Prevalence Of Alcohol Consumption Research Articles

Abstract PO3-09-11: Age Group Analysis of Breast Cancer Patterns in Brazil: Findings from Population-Based Registries

Abstract Background: The rising breast cancer (BC) incidence among young women is potentially influenced by modifiable genetic and reproductive risk factors, as well as the increased incidence among older women may be associated with lifestyle-related factors and screening programs. This study examines BC incidence and mortality rates across different age groups in Brazil, focusing on clinicopathological and sociodemographic variations. Patients and methods: By using data from 13 Brazilian Population-Based Cancer Registries spanning the period 2010-2015, this study analyzed incidence trends among women with BC. Crude incidence ratios (CIRs) and the annual average percent change (AAPC) were computed. Additionally, clinical and sociodemographic information from 348 Hospital-Based Cancer Registries covering 2000-2019 was incorporated. Mortality data for the years 2000-2020 were obtained from the National Mortality Information System. Comparative analyses were conducted across three predefined age groups: < 40, 40-69, and ≥ 70 years. Statistical significance was defined as a p-value < 0.05, while a threshold of more than 5% difference in proportional values was used as a criterion to identify clinically relevant differentials. Results: Between 2010 and 2015, a total of 205,966 newly diagnosed cases of BC were documented. The CIRs were 7.1/100,000 for the age group < 40, 156.5/100,000 for the age group 40-69, and 247.5/100,000 for the age group ≥ 70 years. Within the scope of the analyzed age groups, it was observed that solely the age group < 40 years exhibited a noteworthy and persistent increase in the rate of occurrence (AAPC +1.6; 95% CI: 1.0 to 2.2; p < 0.001). This age group also displayed a significantly higher proportion of black women (53%, p < 0.001), a higher prevalence of alcohol consumption (20.5%, p < 0.001), and a greater likelihood of receiving multiple treatment modalities (60.7%, p < 0.001). In contrast, the age group ≥ 70 years experienced a more extended time delay of > 60 days from diagnosis to treatment onset (54%, p < 0.001), while exhibiting a higher utilization rate of hormone therapy (45.3%, p < 0.01). The mortality rates witnessed a significant increase across all age categories, with the age group < 40 years manifesting the most substantial escalation (AAPC +1.8%; 95% CI: 1.6 to 2.1; p < 0.001). This rise was comparatively more than double the rate observed in the 40-69 age group (AAPC +0.7%; 95% CI: 0.5 to 0.8; p < 0.001) and exactly twice as high as the rate recorded in the age group > 70 years (AAPC +0.9%; 95% CI: 0.7 to 1.1 ; p < 0.001). Conclusion: This study reveals substantial disparities in BC incidence and mortality rates, as well as significant differences in clinicopathological and sociodemographic features, among women aged < 40 compared to those in the 40-69 and ≥ 70 years in Brazil. Keywords: Breast cancer; age groups; incidence; mortality. Citation Format: Jesse Lopes da Silva, Andreia Cristina De Melo, Lucas Zanetti de Albuquerque, Mariana Espirito Santo Rodrigues, Luiz Claudio Santos Thuler. Age Group Analysis of Breast Cancer Patterns in Brazil: Findings from Population-Based Registries [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO3-09-11.

Real-world evidence from a retrospective study on suicide during depression: clinical characteristics, treatment patterns and disease burden

BackgroundSuicide stands as both a primary symptom and the direst outcome of major depressive disorder (MDD). The scarcity of effective treatment strategies makes managing MDD patients with suicide especially challenging. Hence, it is crucial to investigate disease characteristics and efficacious therapeutic strategies for these patients, drawing insights from disease databases and real-world data.MethodsIn this retrospective study, MDD patients hospitalized between January 2013 and December 2020 were investigated using Electronic Health Records (EHR) data from Beijing Anding Hospital. The study enrolled 4138 MDD patients with suicidal ideation or behavior (MDS) and 3848 without (MDNS). Demographic data, clinical attributes, treatment approaches, disease burden, and re-hospitalization within one year of discharge were extracted and compared.ResultsPatients in the MDS group were predominantly younger and female, exhibiting a higher prevalence of alcohol consumption, experiencing frequent life stress events, and having an earlier onset age. Re-hospitalizations within six months post-discharge in the MDS group were significantly higher than in the MDNS group (11.36% vs. 8.91%, p < 0.001). Moreover, a more considerable fraction of MDS patients underwent combined electroconvulsive therapy treatment (56.72% vs. 43.71%, p < 0.001). Approximately 38% of patients in both groups were prescribed two or more therapeutic regimes, and over 90% used antidepressants, either alone or combined. Selective serotonin reuptake inhibitors (SSRIs) were the predominant choice in both groups. Furthermore, antidepressants were often prescribed with antipsychotics or mood stabilizers. When medication alterations were necessary, the favoured options involved combination with antipsychotics or transitioning to alternative antidepressants. Yet, in the MDS group, following these initial modifications, the addition of mood stabilizers tended to be the more prioritized alternative.ConclusionsMDD patients with suicidal ideation or behaviour displayed distinctive demographic and clinical features. They exhibited intricate treatment patterns, a pronounced burden of illness, and an increased likelihood of relapse.

