Prevalence Of Psychological Morbidity Research Articles

Prevalence of Psychological Morbidities Among Hospital Staff During the Second Wave of COVID-19 in India.

Prevalence of Psychological Morbidities Among Hospital Staff During the Second Wave of COVID-19 in India.

Psychological morbidities among spouses of men with type 2 diabetes mellitus and erectile dysfunction in a primary care setting.

Erectile dysfunction (ED) negatively affects patients' emotions. However, its effect on spouses' psychological well-being remains largely unknown. This study aimed to examine psychological morbidities and their associated factors among spouses of men with type 2 diabetes mellitus (T2DM) and ED. This cross-sectional study included 115 women recruited through their husbands who were patients at a selected government health clinic in Malaysia. A self-administered questionnaire containing the Depression Anxiety and Stress Scale-21 and items on health-related information, marital history, sexual history and perception of husband's ED was used to assess possible depression, anxiety and stress. The prevalence of psychological morbidities was 28.7% (depression=17.4%, anxiety=25.2% and stress=10.4%). Most respondents were middle-aged [median (interquartile range)=44.0 (11.0) years], were employed (55.7%) and had a low income (81.7%). About 47.0% of the spouses had a medical problem. The mean marriage duration was 18.7 (standard deviation=7.9) years. Almost all (90.4%) had sexual intercourse (SI) within the previous month. The majority had moderate-to-high interest in SI (72.2%) with a frequency of one to two times per week (69.6%). The majority (75.7%) did not perceive their husband as having ED. Multiple logistic regression demonstrated that medical illness was significantly associated with anxiety (adjusted odds ratio=2.85, 95% confidence interval=1.11-7.29, P=0.029). Psychological morbidities were present among the spouses of men with T2DM and ED. Psychological well-being was significantly affected by their medical illness. Despite their husband's ED, the women declared to have regular sexual relationships and did not perceive their husband as having erectile problems.

Magnitude and determinants of psychological morbidities among pregnant women: Results from a pregnancy cohort in rural Central India

BackgroundPsychological morbidities are one of the emerging global health problems. It affects a considerable number of ante-natal women leading to consequences during the postnatal period as well. We conducted this research to study the magnitude and determinants of psychological morbidities during pregnancy. MethodsIn this study, we included 650 pregnant women from an established cohort of 2500 pregnant women and assessed the psychological morbidities among them using the GMHAT/PC tool. ResultsThe overall prevalence of psychological morbidities during pregnancy was 14.6%, with anxiety and depression being the leading ones. Low education levels, lower socio-economic status, unintended pregnancy, complicated previous pregnancy, lack of family and social support, and domestic violence increased the odds of psychological morbidity. On Multivariate logistic regression, Low education levels increased the odds to more than twice [illiterate/primary schooling OR: 4.00, p = 0.026; secondary schooling OR: 2.64, p = 0.034; high school OR: 2.60, p = 0.033] unintended pregnancy [OR: 1.91, p = 0.043] and lack of family support [OR: 7.19, p < 0.001] increased the odds of psychological morbidity among pregnant women. ConclusionBringing these issues to the mainstream and addressing them by developing interventions to address them during the lifecycle of a female will help to prevent episodes of psychological stress and morbidity among pregnant females.

Occupational Health and Safety Receptivity towards Clinical Innovations That Can Benefit Workplace Mental Health Programs: Anxiety and Hypnotherapy Trends.

