Prevalence Rates Of Depression Research Articles

The relation between insomnia and depression in the subacute phase after stroke

The relation between insomnia and depression in the subacute phase after stroke

Prevalence, Correlates, and Comorbidities Among Young Adults Who Screened Positive for ADHD in South Korea During the COVID-19 Pandemic

Objective: This study examined the prevalence, associated factors, and psychiatric comorbidities of adult ADHD during the COVID-19 pandemic by analyzing nationally representative data. Methods: Among the 5,511 respondents of the 2021 National Mental Health Survey, South Korea, 2,764 (18–49 years) were selected. The Korean versions of the Adult ADHD Self-Report Scale, Composite International Diagnostic Interview, and Structured Clinical Interview for Internet Gaming Disorder were used as diagnostic assessments. Results: The 6-month prevalence of positive screens for adult ADHD was 3.1%. In individuals aged 18 to 29 years exhibiting adult ADHD symptoms, high prevalence rates of alcohol use, depression, and Internet gaming disorders were observed in the last 12 months. Adults who screened positive for ADHD reported significantly lower life satisfaction and resilience, and higher loneliness and social isolation (vs. non-ADHD group). Conclusion: Adult ADHD symptoms significantly influenced mental well-being, highlighting the need for an appropriate treatment/prevention system, particularly for individuals aged 18 to 29 years.

Analysis of patient health questionnaire-9 (PHQ-9) based depression prevalence according to a discordance between quantitative urinary cotinine levels and self-report of second-hand smoke exposure among adults: A cross-sectional study

BackgroundSecond-hand smoke (SHS) exposure appears to be more common among individuals with depression. However, self-report of SHS exposure is an inaccurate classification compared to confirming SHS exposure using urinary cotinine (UC). Additionally, the dose-response relationship between depression and UC is controversial. MethodsThe severe stress rate and depression prevalence was estimated among 14530 Korean participants aged ≥19 years using data patient health questionnaire-9 (PHQ-9) and on UC from the Korean National Health and Nutrition Examination Survey. Measured UCs were divided into four categories: UC– (≤0.3 μg/L), UC± (0.4 μg/L–0.9 μg/L), UC+ (1.0 μg/L–11.9 μg/L), and UC++ (≥12.0 μg/L). ResultsAbout 55.0 % participants were female and participants’ mean age was 51.1 years. Non-smokers were 80.3 %. Among non-smokers, non-SHS exposure participants (SR–) and SHS exposure participants (SR+) were 83.0 % and 17.0 %, respectively. When UC– was used as the reference subgroup, the UC++ subgroup showed a higher depression prevalence, whereas the UC ± subgroup showed a lower prevalence. In the same UC categories, the depression prevalence and severe stress rate were higher among females than among males. Furthermore, the SR + subgroup had a higher severe stress rate than the SR– subgroup. ConclusionsOur study showed a paradoxical reduction in the depression prevalence and severe stress rate in the UC ± subgroup compared to the UC– subgroup. Additionally, the dose-response relationship between the SHS exposure biomarker and the depression prevalence was not linear. Our study indicates that an emotional stress-based model may be more appropriate for explaining the relationship between depression and SHS exposure.

Psychiatric Disorders Are Common Among Older US Veterans Prior to Traumatic Brain Injury.

To estimate the impact of traumatic brain injury (TBI) on prevalence of posttraumatic stress disorder (PTSD), depression, and alcohol and substance use disorders. A random sample of Veteran's Health Administration data. A total of 14116 veterans aged≥55 with incident late-life TBI between October 1, 1999, and September 31, 2021, were matched 1:3 on age and TBI date to 42678 veterans without TBI. Retrospective cohort study. PTSD, depression, and alcohol and substance use disorders were identified using diagnostic codes. Participants were censored after the first diagnosis during the year before and the year after the TBI or matched date. Prevalence rates of PTSD, depression, alcohol, and substance use disorders were compared before and after incident TBI or matched date using Poisson regression. Pre-TBI prevalence rates of disorders were higher among those with TBI relative to those without TBI. Pre-TBI PTSD prevalence rates (per 1000 person-years) were 126.3 (95% CI, 120.2-132.4) compared to 21.5 (95% CI, 20.1-22.9) in the non-TBI cohort. In adjusted models, TBI was not associated with an increase in the prevalence of any of the studied disorders. Prevalence rates of depression, PTSD, and alcohol and substance use disorders were 5 to 10 times higher among older veterans before incident TBI. We did not observe an increase in the prevalence of these disorders after incident TBI. Older veterans with these disorders may be at increased risk for TBI.

