Presence Of Suicidal Ideation Research Articles

Sleep disturbance and suicidal ideation among youth with depression

BackgroundSleep disturbance may exacerbate the risk of suicide among youth with depression, but whether this association is independent of psychopathology requires further study. MethodsThis cross-sectional study included 576 youths (13–25 years old) recruited from January 2022 to May 2023. The patients were first divided into two groups by the presence of suicidal ideation according to the Columbia-Suicide Severity Scale (C-SSRS). Sleep quality was assessed by the Athens Insomnia Scale (AIS) and mental health with the Hamilton Depression Rating Scale (HAMD) and Hamilton Anxiety Rating Scale (HAMA). Logistic regression was conducted to analyze the association between sleep disturbance and suicidal ideation, adjusted for depressive symptoms severity. ResultsThe suicidal ideation group exhibited more severe sleep disturbances, anxiety symptoms, and depressive symptoms than the non-suicidal ideation group. Pearson correlation showed that sleep disturbance (AIS) was significantly correlated with the severity of anxiety symptoms, depressive symptoms, and suicidal ideation. Logistic regression analysis revealed that the AIS factor “daytime dysfunction” (β = 0.145; OR = 1.156, 95 % CI: 1.02, 1.309; p = 0.023) was significantly associated with suicidal ideation after adjusting for demographic characteristics and depressive symptoms severity. LimitationsDue to the cross-sectional nature of the data, no causal inference can be made regarding the observed associations between sleep disturbance and suicidal ideation. ConclusionSleep disturbance, particularly in the realm of daytime dysfunction, is associated with increased suicidal ideation among depressed youth. Clinicians need to assess and manage sleep disturbance in the context of suicidal ideation for young depression patients.

Exploring Narcissism in Suicidal Ideation Using the Italian Version of the Guilt and Shame Proneness Scale.

Several theoretical and clinical observations lead to the hypothesis that pathological narcissism could be associated with suicide ideation due to the difficulty in regulating shame in a functional way. The present study investigated the roles of guilt, shame and rivalry in the relationship between pathological narcissism and suicidal ideation. A set of self-report questionnaires was completed by a sample of 936 Italian adults. These included the Italian version of the Guilt and Shame Proneness (GASP) scale, the Pathological Narcissism Inventory, the Beck Scale for Suicidal Ideation, and the Narcissism Admiration and Rivalry Questionnaire. A structural equation model that tested the factorial structure of the GASP and its invariance produced satisfactory results. Moreover, shame was a significant factor in the relationship between narcissism grandiosity and suicidal ideation. However, beta regression coefficients were low. These findings suggest that despite clinicians should consider the presence of suicidal ideation in patients with pathological narcissism and their maladaptive regulation of shame, the relationship between these variables is complex and deserve further investigation.

Brain and blood transcriptome profiles delineate common genetic pathways across suicidal ideation and suicide.

Human genetic studies indicate that suicidal ideation and behavior are both heritable. Most studies have examined associations between aberrant gene expression and suicide behavior, but behavior risk is linked to the severity of suicidal ideation. Through a gene network approach, this study investigates how gene co-expression patterns are associated with suicidal ideation and severity using RNA-seq data in peripheral blood from 46 live participants with elevated suicidal ideation and 46 with no ideation. Associations with the presence of suicidal ideation were found within 18 co-expressed modules (p < 0.05), as well as in 3 co-expressed modules associated with suicidal ideation severity (p < 0.05, not explained by severity of depression). Suicidal ideation presence and severity-related gene modules with enrichment of genes involved in defense against microbial infection, inflammation, and adaptive immune response were identified and investigated using RNA-seq data from postmortem brain that revealed gene expression differences with moderate effect sizes in suicide decedents vs. non-suicides in white matter, but not gray matter. Findings support a role of brain and peripheral blood inflammation in suicide risk, showing that suicidal ideation presence and severity are associated with an inflammatory signature detectable in blood and brain, indicating a biological continuity between ideation and suicidal behavior that may underlie a common heritability.

