Prevalence Of Electronic Cigarette Use Research Articles

Trends in Current Electronic Cigarette Use Among Youths by Age, Sex, and Race and Ethnicity

This cross-sectional study examines prevalence of electronic cigarette use among youths by age, sex, and race and ethnicity from 2013 to 2022.

Disparities in Electronic Cigarette Use: A Narrative Review.

The prevalence of electronic cigarette use has been declared an epidemic by the U.S. Surgeon General in 2018, particularly among youth aged 18-24 years old. Little is known about the differential use of e-cigarettes by different groups. PubMed, Cochrane, and Google Scholar were used to find relevant articles. A total of 77 articles were included. The extant literature reveals disparities in e-cigarette use by race/ethnicity and sexuality/gender. There are conflicting conclusions regarding disparities by socioeconomic status.

Use of Electronic Cigarettes among Secondary School Students and their Association with Depressive Symptoms: Findings from a National Secondary School Survey in Thailand

Objective: to describe: 1) the prevalence of electronic cigarette use among Thai secondary school students, stratified by grade levels and sex; 2) the extent that depressive symptoms were associated with former and current use of electronic cigarette.Material and Methods: We conducted a cross-sectional study from secondary school students in Thailand in years 7, 9, and 11 of the 12-years educational system. We randomly sampled 113 schools in 21 provinces and Bangkok, randomly sampled classrooms in the school, and invited all students present in the sampled classrooms to participate in the study. All data were collected using self-administered questionnaires. We measured depressive symptoms using the Patient Health Questionnaire-2 (PHQ-2) instrument, and measured electronic cigarette use with adapted versions of existing instruments. Data analyses included descriptive statistics and logistic regression analyses with adjustment for sampling weights.Results: A total of 23,659 students responded and provided adequately completed questionnaires. Approximately 12.3% of the participants reported a lifetime history of using electronic cigarette. Electronic cigarette use was more common among males and older students. There seemed to be a threshold in the association between the level of depressive symptoms and ever vs. never use of electronic cigarette, and the association was strongest at a PHQ-2 score of 6 vs. 0 (adjusted odd ratio (OR)=1.72; 95% confidence interval (CI)=0.98, 3.03). A similar association was found between current vs. former or never use of electronic cigarette and having a PHQ-2 score of 6 vs. 0 (adjusted OR=1.84; 95% CI=0.96, 3.52).Conclusion: We found associations between depressive symptoms and electronic cigarette use. However, limitations with regard to the lack of temporality, measurement issues, and lack of generalizability should be considered as caveats in the interpretation of the study findings.

Online Interest for Electronic Cigarettes Using Google Trends in the UK: A Correlation Analysis

Background: Google Trends provides an easily accessible and cost-effective method of providing real-time insight into user interest. Objective: to address the gap in UK prevalence data for e-cigarettes by analyzing Google Trends to identify correlations with official data from Action on Smoking and Health. The study further evaluates Google Trend’s sensitivity to real-time events and the ability for predictive models to forecast future data based on Google Trends. Methods: UK Google Trends data from 2012 to 2021 was analyzed to assess (a) the most popular electronic nicotine device terminology; (b) statistically significant points in time; (c) correlations between Relative Search Volumes and official reports on electronic cigarette use and (d) whether Google Trends could predict future patterns in data. These were achieved using Locally Weighted Scatterplot Smoothing regression, Pruned Exact Linear Time Method, cross correlation, and Autoregressive Integrated Moving Average algorithms respectively. Results: “Vape” was revealed to be the most popular electronic nicotine device terminology with a correlation coefficient greater than +0.9 when compared to official electronic cigarette consumption data within a one-year timescale (lag 0). Results from ARIMA modeling were varied with the algorithms forecasted trends line occasionally lying outside of a 95% prediction interval. Conclusion: Google Trends may correspond to population-based prevalence of electronic cigarette use. The changing trends coincide with changing policy decisions. Google Trends based prediction for online interest in electronic cigarettes requires further validation so should currently be used in conjunction with other traditional methods of data collections.

The Prevalence of Electronic Cigarette Use Among College Students of Taibah University and Symptoms of Cardiovascular Disease.