Anxiety is one of the most common mental health conditions experienced by people in Australia during their working years according to the Australian Bureau of Statistics (ABS) and employers recognising that mental health impacts their organisation’s bottom line are increasingly interested in programs to promote better mental health, well-being, and productivity. Beyond management concern for productivity, statutory protection is necessary to safeguard mental health, under the Australian Occupational Health and Safety (OHS) Act, organisations have a duty to eliminate or minimise risks to psychological (mental) health by designing effective workplace systems and Occupational Health and Safety (OHS) practitioners are central to the design and responsibility in managing these systems. Despite literature indicating the benefits of OHS workplace mental health initiatives, such as improved overall health, reduced absenteeism, increased job satisfaction and morale, there remains a lack of empirical research around program measurement, and their effectiveness in this area has been brought into question. The OHS function is interested in improving research around the relationship and connection between work performance and mental health but: there are few studies regarding performance outcomes of mental health OHS services within management journals and insufficient information around the prevalence of psychological morbidity in the workplace and its impact. The purpose of this study was to assess OHS perception regarding anxiety and reveal perceptions and receptivity towards alternative therapies and solutions being used in clinical practice to deal with anxiety such as cognitive behavioural therapy (CBT) with a focus on Hypnotherapy.

Coping styles to vitiate the risk of psychological morbidities among pre/para-clinical and clinical undergraduate medical students: a comparative cross-sectional study in India

BackgroundPsychological morbidities are high among undergraduate medical students. They experience the transition between pre/para-clinical and clinical training as a stressful period and cope differently. Research from India in this regard are lacking. The aim of this study is to assess and compare the prevalence of psychological morbidities, associated factors and coping styles between pre/para-clinical and clinical undergraduate medical students. This institution-based cross-sectional observational design study was conducted among pre/para-clinical and clinical group of undergraduate medical students (a total of 382) by using a questionnaire in the period between April and June 2021. Stratified random sampling technique was used to select the study participants. The survey included standard self-administered questionnaires like GHQ-28 and Lin-Chen’s coping inventory to assess psychological morbidities and coping styles, respectively. Associated factors for psychological morbidities, and coping styles between two groups, were compared using chi-square test, independent t-test and binary logistic regression analysis.ResultsOut of the 382 responders, psychological morbidities (GHQ-28 score > 23) were found in 61% participants. Both groups reported high level, a slightly higher preponderance in clinical (61.5%) than pre/para-clinical students (60.6%) and with nonsignificant difference of psychological morbidities. Compared to pre/para-clinical group, clinical group was found to have more substance consumption behavior (p < 0.001), dissatisfaction with academic performance (p < 0.001), sought psychiatric consultation (p < 0.004) and currently on psychiatric treatment (p < 0.04). Overall, coping was found to be average and good among the participants. Active problem coping behavior was more significantly used by pre/para-clinical group, while passive problem coping and passive emotional coping behaviors were positively significantly correlated with psychological morbidities in clinical group.ConclusionsThis study established a significant correlation between psychological morbidities and passive coping styles in clinical group. These students need interventions to encourage the use of more active coping styles during the training to provide advances in future career. A strong correlation with dissatisfied academic performance may be a call for an efficient and more student-friendly curriculum.

Assessment of depression, anxiety and stress experienced by health care and allied workers involved in SARS-CoV2 pandemic.

Introduction:The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) causing coronavirus disease 2019 (COVID-19) has led to a global health crisis. Health workforce has been working vigorously in COVID-19 management. So, we have planned this study with an aim to assess the psychological profile of healthcare and allied workers involved in SARS-CoV2 pandemic and to look for associated factors.Methodology:A cross-sectional observational study was planned at All India Institute of Medical Sciences, Patna. Study population comprised of Health care workers and allied health care workers involved in COVID-19 management.Results:Data from 254 study participants have been included in the study. The prevalence of severe and extremely severe depression among study participants was 8.3 and 3.1 percent. Severe and extremely severe anxiety prevalence was found to be 9.4 and 13.8 percent. The prevalence of severe and extremely severe stress was 2.4 and 2.4 percent each. Education till post-graduation, unmarried, occupation of doctor, Comorbidity of headache and occurrence of influenza-like illness in last 3 months had a statistically significant association with high depression score. With high Anxiety score and high-stress score statistically significant association was seen in education till postgraduation, unmarried, occupation of doctor, duration of 1 COVID-19 duty of ≥8 hours.Conclusion:The study highlights high psychological comorbidities in the form of depression, anxiety and stress among health care workers and allied health care workers working in COVID-19 pandemic. Prevalence of psychological morbidity is higher among doctors compared to nurses and allied health workers. COVID-19 duty of ≥8 hours have been found to be hampering mental health.

