stress with the menstrual problems in the current pandemic situation indicating mental health difculties having a negative impact on the menstrual period. The correlation between mental health and the menstrual cycle was shown to be signicant [p - <0.05]. CONCLUSION: Thus it is important to recognize the mental health of OBG postgraduates, as well as nd solutions to the underlying reasons, in order to rescue the current and future of healthcare from mental health crises.

Prevalence and Sociodemographic Factors Associated with Overweight and Obesity among Adults in Poland: A 2019/2020 Nationwide Cross-Sectional Survey.

Detailed characteristics of the weight status of the population is necessary for the effective prevention of health disorders, e.g., through personalized nutrition education. This study aimed to characterize weight status and identify sociodemographic factors associated with overweight/obesity in a representative sample of adult inhabitants of Poland. This cross-sectional study was carried out from July 2019 to February 2020 on a representative nationwide sample of individuals aged 18+ in Poland. The study consisted of two parts: questionnaire survey and anthropometric measurements. The body mass index was calculated. Data on 1831 adults (50.3% females; mean age 51.7 ± 19.9 years) were included in this analysis. The prevalence of overweight was 42.2% (52.4% among males and 32.0% among females). Of the 1831 participants, 16.4% were obese (16.5% of males and 16.2% of females). Out of 11 factors analyzed in this study, only 5 were significantly associated with overweight/obesity. Males, older participants, occupationally active individuals, those living in rural areas and individuals with at least one chronic disease had greater odds of overweight/obesity. This study demonstrated a high prevalence of overweight and obesity among adults in Poland. This is the most up-to-date representative study on nutritional status carried out before the COVID-19 pandemic.

UKRAINIAN YOUTH LIFESTYLE PECULIARITIES WITH THE EYES OF A TEENAGER AND HIS MOTHER

The most important criterion for assessing the well-being of society, a factor in the national security of the country is the health of the younger generation. The state of health of adolescents is largely determined by the level of valeological education in the family. After all, the family develops the skills of a healthy lifestyle, universal spiritual values, and norms of social life. The main task today, on the one hand, is to study and identify the factors of individual and family health and social risk, and on the other hand - to optimize the early diagnosis and prevention of health disorders in children. The formation of skills for a healthy lifestyle of adolescents is crucial for the spiritual and physical development of the younger generation, its formation as a social personality. The paper examines the problems of forming a healthy lifestyle of Ukrainian adolescents aged 15-18, whose socialization takes place in the information society, which is implemented by processing 1,075 sets of questionnaires ("Questionnaire of adolescents 15-18 years" and "Questionnaire of mothers of adolescents 15-18 years"), in the analysis of which only informative answers were taken into account. Information base - the international program ELSPAC - (European Longitudinal Study of Parenthood and Childhood - European long-term monitoring of parenthood and childhood), its Ukrainian fragment "Family and Children of Ukraine".
 It was found that the main source of information for adolescents is a computer with the Internet and television (71.3 and 66.4% of respondents, respectively). The results of the survey of adolescents on the place of work at the computer showed that for the most part - 79.2% of respondents work at home, a third at school - 37.2% and 17.2% of adolescents - in the computer club (17.2%). The maximum number of answers confirms that both on weekdays and weekends the duration of work on the computer is from 1 to 6 hours with a maximum value of 2 hours for working days (23.6%) and 4 hours - on weekends and holidays (15.7%)). Information on the negative impact on the human body of long-term computer use is known to the vast majority of respondents - 95.8% of adolescents. The majority of respondents for offline communication prefer peers, some loyal friends (63.4 and 60.7%, respectively), only 45.2 and 40.4% of adolescents like to communicate with their parents and beloved person, respectively. An analysis of literary preferences found that one in four to five teenagers enjoyed reading school literature, comics, humor and science fiction, short stories and novels, encyclopedias and dictionaries.
 The results of the survey of mothers of adolescents on the assessment of the daily routine and daily activity of their children prove insufficient physical activity; only 35.7% of adolescents go in for sports in their free time. Home help is most often provided by a teenager making his bed (70.8% of cases), cleaning his room and going to the store (55.6 and 51.1%, respectively). Survey of mothers on the living conditions of their children's sleep showed that the vast majority of them sleep in a separate room (70.0% of adolescents), in a room with other children - 15.3% of respondents, with parents - 9.0% of children in the room with other adults - 2.9% of adolescents. But 3.3% of children do not have a single bed.
 Summing up the results of the responses of Ukrainian adolescents and their mothers, it is possible to say that in our society, due attention is not paid to the employment of adolescents. Thus, improving the quality of life of adolescents can be achieved by choosing the optimal preventive effect on them, taking into account the individual characteristics of psychological and physical status.