Teacher Experience of Guidance and Counseling in Treating Youth with Cyberbullying Case

Background: Cyberbullying in adolescents may cause depression, decreased academic achievement, withdrawal from the environment, family and the presence of suicidal ideation. The success of teachers in dealing with cyberbullying is unknown.Objective: To explore the Guidance and Counseling Teachers experience in dealing with adolescents with cyberbullying incidents.Methods: This study used a qualitative descriptive approach with a phenomenological approach and data were collected through in-depth interviews with 8 Guidance and Counseling Teachers who deal with adolescents with cyberbullying incidents. Data analysis in this study used the Colaizzi method.Results: In this study, there were five essential themes in this research including cyberbullying is not a serious problem, various problems faced in dealing with cyberbullying, emotional responses to cyberbullying victims, cyberbullying victims are weak emotional mentality students and lack of coordination between parents, teachers subjects and Guidance and Counseling teachers.Conclusion: The problem of cyberbullying has considered as unserious problem and there is a lack of coordination between parents, subject teachers and guidance and counseling teachers. So that special training is needed to deal with cyberbullying, there are guidelines, clear cyberbullying prevention strategies and the existence of government agencies that specifically handle cyberbullying case.

Prevalence and correlates of suicidal ideation in the general public during the fifth wave of COVID-19 pandemic in Hong Kong.

Literature reveals increased suicidal ideation in the general population during pandemic. However, few COVID-19 studies comprehensively assessed factors associated with suicidal ideation, and mixed findings were observed. We aimed to examine prevalence and correlates of suicidal ideation in general public during the peak of fifth COVID-19 wave in Hong Kong based on a broad array of relevant measures. This survey assessed 14,709 community-dwelling adults during March 15-April 3, 2022. Comprehensive assessment was administered including socio-demographics, pre-existing mental/physical morbidity, mental-health symptoms, resilience, loneliness, coping strategies, and pandemic-related factors. Presence of suicidal ideation was evaluated by ratings of item 9 on Patient-Health-Questionnaire-9. A total of 2,249 (15.3%) participants exhibited suicidal ideation. Multivariable-regression analysis found that being single and unemployed, pre-existing mental disorder, more severe depressive and anxiety symptoms, higher levels of loneliness and engagement in avoidant coping were significantly associated with suicidal ideation. Conversely, attaining tertiary educational level or above, greater resilience and adopting problem-focused coping were associated with lower likelihood of suicidal ideation. Although univariate-analyses revealed that a number of pandemic-related factors were linked to suicidal ideation, none remained significant in the multivariable model. A significant proportion of people experienced suicidal ideation during the peak of fifth COVID-19 wave. Risk and protective factors identified would facilitate early identification of high-risk individuals and provision of targeted interventions to minimize suicidal ideation and risk of self-harm. Caution should be exercised due to study limitations of a cross-sectional design which precluded establishing causality among variables, and reliance on self-reported data.

The mediating effect of dysmorphic concern in the association between avoidant restrictive food intake disorder and suicidal ideation in adults