Comparison of prevalence of psychological morbidities, associated factors, and coping styles between pre/para-clinical and clinical undergraduate medical students: A rural institution-based cross-sectional study in a northern state of india

Comparison of prevalence of psychological morbidities, associated factors, and coping styles between pre/para-clinical and clinical undergraduate medical students: A rural institution-based cross-sectional study in a northern state of india

Anxiety, depression and harmful use of alcohol in severe chronic plaque psoriasis: A cross-sectional study

BackgroundPsoriasis is a common, chronic T cell–mediated disease characterised by erythematous, scaly plaques. Psoriasis is associated with depression, anxiety, poor quality of life, harmful use of alcohol and suicidal ideation. We performed this study to find out prevalence of psychological morbidity in our patients with severe psoriasis and to know clinical variables associated with higher risk of psychological morbidity. MethodThis study is a cross-sectional, observational study conducted in a dermatology outpatient department (OPD) of a tertiary care centre. Study population included patients with severe psoriasis area severity index (PASI>10). Clinical and epidemiological data, Patient health questionnaire-9, Generalised anxiety disorder-7, Dermatology life quality index (DLQI) and Alcohol Use Disorders Identification Test questionnaires were recorded. Data were analysed using SPSS, version 24. Chi-square test and Spearman's rank correlation test (ρ) were performed, and p value of <0.05 was considered statistically significant. ResultA total of 140 patients were included in the study and consisted of 67 men and 73 women. The median age was 44 years, median duration of disease was 10 years and median PASI was 13.6. Scoring revealed moderate-to-severe depression in 69 (49.3%) patients, moderate-to-severe anxiety in 40 (28.6%), severe impairment in quality of life in 98 (70%), harmful use of alcohol in 23 (16.4%) and suicidal ideation in 11 (7.8%) patients. Young age, recent onset, higher PASI and facial involvement show significant association with depression, anxiety and poor quality of life. ConclusionScreening for psychological morbidity should be performed in patients with severe psoriasis especially younger patients with recent onset disease. Higher DLQI points to concomitant psychological morbidity and it should be performed in all the patients.

Prevalence of psychological morbidities and their influential variables among nurses in a designated COVID-19 tertiary care hospital in India: A cross-sectional study

Background and Aim: Nurses are the main part of the health work force, performing their duties as frontline warriors against the novel coronavirus pandemic. Nurses involved in the care of infected (COVID-19) patients, may feel more discomfort physically, and experience greater psychological morbidities. The main aim of the study is to evaluate the prevalence of anxiety and stress among nurses in a designated COVID-19 hospital and variables that influence these psychological problems. Materials and Methods: Nurses working in the designated tertiary care hospital were invited to participate in an online cross-sectional survey (dated, 5–15 September 2020). A total sample size of 236 was calculated. A self-administered questionnaire regarding sociodemographic characteristics, COVID-19-related experiences, perceived threat regarding COVID-19 and two scales (Generalised Anxiety Disorder-7 and Perceived Stress Scale-10) for assessment of anxiety, and stress was applied to nurses. Chi-square test and multiple regression analysis were used to investigate the predictors (risk and protective) of psychological morbidities in nurses. Results: On analysis of 209 participants, it was revealed that 65 (31.1%) participants have anxiety symptoms and 35.40% have moderate-to-high level of stress. Being proud of working in this profession was the only protective factor from such psychological morbidities. The identified risk factors for greater anxiety symptoms and moderate-to-high level stress were working experience of more than 10 years (odds ratio [OR] = 3.36), direct involvement in care of suspected/diagnosed patients (OR = 3.4), feeling worried about being quarantined/isolated (OR = 1.69), and high risk of being infected at job (OR = 2.3 for anxiety and OR = 2.1 for moderate-to-high stress). Conclusions: Deteriorating psychic health of nurses is one of the major outcomes during COVID-19 pandemic in India which warrants the necessity of providing psychological support to all the nurses particularly those who are frontline workers and have working experience of more than 10 years and controlling the risk factors related to these problems.