Assessment of the Adequacy of Amateur Sports by the Functional Status of Students

Background: In the right dose, physical activity can bring health benefits. Objectives: To assess indicators of health and physical development of students engaged in amateur sports. Materials and methods: The study involved 30 male students aged 23.8 ± 0.3 years. We established their daily energy expenditures, integral indices characterizing their physical development, such as body weight, Pignet, strength, vitality, and Kerdo vegetative indices, endurance rate, circulatory efficiency, and the index of functional changes. We also analyzed cardiovascular system parameters including heart rate, systolic and diastolic blood pressure at rest, after exercise and after exercise recovery. Results of the biochemical blood test taken the next morning after workout were used to evaluate the status of functions and systems of the body. Results: Energy expenditures amounted to 3,665.5 ± 37.3 kcal. Students were physically strong, their functional capabilities of the respiratory system and adaptation to sports (according to the activity of the parasympathetic autonomic nervous system) were found satisfactory while their physical activity was assessed as high (hard work). In the body, catabolic processes prevailed, and the level of cortisol exceeding the norm in 50.0 % of the subjects indicated stress. Inadequacy of physical exercises was evidenced by the index of functional changes (in 57.7 % of the students adaptation was in the state of functional stress); reaction of the cardiovascular system (endurance and heart rates, circulatory efficiency, creatine kinase MB, troponin-1, ALT, and LDH); increased erythropoiesis; hormonal changes (cortisol, testosterone); changes in the metabolism of proteins (total protein, urea, uric acid), fats (total cholesterol, high- and low-density lipoproteins), and hormones (cortisol, testosterone); signs of an early stage of anemia (erythrocytes, total protein, ferritin). Conclusion: The use of the methodology for assessing the functional status of the human body by integral and biochemical criteria during recovery period after exercise enables pre-nosology diagnostics and prevention of health disorders during active sports.

Analyzing the Impact of COVID-19 Trauma on Developing Post-Traumatic Stress Disorder among Emergency Medical Workers in Spain.

The early stages of the COVID-19 pandemic presented the characteristics of a traumatic event that could trigger post-traumatic stress disorder. Emergency Medical Services workers are already a high-risk group due to their professional development. The research project aimed to analyse the impact of the COVID-19 pandemic on EMS professionals in terms of their mental health. For this purpose, we present a descriptive crosssectional study with survey methodology. A total of 317 EMS workers (doctors, nurses, and emergency medical technicians) were recruited voluntarily. Psychological distress, post-traumatic stress disorder, and insomnia were assessed. The instruments were the General Health Questionnaire-12 (GHQ-12), the Davidson Trauma Scale (DTS-8), and the Athens Insomnia Scale (AIS-8). We found that 36% of respondents had psychological distress, 30.9% potentially had PTSD, and 60.9% experienced insomnia. Years of work experience were found to be positively correlated, albeit with low effect, with the PTSD score (r = 0.133). Finally, it can be stated that the COVID-19 pandemic has been a traumatic event for EMS workers. The number of professionals presenting psychological distress, possible PTSD, or insomnia increased dramatically during the early phases of the pandemic. This study highlights the need for mental health disorder prevention programmes for EMS workers in the face of a pandemic.

The impact of the labor process severity on the formation of health disorders of protected ground grower

