Prevalence Of Recurrent Aphthous Stomatitis Research Articles

Prevalence of recurrent aphthous ulcers among dentistry students and its association with anxiety

Objective: Recurrent aphthous stomatitis (RAS) is a common ulcerative inflammatory condition of the oral mucosa. Considering the contradictory findings of previous research about the association between anxiety and RAS, the present study aimed to determine the prevalence of RAS and its association with anxiety among dentistry students.
 Methods: In this descriptive-analytical study, a total of 241 dentistry students of G. University were divided into two groups (those with a history of RAS and healthy subjects) after recording their demographic and required information. Also, Cattell’s questionnaire was used to evaluate the level of anxiety. The results were analyzed using SPSS v.21 software, and a p-value of <0.05 was considered statistically significant.
 Results: 2.40% of subjects suffered from RAS. This condition was more prevalent in winter, and its incidence was significantly different between the two groups in terms of the presence of a family history of RAS (p=0.01), food allergy (p=0.05), and regular exercise (p=0.040). Subjects with RAS had a significantly higher anxiety intensity in the areas of lack of ego strength, superego susceptibility, and ergic tension compared to subjects without RAS (p<0.0001).
 Conclusion: The results showed that some areas of anxiety, including lack of ego strength, can be predictors of RAS. Therefore, teaching life skills such as anxiety management and its timely diagnosis and treatment can play an essential role in the prevention and treatment of RAS.

Prevalence and distribution of recurrent aphthous stomatitis in 10-13 years old: observational study in elementary school

ABSTRACT Introduction: Recurrent aphthous stomatitis (RAS), better known as canker sore, is the most common soft tissue disease of the oral cavity and affects 5 to 66% of the world’s population. RAS often begins in childhood and the age group of 10-14 years has the highest proportion of RAS in children. The purpose of this study was to determine the prevalence and distribution of RAS according to gender and age, clinical characteristics, ulcer location, and predisposing factors in 10 to 13 years old students. Methods: This observational study used cross-sectional design with total sampling method. The data were collected by oral cavity examination using direct observation with a mouth mirror and by filling out 10 closed questions questionnaires about predisposing factors of RAS. The data that had been obtained was tabulated and presented in tabular form using SPSS 16.0. Results: With a total sample size of 79 students from 10-13 years old, this study showed that the prevalence of RAS was found in 16 students (20,25%). The distribution of RAS based on gender was found to be higher in females (11,39%), while based on age, it was found that 11 years of age was the age that suffered the most RAS (10,13%). Based on clinical examination, all of the subjects were categorized as minor, mostly found at labial mucosa and tongue (31,25%). Based on questionnaires, the highest predisposing factor was due to trauma in 11 people (68,75%). Conclusion: In our study, among 10 to 13 year old students with RAS, females were mostly found at 11 years of age, detected with minor clinical characteristics. The labial mucosa and tongue, and trauma were the highest predisposing factors.KEYWORDS: recurrent aphthous stomatitis, children, prevalence, distribution

Otorhinolaryngological Manifestations and Esophageal Disorders in Celiac Disease: A Narrative Review.

Celiac disease (CeD) is a chronic gluten-sensitive immune-mediated enteropathy characterized by numerous intestinal and extra-intestinal signs and symptoms. Among extra-intestinal manifestations, otorhinolaryngological (ORL) complaints in CeD are relatively rare and their relation to CeD is frequently overlooked by physicians. Recent studies underlined that the prevalence of recurrent aphthous stomatitis, aphthous ulcers, geographic tongue, and xerostomia was significantly increased in CeD patients compared with healthy individuals. However, data about the other oral manifestations of CeD, such as atrophic glossitis, glossodynia, angular cheilitis, and salivary abnormalities, are scanty. Further ORL conditions associated with CeD include sensorineural hearing loss, nasal abnormalities, and obstructive sleep apnea. Moreover, several esophageal disorders such as gastroesophageal reflux disease and eosinophilic esophagitis have been associated with CeD. The pathophysiological link between both ORL and esophageal manifestations and CeD might be further investigated. In addition, also the role of gluten-free diet in improving these conditions is largely unclear. Certainly, otorhinolaryngologists can play an important role in identifying people with unrecognized CeD and may help prevent its long-term complications. The aim of this narrative review is to analyze the latest evidence on the association between CeD and ORL and esophageal manifestations.