Prevalence of psychological morbidities among general population, healthcare workers and COVID-19 patients amidst the COVID-19 pandemic: A systematic review and meta-analysis

This review was done to synthesize the existing evidence on the prevalence of various psychological morbidities among general public, healthcare workers and COVID-19 patients amidst this pandemic situation. Systematic searches were conducted in various databases and search engines such as Medline, Chinese national knowledge infrastructure, Cochrane library, ScienceDirect, and Google Scholar from inception until 22 April 2020. Newcastle Ottawa scale was used to assess the quality of included studies. We carried out a meta-analysis with random-effects model and reported pooled prevalence with 95% confidence intervals (CIs).A total of 50 studies were included in the review. Only seven studies (14%) had low risk of bias. Pooled prevalence rate of psychological morbidities includes poor sleep quality (40%), stress (34%), psychological distress (34%), insomnia (30%), post-traumatic stress symptoms (27%), anxiety (26%), depression (26%). Pooled prevalence rate of psychological morbidities with respect to impact of event due to COVID-19 pandemic was 44% (95%CI-42% to 47%). The burden of these psychological morbidities was highest among the COVID-19 patients followed by healthcare workers and general population.

Prevalence of cognitive dysfunction, psychological morbidity and abuse in the community-based elderly population in India

BackgroundThe elderly population in India is expected to grow enormously by 2050 owing to an increase in life expectancy. Community-based data on the prevalence of psychological morbidity, abuse and cognitive...

Prevalence of psychological morbidities among patients with chronic obstructive pulmonary disease

Prevalence of psychological morbidities among patients with chronic obstructive pulmonary disease

Prevalence of psychological morbidities and their influential variables among nurses in a designated COVID-19 tertiary care hospital in India: A cross-sectional study.

Background:Nurses are the main part of the health workforce, performing their duties as frontline warriors against the novel coronavirus pandemic. Nurses involved in the care of infected (COVID-19) patients, may feel more discomfort physically and experience greater psychological morbidities.Aims and Objectives:The main aim of the study is to evaluate the prevalence of anxiety and stress among nurses in a designated COVID-19 hospital and variables that influence these psychological problems.Methodology:Nurses working in the designated tertiary care hospital were invited to participate in an online cross-sectional survey (dated, September 5–15, 2020). A self-administered questionnaire regarding sociodemographic characteristics, COVID-19-related experiences, perceived threat regarding COVID-19, and two scales (Generalized Anxiety Disorder-7 and Perceived Stress Scale-10) for the assessment of anxiety and stress was applied to nurses. Chi-square test and multiple regression analysis were used to investigate the predictors (risk and protective) of psychological morbidities in nurses.Results:On analysis of 209 participants, it was revealed that 65 (31.1%) participants have anxiety symptoms and 35.40% have moderate to the high level of stress. Being proud of working in this profession was the only protective factor from such psychological morbidities. The identified risk factors for greater anxiety symptoms and moderate-to-high-level stress were, working experience of >10 years (odds ratio [OR] = 3.36), direct involvement in the care of suspected/diagnosed patients (OR = 3.4), feeling worried about being quarantined/isolated (OR = 1.69,) and high risk of being infected at the job (OR = 2.3 for anxiety and OR = 2.1 for moderate-to-high stress).Conclusions:Deteriorating the psychic health of nurses is one of the major outcomes during the COVID-19 pandemic in India which warrants the necessity of providing psychological support to nurses and controlling the risk factors related to these problems. Greater focus should be on the frontline and experienced nurses.

