Prevalence Of Tourette Syndrome Research Articles

Prevalence of Tourette syndrome among children and adolescents in the United States, 2016–2022

BackgroundTourette syndrome (TS) is a neurodevelopmental disorder. The prevalence of TS in 2016–2017 has been reported; however, little is known about the current prevalence and trend in children and adolescents with TS. This study aimed to estimate the prevalence and trend of Tourette syndrome (TS) among US children and adolescents aged 0–17 years from 2016 to 2022.MethodsWe analyzed data from a nationally representative sample of 278,472 children and adolescents aged 0–17 years who participated in the 2016–2022 National Survey of Children’s Health (NSCH), a nationwide, population-based, cross-sectional survey of US children and adolescents. TS was defined as the affirmative response in the questionnaire completed by a parent or guardian.ResultsAmong the 278,472 children and adolescents enrolled, 754 had been diagnosed with TS, with an overall prevalence of 0.23% in all children and adolescents aged 0-17 years. The weighted prevalence by age group was lower than 0.01% in children aged 0–2 years, 0.05% in children aged 3–5 years, 0.28% in children aged 6–11 years, and 0.38% in adolescents aged 12–17 years. There were significant sex and racial/ethnic differences in the overall prevalence of diagnosed TS (i.e., 0.35% in boys and 0.11% in girls, 0.22% in Hispanics, 0.28% in non-Hispanic whites and 0.16% in non-Hispanic blacks). There was no significant change in the estimated prevalence of TS from 2016 to 2022.ConclusionBased on nationally representative data, this study found that the national prevalence of TS among the US children and adolescents differed by sex and race/ethnicity but remained stable from 2016 to 2022.

Incidence and prevalence of Tourette syndrome and chronic tic disorders in Taiwan: a nationwide population-based study

The incidence of Tourette syndrome and chronic tic disorders has seldom been evaluated in Asia. Using the National Taiwan Insurance Research Database, the annual standardized incidence and prevalence of Tourette syndrome (TS) and chronic tic disorders were estimated from 2007 to 2015. The pre-existing comorbidity at disease diagnosis was also evaluated. From 2007 to 2015, the age- and sex-standardized incidence increased from 5.34 (95% confidence interval [CI] 5.06-5.62) per 100,000 person-years to 6.87 (95% CI 6.53-7.21) per 100,000 person-years. In children and adolescents, the age- and sex-standardized incidence increased from 19.58 (95% CI 18.42-20.75) per 100,000 person-years to 31.79 (95% CI 30.09-33.49) per 100,000 person-years. In adults, the age- and sex-standardized incidence decreased from 2.01 (95% CI 1.79-2.23) per 100,000 person-years to 1.24 (95% CI 1.07-1.42) per 100,000 person-years. The incidence rate ratio (IRR) between males and females was 3.74 (95% CI 3.32-4.22). The age- and sex-standardized prevalence increased from 37.51 (95% CI 36.75-38.27) per 100,000 people in 2007 to 84.18 (95% CI 83.02-85.35) per 100,000 people in 2015. The rate risk (RR) between males and females was 3.65 (95% CI 3.53-3.78). The annual incidence rates of TS and chronic tic disorders increased in childhood and adolescence but decreased in adulthood from 2007 to 2015. The prevalence rates increased over the same period.

The Prevalence of Tourette Syndrome and Other Tic Disorders in Saudi Arabia

Background: Tic disorders (TD), including Tourette syndrome, are considered as one of the prevalent neurological conditions across the world which affects pediatric population. Tourette syndrome (TS), also called Gilles de la Tourette syndrome or Tourette disorder, a clinical subtype of TD with the most severe and persistent symptoms, is a complex multifaceted neurodevelopmental disorder characterized by multiple motor and at least one phonic tic starting before the age of 18 and lasting for at least 1 year.
 Objectives: Our study is designed to assess the prevalence of Tourette syndrome and other tic disorders among Saudi population and examine the sociodemographic factors including age, sex, education, and birthplace.
 Methods: A cross-sectional survey study conducted in Saudi population. An online questionnaire utilized to collect information from the population via various social media applications. The required minimum sample size is determined to be 384 participants. For statistical analyzation, the Statistical Package of Social Science Software (SPSS) program, version 20 (IBM SPSS Statistics for Windows, Version 20.0. Armonk, NY: IBM Corp.) was used.
 Results: The study sample consisted of 2793 participants, 73% of them were females and 27% were males. 43.6% aged between 20- 30 years old and 33.4% aged less than 20 years old. 9.7% of participants suffer from Tourette syndrome while 5.7% of participants have a child who suffer from Tourette syndrome. Regarding co-morbid diseases, 23.7% suffer from anxiety disorder, 16.7% have sleeping disorder, 16.2% have depression, 10.8% eating disorder and 9.9% have obsessive-compulsive disorder. As for children with Tourette syndrome, 20.3% suffer from anxiety disorder, 19.5% have sleeping disorder, 18% have attention deficit hyperactivity disorder, 13.5% eating disorder and 7.9% have obsessive-compulsive disorder.
 Conclusion: Prevalence of TS among adults and children is higher than reported in previous figures. TS is associated with psychological and neurological diseases especially among children. TS should no longer be considered merely a motor disorder and, most importantly, that TS is no longer a unitary condition, as it was previously thought. Clinical assessment of children with chronic tic disorders warrants examination of other problems such as ADHD, disruptive behavior and anxiety.