ASSOCIATION BETWEEN CAFFEINE, ANXIETY AND THE OCCURRENCE OF APHTHOUS STOMATITIS IN THE ARMENIAN ETHNICITY

Abstract Introduction: Aphthous stomatitis is a recurring oral ulceration condition that affects a significant proportion of the population. While several factors have been proposed to contribute to its occurrence, the link between caffeine consumption, anxiety levels, and the development of aphthous stomatitis remains unknown. This survey-based study aimed to understand the association between coffee, anxiety, and the development of aphthous stomatitis in this specific demographic, which can provide useful insights for medical management as well as preventive strategies. Material and methods: A structured online questionnaire was distributed via various social media platforms targeting a sample of the Armenian population. The questionnaire collected information on participants’ demographics, coffee use patterns, anxiety levels as measured by perceived stress scales, and the occurrence of aphthous stomatitis. Statistical analyses, including Kendall’s tau, were carried out to investigate the relationships. Results: The results revealed a significant negative association between caffeine consumption and the occurrence of aphthous stomatitis among Armenian individuals Kendall’s tau-b (τb) correlation - 240* (p<0.05). Participants who reported regular caffeine consumption, such as coffee, tea, and energy drinks, had a lesser prevalence of aphthous stomatitis than non-consumers. Furthermore, Armenians in the survey showed that the majority (83.5%) had a low to moderate stress level. Conclusion: The data we collected in our research indicate that the prevalence of Recurrent Aphthous Stomatitis in the Armenian ethnicity was infrequent; over half of the participants didn’t report Recurrent Aphthous Stomatitis in the past 12 months. Which may correlate to their caffeine consumption habits, which can lead to stress reduction.

Prevalence of Recurrent Aphthous Stomatitis among Children Studying at Public Elementary Schools in Sari County in 2019

Introduction: Recurrent aphthous stomatitis (RAS) is a painful condition regarded as one of the most prevalent oral mucosal lesions. Few studies have been conducted to investigate the prevalence of this disease in Iranian children. Therefore, this study aimed to assess the prevalence as well as the risk factors of RAS among children attending public elementary schools in Sari County. Material and Methods: In the current descriptive-analytical cross-sectional study, a total number of 2399 elementary students attending public schools in Sari were examined. Of which 1780 of them completed the procedure and filled out a questionnaire about to their demographic and RAS related features. Data were analyzed using SPSS 24. Results: Although 32.8% of the population reported a previous history of RAS, the prevalence of this disease was 9.2% at the time of examination. RAS was significantly more frequent in boys compared to girls; however, the history of RAS was reported more in girls. In the present study, the prevalence of RAS was not significantly associated with age, social status, and economic status of the samples. Conclusion: Based on these findings, RAS appears to be a relatively common disease. As a result, providing families with appropriate training and basic healthcare seems to be effective.

THE RELATIONSHIP BETWEEN STRESS AND RECURRENT APHTHOUS STOMATITIS AMONG STUDENTS OF THE DENTISTRY FACULTY OF LAMBUNG MANGKURAT UNIVERSITY

Background: Recurrent aphthous stomatitis (RAS) is a yellowish-white ulcer-shaped lesion in the oral mucosa. The prevalence of RAS is estimated to be 20% of the world population. Based on Basic Health Search Indonesia in 2018, the prevalence of RAS was 8% of all oral health problems in Indonesia. Stress is one of the risk factors for recurrent aphthous stomatitis. Someone who is stressed will experience a decrease in the immune system, resulting in tissue destruction in the oral cavity. Purpose: To analyze the relationship between stress and RAS in Faculty of Dentistry, Lambung Mangkurat University students. Methods: This is analytical observational research with a cross-sectional study design. The study used a simple random sampling technique with a total sample of 57 co-assistants of the Dentistry at Lambung Mangkurat University. RAS was examined using a questionnaire, and the stress level was measured using the Perceived Stress Scale (PSS) questionnaire. The results of the study were analyzed using the chi-square test. Results: The result shows that the stress level suffered by the respondents is mainly in the moderate category, with a percentage of 44%. In comparison, the incident of RAS with positive results is mainly experienced by respondents with a percentage of 70.18%. The analysis using the chi-square test showed a significant relationship between stress and SAR with a significance value of 0.01 (p <0.05). Conclusion: The higher the stress level experienced will increase the risk of developing SAR.

Management of Recurrent Aphthous Stomatitis: An Indian Expert Consensus.