Psychological morbidity in Nepali cross-border migrants in India: a community based cross-sectional study

BackgroundSince Nepali cross-border migrants can freely enter, work and stay in India, they are largely undocumented. The majority is involved in semi-skilled or unskilled jobs with limited labour rights and social security, a fact which predisposes them to psychological distress. We aimed to assess the prevalence of and factors associated with psychological morbidity among Nepali migrants upon their return from India.MethodsA community based cross-sectional study was conducted in six districts of Nepal between September 2017 and February 2018. A total of 751 participants who had worked at least six months in India and returned to Nepal were interviewed from 24 randomly selected clusters. The General Health Questionnaire (GHQ)-12 was used to measure the psychological morbidity. Data were analysed using Poisson regression analysis.ResultsThe majority was younger than 35 years (64.1%), male (96.7%), married (81.8%), had at least a primary education (66.6%), and belonged to Dalit, Janajati and religious minorities (53.7%). The prevalence of psychological morbidity was 13.5% (CI: 11.2–16.1%). Participants aged 45 years and above (adjusted prevalence ratio (aPR) = 2.74), from the Terai (aPR = 3.29), a religious minority (aPR = 3.64), who received no sick leave (aPR = 2.4), with existing health problems (aPR = 2.0) and having difficulty in accessing health care (aPR = 1.88) were more likely than others to exhibit a psychological morbidity.ConclusionThis study demonstrated that psychological morbidity was prevalent in the study participants and varied significantly with individual characteristics, work conditions and health. Multifaceted approaches including psychological counselling for returnees and protection of labour and health rights in the workplace are recommended to help reduce psychological morbidity.

Prevalence of Psychological Problems Among Adolescent Students of Selected Private School at Itahari Sub-Metropolis of Eastern Nepal

Background: Adolescence is the second decade of life, the crucial period demanding significant adjustment in physical, psychological and social dimensions. The main aim of this study was to access the psychological problems of adolescents in Itahari sub-metropolis.&#x0D; Methods: A cross-sectional study design and consecutive sampling technique was adopted for the study. The study was conducted in selected schools of Itahari Metropolitan city. From the selected schools, students of class 7 to 12 with the age range of 11-19 years were included in the study. Sample size was calculated considering the prevalence of Psychosocial Problem of similar setting. The instrument for data collection was self-administered pediatric checklist for youth, an internationally valid tool, which was divided in three parts. Part I related to socio-demographic information, part II consisted of questions regarding family and school related factors and part III was the standard tool to measure psychosocial problem.&#x0D; Results: The prevalence of psychological morbidity on the basis of total difficulties score was found to be 23.9% (11) in male whereas 31.5% (17) was abnormal in female. Among males, 76.1% (35) was found to have normal scores as compared to 68.5% (37) in females although the difference was found to have no statistical significance.&#x0D; Conclusions: The adolescent age groups have to face various psychological problems and are likely to be very common. School mental health and social services have the potential to affect the prevalence of these and other psychological disorders by assisting in the assessment, referrals and management of the affected students.

The Prevalence of Psychological Morbidities and the Determinant of care givers of children with intellectual disabilities, in specialized centers in Jeddah 2018