Hepatitis-C-Related Hepatocellular Carcinoma, Still a Relevant Etiology beyond a Hepatitis C Infection Cure.

In the past decades, global changes, including hepatitis B vaccination, hepatitis B and C antiviral therapies, and the increasing prevalence of steatotic liver disease, have influenced the landscape of liver cancer etiologies. We performed a retrospective study focused on the etiological factors of de novo hepatocellular carcinoma (HCC) diagnoses in an academic center between 2019 and 2022. Among 352 consecutive patients with HCC, alcohol-related liver disease was the predominant etiology (33.3%), followed by hepatitis C (HCV) infection (30.7%). Significant associations were found between HCC etiology and patient demographics, BCLC stage at diagnosis, and cirrhosis prevalence. Whereas accessibility to antiviral therapy is granted, HCV infection remains as one of the main HCC etiologies. MASLD-related HCC, although growing globally, is not as relevant in our area. Strong public policies need to be implemented to prevent alcohol consumption, the main etiology of liver disease and liver cancer.

Prevalence of Alcohol Consumption in Mozambique: Analysis Based on Household Budget Survey (IOF 2022)

Worldwide the excessive consumption of alcohol in 2016 was considered as responsible for 5% of deaths and more than 200 illnesses and injuries. There are several studies conducted around the world to understand the prevalence of alcohol consumption. However, in Mozambique, there are few studies conducted to determine the prevalence of alcohol consumption, as well as, to characterize the consumers, using data from nationally representative surveys. The current study, identify the prevalence of alcohol consumption in Mozambique, according to socio-demographic characteristics of population using data from the Household Budget Survey (IOF 2022) carried out by the National Statistics Institute in 2022. The analysis of data was based in descriptive statistics. The study results revel that the prevalence of alcohol consumption in Mozambique is 24.6%, higher among men (27%), compared to woman (23%). The prevalence is high among people between 18 - 65 years old (26%) and people with higher education (34%). Around 17% of teenagers, between 15 and 17 years old, in both sexes, purchased and consumed alcoholic beverages, despite the prohibition of Mozambican legislation. The provinces of Tete (37.2%), Maputo (32.3%) and Zambézia (30.3%) have the highest prevalence of alcoholic beverages consumption and the province of Niassa (3.7%) has the lowest prevalence. Beer (46%) is the most consumed alcoholic beverage in Mozambique, followed by traditional alcoholic beverages (44%).

The prevalence of alcohol consumption and its related factors in adolescents: Findings from Global School-based Student Health Survey.

Alcohol consumption has become very common among adolescents in recent years and its prevalence varies in different countries. This study aimed to investigate the prevalence of alcohol consumption and related factors in adolescents aged 11 to 16 years. This descriptive cross-sectional study was performed on 288385 adolescents (girls, 53.9% of total) aged 11 to 16 years. In the present study, the GSHS data (2003-2018) available to public on the websites of the US Centers for Disease Control and Prevention (CDC) and WHO was used. To investigate the factors affecting alcohol consumption, univariate and multivariate logistics models with 95% confidence limits were used. The overall prevalence of alcohol consumption in adolescents was 25.2%, which was 28.3% and 22.4% in boys and girls, respectively. Among the surveyed countries, the highest prevalence was in Seychelles (57.9%) and the lowest in Tajikistan (0.7). Multivariate analysis showed that the Age for 16 and more than 16 years old (OR = 3.08,95%CI: 2.54-3.74), truancy for more than 10 days (OR = 1.24, 95%CI: 1.08-1.43), loneliness at sometimes of the times (OR = 1.04, 95%CI: 1.01-1.07), insomnia at most of the times (OR = 1.85, 95%CI: 1.70-2.01), daily activity (OR = 1.03, 95%CI: 1.00-1.07), bullied for 1-9 Days in a month (OR = 1.24, 95%CI: 1.09-1.40), cigarette (OR = 4.01, 95%CI: 3.86-4.17), used marijuana for more than 10 days in a month (OR = 5.58, 95%CI: 4.59-7.78), had sex (OR = 2.76, 95%CI: 2.68-2.84), and suicide plan (OR = 1.48, 95%CI: 1.42-1.54) were important factors affecting drinking alcohol. (Table 4). In this study, the sensitivity, specificity, positive predictive value, and negative predictive value were 42.79%, 93.96%, 70.80%, and 82.75. According to the results of the present study, the prevalence of alcohol consumption among teenagers was high. Therefore, it is suggested that demographic, family, and psychological factors should be taken into consideration in health programs for the prevention and treatment of alcohol consumption in adolescents.