Electronic cigarettes (e-cigarettes) have been increasing in popularity among young adults due to the misconception about the safety of e-cigarettes. Our study aims to identify the prevalence rate of e-cigarette use among college students, the reason behind their use, and the relationship between the use of electronic cigarettes and cardiovascular symptoms among college students. An online questionnaire was sent to students of Taibah University between 2021 and 2022. Data from this survey were analyzed to obtain the prevalence of e-cigarette use among Taibah University students and to compare the demographic and health characteristics differences between e-cigarette users and non-users. The prevalence of cardiovascular symptoms was also compared between the two groups. A total of 519 students participated in this study. The prevalence rate of e-cigarette use was 24%. Compared to non-users, e-cigarette users were more likely to be male (71% vs. 40%, p < 0.01), overweight (44% vs. 32%, p = 0.01), and drug users (4% vs. 1%, p = 0.01). E-cigarette users were likelier to complain of cardiovascular symptoms, including chest pain (19% vs. 10%, p = 0.01), shortness of breath (14% vs. 7%, p = 0.02), and palpitation (12% vs. 6%, p = 0.03). The association between e-cigarette use and cardiovascular symptoms was significant even after adjusting for students' characteristics. Students' main reasons for e-cigarette use were to enjoy the flavors of e-cigarettes, quit tobacco smoking, and improve depression. The prevalence rate of e-cigarette use among college students was 24%. The self-reported cardiovascular disease symptoms rate was doubled among e-cigarette users compared to non-users.

A cross-sectional study of the prevalence of electronic cigarette use, knowledge and attitudes among Saudi youth

A cross-sectional study of the prevalence of electronic cigarette use, knowledge and attitudes among Saudi youth

Prevalence of electronic cigarette use and its determinants in us persons of Hispanic/Latino background: The Hispanic community health study / study of Latinos (HCHS/SOL)

ObjectiveTo determine the prevalence and determinants of electronic nicotine delivery systems (ENDS) use among Hispanic/Latino adults from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). MethodsCross-sectional data collected between the years 2015–2017 were analyzed to assess ENDS use (ever (current: use ≤ past 30 days; former: use > past 30 days) and never) among 11,623 adults (mean age 47 years±0.3 years; 52% women). Weighted prevalence estimates were reported, and age-adjusted logistic regression models were used to examine associations between sociodemographic and clinical exposures with ENDS use. ResultsThe prevalence of current and former ENDS use was 2.0% and 10.4%, respectively. Having ever used ENDS was associated with prevalent coronary artery disease. Current ENDS use was higher in males and associated with higher education, English language preference, and Puerto Rican background compared with nonsmokers and cigarette-only smokers (all p<0.05). ConclusionsHispanic/Latino individuals who are young adults, male, US-born, and have high acculturation were more likely to report current ENDS use. These findings could inform preventive and regulatory interventions targeted to Hispanics/Latinos.

Prevalence of Electronic Cigarette Use and its Determinants in Us Persons of Hispanic/Latino Background: The Hispanic Community Health Study / Study of Latinos (Hchs/Sol)

Prevalence of Electronic Cigarette Use and its Determinants in Us Persons of Hispanic/Latino Background: The Hispanic Community Health Study / Study of Latinos (Hchs/Sol)

Switching from cigarettes to electronic nicotine delivery system: rapid systematic review and meta-analysis and economic aspects.

To assess how and in what extent the electronic nicotine delivery systems (ENDS) use substituted the consumption of traditional combustible cigarettes (c-cigarettes, c-cig). We performed a systematic review of the literature up to August 2019 in scientific databases. Primary outcomes were proportion of complete or partial substitution of conventional to electronic cigarettes and related economic aspects. Secondary outcomes were odds ratio of substitution and country-wise time trends. We retrieved 3,628 references and included 49 studies, providing economic and epidemiological data. Economic studies of cross-price elasticity showed that combustible cigarettes are partially substitutable for electronic cigarettes. Most studies reported that electronic cigarettes consumption prevalence increased over time. Three studies reported a significant reduction of combustible cigarettes consumed per day among dual users (combustible- plus electronic- cigarettes users) versus combustible-cigarettes users. The pooled adjusted odds ratio of quitting combustible cigarettes among electronic cigarettes users versus never or past electronic cigarettes (e-cigarettes, e-cig) users was 1.19 (95% confidence interval 1.09 to 1.30; heterogeneity score 0%). Longitudinal studies showed globally a growing prevalence of electronic cigarettes use, mainly in adolescents. A negative relationship between consumption and price increase of electronic and combustible cigarettes was found. The chance of quitting smoking combustible cigarettes among current electronic nicotine delivery systems users was increased with respect to never- or past- electronic nicotine delivery systems users. Economic studies reported that electronic cigarette is partially substitutable for combustible cigarettes.