Recurrent aphthous stomatitis (RAS) is characterized by painful, oral mucosal ulcers with wide range of prevalence ranging from 2 to 78%. Etiology of RAS is idiopathic and multifactorial. There are numerous gaps in assessment and management of RAS and the absence of guidelines or a consensus document makes the treatment further difficult.The aim of this document is to provide an Indian expert consensus for management of RAS. Experts from different specialties such as Otorhinolaryngology, Oral Medicine/Dentistry and Internal Medicine from India were invited for face to face and online meetings. After a deliberate discussion of current literature, evidence and clinical practice during advisory meetings, experts developed a consensus for management of RAS. We identify that the prevalence of RAS may lie between 2 and 5%. In defining RAS, we advocate three or more recurrences of aphthous ulcers per year as criterion for RAS. Investigation should include basic hematological (complete blood count) and nutritional (serum vitamin B12, and iron studies) parameters. Primary aim of treatment is to reduce the pain, accelerate ulcer healing, reduce the recurrences and improve the quality of life. In treating RAS, initial choice of medications is determined by pain intensity, number and size of ulcers and previous number of recurrences. Topical and systemic agents can be used in combination for effective relief. In conclusion, this consensus will help physicians and may harmonize effective diagnosis and treatment of RAS.

Prevalence of recurrent aphthous stomatitis in a family medical office, Manzanillo, Cuban. A cross-sectional study

Recurrent Aphthous Stomatitis, also known as aphthous ulcers or simply aphthous, is considered the most common of oral mucosal lesions. To describe the prevalence of recurrent aphthous stomatitis. Descriptive, cross-sectional and prospective study. 847 patients who attended the Family Medical Office No. 28, San Francisco comunity, Manzanillo, from July 1, 2021 to June 30, 2022, Cuba, were evaluated. A calibrated and trained assistant investigator evaluated the following variables: Clinical classification of recurrent aphthous stomatitis (minor aphthosis, major aphthosis, or aphthosis herpetiformis), lesion pain intensity, lesion location, and risk factors (viral infection), bacterial infection, immunological alterations, psychosomatic alterations, oral trauma, gastrointestinal alterations, endocrine factors, allergic conditions, heredity, blood and nutritional deficiencies, smoking), age group, sex, race, and duration of the lesion. Aphthous stomatitis occurred in 30.46%, with greater frequency in the age group 30 - 39 years (24.42%). Minor aphthosis was the most frequent with 91.09%. The duration of the lesion of 10 to 12 days predominated with 37.60%, the most frequent location corresponded to the edge and tip of the tongue with 32.94% and the most representative pain intensity was mild with a total of 63.18%. The highest frequency among the risk factors corresponded to psychosomatic alterations with 100%. Recurrent Aphthous Stomatitis had a prevalence greater than 30% with a predominance of the female sex and young adults. Minor Aphtosis and a stay time of more than 10 days were the most frequent. The most common location is the tongue and bottom of the vestibular sulcus with the possible existence of a relationship between the mobile parts of the mouth. Stress, the main risk factor, exacerbated by Covid-19.

<strong> Correlation between presence of bacillus species and OHI-s in recurrent aphthous stomatitis patients </strong>

ABSTRACTIntroduction: The approximate prevalence of Recurrent Aphthous Stomatitis (RAS) was 45.42% at Gusti Hasan Aman Dental Hospital Banjarmasin. Bacillus sp. is a bacterium that can form spores that can be transmitted through air, dust, water and food. Poor oral conditions will increase the possibility of bacterial contamination, especially for ulcers found in RAS. This study aimed to analyzed correlation between the presence of Bacillus species and OHI-S in the oral ulceration of RAS patients. Methods: This was an analytical cross-sectional study conducted among Oral Medicine Department outpatients at Gusti Hasan Aman Dental Hospital, Banjarmasin, Indonesia. A total of 38 subjects were examined to assess Oral Hygiene Index Simplified and obtained bacteria samples using the swabs technique. Bacteria were then inoculated in blood agar base media and concurrently presented with gram staining. Bacteria were then identified using the catalase test, urease test, and oxidase test. Results: Bacillus species were predominantly identified in oral ulceration of RAS patients at Gusti Hasan Aman Dental Hospital Banjarmasin. Bacillus sp. (60,5%), Streptococcus sp. (34,2%), Neisseria sp. (2,6%), and Lactobacillus sp. (2,6%) were found in ulcerated RAS lesions. Spearman test resulted in p = 0.862 (p > 0.05), where no significant difference was obtained between presence of bacillus species and OHI-s in recurrent aphthous stomatitis patients. Conclusion: Bacillus species were predominantly identified in oral ulceration of RAS patients a. However, the presence of Bacillus sp. was not associated with OHI-S in RAS patients.Keywords: bacillus sp.; oral hygiene index simplified; recurrent aphthous stomatitis