Reducing Alcohol Use to Prevent Cancer Deaths: Estimated Effects Among U.S. Adults

The Dietary Guidelines for Americans, 2020-2025 recommends non-drinking or no more than 2 drinks for men or 1 drink for women in a day. However, even at lower levels, alcohol use increases the risk for certain cancers. This study estimated mean annual alcohol-attributable cancer deaths and the number of cancer deaths that could potentially be prevented if all U.S. adults who drank in excess of the Dietary Guidelines had instead consumed alcohol to correspond with typical consumption of those who drink within the recommended limits. Among U.S. residents aged ≥20 years, mean annual alcohol-attributable cancer deaths during 2020-2021 that could have been prevented with hypothetical reductions in alcohol use were estimated. Mean daily alcohol consumption prevalence estimates from the 2020-2021 Behavioral Risk Factor Surveillance System, adjusted to per capita alcohol sales to address underreporting of drinking, were applied to relative risks to calculate population-attributable fractions for cancers that can occur from drinking alcohol. Analyses were conducted during February-April 2023. In the U.S., an estimated 20,216 cancer deaths were alcohol-attributable/year during 2020-2021 (men: 14,562 [72.0%]; women: 5,654 [28.0%]). Approximately 16,800 deaths (83% of alcohol-attributable cancer deaths, 2.8% of all cancer deaths) could have been prevented/year if adults who drank alcohol in excess of the Dietary Guidelines had instead reduced their consumption to ≤2 drinks/day for men or ≤1 drink/day for women. Approximately 650 additional deaths could have been prevented annually if men consumed 1 drink/day, instead of 2. Implementing evidence-based alcohol policies (e.g., increasing alcohol taxes, regulating alcohol outlet density) to decrease drinking could reduce alcohol-attributable cancers, complementing clinical interventions.

Alcohol consumption and work-related health problems: Exploring the perceptions of Nigerian informal automobile artisans

Alcohol consumption is one of the leading factors that lead to work-related health problems worldwide. However, alcohol consumption among informal workers in developing countries is unknown. Using a qualitative method; this study explores the perception of the informal automobile artisans in Nigeria about alcohol consumption and its contribution to workplace health problems among the working population. Data were collected through in-depth interviews with a purposive sample of 43 automobile artisans from Osun State. Thematic analysis was done using MAXQDA 2020 software. The artisans identified a range of injuries and illnesses. They described the severity of these work-related health problems (WHPs) as either minor, serious or very serious. Moreover, the study shows the prevalence of alcohol consumption among the group. The artisans noted that alcohol consumption is one of the major causes of accidents and injuries among members. They further explained that members take alcohol to get strength for their tasks. The study concluded that using the workplace as a platform to address alcohol consumption is critical to promoting a healthy and productive work environment.

Prevalence of alcohol problems in Russia in periods of socio-economic crises

The article investigates changes in the alcoholic behavior of the Russian population for more than 40 years. The study focuses on the relationship between socio-economic crises and the prevalence of alcohol problems. It is shown that in periods of social and economic crises two behavioral patterns can manifest themselves: increased alcohol consumption due to increased psychological distress and decreased consumption due to budgetary constraints. Analysis of statistical data and survey materials allows us to conclude that Russia is characterized by large and repeated fluctuations in the prevalence of alcohol consumption. On the basis of quantitative data we trace the dynamics of citizens’ well-being and alcohol consumption from 1994 to 2022. We consider such parameters as the level of life satisfaction, the level of anxiety about the impossibility to provide oneself with the most necessary things in the next 12 months, as well as self-assessment of the economic situation and the feeling of one’s own powerlessness. It has been revealed that it is not so much the difficult economic situation that contributes to the tense alcohol situation in Russia as the process of abrupt transformations: changes in the socio-economic situation, both for the better and for the worse, can increase the level of alcoholization.