Introduction. The severity of the labor process is one of the leading harmful factors of working conditions in greenhouse vegetable growing. Nevertheless, its influence on the formation of health disorders of vegetable growers has not been sufficiently studied. Material and methods. Physiological, hygienic and epidemiological studies were carried out, which included an assessment of the severity of work in the annual cycle, also the functional state of the cardiorespiratory system and the neuromuscular system in the dynamics of the work shift, the general morbidity of vegetable growers according to registration forms No. 025/y. Results. During the labor activity, vegetable growers were established to be exposed to physical overloads caused by the severity of the labor process (classes 3.2, 3.3) in combination with a heating microclimate (classes 3.1-3.3). By the end of the work shift, there was an increase relative to the initial levels of heart rate (p<0.05), a decrease in systolic and diastolic blood pressure, a reduction of maximum muscle strength (by 3.76-5.28%), and endurance of the muscles of the hands (by 18.5-33.15%). This indicated a decrease in working capacity and an increase in fatigue. A reduction in the Skibinski index (by 21.7%) and an increase in the index of resistance to hypoxia (by 38.9%) indicated a decrease in the body’s reserves of oxygen. Increased working levels of the index of functional changes testify about the tension of adaptation mechanisms and insufficient restoration of the body’s resources by the beginning of the shift. A decrease in the body’s physical condition and adaptive capabilities with an increase in professional experience was revealed (p<0.05). There were established statistically significant direct correlations between the prevalence of diseases of the circulatory system (r=0.6), musculoskeletal system, and connective tissue (r=0.35) with work experience in the profession (p<0.05). Conclusion. The revealed violations of the functional state and health of female vegetable growers result from the influence of physical overload in a heating microclimate. The priority measures for the prevention of health disorders of vegetable growers are to reduce physical overload and thermal effects of the working environment.

Current problems of healthy working conditions and prevention of health disorders of agricultural mechanizers during the operation of self-propelled grain harvesters

The prevention of work-related health disorders is a priority in hygiene and preventive medicine. However, little attention has yet been paid to occupational health issues for agricultural workers. The purpose of this research was to assess the current state and develop measures to improve working conditions during the operation of self-propelled combine harvesters, the most widely represented in the existing machine and tractor fleet of agriculture in Russia. Measurements and hygienic assessment of the parameters of the factors of the production environment and the labor process in real production conditions have been carried out. The research results showed that the working conditions on self-propelled combine harvesters are characterized by a complex effect on workers of unfavorable factors (dustiness of the air in the working area, microclimatic discomfort, noise, general and local vibration, physical and sensory-emotional overload), the levels of which to varying degrees exceed hygienic standards. (classes 3.1–3.4). It has been established that the main reason for the formation of harmful working conditions is the operation of morally and physically worn out equipment. It is shown that the impact of an unfavorable production environment can serve as a risk factor for the emergence and development of general and occupational pathology among agricultural machine operators. A set of measures has been developed to ensure safe working conditions and reduce the risk of health disorders for machine operators, including normalizing the microclimate, reducing noise, vibration, dustiness in the air in the working area, optimizing the working posture, and introducing rational modes of work and rest. However, the basic measure that minimizes the adverse impact of professionally determined production factors on the health of agricultural machine operators is the complete replacement of the outdated machine and tractor fleet with agricultural machinery of new generations and compliance with the terms of its operation.

Improving early detection of reproductive health through empowering cadres in Kepuharjo village, Cangkringan, Sleman

After the catastrophic eruption of Merapi, which was very traumatic, some people had to move to a new neighbourhood which also was a stressor and further might cause mental disorders, especially women's psychiatric disorders. Prolonged stress will suppress the immune system which affects reproductive health, such as menstrual disorders, vaginal discharge, and urinary tract infections. One of the efforts to deal with this problem is to provide assistance related to early detection and overcoming reproductive health disorders for PKK cadres. The purpose of this study was to evaluate the PKK cadre’s skills in early detection and control of reproductive health disorders and to evaluate the decrease of women’s reproductive health disorders in Kepuharjo Village. The target of this study consisted of 40 PKK cadres and 60 women in Kepuharjo Village, Sleman. The early detection module, reproductive health disorder prevention module and early detection skills, reproductive health disorder prevention module, and urine and pap smear laboratory tests were used in the research. The data was presented in quantitative descriptive, using secondary data from community service in June-October 2017. The results of this study were (1) Increasing the average value of early detection skills for reproductive health disorders: stress increased from 39.83 to 57.5; menstrual disorders increased from 29.65 to 57.5; UTI disorders increased from 29.52 to 53.75; vaginal discharge disorders increased from 26.25 to 56.25; breast cancer increased from 16.25 to 51.25. (2) Increasing the average value of reproductive health disorders prevention skills: humour games increased from 41.25 to 82.5 and social support increased from 27.25 to 62.5. (3) Decreased tendency of women’s reproductive health disorders: stress decreased from 39 people (65%) to 21 people (35%); menstrual disorders fell from 51 people (85%) to 31 people (17.67%); UTI disorders decreased from 25 people (41.67%) to 16 people (26.67%); and vaginal discharge decreased from 34 people (56.67%) to 19 people (31.67%). It can be concluded that empowering cadres can improve PKK cadre’s skills in early detection of reproductive health disorders and overcoming reproductive health disorders.

