Presence Of Vaginitis Research Articles

The relationship between vaginal microenvironment and pelvic dysfunctional diseases in Chinese women: a systematic review and meta-analysis.

The aim of this review is to synthesize existing evidence on the combined effects of the vaginal microenvironment on pelvic dysfunctional diseases. This systematic review was conducted in accordance with the PRISMA guidelines. The PubMed, Embase, Cochrane Library, Web of Science, Wanfang, and China Knowledge Network (CNKI) databases were systematically searched up to January 2023 using the following MeSH terms: "pelvic organ prolapse", "stress urinary incontinence" and "vaginal microenvironment", "microenvironment", "vaginal cleanliness", "vaginitis", "lactobacillus" and other related keywords. Study methods were limited to case-control studies or cross-sectional studies. Quality assessment was performed using the Newcastle-Ottawa scale, and meta-analysis of the included literature was performed using Review Manager 5.3. A total of eight articles were included in this systematic review (SR) and meta-analysis (MA), which involved a total of 7298 study participants. The pooled results of this meta-analysis showed that the vaginal microenvironment (number of vaginal lactobacilli, leukorrhea cleanliness, and presence of vaginitis) were all statistically significantly associated with pelvic dysfunctional diseases in Chinese women. This review indicates that the vaginal microenvironment has an impact on the development of PFD in Chinese women. The protocol of this systematic review (SR) and meta-analysis (MA) has been registered in PROSPERO databases with the Registration number of CRD42023407251.

PSII-21 Vaginitis incidence and effects on fertility of beef females enrolled on estrus synchronization protocols using a controlled internal drug release (CIDR) device

Abstract Our objectives were to characterize the incidence of vaginitis caused by a controlled internal drug release (CIDR) device and its effects on fertility of beef females enrolled on estrus synchronization followed by timed-artificial insemination (TAI). A total of 1,097 mature cows and 215 heifers from 9 different locations were enrolled in the 7-d CO-Synch + CIDR synchronization protocol. At CIDR insertion, all females were inspected for any previous signs of vaginitis prior to enrollment in the experiment. As evidence of vaginitis, a CIDR score was determined at CIDR removal, and an AI plastic sheath score was also performed at TAI following a 1 to 4 system: 1=clean presenting no secretion; 2=clean presenting clear secretion; 3=presence of purulent secretion; 4=presence of purulent secretion and blood. Pregnancy status was determined by rectal ultrasonography approximately 40 days after TAI. The scores for CIDR and AI plastic sheath did not differ between cows and heifers. Of all females, 6% had a CIDR score of 1, 31% score 2, 56% score 3, and 7% score 4. Plastic sheath score was 1 for 16%, 2 for 62%, 3 for 15%, and 4 for 7% of females. Pregnancy rate to TAI differed between cows and heifers (P < 0.01), among locations (P < 0.001) and ranged from 36 to 66%; however, it was not influenced by CIDR score (P = 0.259) and plastic sheath score (P = 0.785). Pregnancy rate of females by different CIDR scores was 60%, 57%, 52%, and 46% for scores 1, 2, 3, and 4, respectively. Pregnancy rate of females by different AI plastic sheath score was 60%, 55%, 45%, and 48%, for scores 1, 2, 3, and 4, respectively. The presence of vaginitis caused by a CIDR does not influence pregnancy rates of TAI in beef females.

Новые подходы в комплексной терапии воспалительных заболеваний органов малого таза у женщин репродуктивного возраста