Using the Socio-ecological Model to Explain the Findings of Prevalence and Demographic Correlates of Alcoholic Beverage Consumption among Adolescents in Public Schools in Uganda

INTRODUCTION: Consumption of alcohol among the youth could be attributable to socio-demographic characteristics. This paper anchors on the socio-ecological model to expound on the prevalence and socio-demographic correlates of alcohol consumption among adolescents in public secondary schools. Specifically, the model was used to explore gender, religious affiliation, form or class of study, social media use, friendships, and involvement in places of entertainment as possible predictors of alcohol consumption. METHOD: Within the framework of the socio – ecological model, we employed a cross-sectional survey with quantitative methods to explore socio - ecological covariates of alcohol consumption among the youth in public secondary schools. The sample comprised 1819 participants, yielding a 91.8% response rate. Males were relatively more numerous (59.3%), and the mean age was 17.3 (SD = 1.9). Bivariate and multivariate logistic regressions were employed to deduce the association of selected demographics with the consumption of beer, wine, and spirits. RESULTS: The prevalence of alcohol consumption was generally high. Multivariate logistic regression showed a significant gender difference in the consumption of beer and spirits. Females had lower odds of consuming beer and spirits. Students in the Muslim and Pentecostal dominions were less likely to consume beer, wine, and spirits than their Roman Catholic and Anglican counterparts. Students in the Roman Catholic dominion had higher odds of consuming any type of alcohol compared to other religions. Loving to be in places of entertainment and the use of social media significantly predicted the consumption of beer, wine, and spirits. CONCLUSION: These results could bear importance in demanding benchmarking of ecologically specific advocacy against alcohol consumption in schools. Further, results imply that youth drinking regulatory frameworks may be inclusive of the alcohol industry including not only the producers of alcohol but also a large network of distributors, wholesalers, bars, and advertisers. Interventions for in-school youth drinking may need to be developed by benchmarking with and involving institutions at different levels of the ecological model, such as religious institutions, healthcare services, media, and the village councils.

Anxiety and Depressive Symptoms Associated to Alcohol Consumption in Health Care Workers

Abstract. – Alcohol consumption in healthcare personnel is of great importance due to the impact it causes on the individual's well-being and quality of life, even generating behavioral problems such as anxiety and depressive symptoms. These situations can lead to the consumption of alcohol to cope with situations that may arise in the workplace. The objectives of the study include describing the characteristics of health personnel, identifying the prevalence of alcohol consumption by sex and age, as well as determining the relationship between anxiety, depressive symptoms and alcohol consumption in health personnel. Methods: Descriptive, predictive correlational study that included 420 participants. Sociodemographic information was collected, as well as data on anxiety through the GAD-7, depressive symptoms measured with the PHQ9 and alcohol consumption through the AUDIT, in compliance with the ethical aspects of the General Health Law on Health Research. Results: Seventy percent were women, significant difference was identified in the prevalence of last month (χ2= 5.393, p= 0.020) and last seven days (χ2= 4.328, p= 0.037) by sex. The age group between 18 and 33 years indicated higher consumption in all four prevalences. Positive and significant relationship was shown in anxiety and depressive symptoms ( = .644, p&lt; 0.001), anxiety and alcohol consumption ( = 0.216, p&lt; 0.001), depressive symptoms and alcohol consumption ( = 0.210, p&lt;0.001). A significant negative relationship was identified for age and anxiety ( = -0.218, p&lt; 0.001), age and depressive symptoms ( = -.261, p&lt; .001), as well as age and alcohol consumption ( = -0.228, p&lt; 0.001). Conclusion: The present study provides information on the impact of mental disorder on health personnel through associations between anxiety, depressive symptoms and alcohol consumption.

Global Trends in the Prevalence of Alcohol Consumption Among School-Going Adolescents Aged 12–15 Years

PurposeAdolescent alcohol consumption is detrimental to multiple facets of health. However, there is a scarcity of data available on time trends in adolescents' alcohol consumption particularly from non-Western countries and low- and middle-income countries. Thus, we examined the temporal trend of alcohol use in a large representative sample of school-going adolescents aged 12–15 years from 22 countries in Africa, Asia, and the Americas. MethodsData from the Global School-based Student Health Survey were analyzed. Alcohol consumption referred to consuming alcohol on at least one day in the past 30 days. Crude linear trends of past 30-day alcohol consumption by country were assessed by linear regression models. ResultsData on 135,426 adolescents aged 12–15 years were analyzed [mean (standard deviation) age 13.8 (1.0) years; 52.0% females]. The overall mean prevalence of past 30-day alcohol consumption was 14.1%. Of the 22 countries included in the study, increasing, decreasing, and stable trends were observed in 3, 8, and 11 countries, respectively. Specifically, significant increases were observed in Benin between 2009 (16.1%) and 2016 (38.6%), Myanmar between 2007 (0.9%) and 2016 (3.6%), and Vanuatu between 2011 (7.6%) and 2016 (12.2%). The most drastic decrease was observed in Samoa between 2011 (34.5%) and 2017 (9.8%), but the rate of decrease was modest in most countries. DiscussionAmong school-going adolescents, decreasing trends in alcohol consumption were more common than increasing trends, but the rate of decrease was limited in most countries, suggesting that more global action is required to curb adolescent alcohol consumption.