Psychosocial occupational factors and the risk of health issues in healthcare workers (thematic review)

Based on the thematic review of the Russian and foreign studies the analysis of the contemporary views on the occupational psychosocial and traditional factors as the determinants of stress in healthcare workers was conducted. The data on the stress-induced health disorders with the psychosomatic pathology, in particular, cardiovascular diseases and occupational burnout syndrome, is provided. The prospects of primary prevention of health disorders based on the use of stress markers to prevent the development of diseases of the circulatory system and occupational burnout in the medical environment are considered

Main approaches to prevention of health disorders in workers in contact with physical factors

Introduction. One of the leading causes of occupational health loss, especially in mining and machine-building enterprises, is the combined impact of industrial noise and vibration. The wide prevalence of cardiovascular diseases is one of the most important medical and social problems, due to persistent disability and high mortality, bringing prevention of health disorders to the first place as the basis for preserving labor longevity. The aim of study is to identify the main approaches aimed at preventing health problems in workers who come into contact with vibration and noise at mining and machine-building enterprises. Materials and methods. A survey and survey of 296 industrial workers was conducted. Group 1 (160 people) included men who were exposed to noise and vibration factors above the maximum permissible levels, group 2 consisted of 136 men who did not have direct contact with noise and vibration generating equipment. When conducting an in-depth laboratory and instrumental examination in a hospital setting, all workers additionally calculated the level of cardiovascular risk on the SCORE scale. Statistical analysis was performed using the software package "Statistica 6.0". Results. It is determined that the priority adverse factors of the working environment in production are noise and vibration. It has been shown that individuals who come into contact with these factors are more likely to detect violations of lipid metabolism and endothelial function, have a higher average heart rate and systolic blood pressure, and have an increased risk of developing cardiovascular diseases. Conclusions. Taking into account the obtained results of the proposed diagnostic approaches aimed at the prevention of health disorders among workers of industrial enterprises. If employees are found to have an increased cardiovascular risk, it is necessary to conduct a more in-depth examination and timely medical and preventive measures.

Ergonomic risk factors for the development of disorders of the musculoskeletal system in adolescents

Prevention of health disorders and sexual development of society is a priority area of hygiene and preventive medicine. The introduction of information and communication technologies into the educational process is a new risk factor for the development of disorders of the musculoskeletal system in adolescents. Purpose of the study: assessment of ergonomic risk factors for the development of disorders of the musculoskeletal system in adolescents using personal electronic computers as teaching aids. Objects of research: sanitary-hygienic and ergonomic factors of learning conditions with the use of personal computers and the state of the musculoskeletal system of college students. Research in accordance with the requirements of bioethics, after signing the informed consent and their parents. The hygienic factors of the learning environment and the ergonomic characteristics of furniture (tables, work chairs) in computer science classes of the Saratov college were studied. Their assessment is given for compliance with sanitary and epidemiological requirements and anthropometric indicators of students. A questionnaire survey and physical examination of 308 adolescents were carried out to identify complaints and assess the condition of the musculoskeletal system. It has been established that the organization and ergonomic characteristics of workplaces equipped with electronic computers fully comply with hygienic and ergonomic requirements. This is the cause of postural disorders and the development of disorders of the condition of the musculoskeletal system of students. A high prevalence of clinical signs of disorders of the musculoskeletal system among adolescents was revealed. It has been established that compliance with ergonomic requirements in the organization of workplaces when using personal electronic computers is a prerequisite for the primary prevention of disorders of the musculoskeletal system in adolescents. To solve this problem, first of all, it is necessary to provide educational institutions with modern furniture that meets ergonomic requirements.