Abstract 10690: Prevalence of Electronic Cigarette Use and Its Determinants in Us Persons of Hispanic Heritage: The Hispanic Community Health Study / Study of Latinos (HCHS/SOL)

Introduction: Popularity and use of electronic nicotine delivery systems (ENDS or e-cigarettes), have increased tremendously in the United States (US). Yet, data in a representative sample of US Hispanics/Latinos is limited. We determined the prevalence and correlates of ENDS use from the national Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Methods: Cross-sectional data collected between the years 2015–2017 were analyzed to assess ENDS use (ever (current: use ≤ past 30 days; former: use &gt; past 30 days) and never) among 11,623 adults aged 23+ years. Weighted prevalence estimates were reported and age-adjusted logistic regression models were used to examine associations between sociodemographic, lifestyle/behavioral, and clinical exposures with ENDS use (vs. nonsmokers and cigarette-only smokers, separately). Results: Mean age 47 years ± 0.3 and 52% women. The weighted prevalence of current and former ENDS use was 2.0% and 10.4%, respectively. Over 67% of current ENDS users reported dual-cigarette use. Current ENDS use prevalence estimates ranged from 1.1% in Hispanics/Latinos of South American background to 2.1% in Hispanics/Latinos of Mexican and Puerto Rican background. In logistic regression models, compared with nonsmokers, increased odds of current ENDS use was associated with males (OR=4.90, p&lt;0.001), higher education (OR=2.03, p&lt;0.05), English language preference (OR=7.59, p&lt;0.001), Puerto Rican background (OR=2.09, p&lt;0.05), a high level of physical activity (OR=4.02, p&lt;0.001), and history of alcohol use (OR=15.93, p&lt;0.001). Older age (≥45 years) (OR=0.30, p&lt;0.001), foreign-born participants (OR=0.12, p&lt;0.001), and those with obesity (OR=0.60, p&lt;0.05) and type 2 diabetes (OR=0.46, p&lt;0.001) had lower odds of current ENDS use. These trends were generally similar when cigarette-only smokers were the reference group. Having ever used ENDS was associated with prevalent coronary artery disease. Conclusions: Our study suggest that Hispanic/Latino individuals who are young adults, male, US-born, or have high acculturation are more likely to report current ENDS use.

Predictors of Greater Vaping Dependence and Higher Vaping Frequencies among Canadian Youth and Young Adults over 12-Month

Background: The prevalence of electronic cigarette use has doubled among Canadian youth and young adults in recent years. However, little is known about the predictors of greater vaping nicotine dependence. This study identifies variables associated with greater Penn-State Electronic Cigarette Dependence Index (PS-ECDI) scores and higher vaping sessions per month (SPM) among this population.&#x0D; Methods: Data were drawn from a longitudinal study that recruited 1048 Canadian participants aged 16-26 in 2018. Quota sampling was used to ensure enough regular e-cigarette users were recruited. The current study restricted analyses to the 459 participants who were baseline vapers and have completed both the baseline and 12-month follow-up surveys. Linear regression analyses were employed, with the use of the best subset modelling strategy to obtain reduced models.&#x0D; Results: Baseline vapers who were ≥ 18 and married or cohabiting, had used other tobacco products, had 30 or more puffs per vaping session, started vaping at an earlier age, vaped to quit/reduce smoking, and had used a disposable cigarette-like vaping device and/or an advanced box or tubular device and/or a pod vape in the last 6-month were associated with greater PS-ECDI scores compared to their respective counterparts. Additionally, baseline vapers who were ≥18 and married or cohabiting, had used cannabis, had 30 or more puffs per vaping session; vaped to reduce/quit smoking and/or because friends vape; had used a pod vape in the last 6-month were more likely to have higher SPM at the 12-month follow-up compared to their respective counterparts.&#x0D; Conclusion: 11% of the participants were classified as high vaping nicotine dependence and 42% of the participants had increased their SPM over 1 year. The findings provide targets for vaping reduce or cessation programs and potential policy change in the regulation and sales of pod vape.