A mobile phone intervention to reduce heavy drinking: a preliminary analysis of anchoring heuristics

BackgroundPreliminary evidence has been presented for interventions focused on preventing alcohol consumption or reducing the occurrence of episodes of excessive drinking. The anchoring text message intervention is a newly proposed theory-based approach to reducing heavy drinking among youth. The current study tests the preliminary efficacy of this intervention for reducing heavy drinking among Mexican youth.MethodsFocusing on a sample of sixteen Mexican youths—nine not-heavy drinkers and seven heavy drinkers—the participants completed a survey on alcohol consumption and anchoring heuristics. Pretest and post-test questionnaire data were collected to evaluate the effectiveness of the intervention. The anchoring text messages consisted of strategies to limit alcohol use and feedback reminder messages. Assessments were conducted at baseline, four weeks of intervention, and post-intervention.ResultsLogistic regression analyses indicated a significant effect on heavy drinking episodes post-intervention. The post-intervention anchoring effects among the heavy drinker participants were different from those among the non-heavy drinkers in terms of reporting heavy drinking and future drinking. The anchoring heuristic-based intervention reduced the quantity of drinking and the future estimation of drinking and improved the ability to reject alcohol in the heavy drinker group.ConclusionsThese findings provide preliminary support for the effectiveness of the anchoring heuristic-based intervention, conducted through text messages sent by mobile phone to reduce alcohol consumption. The intervention promoted a reduction in alcohol consumption. Future research should be directed toward investigating the anchoring effects among heavy drinkers.

Using the Socio-ecological Model to Explain the Findings of Prevalence and Demographic Correlates of Alcoholic Beverage Consumption among Adolescents in Public Schools in Uganda

INTRODUCTION: Consumption of alcohol among the youth could be attributable to socio-demographic characteristics. This paper anchors on the socio-ecological model to expound on the prevalence and socio-demographic correlates of alcohol consumption among adolescents in public secondary schools. Specifically, the model was used to explore gender, religious affiliation, form or class of study, social media use, friendships, and involvement in places of entertainment as possible predictors of alcohol consumption. METHOD: We employed a cross-sectional survey with quantitative methods. The sample comprised 1819 participants, yielding a 91.8% response rate. Males were relatively more numerous (59.3%), and the mean age was 17.3 (SD = 1.9). Bivariate and multivariate logistic regressions were employed to deduce the association of selected demographics with the consumption of beer, wine, and spirits. RESULTS: The prevalence of alcohol consumption was generally high. Multivariate logistic regression showed a significant gender difference in the consumption of beer and spirits. Females had lower odds of consuming beer and spirits. Students in the Muslim and Pentecostal dominions were less likely to consume beer, wine, and spirits than their Roman Catholic and Anglican counterparts. Students in the Roman Catholic dominion had higher odds of consuming any type of alcohol compared to other religions. Loving to be in places of entertainment and the use of social media significantly predicted the consumption of beer, wine, and spirits. CONCLUSION: At the multivariate level, some socio-ecological factors could account for differential alcohol consumption among the students. Individual student-level factors such as gender and the institutional factor of religion could explain alcohol consumption among the students. Specifically, gender and religion were significantly associated with alcohol consumption. It is recommended that ecological differences and “gendered models” are considered as part of the interventions for in-school youth drinking.

Abstract B129: The association of Covid-19 pandemic restrictions with patient-reported outcomes and lifestyle behaviors among breast cancer survivors: Evidence from a cohort of Black and Hispanic breast cancer survivors in New Jersey