The objective: to study the efficacy of complex treatment of inflammatory diseases of the pelvic organs (vaginitis), occurring in conjunction with urinary tract infection (cystitis), with a combined medication of plant origin Tutukon produced by Miguel and Garriga, S. A. ("Grand medical Group AG", Spain/Switzerland) in women of reproductive age. Patients and methods. Were examined 60 women of reproductive age with the presence of vaginitis and associated cystitis. All the patients were divided into two clinical groups. In group I (control; n=30) treatment was carried out according to the standard scheme with the use of antimicrobial drugs, antispasmodics, local antiseptics for the sanitation of the vagina. In group II (study group; n=30) treatment was carried out according to the standard scheme with the inclusion of the drug Tutukon. All the patients were examined at 3-rd, 7-th, 10-th day of treatment and 30 days after discontinuation of therapy. Results. During the research was given the analysis of the dynamics of clinical and laboratory parameters in women of both groups before and after treatment. In patients of study group, the standard therapy which included Tutukon, the treatment was more effective than in patients of control group: a rapid onset of clinical effect, reducing the duration of the disease, a complete clinical response in 90% of cases versus 63%, alkalization of urine - pH 6.5±0.10, the absence of recurrence within 30 days after the end of therapy. Conclusion. Tutukon medicine is recommended for complex treatment of vaginitis, occurring in combination with cystitis in women of reproductive age. Key words: vaginitis, cystitis, dysuria, urine pH, Tutukon.

Simplicimonas-like DNA in vaginal swabs of cows and heifers cross-reacting in the real-time PCR for T. foetus

Cows on an alpine pasture were presented with severe signs of vaginitis. To rule out infection with Tritrichomonas foetus, vaginal swabs were taken and real-time PCR based on detection via fluorescence resonance energy transfer (FRET) probes and targeting the first internal transcribed spacer (ITS-1) of nuclear ribosomal DNA (rDNA) was performed. PCR was positive in 25 of totally 34 assessed cows. However, the melting profiles of the probes targeting the diagnostic PCR products differed from the T. foetus positive control. Subsequent sequencing of the amplicons revealed 91% identity to Simplicimonas sp. sequences deposited in GenBank™. Furthermore, there was no clear association between positive PCR result and presence of vaginitis. To investigate the distribution of this Simplicimonas-like organism in cows, more herds grazing on the same alpine pastures as well as unrelated cows were tested. In total, 133 cows and 16 heifers were sampled, 53 cows and 6 heifers even twice. Vaginitis was evident in 43 cows and 4 heifers. All-over-positivity of PCR was 44%, including nine tests performed on heifers. Melting peak analysis indicated Simplicimonas-like organisms in all positive samples. Culture attempts in bovine InPouch ™ TF failed. No association between a positive PCR result and the presence of vaginitis was found. This is, to the best of our knowledge, the first report on Simplicimonas-like DNA in vaginal swabs of female cattle. Our data suggest that when testing vaginal swabs of cattle by means of T. foetus PCR, false positive reactions due to Simplicimonas-like organisms may occur.

Martius Flap for Iatrogenic Rectovaginal Fistula: When to do a Diverting Stoma?

Aim of the work: To evaluate the outcome of RVF repair using Martius flap with and without diverting stoma. Patients and Method: Twenty six patients with RVF were divided into 2 groups, one without colostomy (group A) and the second with (group B). Results: Postoperative wound infection was 33% in group A & 9% in group B. Early failure in group A was 13% and 0% in group B, whereas late failure was 6.6% & 9%, in group A & group B, respectively. Conclusion: It is advised to perform pre-repair diverting stoma to improve the outcome in RVF with large defects, presence of vaginitis, or postradiation.

Pruritus vulvae as seen in dermatological practice.

Commonly the term pruritus vulvae is used as a diagnosis, though literally it describes only a symptom rarely seen without excoriation or dermatitis; seldom can the patient tell us which was the primary symptom. Unnecessary confusion results when the term is incorrectly applied, as in the presence of a distinctive dermatosis such as vulvar psoriasis or dermatomycosis. Dermatological experience minimizes this fault, which is commoner among general practitioners, gynecologists, and radiologists. There are various views on this disease, partly owing to the confusion of inaccurate terminology and partly to the viewpoints of the various specialists consulted by the patient, whose choice of physician has depended on the presence of vaginitis or discharge, urinary complaints, involvement of the perianal area, or extensive cutaneous inflammation. Because of such variations and because pruritus vulvae is fairly common and is frequently difficult to treat I have surveyed the literature of the past 10 years