Electronic Cigarette Use and Cigarette-Smoking Cessation Attempts Among Stroke Survivors in the US

This cross-sectional study estimates the prevalence of electronic cigarette use among actively smoking stroke survivors in the US and evaluates its association with at least 1 cigarette-smoking cessation attempt in the past year.

Stressful life events and electronic cigarette use during pregnancy.

Smoking during pregnancy poses a significant health risk for infant well-being. Prior research has linked experiencing stressful life events (SLEs) during pregnancy to prenatal smoking. However, extant research has not assessed whether SLEs experienced during pregnancy are a risk factor for prenatal electronic cigarette use. This study investigates the association between SLEs and electronic cigarette use during the third trimester of pregnancy. We employ data on 70,626 recent mothers from the 2016-2018 Pregnancy Risk Assessment Monitoring System. Logistic and multinomial logistic regression models were used to examine the association between SLEs and electronic cigarette use during the third-trimester of pregnancy. The prevalence of electronic cigarette use increased alongside an accumulating history of SLEs (0 SLEs=0.4%; 1-2 SLEs=0.9%; 3-5 SLEs=1.9%; 6+ SLEs=5.0%). Logistic regression models found 6 or more SLEs were associated with 4.7 times higher odds of electronic cigarette use relative to 0 SLEs after adjusting for demographic and socioeconomic characteristics (AOR=4.705, 95% CI=2.960, 7.479). Study findings also showed that women who experienced greater levels of SLEs had a higher prevalence of using any nicotine products (i.e., exclusive electronic cigarette user, exclusive cigarette user, dual user), relative to being a non-smoker. Findings from multinomial logistic regression models revealed that a higher number of SLEs was associated with an increased relative risk of all smoking outcomes. Still, these associations were particularly pronounced in the case of exclusive electronic cigarette user (ARR=8.485, 95% CI=4.900, 14.692) and dual-use (ARR=8.348, 95% CI=4.113, 16.945) when participants experienced 6 or more SLEs (relative to 0 SLEs). Considering the potentially harmful ramifications of electronic cigarette use during pregnancy there is a need for interventions that reduce stressful experiences and decrease smoking during pregnancy.

Prevalence of Electronic Cigarette Use Among Adult Workers — United States, 2017–2018

Prevalence of Electronic Cigarette Use Among Adult Workers — United States, 2017–2018

Prevalence and risk factors of e-cigarette use among working-age adults with and without disabilities in 2017–2018

BackgroundDespite rapid growth in the use of electronic cigarettes (ECIGs) in the U.S., few studies have examined the national prevalence of ECIG use among adults with disabilities. ObjectiveTo assess the national prevalence of and risk factors for ECIG use among working-age (18–64 years) adults with and without disabilities. MethodsThis observational study relied on a sample of 560,858 working-age adults from the 2017–2018 Behavioral Risk Factor and Surveillance System (BRFSS). We conducted descriptive analyses to estimate the prevalence of ECIG use and multivariate logistic regression models to examine factors associated with ECIG use among adults with and without disabilities. ResultsECIG use was more prevalent among adults with a cognitive disability (12.0%), an independent living disability (11.0%), or two or more disabilities (9.2%), compared to adults without disabilities (4.8%). In the multivariate analysis, adults with a cognitive disability (OR = 1.45; p < .001), ambulatory disability (OR = 1.23; p < .05), and those with two or more disabilities (OR = 1.49; p < .001) had an increased likelihood of ECIG use compared to those without disabilities. Current smokers had greater odds of using ECIGs compared to never smokers (OR = 8.53, p < .001). ConclusionsAdults with cognitive disabilities and independent living disabilities had more than twice the prevalence of ECIG use compared to adults without disabilities. Future studies should monitor the rising prevalence and risk factors for ECIG use as well as examine longitudinal associations between using ECIGs, dual use with cigarette smoking, and health outcomes among adults with disabilities.