BackgroundReflecting on the existing literature on suicidal ideation and Avoidant/Restrictive Food Intake Disorder (ARFID), this article investigates the complex relationship between them, hypothesizing about the possibility of dysmorphic concerns, being a mediator linking ARFID to suicidal ideation.MethodsUsing a snowball sampling approach, a survey was created on Google Forms and circulated across messaging applications and social media networks (WhatsApp, Instagram, Messenger). The sample involved 515 participants recruited between February and March 2023. The questionnaire included the following scales: Nine-items Avoidant/Restrictive Food Intake Disorder screen (NIAS), Dysmorphic Concern Questionnaire (DCQ), and Columbia-Suicide Severity Rating Scale (C-SSRS). When filling the questionnaire, respondents were warned that they can experience distress when answering certain questions and received information about mental health services. Five hundred fifteen adults participated in this study, with a mean age of 27.55 ± 10.92 years and 60.1% females.ResultsAfter adjusting over potential confounders (i.e., age, education, marital status, and household crowding index), analyses showed that dysmorphic concerns fully mediated the association between avoidant restrictive eating and suicidal ideation. Higher avoidant restrictive eating was significantly associated with more dysmorphic concerns, and higher dysmorphic concerns were significantly associated with the presence of suicidal ideation. Finally, avoidant restrictive eating was not significantly associated with suicidal ideation.ConclusionThis study highlights the potential indirect link between ARFID and suicidal ideation mediated by dysmorphic concerns. While no direct connection was observed between ARFID and suicidal ideation, the presence of dysmorphic concerns appeared to be a crucial factor in amplifying the risk of suicidal ideation in individuals with ARFID. This emphasizes the importance of addressing dysmorphic concerns alongside ARFID treatment to enhance mental health interventions and outcomes.

Characterization of Psychiatric Inpatients: The Role of Gender Differences in Clinical and Pharmacological Patterns.

Severe mental disorders that require hospitalization are disabling conditions that contribute to the burden of mental diseases. They pose increased clinical challenges and highlight the need to thoroughly explore variables emerging from daily clinical practice. In this study, we assessed to what extent gender differences may characterize a large population of psychiatric inpatients. We conducted a cross-sectional study in 2 Italian teaching medical centers, which included 2358 patients who were consecutively admitted to the psychiatric emergency units. We explored and characterized gender differences for variables such as prevalence of psychiatric diagnosis, presence of suicidal ideation, suicide attempts, age at onset of psychiatric illness, presence of substance or alcohol abuse, length of stay, number of hospitalizations, presence of involuntary admission, type of discharge from the hospital, and pharmacological treatment at discharge. Female patients were primarily diagnosed with bipolar disorder or personality disorders. Female patients had a significantly higher prevalence of lifetime suicide attempts (23.1% vs. 16.5%, P<0.001) and a longer length of hospitalization (11.43±10.73d vs. 10.52±10.37d, t=-2.099, gl=2356, P=0.036) compared with male patients. Male patients had more involuntary admissions (25.1% vs. 19.7%, χ2=9.616, gl=1, P=0.002), more use of illicit substances (34.1% vs. 20.9%, χ2=51.084, gl=1, P<0.001), and higher rates of alcohol abuse (21.3% vs. 14.7%, χ2=17.182, gl=1, P<0.001) compared with female patients. Finally, antidepressants and lithium were prescribed more frequently to the female patients, whereas other mood stabilizers were more often prescribed to the male patients. Our real-world results highlighted gender differences among patients with severe mental disorders admitted to psychiatric units, and suggest further investigations that may help in understanding trajectories accompanying disabling clinical conditions.

FC43: Particularities of late-life psychosis: from epidemiology to treatment option

Objective:Psychotic disorders are not infrequent in late life and involve massive costs to society, affecting individuals and their caregivers. The epidemiology of late-life psychosis remains imprecise and despite its high prevalence, it remains a diagnostic and treatment dilemma. The aim of this article is to review the current literature regarding late-onset psychosis and whether it is recognized as a clinical entity on itself, differing from early-onset psychosis.Methods:Review of the most recent literature regarding late-onset psychosis its clinical and epidemiological particularities. The research was carried out through the PubMed and UptoDate databases, using the terms “late-onset psychosis”, “late-life psychosis”, “dementia” and “elderly”.Results:Late-life psychotic disorders may originate in an intricate interaction between several biological, psychological, social, and environmental factors. These may include functional status, other physical diseases, hospitalizations, physical activity, and stability of care. Some authors refer that older age, and the presence of suicidal ideation were associated with incident late-life psychosis. Assuming the significant load associated with psychotic disorders in late life, their assessment should identify the potential causes and distinguish predictive factors. Treatment should include a combination of nonpharmacological approaches and psychotropic medications, used cautiously.Conclusion:Late-life psychosis differs from early-onset psychosis on several characteristics. The treatment must be directed towards the cause and adapted to each individual. Non-pharmacologic interventions are frequently used as first line treatment, and pharmacotherapy must be used carefully. The crescent number of senior population must alert to this entity and the specificity of its approach.