Psychological distress during the COVID-19 pandemic normalization phase in China: A multigroup latent profile analysis among healthcare workers and the general population

The COVID-19 pandemic is no longer considered a “global public health emergency”; nonetheless, it has left a long-lasting effect on people's mental health. Existing studies examined the impact of COVID-19 on people's mental health; however, most of these investigations were carried out during the acute phase. This study addresses the gaps in knowledge regarding the psychological distress experienced by healthcare workers and the general population in China during the normalization period, as well as the shared and distinct associated factors. Data were collected in March 2022. Five hundred and three healthcare workers and 307 general individuals participated. Online questionnaires were administered. Collected data for mental health indices included depression, anxiety, insomnia, and resilience. Various statistical analyses were conducted, including independent sample t-tests, chi-square tests, one-way analyses of variance, multigroup latent profile analyses, and multinomial logistic regression analyses. Healthcare workers had lower prevalence rates of depression and anxiety and a higher level of resilience than the general population. Latent profile analyses suggested four profiles based on levels of psychological distress (i.e., low, mild, moderate, and high) derived from four indices (i.e., depression, anxiety, insomnia, and resilience). The person-centered approach revealed that the general population had more individuals in moderate and high distress classes and fewer in the mild distress class. Healthy lifestyles, past mental health issues, and epidemic burnout were common influencing factors for both groups. However, epidemic uncertainty was identified as the distinct contributing factor for the general population. Directions for future research and interventions are discussed.

ANXIETY, DEPRESSION, AND PSYCHOTROPIC DRUGS USAGE BY UNIVERSITY STUDENTS OF MEDICAL GROUP IN BASRA, IRAQ

Background: Psychological disease is strongly prevalent among college and university students worldwide with negative impacts on students’ life. Specifically, medical group students have long time of study with suffer from competitive ambience and sleep privation, that lead to out of the way from perfect learning environment. When medical students are abused psychotropic drugs that lead to defect on performance, health, life style and interpose with their concentration. Aim: to investigate the prevalence rate of depression and anxiety in university students of medical group in Basra, and estimate the rate and type of psychotropic drugs consumption by them. Method: The study data was collected from 376 students of medical group at College of Medicine, College of Dentistry and College of Pharmacy of Basra University by questionnaire forma. Results: The prevalence rate of mental disorders was low about and many factors that affected on psychiatric state of them like gender, age, Family and friends Relation, missing one of parents etc. Among medical group students that used sedatives and hypnotics about (46%) than other psychotropic drugs like serotonin-norepinephrine reuptake inhibitor (SNRIs) (42.9%) tricyclic antidepressants (21.4%), and atypical antipsychotic (7.1%). Conclusions: Medical group students are more likely to consumption antipsychotic drugs by physician prescription or self-medications. Therefore, there are required more interesting and pursuits for college students especially medical college students for amelioration their college and social lives. Peer Review History: Received 6 February 2024; Revised 15 March 2024; Accepted 26 April; Available online 15 May 2024 Academic Editor: Dr. Asia Selman Abdullah, Pharmacy institute, University of Basrah, Iraq, asia_abdullah65@yahoo.com Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewers: Dr. A.A. Mgbahurike, University of Port Harcourt, Nigeria, amaka_mgbahurike@yahoo.com Prof. Hassan A.H. Al-Shamahy, Sana'a University, Yemen, shmahe@yemen.net.ye

India’s Silent Struggle: A Scoping Review on Postpartum Depression in the Land of a Billion Mothers

