Objective To discuss the incidence and risk factors of pressure ulcer in surgical patients of our hospital. Methods Totally 10 737 surgical patients were recruited.The patients were assessed by the Braden Scale.The incidence of pressure ulcer in patients with the Braden score lower than 18 was recorded.Besides, the data of patients with pressure ulcers on admission were also collected.All risk factors in patients with pressure ulcer were analyzed. Results The incidence rate of pressure ulcer in surgical patients was 0.54%.The incidence of pressure ulcer was highest in department of Neurosurgery(1.46%), followed by the department of Orthopedics(0.61%), which was significantly higher than other departments, the difference was statistically significant(P<0.05). Single factor analysis indicated that age, smoking, nutrition, diabetes, paralysis, and large, urinary incontinence, consciousness, operation situation, serum albumin, use of analgesics, presence of caregivers contributed to pressure ulcer, the difference was statistically significant(P<0.05). Multivariable logistic regression analysis showed that age, diabetes, paralysis, consciousness, albumin levels, use of analgesic, presence of caregivers were independent risk factors of pressure ulcers in patients. Conclusion There are many factors affecting the incidence of pressure ulcer, while age, diabetes, paralysis, consciousness, albumin levels, use of analgesic, presence of caregivers are independent risk factors of pressure ulcers. Key words: Pressure ulcer; Risk factors; Data collection