Investigation of the Relationship of Suicidal Ideation and Suicide Attempt History with Early Maladaptive Schemas in Individuals with Major Depressive Disorder

Objective: We aimed to examine the relationship between the presence of suicidal ideation and attempt history and maladaptive schemas in individuals with major depressive disorder.&#x0D; Materials and methods: The experimental group consisted of 28 individuals were diagnosed with major depressive disorder, had a history of suicide attempt and active suicidal ideation. 26 individuals who did not have active suicidal ideation and any history of suicide attempt constitute the control group. Sociodemographic data form, Beck Anxiety Scale, Beck Depression Scale, Beck Suicidal Ideation Scale and Young Schema Scale-Short Form-3 were administered to the participants.&#x0D; Results: The groups differed in terms of all scale scores (p

Suicidal ideation in female individuals with fibromyalgia and comorbid obesity: prevalence and association with clinical, pain-related, and psychological factors.

Individuals with fibromyalgia report alarming levels of suicidal ideation, and comorbidity with other chronic health conditions such as obesity-a risk factor for suicidal ideation per se-could further complicate the clinical picture. The aim of this study is to determine, in a sample of women with fibromyalgia and comorbid obesity, the prevalence of suicidal ideation and to evaluate clinical, pain-related and psychological factors associated with suicidal ideation. In total, 156 female individuals with fibromyalgia and obesity were recruited and completed a series of self-report measures that assessed (i) the level of pain intensity, (ii) depressive symptomatology, (iii) sleep quality, and (iv) pain catastrophizing. Suicidal ideation was evaluated by item #9 of the Beck Depression Inventory. In addition, information regarding previous suicide attempts and current opioid use was collected. 3n sum, 7.8% of participants reported presence of suicidal ideation. According to the results of the multiple logistic regression, depressive symptomatology, sleep quality, and pain catastrophizing were associated with the presence of suicidal ideation. The presence of suicidal ideation in our sample was significantly associated with depressive symptomatology, sleep quality, and pain catastrophizing. Our findings are the first to suggest a unique (ie, independent of depressive symptomatology, and sleep quality) association between pain catastrophizing and suicidal ideation in the context of fibromyalgia and comorbid obesity. In order to prevent and reduce suicidal ideation, these factors should be assessed and targeted in interventions for pain management. Future research should investigate the extent to which addressing depressive symptoms, sleep quality, and pain catastrophizing reduces suicidal ideation.

Association of interleukin-6 with suicidal ideation in veterans: a longitudinal perspective.