Background: Postpartum emotional issues, including postpartum blues, postpartum psychosis, and postpartum depression (PPD), affect many mothers worldwide. The prevalence of postpartum blues ranges from 300 to 750 per 1,000 mothers, while postpartum psychosis has a prevalence of 0.89–2.6 cases per 1,000 births. PPD affects 100–150 new mothers per 1,000 births, and its prevalence can go above 25% globally. Depression in mothers can have long-lasting impacts on children and the next generation, affecting their growth, development, and relationships. However, the condition of PPD is frequently misdiagnosed, and women who suffer from it do not receive treatment. There is a lack of solid systematic evidence that looks at the overall burden of PPD and the risk factors that are associated with it in India. The awareness of PPD is critical in managing the symptoms and seeking professional support, and studies are needed to evaluate and assess the situation in India. Methodology: This study is a systematic literature review with a scoping review approach aimed at providing existing evidence on the awareness and prevalence of PPD in India. The search strategy for the electronic bibliographic search included a list of related terms and factors of awareness and prevalence of PPD. The search encompassed six prominent databases. The assessment tools used in studies from 2012 to 2023 study the factors using the Postpartum Depression Literacy Scale (PoDLiS) and the Edinburgh Postpartum Depression Scale, which measure the awareness and prevalence of PPD. Results: The study found a significantly low volume of studies conducted in India to determine the prevalence of PPD. The materials or studies accessible are hospital-based research with a minimal number of samples. The reported prevalence rate of postpartum depression (PPD) in India varies across different studies, ranging from 4% to 48.5%. Among mothers who gave birth either naturally or by cesarean section in a hospital setting, one study reported the lowest prevalence rate (4%). The prevalence of PPD among women in India is estimated to be 18% based on the average score across all research. A study that evaluated the moms in the community found that PPD was prevalent in new mothers at a rate of 21.5%. There are three studies, in particular, that focus on how aware people are of PPD. Two studies found that 54% of the family members of postpartum moms and women undergoing tertiary pediatric care are aware of PPD. Discussion: Many studies point to the lack of social support as a significant risk factor for mental health complications after delivery. History of depression, anxiety, adverse life events, partner abuse, low economic status, complications at childbirth, and a traumatic childbirth experience are some of the associated factors identified in the studies. Studies have also shown that women who undergo a cesarean section have a higher risk of developing PPD than those with a vaginal delivery.

Social Support as a Correlate of Depression and Quality of Life Among Nigerian Older Adults: a Cross-Sectional Study.

Reduced social support has been associated with presence of depression and reduced quality of life among older adults. The relationships may be better understood by exploring the interactions of individual domains among the constructs. This cross-sectional survey involved a consecutive sample of 206 (116 females and 90 males) older adults living in a Southern Nigeria community. The Multidimensional Scale of Perceived Social Support, Geriatric Depression Scale, and World Health Organization Quality of Life-OLD Questionnaire, were used to measure social support, depression, and quality of life respectively. Data was analyzed using frequency counts, percentages, mean, standard deviation, multiple regression and Spearman rank-order correlation coefficient, at 0.05 alpha level. Prevalence rate of depression among participants was 45.5%. Social support was perceived to be low by 37.4% of participants with the lowest mean social support score coming from friends domain. Participants' quality of life was generally fairly good (> 60%) with the lowest scores coming from the intimacy domain. Significant correlations between social support domains and each of quality of life (p < 0.05) and depression were respectively positive and negative; but weakest for the friend and strongest for significant others domains. All quality of life domains were significantly correlated with social support except the death and dying domain. All the domains of social support (family and significant other) were significant predictors of depression except the friend domain. Significant others around individual older adults particularly those with depression ought to be educated on the importance of their roles. Stakeholders including healthcare providers may create and support programmes for improved social networking for the older adults in order to enhance their general wellbeing and quality of life.

Prevalence and factors associated with antepartum depression among adolescent women in the assin north district of Ghana: a cross-sectional study