Оценка вероятности развития коморбидности заболеваний нервной системы и органов пищеварения у детей при сочетанном воздействии химических факторов и факторов образовательного процесса

Hygienic assessment of combined effects produced by heterogeneous factors on comorbid diseases in the nervous system and digestive organs in children is vital for early detection and prevention of health disorders given existing risks and threats. Our research goal was to estimate probability of comorbid diseases in the nervous system and digestive organs in children attending primary schools under combined exposure to chemical factors and factors related to the educational process. Our research objects were factors related to the educational process that produced their effects on children aged 7–10 who attended primary schools with different educational programs; chemicals contents in ambient air and air inside classrooms as well as in children’s blood; biochemical parameters of negative effects; models showing cause-and-effect relations. Our research results allowed us to identify priority influencing factors and their share contributions into negative effects development in case there was comorbidity with nervous system diseases and digestive organs diseases; to give grounds for biological markers of negative effects applied for early diagnostics and development of activities aimed at preventing comorbid disorders for schoolchildren. Implementation of an algorithm for calculating and estimating probability of comorbid diseases in the nervous system and digestive organs under combined exposure to heterogeneous factors involves determining additional comorbidity cases among children who attend schools with more comprehensive educational programs in comparison with children attending ordinary schools. Timely and adequate correction of detected influencing factors and development of activities aimed at preventing comorbid health disorders will allow minimizing risks of comorbid diseases in the nervous system and digestive organs in school children under combined exposure to chemical factors existing in the environment and inside classroom and factors related to the educational process.

Assessing probability of comorbid diseases of the CNS and digestive organs in children under combined exposure to chemical factors and factors related to educational process

Hygienic assessment of combined effects produced by heterogeneous factors on comorbid diseases in the nervous system and digestive organs in children is vital for early detection and prevention of health disorders given existing risks and threats. Our research goal was to estimate probability of comorbid diseases in the nervous system and digestive organs in children attending primary schools under combined exposure to chemical factors and factors related to the educational process. Our research objects were factors related to the educational process that produced their effects on children aged 7–10 who attended primary schools with different educational programs; chemicals contents in ambient air and air inside classrooms as well as in children’s blood; biochemical parameters of negative effects; models showing cause-and-effect relations. Our research results allowed us to identify priority influencing factors and their share contributions into negative effects development in case there was comorbidity with nervous system diseases and digestive organs diseases; to give grounds for biological markers of negative effects applied for early diagnostics and development of activities aimed at preventing comorbid disorders for schoolchildren. Implementation of an algorithm for calculating and estimating probability of comorbid diseases in the nervous system and digestive organs under combined exposure to heterogeneous factors involves determining additional comorbidity cases among children who attend schools with more comprehensive educational programs in comparison with children attending ordinary schools. Timely and adequate correction of detected influencing factors and development of activities aimed at preventing comorbid health disorders will allow minimizing risks of comorbid diseases in the nervous system and digestive organs in school children under combined exposure to chemical factors existing in the environment and inside classroom and factors related to the educational process.

Association between nutritional level, menstrual-related symptoms, and mental health in female medical students.

ObjectiveResearch suggests that medical students as well as women are at greater risk of depression compared to the general population and men. This suggests that female medical students are crucial targets requiring specific monitoring for mental health disorder prevention and intervention. However, little is known regarding the risk factors for poor mental health among this population. Therefore, we investigated whether menstrual symptoms and nutritional status are associated with psychological distress in Japanese female medical students.MethodsThis cross-sectional study assessed 326 female medical students who attended a school medical check-up, which included blood sampling in 2018. The levels of psychological distress were evaluated using the Japanese General Health Questionnaire (J-GHQ)-30. We defined high GHQ scores as GHQ-30 ≥7. We checked dysmenorrhea levels and assessed menstrual symptoms according to the presence of premenstrual syndrome (PMS). Dysmenorrhea was evaluated according to quartiles of the sum of the Menstrual Distress Questionnaire (MDQ). PMS was assessed using the Premenstrual Symptoms Questionnaire (PSQ). We evaluated levels of serum albumin, hemoglobin, ferritin, and lipid metabolite as nutritional factors. A multivariate logistic regression analysis was used to identify the association between menstrual-related symptoms or nutritional factors and the levels of psychological distress.ResultsA total of 45 female medical students (15%) experienced psychological distress. Serum albumin levels were associated with psychological distress, while lipid metabolite levels were not. The intensity of dysmenorrhea and the presence of PMS were associated with psychological distress, independent of nutritional status.ConclusionBoth menstrual symptoms and nutrition markers were associated with the levels of psychological distress in Japanese female medical students. School doctors and nurses can help improve the mental health of young female medical students by encouraging a healthy diet and checking for the presence of menstrual symptoms.