Karakteristik Lesi dan Faktor-Faktor Pemicu Penderita Stomatitis Aftosa Rekuren pada Mahasiswa Profesi Kedokteran Gigi USU Tahun 2019-2020

Recurrent Aphthous Stomatitis (RAS) is ulcer in the oral mucosa that occur repeatedly with unknown etiologic factors but varied trigger factors and lesion characteristics. The prevalence of RAS still high in community, however pain and the recurrence impact the quality of life both in oral activities and daily activities such as: avoided brushing teeth that it causes poor oral conditions, impaired mastication, swallowing, speaking, feeling uncomfortable, difficulty sleeping and reducing social interaction. The purpose of this study was to determine the frequency distribution of lesion characteristics and the triggering factors for patients with recurrent aphthous stomatitis in USU dental professional students in 2019-2020. This research is a survey study with a cross sectional design. The population is students of the dental profession at the University of North Sumatra in 2019-2020 with a total sample of 62 respondents who were used as research subjects. Measurement of SAR variables using the Recurrent Aphthous Stomatitis Diagnosis (RASDX) questionnaire. The research data was obtained by distributing online questionnaires in the form of a google form. Students who were most affected by SAR were female at 87.1%. The most common type of SAR found was minor at 95.2%, was in the labial mucosa by 72.6%, single ulcers of 95.2%), history of ulcer duration suffered by respondents was around 7-14 days 54.8%, multifactorial triggering factors are genetic, trauma and stress (30,6%) with the most common triggering factor was stress at 93.5%. The characteristics RAS in this research were minor type on the labial mucosa, a single of number and duration of 7-14 days. Based on the trigger factors, it can be concluded that the most common group of 3 multifactor (genetic, trauma and stress) which stress is the most common factors.

Self-Reported Prevalence of Recurrent Aphthous Stomatitis among UiTM Dental Students

Recurrent aphthous stomatitis (RAS) is a common mucosal disease characterized by multiple recurrent, small, round, or oval ulcers with circumscribed margins, erythematous haloes, and yellow grey base. Although the exact etiology is unknown, various factors can trigger RAS development. Objectives: This study aims to determine the prevalence of self-reported RAS and to evaluate the associated risk factors of RAS among dental students. Material and methods: A set of validated questionnaires was distributed among the dental students in the Faculty of Dentistry, UiTM. The questionnaire comprises socio-demographic characteristics, nature of ulcers, risk factors, and treatment modalities. Data obtained from the questionnaire were analyzed using Chi-square statistical test SPSS version 27. Results: A total of 299 dental students participated in the questionnaire survey. The prevalence of RAS among dental students was 90.3 %. There was no significant relationship between the socio-demographic background of participants with self-reported RAS. The most common site affected was the buccal mucosa 64.1%, followed by the lips 55.2%. Risk factors frequently associated with RAS are injury (trauma) and stress 47.8% and 28.1%, respectively. Most dental students (69.3%) do not get any treatment to treat their ulcers, and only 1.5% seek treatment from the dentist. Conclusions: This study highlights the high prevalence of self-reported RAS among dental students and common risk factors reported associated with the occurrence of RAS. Therefore, this data assists the clinician in identifying common associated risk factors of RAS and subsequently improve management and efficient therapeutics.

Prevalence of recurrent aphthous stomatitis, oral submucosal fibrosis and oral leukoplakia in doctor/nurse and police officer population