BackgroundGlobally, depression is a leading cause of disease-related disability among women. In low-and-middle-income countries (LMICs), the prevalence rate of antepartum depression is estimated to range between 15% and 57% and even higher in adolescent antepartum women. Although a number of studies have shown that depression is common in adolescent pregnancies and has a prevalence rate between 28% and 67% among adolescent mothers, there currently exists no literature on depression among adolescent pregnant women in Ghana. The study aimed to determine the prevalence of antepartum depression and identify the factors associated with it among pregnant adolescent women.MethodsA quantitative cross-sectional study design was adopted by randomly recruiting 220 adolescent pregnant women visiting antenatal clinics in five selected health facilities in five communities in the Assin North District of Ghana. Data were collected using the Edinburgh Postnatal Depression Scale (EPDS). Data analysis was performed using Stata version 14. Both descriptive and inferential analyses were performed. A chi-square analysis was conducted to identify the association between independent and dependent variables. A multivariate logistic regression analysis was carried out to identify the independent variables that were significantly associated with the dependent variable. In all analyses, p-values ≤ 0.05 were deemed statistically significant at a 95% confidence interval.ResultsThe results indicated prevalence of depression was 38.6% using the EPDS cut-off ≥ 13. Respondents who were cohabiting were less likely to experiencing antepartum depression compared to those who were single (AOR = 0.36, 95% CI: 0.20–0.64, p = 0.001). Also, Respondents who had completed Junior High School had a lower likelihood of experiencing antepartum depression compared to those who had no formal education (AOR = 0.19, 95% CI: 0.05–0.76, p = 0.019). Respondents who perceived pregnancy-related items to be costly had higher odds of experiencing antepartum depression (AOR = 2.05, 95% CI: 1.02–4.12, p = 0.042). Lastly, adolescent pregnant women who reported that pregnancy-related items are costly were likely to experience antepartum depression compared to those who did not report such costs (AOR = 2.12, 95% CI: 1.20–3.75, p < 0.001).ConclusionThe results of this study highlight the importance of a multi-pronged strategy for combating antepartum depression in adolescents and improving the overall health and well-being of pregnant adolescents. Considering that adolescence is a transitional period occasioned by several bio-psycho-social challenges, setting up systems to ensure that young girls are motivated and supported to stay in school will enhance their economic prospects and improve their standards of life while providing psycho-social support will benefit their health and general well-being.

PREVALENCE OF DEPRESSION AND ANXIETY IN POLYCYSTIC OVARIAN SYNDROME WOMEN

Objective: The objective of the study was to determine the prevalence of depression and anxiety ranges in women having Polycystic Ovarian Syndrome (PCOS). Methods: An epidemiological observational study on 80 PCOS patients confirmed through ultrasound scanning over a study period of 6 mo at Government General Hospital, RIMS, KADAPA. HAM-D and HAM-A assessment scales were used to analyze the severity of depression and anxiety in PCOS women. Results: Among 80 patients, the prevalence of depression is 86.25% (n=69) and anxiety is 93.75% (n=75). Among 69 depressed patients 38 mild, 28 moderate, and 3 severe ranges were noted. Among 75 patients with anxiety, 52 mild, 18 moderate, and 5 severe ranges were noted. The age of the patient does not show a major difference in the development of depression and anxiety. PCOS women who married and have children (n=45) were mostly affected with depression (n=39) and anxiety (n=43). Menstrual irregularity in PCOS patients with depression and anxiety is majorly seen among those who have last menstrual between 30–60 d. Middle-income patients were affected by depression and anxiety greatly, according to this study. Conclusion: We conclude that the prevalence rate of depression and anxiety is greater in PCOS patients.

Design, Docking, Characterisation, and Synthesis of Pyrimidine Derivatives for Antidepressant Activity.

According to the report, in 2022, the prevalence rate of depression in India was 4.50%, and the cases stood at 56,675,969. The development of antidepressant agents has reduced the number of depressant and suicidal cases. Many researchers have found that pyrimidine possesses antidepressant activity. With this background, we thought of synthesizing pyrimidine derivatives. The objective of this study is to carry out molecular docking, synthesis, characterization, and evaluation of 2-((4,6-diphenylpyrimidin-2-yl)oxy)-N-phenylacetamide derivatives (17-26) as in vivo antidepressant agent. The designed compounds were checked for their activity using Molegro virtual docker (MVD) and were further synthesized. Benzaldehyde reacted with acetophenone to give compound (3), which gave compound (4) upon reaction with urea. In another reaction, substituted anilines (5) were reacted with chloroacetyl chloride (6) to yield compounds (7-16), which upon further reaction with compound (4) yielded the final derivatives (17-26). The synthesized compounds were characterized by spectral analysis and checked for their antidepressant activity. The MolDock scores of the derivatives ranged from -147.097 to -182.095, whereas of active ligand IXX_801 was -115.566. All the synthesized pyrimidine derivatives showed better affinity towards the Cryo-EM structure of the wild-type human serotonin transporter complexed with vilazodone, imipramine, and 15B8 Fab protein (PDB ID: 7LWD) as compared to standard drug clomipramine (-101.064). All the synthesized derivatives were screened for antidepressant activity at a 100mg/kg dose level compared to the standard clomipramine HCl at a dose level of 20mg/kg. Among all the synthesized derivatives, compound 24 showed the most potent antidepressant activity, and Compound 20 showed moderate antidepressant activity, which reduced the duration of immobility times to 35.42% and 31.97% at 100mg/kg dose level when compared to the control, respectively. Compound 24 showed the highest MolDock score as well as found to be the most potent antidepressant agent.