Abstract Purpose: The onset of COVID-19 pandemic restrictions in the US since March 2020 has worsened the disproportionate burden of physical and mental health challenges faced by vulnerable Black and Hispanic breast cancer (BrCa) patients. BrCa survivors experienced delays in their cancer treatments and limited access to supportive care, which may lead to further physical, and psychosocial challenges during an already difficult time. This study aimed to evaluate the association of the COVID-19 pandemic restrictions with patient-reported outcomes (PROs) (i.e. health-related quality of life (HRQoL), sleep, perceived stress, coping and financial toxicity), and lifestyle behaviors (i.e. obesity, smoking, and alcohol) among Black and Hispanic BrCa survivors participating in the Women’s Circle of Health Follow-Up 1 (WCHSFU1) and the New Jersey Breast Cancer Survivors Study (NJBCS), two ongoing population-based studies in New Jersey. Methods: The NJBCS followed similar methods to those in the WCHSFU1. We included a total of 447 Black (npre=364 and npost=83) and 182 Hispanic (npre=102 and npost=80) BrCa survivors who completed a home interview ~24 months post-diagnosis, from 2017 to 2023. The COVID-19 pandemic era was defined as pre- (recruited prior to March 2020) and post-(recruited after March 2020) pandemic. To assess the association of the pandemic with PROs and lifestyle behaviors we employed multivariable adjusted Poisson regression models with robust standard errors to estimate prevalence ratios with 95%CI. Results: Compared to the pre-pandemic group, Black survivors in the post-pandemic group were more likely to be educated, to have higher income, and to be foreign-born, while Hispanic women were significantly more likely to have private insurance and higher HRQoL, physical and emotional well-being mean scores (p&amp;lt;0.05 for all). Adjusted Poisson models indicated that Hispanic women in the post-pandemic group had 1.53 times higher prevalence of low resilience (vs high resilience) (PR:1.53 95% CI: 1.15-2.04), compared to the pre-pandemic group. Whereas Black women in the post-pandemic group reported a higher prevalence of clinically significant sleep disturbance and efficiency (PR: 1.43 95% CI: 1.23-1.68 and PR:1.50 95% CI: 1.30 – 1.73, respectively), compared to the pre-pandemic group. Both Hispanic and Black women in the post-pandemic group showed significantly less perceived stress and a lower prevalence of alcohol consumption. Conclusion: We found heterogeneity in the prevalence of PROs and lifestyle behaviors by pandemic era among Black and Hispanic survivors. Notably, we also noticed differences in demographic characteristics of women participating after the onset of the pandemic, which highlights the importance of considering the impact of the pandemic in all aspects of research, including the interpretation of findings. Continuing research to untangle important factors contributing to racial and ethnic differences in patient characteristics, PROs and lifestyle behaviors post-pandemic in cancer survivorship is warranted. Citation Format: Carola T. Sanchez-Diaz, Nur Zeinomar, Hari S. Iyer, Marley Perlstein, Chi-Chen Hong, Bo Qin, Elisa V. Bandera. The association of Covid-19 pandemic restrictions with patient-reported outcomes and lifestyle behaviors among breast cancer survivors: Evidence from a cohort of Black and Hispanic breast cancer survivors in New Jersey [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr B129.

Using the Socio-ecological Model to Examine Prevalence and Demographic Correlates of Alcoholic Beverage Consumption among Adolescents in Public Schools in Uganda

INTRODUCTION: Consumption of alcohol among the youth could be attributable to socio-demographic characteristics. This paper anchors on the socio-ecological model to expound on the prevalence and socio-demographic correlates of alcohol consumption among adolescents in public secondary schools. Specifically, the model was used to explore gender, religious affiliation, form or class of study, social media use, friendships, and involvement in places of entertainment as possible predictors of alcohol consumption. METHOD: We employed a cross-sectional survey with quantitative methods. The sample comprised 1819 participants, yielding a 91.8% response rate. Males were relatively more numerous (59.3%), and the mean age was 17.3 (SD = 1.9). Bivariate and multivariate logistic regressions were employed to deduce the association of selected demographics with the consumption of beer, wine, and spirits. RESULTS: The prevalence of alcohol consumption was generally high. Multivariate logistic regression showed a significant gender difference in the consumption of beer and spirits. Females had lower odds of consuming beer and spirits. Students in the Muslim and Pentecostal dominions were less likely to consume beer, wine, and spirits than their Roman Catholic and Anglican counterparts. Students in the Roman Catholic dominion had higher odds of consuming any type of alcohol compared to other religions. Loving to be in places of entertainment and the use of social media significantly predicted the consumption of beer, wine, and spirits. CONCLUSION: At the multivariate level, some socio-ecological factors could account for differential alcohol consumption among the students. Individual student-level factors such as gender and the institutional factor of religion could explain alcohol consumption among the students. Specifically, gender and religion were significantly associated with alcohol consumption. It is recommended that ecological differences and “gendered models” are considered as part of the interventions for in-school youth drinking.

Alcohol Consumption Assessed by a Biomarker and Self-Reported Drinking in a Sample of Pregnant Women in the South of Europe: A Comparative Study.