Introduction: Intellectual disabilities are sever chronic issue that distressing the affected people and their caregivers, This study aim to assess the burden and the psychological disease of the caregivers of the intellectual disabilities patients and to find out whether there is any relation between the perceived burden and the independent variable such as age, sex, education, economic status and the type of intellectual disabilities in specialized centres in Jeddah city. Materials and Methods: Through a cross sectional design a convenient sampling method was used to select the study subjects who were attending the selected centres in Jeddah during the period from 1,July to 30 sept,2018. using systemic sampling technique, a 201 caregivers were included in the study (130 Cerebral Palsy and 71 Autism), The (Zarit burden interview) and the(general health questioner 28) were used to assess the burden and the psychological disease of the caregivers. Main Results: The study showed that burden and general health score were significantly correlated with the risk factors of age, marital status, number of children and monthly income of the caregivers of cerebral palsy patients, while there is no significant difference between participants of the care givers of the Autism patients. The mean of subjective and objective burden of the caregivers for the two intellectual disabilities was mild to moderate, while regarding the general health score the caregivers not suffering from any of the main domain psychological disease (anxiety/insomnia, somatic symptom, severe depression or social dysfunction). Conclusion: Taking care of intellectual disabilities patients can be a burden to the caregivers as well as they suffer from negative life influence, which calls for more study in the future to increase the supports for caregivers. Keywords: Caregivers, Intellectual disabilities, Burden, Psychological disease, Autism, Cerebral palsy, Saudi Arabia

The English National Cohort Study of Flooding and Health: the change in the prevalence of psychological morbidity at year two

BackgroundThe longer term impact of flooding on health is poorly understood. In 2015, following widespread flooding in the UK during winter 2013/14, Public Health England launched the English National Study of Flooding and Health. The study identified a higher prevalence of probable psychological morbidity one year after exposure to flooding. We now report findings after two years.MethodsIn year two (2016), a self-assessment questionnaire including flooding-related exposures and validated instruments to screen for probable anxiety, depression and post-traumatic stress disorder (PTSD) was sent to all participants who consented to further follow-up. Participants exposure status was categorised according to responses in year one; we assessed for exposure to new episodes of flooding and continuing flood-related problems in respondents homes. We calculated the prevalence and odds ratio for each outcome by exposure group relative to unaffected participants, adjusting for confounders. We used the McNemar test to assess change in outcomes between year one and year two.ResultsIn year two, 1064 (70%) people responded. The prevalence of probable psychological morbidity remained elevated amongst flooded participants [n = 339] (depression 10.6%, anxiety 13.6%, PTSD 24.5%) and disrupted participants [n = 512] (depression 4.1%, anxiety 6.4%, PTSD 8.9%), although these rates were reduced compared to year one. A greater reduction in anxiety 7.6% (95% confidence interval [CI] 4.6–9.9) was seen than depression 3.8% (95% CI 1.5–6.1) and PTSD: 6.6% (95% CI 3.9–9.2). Exposure to flooding was associated with a higher odds of anxiety (adjusted odds ratio [aOR] 5.2 95%, 95% CI 1.7–16.3) and depression (aOR 8.7, 95% CI 1.9–39.8) but not PTSD. Exposure to disruption caused by flooding was not significantly associated with probable psychological morbidity. Persistent damage in the home as a consequence of the original flooding event was reported by 119 participants (14%). The odds of probable psychological morbidity amongst flooded participants who reported persistent damage, compared with those who were unaffected, were significantly higher than the same comparison amongst flooded participants who did not report persistent damage.ConclusionsThis study shows a continuance of probable psychological morbidity at least two years following exposure to flooding. Commissioners and providers of health and social care services should be aware that the increased need in populations may be prolonged. Efforts to resolve persistent damage to homes may reduce the risk of probable psychological morbidity.

Psychological morbidity and substance use among patients with hypertension: a hospital-based cross-sectional survey from South West Ethiopia