BackgroundThe doctor/nurse and police officer population have some common typical characteristics of great professional pressure and night shift and past studies indicated oral mucosa lesions were closely associated with psychological factors and health-risking behaviors, however the prevalence of recurrent aphthous stomatitis (RAS) and the two commonly seen oral potentially malignant disorders of oral submucosal fibrosis (OSF) and oral leukoplakia in doctor/nurse and police officer in the Betel quid chewing city of Mainland China is unknown The cross-sectional study was to determine the prevalence differences of RAS, oral leukoplakia and OSF among doctor/nurse, police officer and non-doctor/nurse and non-police officer population aged 20–59 years.MethodsRAS, OSF and oral leukoplakia were examined in doctor/nurse group (male: 659, female: 2439), police officer group (male: 839, female: 262) and non-doctor/nurse and non-police officer group (male: 7576, female: 8129) from 2020-11-01 to 2021-08-31 in Health Management Center, Xiangya Hospital in Changsha city, Hunan province.ResultsThe prevalence rates of RAS, OSF, oral leukoplakia and oral leukoplakia combined with OSF in male and female non-doctor/nurse and non-police officer group are 8.32‰ and 10.83‰, 58.08‰ and 1.23‰, 11.75‰ and 0.25‰, 7.66‰ and 0.12‰ respectively. Compared with the non-doctor/nurse and non-police officer population, prevalence rates of RAS in male (24.27‰) and female (20.50‰) doctor/nurse population were significantly higher. Prevalence rates of OSF (21.24‰) and oral leukoplakia (3.03‰) in male doctor/nurse population were significantly less but prevalence rates of OSF (93.71‰), oral leukoplakia (20.17‰) and oral leukoplakia combined with OSF (15.42‰) for male police officer were significantly greater in comparison with male non-doctor/nurse and non-police officer group. OSF and oral leukoplakia prevalence rates were obvious lower for the female than the counterpart male group, but there were no significant differences of OSF and oral leukoplakia prevalence rates between the female non-doctor/nurse and non-police officer and female doctor/nurse group. Oral leukoplakia was not found in the female police officers.ConclusionsDoctor/nurse population have higher prevalence of RAS. Male doctors/nurses have lower prevalence of OSF and oral leukoplakia, while male police officers have higher prevalence of OSF, oral leukoplakia and oral leukoplakia combined with OSF.

Predisposing Factors for Recurrent Aphthous Stomatitis among Undergraduate Dental Students

Abstract Objectives The prevalence of recurrent aphthous stomatitis (RAS) among the general population worldwide is 20%. This study aims to discover any correlations between RAS predisposing factors and the gender and year of study of undergraduate dental students at the Faculty of Dental Medicine at Airlangga University. Methods A cross-sectional analytical study using simple random sampling was performed. The respondents answered seven questions on a self-reported online questionnaire set up using Google Forms. Chi-square analyses were conducted to determine any correlation between RAS predisposing factors and the gender and year of study of the students. Results The highest predisposing factors for RAS in undergraduate dental students were local trauma (77.7%) followed by stress (71.3%) and nutritional deficiencies (41.5%). Stress correlated strongly with the year of study (p = 0.015). There was no correlation between gender and RAS predisposing factors (p > 0.05). Conclusion There was a correlation between stress, one of the predisposing factors for RAS, and the year of study, but there was no correlation between gender and RAS predisposing factors including local trauma, stress, nutritional deficiency, genetics, allergies, and systemic diseases.

Evaluation of cinnamaldehyde mucoadhesive patches on minor recurrent aphthous stomatitis: a randomized, double-blind, placebo-controlled clinical trial

Background & objectiveThe use of herbal medicines to treat common oral diseases increases rapidly. Recurrent aphthous stomatitis is one of the most common oral mucosal diseases, which has an unclear etiology and could lead to severe pain and dysfunction. Cinnamaldehyde is a major component of cinnamon bark oil. Biological properties of cinnamaldehyde, such as antioxidant, antitumor, antifungal, cytotoxic, and anti-mutational characteristics, have been identified. Considering the prevalence of recurrent aphthous stomatitis and the importance of using herbal resources for treatment, the present study aimed to evaluate the effect of mucosal adhesive patches containing Cinnamaldehyde on minor recurrent aphthous stomatitis lesions.Material & methodsIn this randomized, double-blind clinical trial, patients were divided into two groups. The intervention group received three daily mucosal adhesive patches to be used in the morning, afternoon, and night. The control group also did the same with a placebo. To evaluate the healing and determine the diameter of the lesions, patients were clinically examined on days zero, 3, 5, and 7. The VAS scale evaluated pain at baseline and after each meal for seven days. The Fisher's exact test, t-test, Shapiro Wilk test, Friedman test, and the Mann–Whitney test were used to analyze the data using the SPSS 20 software.ResultsThere was no statistically significant difference in the mean diameter of the inflammatory lesion and pain intensity in the two groups in the baseline (p > 0.05). However, the ulcer size was significantly reduced in the cinnamaldehyde group on the third, fifth, and seventh days of the study. Except for baseline, the mean pain intensity significantly decreased in the cinnamaldehyde group compared to the placebo group (p < 0.05).ConclusionCinnamaldehyde mucoadhesive patches effectively reduced and improved aphthous lesions and pain intensity in patients and can be considered a treatment for RAS. Registration number: IRCT20180312039060N2—First registration date: 20/07/2018. The present study was registered as a retrospective study.