Psychological distress among low-vision patients

Purpose: The purpose of the study was to measure the mental well-being of patients suffering from low vision using the Depression, Anxiety, and Stress Scale (DASS). Methods: Low-vision patients who visited the low-vision clinic of CL Gupta Eye Institute were studied using the DASS. Patients were excluded if they were &lt;18 years old or could not understand the questionnaire due to an intellectual disability. Sociodemographic characters (such as age, gender, marital status, and education) were recorded before the administration of the study questionnaire. Results: In this study of 60 low-vision patients, high rates of psychological distress were observed, with 85% experiencing depression, 81.7% anxiety, and 75% stress. Demographic variables such as age, gender, marital status, and education did not significantly affect these rates. However, individuals with severe visual impairment (VI) or blindness had significantly higher prevalence rates for depression (P = 0.003), anxiety (P = 0.001), and stress (P = 0.013). Conclusion: This study reveals a high prevalence of depression, anxiety, and stress among low-vision patients, with the most pronounced impact seen in individuals with severe VI or blindness. These findings underscore the urgent need for targeted mental health interventions to improve the well-being of low-vision patients, especially those with severe VI. Tailored support can significantly enhance their overall quality of life and psychological health.

Prevalence, Patterns and Peculiarities of Depression among Tuberculosis Patients Attending Directly Observed Treatment Short-course (DOTS) Centers in Lagos State Nigeria

Tuberculosis (TB) is an infectious disease that is life-threatening to vulnerable populations, and has been reported to be associated with depression. Nigeria is one of the countries with a high TB burden, and with the current economic hardship in Nigeria, people are becoming poorer suggesting more TB patients are more likely to elapse into depression. The aim of this research was to assess the prevalence, patterns and peculiarities of depression among TB patients attending Directly Observed Treatment Short course (DOTS) centers in Lagos State, Nigeria. A descriptive, cross-sectional survey was conducted among 301 TB patients at 8 DOTS centers in Lagos State, Nigeria using a two-stage sampling method. Data was collected using interviewer-administered questionnaires to elicit responses from the TB patients. Patient Health Questionnaire-9 (PHQ-9) was used to determine and assess depression. Data was analyzed using SPSS version 23.0, with the Chi-square test being used to check for the association between socio-demographic characteristics and depression among the respondents. Mean age of the respondents was 35.1±11.7 years. A majority (71.8%) of the respondents were males, 69.1% were Christians, Yorubas were most (52.2%), 88.4% earned ≤N150,000 monthly, and only 1 respondent had no formal education. The prevalence rate of depression among the TB patients was 51.8%. Socio-demographic characteristics like gender (females were more affected), low financial status, and low educational level were associated with depression (p&lt;0.05); unlike age, marital status, ethnicity, employment status, and family setting (p&gt;0.05). Depression among TB patients is real as one in every two TB patients is depressed. Therefore, healthcare workers at DOTS centers should pay adequate attention to signs of depression among their patients.