Increasing Prevalence of Electronic Cigarette Use among Medical Students. Repeated Cross-Sectional Multicenter Surveys in Germany and Hungary, 2016–2018

Background Use of electronic cigarettes (e-cigarettes) is gaining popularity among young adults. Medical students' nicotine use behavior is of particular interest because of their impending role in health promotion. Objectives: Aim of our study is to assess changes that occurred between 2016 and 2018 in the prevalence of e-cigarette use among medical students and to explore associations between e-cigarette use, demographic characteristics, and cigarette smoking. Self-administered questionnaire surveys were used to obtain cross-sectional data of medical students in Budapest and Pécs, Hungary, and Dresden, Germany. Results: Sample sizes for 2016 and 2018 were 2297 and 1514, respectively. In the whole sample, past-30-day use of e-cigarettes increased from 4.5% to 8.0% (p < 0.001). The increase in e-cigarette use was significant in both genders (from 3.6% to 5.6% among females, p = 0.028, and from 5.9 to 11.4% among males, p < 0.001). Prevalence of e-cigarette use was higher among Hungarian students than among German students (2.2% versus 5.7% in 2016, and 4.1% versus 10.5% in 2018, p < 0.05 for both years). There was no significant difference in e-cigarette use among different academic years. The ratio of e-cigarette users increased significantly among current cigarette smokers but not among nonsmokers. We could not detect a decrease in cigarette smoking. Conclusions: Prevalence of e-cigarette use increased significantly among medical students without a reduction in cigarette smoking. Medical schools should add the topic of e-cigarettes to their curricula and need to develop cessation programs to help their students quit both cigarettes and e-cigarettes.

Prevalence of Electronic Cigarette Use and its Determinants among 13-to-15-Year-Old Students in Greece: Results from the 2013 Global Youth Tobacco Survey (GYTS).

Electronic cigarette use has increased over the past decade. Its potential role in smoking cessation, in addiction and as a ‘gateway’ to tobacco smoking is subject to intense research. This cross-sectional study, carried out in 2013, aims to present the habits of students aged 13–15 in Greece with regard to e-cigarettes and investigate potential risk factors and the relationship between e-cigarettes, tobacco smoking and other nicotine products. It is the first such study to be carried out in Greece. The survey was based on the standardized methodology of the Global Youth Tobacco Survey. All potential associations were investigated using multiple logistic regression. In total 2.8% of the 4096 participating students were current e-cigarette users and 12.3% of them were ever users. E-cigarette use was associated with male gender, being older, current use of combustible tobacco products and e-cigarette use in the family. Ever e-cigarette use, being older, female gender and higher pocket money were associated with an increased susceptibility to tobacco smoking. E-cigarette prevalence in Greece in 2013 was similar to that of other, developed countries. The smoking and vaping habits of adolescents must be monitored in order to assess trends over time and whether any policy alterations are necessary.

Prevalence of Electronic Cigarette Use Among Adolescents in New Jersey and Association With Social Factors

Use of electronic cigarettes (e-cigarettes) is high among adolescents, but the extent to which the JUUL e-cigarette brand accounts for the high prevalence has not been explored using population-based surveys. To examine e-cigarette and JUUL use among adolescents in New Jersey. Survey study using data from the 2018 New Jersey Youth Tobacco Survey, a cross-sectional statewide representative survey of tobacco use. The survey was school based and sampled New Jersey students in grades 9 to 12. Use of tobacco products; JUUL as first tobacco product tried; exposure to JUUL at school; number of friends perceived as JUUL users; liking or following a tobacco brand on social media; and buying or receiving tobacco-branded merchandise. Prevalence ratio (PR) for current and frequent e-cigarette use, inclusive of JUUL. In this sample of 4183 adolescents, respondents were 49.6% female and 49.6% non-Hispanic white. Students were evenly distributed across grades 9 through 12. Overall, the estimate for current use of e-cigarettes inclusive of JUUL was higher (24.2%; 95% CI, 22.5%-25.9%) compared with current use assessed by use of e-cigarettes only (17.8%; 95% CI, 16.4%-19.4%) or JUUL use only (21.3%; 95% CI, 19.7%-23.0%). Divergence in e-cigarette use estimates was higher for certain subgroups, including female respondents and non-Hispanic black respondents. Also, 88.8% (95% CI, 86.6%-91.1%) of current e-cigarette users reported JUUL as a brand they used. Hispanic students (PR, 0.78; 95% CI, 0.69-0.89) and non-Hispanic students of other races (PR, 0.64; 95% CI, 0.51-0.81) were significantly less likely than non-Hispanic white students to be current e-cigarette users, and students in 12th grade were more likely than those in 9th grade to be current users (PR, 1.29; 95% CI, 1.11-1.48). Current e-cigarette use was positively associated with current use of other tobacco products (PR, 2.57; 95% CI, 2.24-2.95), endorsing a tobacco brand on social media (PR, 1.43; 95% CI, 1.19-1.72), having tobacco-branded merchandise (PR, 1.70; 95% CI, 1.46-1.97), having close friends who used JUUL (PR, 3.81; 95% CI, 3.17-4.58), and seeing JUUL used on school grounds (PR, 1.43; 95% CI, 1.24-1.65). Estimates of prevalence were greater when modeling frequent use. This study found that prevalence of current and frequent e-cigarette use among adolescents was higher when inclusive of JUUL use, and JUUL was by far the most common e-cigarette brand used, providing support for inclusion of brand-specific questions when assessing e-cigarette use. The results also identify characteristics of adolescents who may be more likely to use e-cigarettes.

