Prevalence Of Percutaneous Coronary Intervention Research Articles

Charlson comorbidity index in predicting deaths in COVID-19 patients

Aim. To assess the clinical performance and factors associated with inhospital mortality in patients with coronavirus disease 2019 (COVID-19).Material and methods. Our results are based on data from hospital charts of inpatients hospitalized in the Asinovskaya District Hospital in the period from March 11, 2020 to December 31, 2020, with a verified COVID-19 by polymerase chain reaction. The study included 151 patients, the median age of which was 66,2 (50- 92) years (women, 91; 60,3%). The study endpoints were following hospitalization outcomes: discharge or death. Depending on the outcomes, the patients were divided into 2 groups: the 1st group included 138 patients (survivors), while the 2nd one included 13 patients (death). To objectify the severity of multimorbidity status, the Charlson comorbidity index was used. The final value was estimated taking into account the patient age by summing the points assigned to a certain nosological entity using a calculator table.Results. Hypertension was recorded in the majority of patients — 79,5%, chronic kidney disease — in 61,1%. The prevalence of type 2 diabetes and coronary artery disease was high — 31,8% each. Prior myocardial infarction was diagnosed in 11,3% of cases. The prevalence of percutaneous coronary intervention and coronary bypass surgery was 5,3% and 3,3%, respectively. Stroke was detected in 9,3% of participants. Prior chronic pulmonary pathologies in COVID-19 patients were rare (asthma — 3,3%, chronic obstructive pulmonary disease — 2,0%). In order to predict the death risk in COVID-19 patients, a logistic regression analysis was performed, which showed that age and Charlson comorbidity index were the most significant predictors.Conclusion. Independent factors of inhospital mortality were age and Charlson’s comorbidity index. The risk assessment model will allow clinicians to identify patients with a poor prognosis at an earlier disease stage, thereby reducing mortality by implementing more effective COVID-19 treatment strategies in conditions with limited medical resources.

Demographics, practice patterns and long-term outcomes of patients with non–ST-segment elevation acute coronary syndrome in the past two decades: the CREDO-Kyoto Cohort-2 and Cohort-3

ObjectivesTo evaluate patient characteristics and long-term outcomes in patients with non–ST-segment elevation acute coronary syndrome (NSTEACS) in the past two decades.DesignMulticenter retrospective study.SettingThe Coronary REvascularization Demonstrating Outcome Study in Kyoto...

Impact of percutaneous coronary intervention on short and long-term prognosis of elderly patients with acute myocardial infarction from 2010 to 2017 in Japanese population

Abstract Background Advances in therapies have successfully decreased short-term mortality in patients with acute myocardial infarction (AMI). Although aging population is recently increasing in developed countries, there are few reports about the association between prevalence of percutaneous coronary intervention (PCI) and long-term prognosis in elderly patients with AMI in Japan. Purpose The aim of this study was to clarify the prevalence of PCI and the impact of PCI on short and long-term prognosis of elderly patients with AMI. Methods and results We investigated the prevalence of PCI and short-term mortality in 4,109 patients with AMI who were registered in Yamagata AMI Registry from 2010 to 2017. Long-term mortality was investigated using data from death certification in July 2019. We divided patients with AMI into three age groups (group 1, <65 years old; group 2, 65–79 years old; and group 3, ≥80 years old). Short-term mortality within 30 days was 6.5%, 12.1%, and 28.6%, respectively. Also, prevalence of PCI was 88.0%, 84.7%, and 62.7%, respectively. Multivariate analysis revealed that age, PCI, and severity of Killip classification were significantly associated with short-term mortality after adjustment for confound factors in group 3. Since the prevalence of PCI in group 3 was the lowest among three groups, the cause of PCI not being executed was investigated in 1,429 patients aged ≥80 years old. Elderly patients who didn't undergo PCI was older, more women, and had higher prevalence of chronic kidney disease, previous stroke, and severe Killip classification. Multivariate analysis revealed that age and Killip III/IV were significantly associated with non-executed PCI after adjustment for confound factors. Next, we investigated impact of PCI on long-term mortality in elderly patients who escaped acute death. Multivariate Cox hazard analysis revealed that PCI was associated with lower mortality after adjustment for confound factors (adjusted hazard ratio 2.47, 95% CI: 1.47–4.06; p=0.0008). Conclusion Lower prevalence of PCI and higher short-term mortality were observed in elderly patients with AMI aged ≥80 years old. PCI ameliorated long-term mortality as well as short-term mortality in elderly patients with AMI. Funding Acknowledgement Type of funding source: None

Myocardial damage associated with elective percutaneous coronary intervention in Chinese patients: a retrospective study.

ObjectiveTo determine the prevalence of percutaneous coronary intervention (PCI) related myocardial damage (injury or myocardial infarction), investigate several cardiac biomarkers, explore possible risk factors and assess survival in patients undergoing elective PCI.MethodsPatients >18 years of age who had undergone an elective PCI at Huashan hospital in Shanghai, China from October 2016 to June 2017 and had baseline and post-PCI results available for four cardiac biomarkers (cTnT, CK-MB mass, hs-CRP and NT-ProBNP) were eligible. Patients were separated into two groups according to whether or not they had PCI related myocardial damage.ResultsOf the 143 patients who were eligible for the study, 75 (52%) were classified as ‘controls,’ and 68 (48%) had PCI related myocardial damage. Of the 68 patients, 64 (45%) had PCI related myocardial injury and 4 (3%) had PCI related myocardial infarction. Elderly Chinese patients, with high systolic blood pressure on admission and who required multiple coronary segments for PCI had a high risk of myocardial damage. Relative cTnT or relative CK-MB mass may be useful cardiac biomarkers for monitoring PCI related myocardial damage, especially at 24h post-PCI. There was no significant difference in survival rates between controls and those with myocardial complications.ConclusionsPCI related myocardial damage is common but appears to have no impact on prognosis. Senior age, high systolic blood pressure and multiple coronary segments for PCI are risk factors.