Assessment of Prevalence of Recurrent Aphthous Stomatitis in the North Indian Population: A Cross-Sectional Study.

Aim and Objective:The present study was undertaken for assessing the prevalence of recurrent aphthous stomatitis (RAS) in the North Indian population.Materials and Methods:Assessment of a total of 4255 patients was done over a period of 2 years, who came for a routine dental checkup. Recording of the complete demographic and clinical details of all the patients was done. The prevalence of RAS was assessed. Profile of patients with RAS was assessed separately. A pro forma was made and the type of treatment protocol followed by patients with RAS was also recorded. All the results were recorded in a Microsoft Excel sheet and were analyzed using SPSS software.Results:Analysis of a total of 4255 patients was done. RAS was found to be present in 800 patients. The overall prevalence of RAS was found to be 18.93%. Significant results were obtained when analyzing age, gender, and occupation as risk factors for RAS. Labial/buccal mucosa involvement occurred in 51.875% of the cases. In 44% of the cases, the size of the RAS was between 1 cm and 3 cm. Home remedy was followed in 17.875% of the cases.Conclusion:A significant proportion of patients in the North Indian population is affected by RAS. In comparison to males, females are more commonly affected.

Relationship between dietary factors and recurrent aphthous stomatitis in China: a cross-sectional study.

ObjectiveRecurrent aphthous stomatitis (RAS), a common oral mucosal disorder characterized by chronic, inflammatory, and ovoid ulcers, has a complex etiology. The purpose of the study was to investigate the specific dietary factors influencing the prevalence of RAS.MethodsA total of 754 participants aged 18 to 59 years were enrolled in this descriptive cross-sectional study. An anonymous questionnaire was adopted to investigate the distribution of RAS, dietary factors, self-reported trigger factors, and therapeutic methods.ResultsAmong all participants, the prevalence rate of RAS was 21.4%. Univariable analysis showed that fruit, dairy products, vegetables, and water, but not fried foods, fermented foods, spicy foods, and eggs, were preventive factors against RAS. After adjusting for age and sex, multivariable regression analysis suggested that fruit (adjusted odds ratio [aOR] = 0.430, 95% confidence interval [CI] = 0.218–0.847) and water (aOR = 0.294, 95% CI = 0.119–0.726) were protective factors against RAS.ConclusionThis study found that the consumption of fruit and water was negatively associated with RAS. These results imply a potential adjunctive and complementary role of food in RAS treatment and some feasible means of RAS prevention.

Helicobacter pylori and other factors in recurrent aphthous stomatitis: A cross-sectional study.

To evaluate the role of Helicobacter pylori and other risk factors in recurrent aphthous stomatitis (RAS). Patients with functional dyspepsia responded to questionnaires regarding demographic and clinical data, anxiety and depression, and a specific RAS questionnaire. They underwent upper digestive endoscopy and H.pylori evaluation. 476 patients were included and of the 372 evaluated for H.pylori, 65.6% were H.pylori-positive. RAS was reported by 32.6% (155/476). In the bivariate analysis of the 372 patients evaluated for gastric H.pylori status, positive subjects had a lower RAS prevalence (29.9%; 73/244) than H.pylori-negative (41.4%; 53/128) (p=.026). Smoking (p=.005) and older age (p=.034) were also associated with a lower prevalence, while female gender (p=.032) and lower income (p=.046) presented higher RAS prevalence. In the multivariate analysis, H.pylori infection (p=.017), smoking (p=.001), and older age (p=.013) were protective factors, while lower income (p=.030) and anxiety (p=.042) were risk factors. In the multivariate analysis of all patients, female gender, lower income, and more schooling years were risk factors. An unexpected lower prevalence of RAS was found in H.pylori-positive patients. Smoking, sex, age, income, education, and anxiety were associated with RAS.