(1) Background: Alcohol consumption during pregnancy is a major concern, particularly in Europe and North America. Its prevalence has so far been under-researched. In most studies, the determination of this consumption may be underestimated, as it is based on the information obtained from questionnaires rather than from biomarkers, which will provide a much more reliable approach. The main objective of this study was to compare the prevalence of consumption during pregnancy as assessed by a questionnaire and a hair biomarker. (2) Method: A cross-sectional study with a random sample of 425 pregnant women treated in public hospital consultations in Seville (Spain) and in the 20th week of their pregnancy, orally interviewed using an elaborated ad hoc questionnaire that evaluated variables of sociodemographic, obstetric, and alcohol consumption. Furthermore, the ethyl glucuronide metabolite (EtG) was tested on a hair sample in 252 pregnant women who agreed to facilitate it. Once the data obtained through the questionnaire and hair test were analyzed, the level of metabolites and self-reported alcohol consumption were compared. (3) Results: The prevalence of self-reported alcohol consumption (questionnaire) was 20.7%, and the real consumption (metabolite analysis) was 20.2%. In 16.8% of pregnant women who declared not consuming alcohol during their pregnancy, noticeable consumption was detected according to the metabolite test. No relevant level of variability in estimated alcohol consumption was detected in the biomarker with respect to the sociodemographic and obstetric variables studied. (4) Conclusions: The prevalence of alcohol consumption during pregnancy obtained through both questionnaires and metabolite analyses was similar and high. There is no association between consumption and sociodemographic factors in this sample. The determination of consumption through biomarkers allows for a more accurate approximation of the prevalence of consumption than estimated through questionnaires. Larger sample-sized studies are needed to determine consumption patterns and thus guide the adoption of more precise policies fostering abstinence from alcohol consumption since the preconception period.

Female adolescent sexual assault; a national review of 1014 consecutive cases

BackgroundSexual violence is common in contemporary society and disproportionally affects adolescents. In order to develop effective treatment, awareness and prevention strategies it is vital that we understand the epidemiology of adolescent sexual assault (SA). The aim of this study is to evaluate attendances by female adolescents to the national sexual assault treatment unit (SATU) network in the Republic of Ireland and compare these attendances with adult women accessing the service. MethodsThis is a cross-sectional study analysing the attendances of all adolescent female attendances at the 6 SATUs in the Republic of Ireland and comparing them with all adult female attendances between 1/1/2017 and 31/12/2022. ResultsThere were 1014 female adolescent attendances and 3951 female adult attendances over the timeframe studied. Adult attenders were more likely to attend within 7-days of the alleged assault compared with adolescent attenders (80.3% V 70.2% OR1.513 CI 1.35-1.697 p < 0.001). When compared with adult attenders, adolescent attenders were significantly more likely to disclose being assaulted outdoors (40.9% V 15.7% OR2.607 CI 2.346-2.898 p < 0.01), during the day (58.4% V 34.4% OR1.673 CI 1.565-1.790 p < 0.01), assaulted by a friend/family member (28.9% V 16% OR 1.812 CI1.603-2.049 p < 0.01) and less likely to have consumed alcohol prior to the incident (45.6% V 25.3% OR1.807 CI 1.653-1.975 p < 0.001). Physical injuries were less likely in adolescent attenders (30% V 35.5% OR0.845 CI 0.758-0.942 p = 0.02). ConclusionA comparison of the characteristics of adolescent and adult female sexual assault disclosures identifies differences regarding location of the incident, relationship to perpetrator and prevalence of alcohol consumption. Knowledge of these factors support appropriate tailoring of treatment, prevention and awareness strategies to help modify the impact and reduce the incidence of SA in the vulnerable adolescent cohort.

Alcohol consumption and associated factors among pregnant women attending antenatal care at governmental hospitals in Harari regional state, Eastern, Ethiopia