Studies showing associations between inflammation in suicide are typically cross-sectional. Present study investigated how cytokine levels track with suicidal ideation and severity longitudinally. Veterans with a diagnosis of major depressive disorder (MDD) with or without suicide attempt history (MDD/SA n = 38, MDD/NS n = 41) and non-psychiatric non-attempter controls (HC n = 33) were recruited, MDD/SA and HC groups were followed longitudinally at 3 months and 6 months. Blood plasma was collected and processed using Luminex Immunology Multiplex technology. Significant differences in depression severity (BDI) and suicidal ideation severity (SSI) were observed across all groups at study entry, wherein MDD/SA group had the highest scores followed by MDD/NS and HC, respectively. Cytokines IL-1β, IL-4, TNF-α, IFN-γ, and IL-6 were examined at study entry and longitudinally, with IL6 levels differing significantly across the groups (p = 0.0123) at study entry. Significant differences in changes in cytokine levels between depressed attempters and the control group were detected for IL-6 (interaction F1,91.77 = 5.58, p = 0.0203) and TNF-α (F1,101.73 = 4.69, p = 0.0327). However, only depressed attempters showed a significant change, in IL-6 and TNF-α levels, decreasing over time [IL-6: b = -0.04, 95% CI = (-0.08, -0.01), p = 0.0245 and TNF-α: b = -0.02, 95% CI = (-0.04, -0.01), p = 0.0196]. Although IL-6 levels were not predictive of suicidal ideation presence [OR = 1.34, 95% CI = (0.77, 2.33), p = 0.3067], IL-6 levels were significantly associated with suicidal ideation severity (b = 0.19, p = 0.0422). IL-6 was not associated with presence of suicidal ideation. IL-6 however, was associated with severity of ideation, suggesting that IL-6 may be useful in clinical practice, as an objective marker of heightened suicide risk.

Perceived Stigmatization among Dermatological Outpatients Compared with Controls: An Observational Multicentre Study in 17 European Countries

Perceived stigmatization places a large psychosocial burden on patients with some skin conditions. Little is known about the experience of stigmatization across a wide range of skin diseases. This observational cross-sectional study aimed to quantify perceived stigmatization and identify its predictors among patients with a broad spectrum of skin diseases across 17 European countries. Self-report questionnaires assessing perceived stigmatization and its potential predictors were completed by 5,487 dermatology outpatients and 2,808 skin-healthy controls. Dermatological diagnosis, severity, and comorbidity were clinician-assessed. Patients experienced higher levels of perceived stigmatization than controls (p &lt; 0.001, d = 0.26); patients with psoriasis, atopic dermatitis, alopecia, and bullous disorders were particularly affected. Multivariate regression analyses showed that perceived stigmatization was related to sociodemographic (lower age, male sex, being single), general health-related (higher body mass index, lower overall health), disease-related (higher clinician-assessed disease severity, presence of itch, longer disease duration), and psychological (greater distress, presence of suicidal ideation, greater body dysmorphic concerns, lower appearance satisfaction) variables. To conclude, perceived stigmatization is common in patients with skin diseases. Factors have been identified that will help clinicians and policymakers to target vulnerable patient groups, offer adequate patient management, and to ultimately develop evidence-based interventions.

Knowledge, Attitude, and Perception of Depression as a Predictor of Suicidal Ideation Among Undergraduate Students In Private University

This paper explores the relationship between knowledge, attitude, and perception of depression and its potential role as a predictor of suicidal ideation among undergraduate students at Babcock University. Suicide rates among young adults have been a growing concern, and understanding the factors contributing to suicidal ideation is crucial for developing effective prevention strategies. The study employs a quantitative research design and collects data through a structured questionnaire administered to a sample of undergraduate students. The questionnaire assesses participants' knowledge of depression, attitudes toward mental health, perception of depression, and the presence of suicidal ideation. The findings revealed that; Undergraduate students have positive knowledge of depression as a predictor of suicidal ideation with an average of 60.7% which is below expectation. There is a negative level of attitude towards depression as a predictor of suicidal ideation among the students with an average of 48%. There is a positive perception of undergraduate students about depression as a predictor of suicidal ideation with an average of 75.1%. There is a significant and positive relationship between depression and suicidal ideation with an average of 68.5%.&#x0D; Moreover, individuals with lower levels of knowledge, negative attitudes, and misconceptions about depression are more likely to experience suicidal ideation. The study highlights the importance of targeted educational programs that enhance mental health literacy, promote positive attitudes toward mental health, and challenge misconceptions surrounding depression. Implementation of such interventions can potentially reduce the prevalence of suicidal ideation among undergraduate students and foster a more supportive campus environment. Further research is warranted to explore additional factors that contribute to suicidal ideation and to validate the effectiveness of targeted interventions in reducing the risk of suicide among young adults.