Association of prevalence of electronic cigarette use with smoking cessation and cigarette consumption in England: a time-series analysis between 2006 and 2017.

AimsTo provide up‐to‐date estimates of how changes in the prevalence of electronic cigarette (e‐cigarette) use in England have been associated with changes in smoking cessation activities and daily cigarette consumption among smokers in England.DesignTime–series analysis of population trends.SettingEngland.ParticipantsParticipants came from the Smoking Toolkit Study, which involves repeated, cross‐sectional household surveys of individuals aged 16 years and older in England. Data were aggregated on approximately 1200 past‐year smokers each quarter (total n = 50 498) between 2007 and 2017.MeasurementsPrevalence of e‐cigarette use in current smokers was used to predict (a) prevalence of quit attempts among last‐year smokers, (b) overall quit rates among last‐year smokers and (c) mean cigarette consumption per day among current smokers. Prevalence of e‐cigarette use during a quit attempt among last‐year smokers was used to predict (a) quit success rate among last‐year smokers and (b) overall quit rates among last‐year smokers.FindingsOverall quit rates increased by 0.054% [95% confidence interval (CI) = 0.032–0.076, P < 0.001] and 0.050% (95% CI = 0.031–0.069, P < 0.001) respectively for every 1% increase in the prevalence of e‐cigarette use by smokers and e‐cigarette use during a quit attempt. Quit success rates increased by 0.060% (95% CI = 0.043–0.078, P < 0.001) for every 1% increase in the prevalence of e‐cigarette use during a quit attempt. No clear evidence was found for an association between e‐cigarette use and either prevalence of quit attempt (BAdj = 0.011, 95% CI = −0.046 to 0.069, P = 0.698) or cigarette consumption (BAdj = 0.019, 95% CI = −0.043 to 0.082, P = 0.542).ConclusionChanges in prevalence of e‐cigarette use in England have been positively associated with the overall quit rates and quit success rates but not clearly associated with the prevalence of quit attempts and mean cigarette consumption.

Differential patterns of alcohol and nicotine intake: Combined alcohol and nicotine binge consumption behaviors in mice.

Late adolescence and young adulthood, corresponding to the high school and college years, are vulnerable periods for increased alcohol and nicotine use. The dramatic increase in the prevalence of electronic cigarette use is particularly concerning in these age groups. Late adolescents and young adults are more likely to engage in cycles of binge drug consumption, and alcohol and nicotine are frequently used together. However, there are few data examining the combination of alcohol and nicotine in binge models in animal models. In this study, our objectives were to determine how voluntary nicotine consumption beginning in late adolescence influenced subsequent binge alcohol consumption in young adulthood, how a combination of alcohol and nicotine binge consumption differed from alcohol-only binge consumption, and whether nicotine would be consumed when presented in a binge procedure. Male C57BL/6J mice voluntarily consumed unsweetened alcohol and nicotine in continuous-access bottle-choice procedures in combination with cycles of drinking-in-the-dark. Our results show that experience with voluntary nicotine consumption in late adolescence did not affect subsequent binge alcohol consumption in early adulthood. However, mice that consumed nicotine in adolescence showed an initial decrease in alcohol preference, and consequently increase in nicotine preference, on the first session of combined ethanol and nicotine binge consumption in adulthood compared with mice that drank only water during late adolescence. Lastly, we found that mice readily consumed unsweetened nicotine when presented in a binge procedure, and the level of consumption exceeded the nicotine consumption observed in the combination alcohol and nicotine binge. Our data show that expansion of the patterns of alcohol and nicotine co-consumption in a mouse models is possible, which will enable us to dissect relevant molecular targets underlying these consumption patterns and better inform drug development efforts.