A comparative characteristics of patients with acute coronary syndrome according to data of Ukrainian and European registers 2009-2015.

The aim of this work was to compare basic anamnestic and demographic data in Ukrainian and European groups included in the register SNAPSHOT 2009 and local group ofthe year2015. It wasestablished that by the year2015 patients’ age advanced (from 65±13 to 68.6±11.2 years), as well as part of women (from 30% to 47.5%), previous myocardial infarction frequency (from 22% to 34.7%), heart failure (from 10% to 42.6%), and chronic kidney disease (from 2% to 14.9%). The increase of prevalence of arterial hypertension (88.1%) in local group was founded. The average body mass index had tendency to increasing (28.6±4.4 kg/m2); the part of patients with increased body mass index was equal among men and women. Simultaneous increase of such comorbidities as arterial hypertension, chronic kidney disease and complications of previous myocardial infarction and heart failure in the local register with a lower prevalence of such risk factors as smoking (13.9%), dyslipidemia (10.9%), and frequency of diabetes (10.9%) were founded. The prevalence of peripheral atherosclerosis was lower in the year 2015 research group than in European one (1% vs 6%). The prevalence of percutaneous coronary intervention (3.1%) and CABG (1.1%) for diagnostic and treatment of ischemic heart disease was extremely low in 2015 year group. The prevalence of previous stroke and chronic obstructive pulmonary disease remained approximately the samein all registers groups. The tendency of increase of malignancy prevalence in anamnesis was founded (5.9%), and probably it was associated with increase of average patients’ age.

Percutaneous Coronary Intervention in Nonagenarians: Prevalence, Indications, Vascular Approach and Mortality at 3 months

Background: Percutaneous coronary intervention (PCI) in nonagenarians has been shown to be feasible, with a high success rate. However, there is paucity of data regarding the prevalence, vascular access, procedural data and mortality after PCI in this population. Methods: All patients aged 90 and older referred to our institution from 2004 to 2014 for coronary angiogram were included in our retrospective study. Clinical and procedural data including vascular access and 3-month mortality rates were obtained for all patients. Results: A total of 26696 PCI were performed over the last 11 years, of which 177 PCI (0.66%) were realized in 167 nonagenarians. The prevalence of PCI in nonagenarians increased from 0.17% in 2004 to 1.22% in 2014. In this population, with an age of 92 ± 2 years and 51.4% of males, 76 (43%) PCI were performed in the setting of ST-elevation myocardial infarction, and 89 (50%) of the procedures were non-ST elevation myocardial infarction or unstable angina. Transradial approach (TRA) was used in 76 (43%) and transfemoral approach (TFA) in 101 (57%) procedures. Comparing TRA to TFA, the total fluoroscopic time and contrast volume was similar between the two groups. Overall complications, including cardiogenic shock, iatrogenic coronary dissection, perforation or no reflow phenomenon occurred in 22 of 177 procedures (12.4%). Overall survival rate was 92.8% at 3 months. Conclusion: The majority of the procedures was performed in acute coronary syndrome clinical setting. TRA and TFA were comparable in terms of fluoroscopic time and contrast volume. Overall procedural success rate was high and complication rates were low.

PCV34 - The Effectiveness of Statins in the Treatment of Cardiovascular Disease: Cross-Sectional Study with Paired Groups from Electronic Patient Records

Electronic Patient Record has proven useful to assess the benefits, harms and costs in the real world. To describe the association between the use of statins and cardiovascular events in patients with myocardial ischemia by means an Electronic Patient Record (ePR) as the basis for a retrospective cohort study. To evaluate the association between the use of statins and cardiovascular events, we conducted a cross-sectional study with patients in the ePR of the Heart Institute (InCor) - University of São Paulo Medical School. Patients were considered for the period between 2004 and 2012 and evaluated in terms of the association between the use of statins with prevalence of percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG) and inpatient mortality. A total of 46,757 patients were randomly selected and matched for gender, age group (18-49/50-59/60-69/>70), and category of cardiovascular disease diagnosis, being from three ICD-10 groupings, I20-I25/I63-I69/G45/I70. The pairing resulted in two groups, each of them with 14,654 patients, a group with prescription of statin (SG) and a group for comparison (CG) without statin. A total of 67.4% of the patients registered in the ePR used statins. The presence of reverse causality, very common in cross-sectional studies, was observed in patients submitted to revascularization procedures. Revascularization was made present in 14% of CG versus 42% of SG, which is justified by the drug administration for care of patients undergoing those procedures. Mortality was 5.8% in CG and 4.7% in SG, with prevalence rates of 80%. The absolute reduction in the prevalence of death between groups was 1.1% (95%CI:0,6-1,6%) in favor of the use of statins. Statins were not prescribed to approximately one third of the patients, the use of statins was higher in patients undergoing revascularization procedures and, was also associated with a 20% reduction in the occurrence of mortality.

Prevalence of percutaneous coronary intervention is a key to reduce a higher early mortality in female patients with acute myocardial infarction: the Yamagata AMI registry

Prevalence of percutaneous coronary intervention is a key to reduce a higher early mortality in female patients with acute myocardial infarction: the Yamagata AMI registry

The prevalence of percutaneous coronary intervention in Beijing residents with coronary heart disease, 2007–2009

ObjectivesTo describe the prevalence of percutaneous coronary intervention (PCI) in Beijing residents with coronary heart disease (CHD) from 2007 to 2009.MethodThe study is based on a subset of records extracted...