BackgroundPsychological morbidity and substance use disorders have been linked to cardiovascular diseases; affecting patients’ medical outcome and quality of life. However, little is known about psychological morbidity and substance use among patients with hypertension in Ethiopia. Therefore, we aimed to assess psychological comorbidity and substance use among hypertensive patients in Southwest Ethiopia.MethodsA cross-sectional study was conducted among 396 hypertensive patients on follow-up at Jimma University Teaching Hospital in Ethiopia during the study period. Structured questionnaires were used to assess alcohol use, khat chewing and cigarette smoking. Psychological morbidity was assessed using the Kessler-6 scale. Multiple logistic regression analysis was carried out to identify the independent association between outcome and explanatory variables.ResultsThe prevalence of psychological morbidity among hypertensive patients was 31.6%. Of the total participants, 31 (7.8%) of them had alcohol use disorders and 79 (19.9%) of them were using khat regularly at the time of the study. Singles were more likely to have psychological morbidity than married participants (AOR = 4.72; 95% CI 1.83, 12.20, p = 0.001), whereas those who were able to ‘read and write’ were less likely to have psychological morbidity than non-literate ones (AOR = 0.46; 95% CI 0.24, 0.89, p = 0.02). However, no association was seen between psychological morbidity and substance use (khat chewing, alcohol use and cigarette smoking), belief about hypertension, ever discontinuation of medication and lifestyle (exercise, salt consumption).ConclusionPsychological morbidity and substance use are prevalent among hypertensive patients on follow-up at the hospital. The findings of the study imply that there is a need for further studies to understand the effect of psychological morbidity on the clinical outcomes of hypertensive patients.

Prevalence of Psychological Morbidity among Medically Ill Patients

Prevalence of Psychological Morbidity among Medically Ill Patients

Abstract P5-15-04: Prognostic understanding and associations with mood and quality of life in patients with metastatic breast cancer

Abstract Background: Data suggest that patients with metastatic cancer who understand their prognosis are more likely to prefer and receive care concordant with their wishes. Despite the importance of prognostic information for patients’ decision-making, there are no current data describing prognostic understanding in patients with metastatic breast cancer (MBC). The aims of this study were to describe prognostic understanding in patients with MBC and to explore its associations with mood, distress, and quality of life (QOL). Methods: We conducted a cross-sectional study of 50 patients who were receiving first- or second-line chemotherapy for MBC. Participants completed a series of questionnaires. We used a 13-item questionnaire to assess patients’ perceptions of their prognosis and goal of therapy. We evaluated mood, level of distress, and QOL using the Hospital Anxiety and Depression Scale (HADS), the Distress Thermometer (DT), and the Functional Assessment of Cancer Therapy-Breast (FACT-B), respectively. Results: The majority of patients (92%) reported it was at least somewhat important to know details about their prognosis. 19/47 (40%) patients reported that the primary goal of treatment was to cure their cancer, and 21/46 (46%) patients reported that the chance of cure was at least somewhat likely (≥25% chance of cure). 24/49 (49%) patients viewed themselves as terminally ill. There was a high prevalence of psychological morbidity in our patient cohort. 24/48 (50%) patients screened positive for distress (distress thermometer ≥4), 17/50 (34%) patients reported significant anxiety symptoms (HADS-Anxiety ≥ 8), and 11/50 (22%) patients reported significant depression symptoms (HADS-Depression ≥ 8). Distress, depression, and anxiety were each associated with lower QOL scores (93.0 vs. 114.0, p&amp;lt;0.001; 87.9 vs. 107.8, p=0.002; and 85.5 vs. 112.8, p&amp;lt;0.001, respectively). Patients who acknowledged their illness as terminal reported higher depression than those who did not perceive themselves as terminally ill (M=6.1 vs. 2.5, p=0.0006). Conclusion: Although the majority of patients with MBC receiving first- or second-line chemotherapy feel it is important to know detailed information about their prognosis, many incorrectly perceive that their cancer is curable. Accurate prognostic understanding was associated with increased depression symptoms. This study highlights the need to develop interventions to enhance patients’ prognostic understanding while providing adequate psychosocial support. Citation Format: Amanda Parkes, Jennifer A Shin, Helen Knight, Stephen M Schleicher, Areej El-Jawahri, Lara Traeger, Jennifer S Temel. Prognostic understanding and associations with mood and quality of life in patients with metastatic breast cancer [abstract]. In: Proceedings of the Thirty-Seventh Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2014 Dec 9-13; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2015;75(9 Suppl):Abstract nr P5-15-04.