Association of Epilepsy and Tourette Syndrome in Children

Epilepsy is increasingly recognized as an important association with tic disorders and Tourette syndrome in children. Previous studies reported the overall prevalence of Tourette syndrome was around 1% in children. Epidemiological studies showed evidences of increased neuropsychiatric comorbidities of Tourette syndrome including attention-deficit hyperactivity disorder, obsessive-compulsive disorder and autistic spectrum disorder. The recent studies have demonstrated that increased risk of epilepsy in children with Tourette syndrome, and also increased risk of Tourette syndrome in epilepsy children. The genetic and clinical information refer to a common neurobiological basis for epilepsy and Tourette syndrome.

The prevalence of diagnosed tourette syndrome in Canada: A national population-based study.

The objective of this study was to examine: (1) the prevalence of diagnosed Tourette syndrome in Canada by sex in youth (aged 12-17) and adults and (2) socioeconomic factors in this population. The majority of epidemiological studies of tics have focused on children and youth, with few studies describing the prevalence of tics in adult populations. Canadian data on Tourette syndrome prevalence were derived from the Canadian Community Health Survey 2010 and 2011 cycles, a Statistics Canada population-based cross-sectional survey that collects information related to health status. We determined the prevalence of diagnosed Tourette syndrome and examined sociodemographic factors, including age, sex, education, income, employment, and birthplace. Overall, 122,884 Canadians participated in the surveys, with 122 participants diagnosed with Tourette syndrome. The prevalence of Tourette syndrome was higher in males in youth: 6.03 per 1000 (95% confidence interval: 3.24-8.81) in males versus 0.48 per 1,000 (95% confidence interval: 0.05-0.91) in females, with a prevalence risk ratio of 5.31 (95% confidence interval: 2.38-11.81). In adults, the prevalence of Tourette syndrome was 0.89 per 1,000 (95% confidence interval: 0.48-1.29) in males versus 0.44 (95% confidence interval: 0.16.0-0.71) in females, with a prevalence risk ratio of 1.93 (95% confidence interval: 1.21-3.08). After adjusting for age and sex, adults with Tourette syndrome had lower odds of receiving postsecondary education or being employed and higher odds of having income lower than the median and receiving governmental support. Data on the prevalence of Tourette syndrome in adults are scarce because most studies focus on children. Our data demonstrate a decreasing prevalence risk ratio for sex in adults compared to children. A diagnosis of Tourette syndrome is associated with lower education, income, and employment in adulthood. © 2016 International Parkinson and Movement Disorder Society.

The Prevalence of Tourette Syndrome in Canada: A National Population-Based Study (P1.047)

The Prevalence of Tourette Syndrome in Canada: A National Population-Based Study (P1.047)

Researching Tourette syndrome in Europe.

Gilles de la Tourette syndromewas first described in Europe by the Parisian school of Jean-Martin Charcot in the second half of the XIX century. In 1885, French physician Georges Albert Edouard Brutus Gilles de la Tourette (1857–1904), one of the most pre-eminent figures in Charcot’s neuropsychiatry school, published a case series of nine patients who presentedwith the clinical triad of tics, echolalia and coprolalia. It was Charcot himself who named the condition after Gilles de la Tourette, securing eponymic (hence immortal) fame to his flamboyant pupil. As a medical condition, Gilles de la Tourette syndrome has a fascinating history on its own. Long considered to be a rare, somewhat bizarre medical curiosity, it progressively shifted towards the concept of a relatively common disorder, which in its milder forms can be regarded as a variant of healthy human behaviour. Recent estimates suggested that the prevalence of Tourette syndrome (or TS – as it is now called, especially in the American literature) can be as high as 1% in school-age children, if diagnosed according to current diagnostic criteria. Most importantly, TS’ unique position at the interface between neurology and psychiatry has attracted the interest of scholars and researchers, which devote their efforts to improve our understanding of the causes and effects of this fascinat-