BackgroundAlcohol consumption during the pregnancy period is high despite the well-established evidence of its harmful effects on pregnancy and infant development. Early identification and behavioral modification are of great significance. This study aimed to assess the prevalence and associated factors of alcohol consumption among pregnant women attending antenatal care at governmental hospitals in the Harari regional state, Eastern Ethiopia.MethodFrom April 1/2022-May 1/2022, an institutional-based cross-sectional survey was conducted among 589 pregnant women attending antenatal care governmental hospitals in Harari regional state. A systematic random sampling technique was used to select study participants during the study period. Data were collected through face-to-face interview methods using AUDIT-C. The collected data were coded, entered into Epi-data data version 3.1, and analyzed by SPSS Version 26. Binary logistic regression was carried out to identify independent predictors of alcohol consumption at a 95% confidence level.ResultsFrom a total of 617 eligible participants, 589 participated in the study with a response rate of 95.46%. The overall prevalence of alcohol consumption among pregnant women in Harari regional state governmental hospitals was 21.2% (95% CI:17.8, 24.4). In multivariate analysis, single marital status (AOR = 5.18;95% CI (2.66,10.11), previous history of abortion(AOR = 4.07;95% CI(2.06,8.04), family history of mental illness (AOR = 4.79;95% CI (1.94,11.83), depression (AOR 2.79; 95%CI(1.35,5.76), and anxiety(AOR = 2.51; 95% CI (1.23, 5.12) were variables found to have a statistically significant association with alcohol consumption during pregnancy in Harari regional state governmental hospitals.ConclusionIn comparison to the majority of other research, the prevalence of alcohol usage during pregnancy was high in this study. This study observed that single marital status, previous history of abortion, family history of mental illness, depression, and anxiety were highly associated with alcohol consumption during pregnancy. Hence, responsible bodies working on mother and child health should try to mitigate or remove the above-mentioned risks when developing interventions.

Alcohol per capita and prevalence of alcohol exposed pregnancies: systematic review and meta-analysis

Abstract Background Alcohol is a teratogen that crosses the placenta. While studies have estimated the global burden of alcohol use in pregnancy, reliable and valid data on alcohol consumption during pregnancy in many countries is lacking. Alcohol consumption per capita (APC) data are available worldwide. This systematic review, by investigating the association between APC and alcohol consumption in pregnancy by country, aims to evaluate the accuracy of using APC data to predict the prevalence of prenatal alcohol exposure (PAE). Methods This study combines studies identified in a systematic review by Popova et al. 2017 and a systematic search of MEDLINE from 2015 through 6th October 2022, to identify additional papers. Papers identified in either search were on the prevalence of PAE or fetal alcohol syndrome (FAS). Two authors independently screened titles, abstracts, full-text articles and performed data extraction and quality assessment. APC data,per country, by year, was obtained from the World Health Organization (WHO) website. A meta-analysis, assuming a random effects model will be performed. Sensitivity analyses, including restricting by population, timing of exposure, time and method of ascertainment of alcohol consumption will be carried out. Results Of 24,935 PAE and 12,231 FAS prevalence articles identified, 400 PAE studies and 77 FAS studies met the inclusion criteria. Studies represent data from 1959-2020 from all 6 WHO regions, with APC between 0.012-14.78. Preliminary analysis suggests a statistically significant correlation between prevalence of alcohol consumption during pregnancy and APC. Conclusions Preliminary results from this study suggest that publicly available data on APC can be used to predict the population-based prevalence of alcohol use in pregnancy in different countries. Effective policies and interventions are required to reduce APC and thus, alcohol use in pregnancy and associated detrimental child health outcomes around the globe. Key messages • Knowing the prevalence of FAS and its main risk factor- prenatal alcohol use, will inform the setting of priorities for public health policy, public health initiatives, and health-care planning. • By investigating the association between alcohol intake in pregnancy and APC we will assess whether APC can predict alcohol intake in pregnancy.

The Association of Alcohol Use and Child-to-Parent Violence in Mexican Adolescents

Background: Addictions can modify the dynamics, communication, and establishment of assertive relationships in the family nucleus, situations that can cause different types of family violence. A phenomenon of special interest is child-to-parent violence or children’s violence toward their parents. This type of violence can be exercised physically (hitting, kicking, shoving), verbally (shouting, blackmailing and insulting) and economically (using a card, stealing money or belongings from the parents). Although is generally supported that child-to-parent violence may be associated with alcohol-induced aggressiveness and lack of control, there is less evidence of a possible differentiation regarding the sex of the parents. Objective: Analyze the relationship and effect of alcohol on child-to-parent violence according to the parents’ sex. Methods: This was a predictive study of 265 adolescents between 12 and 19 years of age. Data were collected from social networks using two self-applied instruments (the Alcohol Use Disorders Identification Test and the Conflict Tactics Scale: Parent-Child Version) programmed with the Survey Monkey® digital platform. Results: Of the adolescents studied, 66.8% had consumed alcohol at some time in their lives; of these, 6.6% had harmful consumption. A positive relationship was found between alcohol involvement scores and economic violence toward the mother and father. The former was supported by regression models where alcohol involvement predicted child-to-parent economic violence directed toward mothers and fathers. Conclusions: It is important to develop activities to prevent alcohol consumption as a risk factor for violence and to promote family integration in adolescents and their families.