Understanding Mental Health Needs and Predictors of Anxiety in Emirati Female Students in Higher Education

The prevalence rates of depression, anxiety, and stress range between 5% to 70% globally. Many students experience these mental health conditions as they go through transitional periods in life, such as starting higher education. This study aimed to explore mental health concerns, specifically depression, anxiety, stress, and quality of sleep, in Emirati female university students, a topic that has been understudied in the Middle East. We used the Depression, Anxiety, and Stress Scales (DASS-21) and the Pittsburgh Sleep Quality Index (PSQI) to assess 23 bilingual (Arabic/English) female adolescent Emirati students in the UAE. The data was analyzed using a multiple regression analysis. We found that most participants had normal levels of depression and stress, but over 60% of them had moderate to severe anxiety symptoms. Additionally, a substantial majority reported poor sleep quality. Stress was a significant predictor of anxiety, explaining 53.3% of the variance in anxiety scores. Although other factors influence anxiety, stress seems to be a substantial contributor. This study investigates the pervasive issue of anxiety among adolescent Emirati female students, with stress emerging as a major contributing factor. The preliminary findings underscore the imperative for additional research. Our exploration provides a roadmap for a comprehensive evaluation of mental health concerns within this population, offering valuable insights into potential preventive and intervention strategies that warrant further investigation.

Prevalence of depression among older people in Iraq

Prevalence of depression among older people in Iraq

Prevalence of depression among older people in Iraq

Background: The global prevalence of mental disorders, including depression, has steadily increased. Objective: To identifying the prevalence rate of depression and the related predictors among old-age people in Iraq. Patients and Methods: A cross-sectional study was conducted from August to November 2021. A random sampling technique was employed to gather information from the old age patients during their routine visits to outpatient clinic of three public hospitals (Baquba, Ramadi, Samarra), in Iraq. Data collection involved the utilization of a semi-structured questionnaire incorporating the validated Geriatric Depression Scale (GDS-30) administered through face-to-face interviews. Descriptive, bivariate, and multivariate logistic regression analyses were employed to examine the relationships between variables in the study. SPSS version 16 was utilized for data analysis, with statistical significance set at a threshold below 0.05. Results: Data of 344 old-age respondents (range 60-81 years) with a mean age of 75.15 (± 7.52) years have undergone final analysis. More than half were males (50.6%), married (62.2%), ranked themselves as unhealthy (72.4%), physically inactive (70.6%), and financially dependent (71.8%). The overall prevalence of depression was 74.4%. Logistic regression revealed significant associations: elderly females had 3.805 times higher risk (P&lt;0.001,95% CI: 1.999 to 5.241), unhealthy individuals had 2.379 times (P&lt;0.001, 95% CI 1.657 to 3.415), limited activities of daily living (ADL) had 2.650 times (P =0.001, 95% CI: 1.076 to 3.902), and those lacking family support had1.799 times (P = 0.003, 95% CI: 1.040 to 3.746) than their counterparts. Conclusion: High depression rates and multiple risk factors necessitate the urgent need for health and political intervention to support patients and promote greater social participation.

Prevalence of anxiety, depression, and post-traumatic stress disorder among Omani children and adolescents diagnosed with cancer: a prospective cross-sectional study

BackgroundChildren and adolescents diagnosed with cancer often experience psychological distress, encompassing anxiety, depression, and post-traumatic stress disorder (PTSD). This study aimed to evaluate the prevalence of these conditions among Omani children and adolescents diagnosed with cancer, alongside identifying contributing factors.MethodsA prospective cross-sectional study was conducted from October 2021 to June 2023 among a cohort of Omani children and adolescents (6–18 years old) diagnosed with cancer at three primary cancer referral centres in Oman. Validated Arabic-language versions of the Screen for Child Anxiety Related Disorders, the Center for Epidemiologic Studies Depression Scale for Children, and the Impact of Event Scale-Revised instruments were used to assess symptoms of anxiety, depression, and PTSD, respectively. An initial assessment (T1) was undertaken within the first 3 months of diagnosis, followed by a second assessment (T2) 3–6 months later.ResultsOf 113 eligible participants, 101 agreed to participate in the study (response rate: 95.6%), with 92 (91.0%) completing both assessments and included in the final analysis. Prevalence rates of anxiety, depression, and PTSD decreased from 43.5%, 56.5%, and 32.6%, respectively, at T1, to 38.0%, 35.9%, and 23.9% at T2. All average scores were below diagnostic cut-off points, except for the depression score at T1. Anxiety and depression scores decreased significantly (p = 0.043 and 0.001, respectively) between T1 and T2, as did the overall prevalence of depression (p = 0.004). At T1, linear regression analysis showed significant correlations between anxiety scores and the child’s age and PTSD score (p < 0.05); these variables were also correlated with depression scores (p ≤ 0.001). At T2, significant correlations were observed between anxiety scores and the child’s age and PTSD scores (p < 0.001). At both T1 and T2, anxiety, depression, and PTSD scores remained significantly correlated (p < 0.001).ConclusionsOmani children and adolescents recently diagnosed with cancer exhibit a high prevalence of anxiety, depression, and PTSD over time. Age-appropriate communication, ongoing support, and mental health services are recommended to help this patient group cope with their diagnosis and manage their emotional wellbeing. There is a need for future research to determine the effectiveness of specific psychological interventions in reducing the frequency of these disorders.