Çocuk Ve Ergenlerde Tik Bozuklukları: Klinik Ve Etyolojik Bir Bakış / Tic Disorders In Children And Adolescents: A Clinical And Etiological View

Tic disorders which involve sudden and repetitive movements, gestures, or vocalizations form a spectrum ranging from simple transient tic disorders to more severe tic disorders that may cause significant impairment in psychosocial development, self esteem, family and social relationships, or academic/career performance. Around 6-20% of children experience simple transient tic disorder, while the prevalence of Tourette Syndrome (TS), a more severe tic disorder, is 5 to 6 cases in 1000 children. The severity and frequency of tics may change over time: usually peaking at the beginning of the second decade of life and diminishing towards the end of puberty. Psychosocial stressors, genetic and epigenetic factors and the interactions between these factors are involved in the etiology of tic disorders. In recent years, with the understanding of the suitability of TS as a model in investigating the interaction between genetic and environmental risk factors, increasing number of researches have been conducted in that direction.

Prevalence of Tourette Syndrome and Chronic Tics in the Population-Based Avon Longitudinal Study of Parents and Children Cohort

ObjectiveRecent epidemiologic studies have demonstrated that Tourette syndrome (TS) and chronic tic disorder (CT) are more common than previously recognized. However, few population-based studies have examined the prevalence of co-occurring neuropsychiatric conditions such as obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD). We evaluated the prevalence of TS, CT, and their overlap with OCD and ADHD in the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort.MethodA total of 6,768 children were evaluated using longitudinal data from mother-completed questionnaires. DSM-IV-TR diagnoses of TS and CT were derived using three levels of diagnostic stringency (Narrow, Intermediate, and Broad). Validity of the case definitions was assessed by comparing gender ratios and rates of co-occurring OCD and ADHD using heterogeneity analyses.ResultsAge 13 prevalence rates for TS (0.3% for Narrow; 0.7% for Intermediate) and CT (0.5% for Narrow; 1.1% for Intermediate) were consistent with rates from other population-based studies. Rates of co-occurring OCD and ADHD were higher in TS and CT Narrow and Intermediate groups compared with controls but lower than has been previously reported. Only 8.2% of TS Intermediate cases had both OCD and ADHD; 69% of TS Intermediate cases did not have either co-occurring OCD or ADHD.ConclusionsThis study suggests that co-occurring OCD and ADHD is markedly lower in TS cases derived from population-based samples than has been reported in clinically ascertained TS cases. Further examination of the range of co-occurring neuropsychiatric disorders in population-based TS samples may shed new perspective on the underlying shared pathophysiology of these three neurodevelopmental conditions.

Prevalence and clinical correlates of tic disorders in a community sample of school-age children

To examine the prevalence, clinical characteristics and course of children with tics identified in a community sample. This was a three-stage study. At the age of 9 to 11, parents of 8,244 children born at Aarhus University Hospital Skejby between January 1990 and April 1992 were invited to complete a screening questionnaire about tics. One year later participating parents completed the Strengths and Difficulties Questionnaire (SDQ). From December 2004 to June 2005, when the cohort was 13-15 years of age, parents of the children who screened positive for tics were interviewed in detail about tic disorders. The prevalence of Tourette Syndrome (TS) was 0.6 and 0.6% of chronic motor tics (CMT). Approximately one-third of those with a chronic tic disorder [CTD (TS and CMT)] reported remission of tics by age 13-15. On the parent-rated SDQ children with a CTD were five times more likely (OR = 5.0, 95% CI = 2.6-9.2) to fall into the clinical range of hyperactivity, twice as likely (OR = 2.2, 95% CI = 2.1-7.5) to exhibit disruptive and defiant behavior and over four times more likely to have emotional difficulties (OR = 4.7, 95% CI = 2.5-8.6) compared to children without tic disorders. Children with hyperactivity and CTD were more impaired than subjects with CTD only. Children with CTD and hyperactivity show greater symptom severity across several domains of behavior and overall impairment. In the absence of hyperactivity, children with CTD are at increased risk for emotional difficulties, but not disruptive behavior problems.