Correlation of pain score with ulcer size in oral aphthous ulcers using 2% curcumin gel and 0.1% triamcinolone oral paste - A parallel comparison study

Background: Recurrent aphthous stomatitis (RAS) is a common inflammatory condition affecting the oral mucosa causing interference with mastication and speech with significant impact on quality of life. The use of topical steroids remains the mainstay as the primary therapeutic approach and they are often considered to be the first choice of treatment. Turmeric has been used in the Indian traditional medicine for centuries. Its anti-inflammatory and wound healing activities are demonstrated by the rapid healing of the ulcers. Aim: The primary aim of this study was to assess and correlate pain score with ulcer size using topical curcumin 2% gel and triamcinolone acetonide oral paste 0.12% in recurrent minor oral aphthous ulcerations. Methodology: Following convenient sampling, 60 volunteered students with oral aphthous ulcers were included to take part in this single-blinded randomised study. Randomization was done by flip coin method. Group I received Topical Curcumin oral gel 2% and Group II received Topical Triamcinolone acetonide 0.1%. Statistical Analysis: Qualitative data was expressed in percentage and quantitative in mean (SD). Independent sample t test and correlation was done. Results: The ulcer size was smaller initially and gradually increased in the next few days and the size decreased upon ulcer healing. Initially, the pain score was higher and gradually decreased as the ulcer healed. Positive correlation of ulcer size and pain score was obtained in Group I on the 1st day, 4th day and 5th day with statistical significance of P

Lifetime prevalence of recurrent aphthous stomatitis and its related factors in Northern Iranian population: The PERSIAN Guilan Cohort Study

Recurrent aphthous stomatitis (RAS) is one of the most prevalent oral inflammatory ulcerative lesions. The aim of this large population base study was estimated lifetime prevalence of RAS and its related factors among the Northern Iranian population. This study was conducted on 10,520 participants aged 35-70years based on the PERSIAN Guilan Cohort Study (PGCS). Prevalence proportions and multivariate logistic regression models were constructed for lifetime RAS prevalence using the SPSS software. Data on potential correlates of RAS including demographic profiles, lifestyle habits, and self-reported past medical histories were obtained. The lifetime prevalence of RAS was 8.3%. Multivariate logistic models showed that urbanization (adjusted odds ratio (AOR) = 1.2) and having a history of systemic disease, including rheumatic disease (AOR = 2.1), genital aphthous disease (AOR = 11.7), depression (AOR = 1.3), chronic headaches (AOR = 1.8), diabetes mellitus (AOR = 1.6), and epilepsy (AOR = 2), were independent predictors of RAS. In addition, smokers (AOR = 0.5) and individuals older than 50years of age (AOR = 0.8) were less likely to have a history of RAS. The lifetime prevalence of RAS among the Northern Iranian population was relatively low. It seems that predisposing factors, such as younger age, urbanization, and systemic disease, including rheumatic disease, genital aphthous disease, depression, chronic headaches, diabetes mellitus, epilepsy, and not smoking, could contribute to RAS prevalence.

Prevalence of Molar Incisor Hypomineralisation among School Children of Sari, Iran

Background and objective: Recurrent aphthous stomatitis (RAS) is a painful disease regarded as one of the most prevalent oral mucosal lesions. Few studies have been carried out to investigate the prevalence of this disease in children in Iran. Therefore, this study aimed to determine the prevalence of recurrent aphthous stomatitis among children studying at public elementary schools in Sari County (Iran), and to examine the factors affecting its prevalence. Materials and methods: This was a cross-sectional descriptive-analytical study. It had a statistical population including all students studying at public elementary schools in Sari County, Iran in 2019. Using the sample size determination formula, 1790 students were considered as the sample and were randomly selected from the public elementary schools in this county. The age range of the samples was 7 to 14 years old and their mean age was 10.05. Data were gathered by clinical examinations and a researcher-made questionnaire. The collected data were analyzed via SPSS ver. 24. Results: The prevalence of recurrent aphthous stomatitis was 32.8% concerning the samples’ history and it was 9.2% at the time of examination. Moreover, at the time of examination, its prevalence was significantly higher in the boys (10.9%) compared to the girls (7.6%). However, the history of RAS was reported more by the girls. In the present study, the prevalence of recurrent aphthous stomatitis was not significantly associated with age, social status, and economic status of the samples. Conclusion: Considering these results, it can be deduced that recurrent aphthous stomatitis is a relatively common disease. Accordingly, informing families by providing appropriate training and basic healthcare seems to be effective.