Mental health difficulties and health related quality of life amongst late adolescents in vocational education

This study investigated vocational students’ mental health by identifying the prevalence of depression, stress, anxiety, eating disorders and associated risk and protective factors among 16- to 18-year-old students attending a vocational college in Malta. Health Related Quality of Life (HRQOL) was also investigated. A sample of 422 students completed standardised self-report mental health tools and a demographic and personal variables’ questionnaire. A total of 64.4% of students were found to be struggling with at least one of the mental health conditions assessed while 36.7% reported a suspected eating disorder. The prevalence rates of depression, anxiety and stress (moderate, severe or extremely severe) were 43.3%, 48.8% and 29.3% respectively. Students had a lower HRQOL than the reference population as indicated by European norm data. Only 13.5% of participants sought help from mental health services. Risk factors include female gender, poverty, being LGBTQ, not living with both parents, past negative school experiences, poor relationships and presence of suspected or diagnosed conditions or disabilities, amongst others. Having supportive relationships with family, peers and school personnel emerged as protective factors.

Prevalence and social determinants of anxiety and depression among adults in Ghana: a systematic review and meta-analysis protocol

IntroductionAnxiety and depression pose a significant global health challenge, especially affecting adults in low-income and middle-income countries. In many low-income and middle-income countries, including those in sub-Saharan Africa, social determinants...

Natural history of depression up to 18 years after stroke: a population-based South London Stroke Register study

BackgroundCurrent evidence on the long-term natural history of post-stroke depression (PSD) is limited. We aim to determine the prevalence, incidence, duration and recurrence rates of depression to 18-years after stroke and assess differences by onset-time and depression severity MethodsData were from the South London Stroke Register (1995-2019, N=6641 at registration). Depression was defined using the Hospital Anxiety and Depression scale (scores>7=depression) at 3-months, then annually to 18-years after stroke. We compared early- (3-months post-stroke) vs late-onset depression(1-year) and initial mild (HADS scores >7) vs severe depression (scores >10) Findings3864 patients were assessed for depression at any time-points during the follow-up (male:55·4% (2141), median age: 68.0 (20·4)), with the number ranging from 2293 at 1-year to 145 at 18-years after stroke. Prevalence of PSD ranged from 31·3% (28·9-33·8) to 41·5% (33·6-49·3). The cumulative incidence of depression was 59·4% (95% CI 57·8–60·9), of which 87·9% (86·5-89·2) occurred within 5-years after stroke. Of patients with incident PSD at 3-months after stroke, 46·6% (42·1-51·2) recovered after 1 year. Among those recovered, 66·7% (58·0-74·5) experienced recurrent depression and 94·4% (87·5-98·2) of recurrences occurred within 5-years since recovery. Similar estimates were observed in patients with PSD at 1-year. 34·3% (27·9-41·1) of patients with severe depression had recovered at the next time-point, compared to 56·7% (50·5-62·8) with mild depression. Recurrence rate at 1-year after recovery was higher in patients with severe depression (52·9% (35·1-70·2)) compared to mild depression (23·5% (14·1-35·4)) (difference: 29·4% (7·6-51·2), P=0.003) InterpretationLong-term depressive status may be established by 5-years post-onset. Early- and late- onset depression presented similar natural history, while severe depression had a longer duration and quicker recurrence than mild depression. These estimates were limited to alive patients completing the depression assessment, who tended to have less severe stroke than excluded patients, so may be underestimated and not generalizable to all stroke survivors