Tics et syndrome de Gilles de la Tourette : diagnostic, évolution et principes de traitement

The term "Tourette syndrome" designates the combination of tics with other symptoms. Gilles de la Tourette disease is one of its most frequent causes. It combines motor and vocal tics, with no identifiable cause, with self-mutilation and variable psychiatric comorbidity that may include obsessive-compulsive disorder (OCD) and other anxiety disorders, mood and personality disorders, and a syndrome of hyperactivity with attention disorders. The prevalence of Tourette syndrome is estimated at 0.1-1% of the general population. The condition begins during childhood and develops in a succession of periods of relative aggravation and remission of the tics. Most patients show improvement at the end of adolescence, but symptoms can persist into adulthood in approximately one third of patients. The cause of Gilles de la Tourette disease is unknown, but the role of genetic susceptibility has been suggested together with dysfunctions of the dopaminergic system and of neuron networks in associative and limbic areas of the basal ganglia and the prefrontal cortex. Treatment of Tourette syndrome and severe tics is often difficult and requires a multidisciplinary approach (neurologist, psychiatrist, psychologist and social workers). In mild forms, information and psychological management are usually recommended. Drug treatments--including neuroleptics--are essential in the moderate to severe forms of the disease. Psychiatric comorbidities, when present, often justify specific treatment. For the most severe forms of Gilles de la Tourette disease, preliminary results of treatment by deep brain stimulation of the associative and limb areas of the thalamus or pallidum have produced real hope of treatment, but nonetheless require confirmation.

The prevalence of Tourette syndrome in 13-14-year-olds in mainstream schools.

This study's aim was to estimate the prevalence and describe the clinical characteristics of Tourette syndrome (TS) in 13-14-year-old schoolchildren attending mainstream secondary schools. A three-stage ascertainment procedure was used to identify those who had TS. First, all 1012 Year 9 pupils were screened for tics using validated self-report questionnaires, which were completed by parents, teachers, and pupils. Data were available from at least one informant for 918 (90.7%) subjects. Tics were identified in 189 (18.7%) pupils. Second, families were contacted and a semistructured interview was carried out to determine whether they had TS. Finally, to ensure that the diagnosis of TS was correct, all those assessed as having TS were systematically assessed by an expert clinician in the field of TS. Seven young people were identified as fulfilling the criteria for TS, giving a minimum prevalence rate amongst 13-14-year-olds of 0.76% (95% CI 0.31 to 1.57) and a more realistic estimate of 1.85% (95% CI 1.00 to 2.95). Behavioural problems, in particular hyperkinetic disorder, were frequently associated with the TS group. These findings lend further support to the contention that the prevalence of TS in the community has hitherto been underestimated, though the symptoms may be generally milder than cases of TS presenting to clinics. This study supports the need for vigilance for TS in school-age children in primary care and in educational settings, so that children with this potentially serious disorder can be identified and assessed and effective management packages can be formulated to address their needs, when necessary.

‘Prevalence of Tourette syndrome in a mainstream school population’

Developmental Medicine & Child NeurologyVolume 40, Issue 12 p. 847-847 Free Access ‘Prevalence of Tourette syndrome in a mainstream school population’ Lionel Traverse MD, FRCP FAAP, Lionel Traverse MD, FRCP FAAP Clinical Assistant Professor, UBC Department of Paediatrics Medical Director Child Development Center 34081 Cyril Street Abbotsford BC V2S 2E8 CanadaSearch for more papers by this author Lionel Traverse MD, FRCP FAAP, Lionel Traverse MD, FRCP FAAP Clinical Assistant Professor, UBC Department of Paediatrics Medical Director Child Development Center 34081 Cyril Street Abbotsford BC V2S 2E8 CanadaSearch for more papers by this author First published: 12 November 2008 https://doi.org/10.1111/j.1469-8749.1998.tb12365.xCitations: 4AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article.Citing Literature Volume40, Issue12December 1998Pages 847-847 ReferencesRelatedInformation

Tourette Syndrome Prevalence

The prevalence of Tourette syndrome in a mainstream school population (ages 13 to 14 years) in West Essex, England has been determined by parent, teacher, and pupil questionnaires, class observations to identify tics, and subject and parent face-to-face interviews, and reported from the Section of Epidemiology and General Practice, Institute of Psychiatry, Denmark Hill, London, UK.