Longitudinal investigation of the presence of different trajectories and associated health and socio-economic determinants, for participants who report suicidal ideation within a community-based public health survey

ObjectiveGiven the paucity of evidence-based research investigating different suicidal ideation profiles and trajectories, this project sought to investigate health and socio-economic factors associated with the presence of suicidal ideation and...

Associations between sleep complaints, suicidal ideation and depressive symptoms among adolescents and young adults in Greece.

Depression prevalence increases significantly during adolescence/early adulthood. Depression in youth may present suicidal ideation, while suicide represents the leading cause of death in this age group. Moreover, adolescents/young adults frequently report sleep complaints that may partially be due to depressive symptoms. Studies on the associations between depression, sleep complaints and suicidality in this age group are limited. We aimed to examine associations between depressive symptoms, sleep complaints and suicidal ideation in a large (n = 2771), representative sample of adolescents (age: 15-17 years, n = 512) and young adults (age: 18-24 years, n = 2259) from the general population in Greece. A telephone structured questionnaire was administered. Depressive symptoms were assessed using the modified Patient Health-7 questionnaire score, while presence of suicidal ideation and sleep complaints were assessed using the ninth and third question of Patient Health-9 questionnaire, respectively. Mediation logistic regression analysis revealed significant direct paths from depressive symptoms to sleep complaints (odds ratio [OR] 1.22, 95% confidence interval [CI] 1.19-1.24; OR 1.21, 95% CI 1.18-1.24) and suicidal ideation (OR 1.18, 95% CI 1.14-1.22; OR 1.18, 95% CI 1.14-1.22), as well as sleep complaints and suicidal ideation (OR 1.82, 95% CI 1.32-2.50; OR 1.91, 95% CI 1.33-2.76) in the total group and in young adults, respectively, but not among adolescents. Moreover, we detected a significant indirect effect of depressive symptoms on suicidal ideation mediated by sleep complaints (18.8%) in young adults. These findings support the hypothesis that treatment of sleep disturbances among youth with depression may independently further reduce suicidal risk.

Variability in suicidal ideation during treatment for individuals at clinical high risk for psychosis: The importance of repeated assessment.

Suicide risk is elevated among individuals at clinical high risk for psychosis (CHR-P). The current study examined variability in suicidal ideation during treatment for individuals at CHR-P. A retrospective chart review was used to examine the course of suicidal ideation during 16 sessions of individual psychotherapy for 25 individuals at CHR-P. Suicidal ideation was reported by 24% of participants at session 1 and 16% at session 16, with minimal within-subject change in the presence of suicidal ideation across the two time points. However, a more fine-grained investigation at each session indicated that 60% of individuals at CHR-P experienced suicidal ideation at least once during treatment. Additionally, there was great variability in suicidal ideation both within and between participants over the course of the 16 sessions. These findings highlight the importance of repeated assessment when examining suicidal ideation as a treatment outcome for individuals at CHR-P.

Preventing comorbidity between distress and suicidality: a network analysis

Suicidality among individuals between 10 and 35 years of age may be poised to exert massive burdens on society through decreased economic productivity and increased incidence of chronic physical conditions in the individuals’ later years, thereby necessitating early prevention of suicide. While research suggests that the pathway to suicidality may begin from episodes of psychological distress, such pathway may involve complex interplays between intermediary psychiatric symptoms and external stimuli that are not easily delineated through conventional means. This study applies the network approach to psychopathology to elucidate this complexity. Comorbidity between psychological distress and suicidality in 1968 community-dwelling individuals is analyzed with regularized partial correlation networks to identify their bridge symptoms and links. Temporal relationships between symptoms are analyzed through temporal symptom network formed from 453 individuals who completed subsequent follow-up surveys. Network analysis shows that feelings of hopelessness and the presence of suicidal ideation are the strongest bridge symptoms in the comorbidity symptom network, and form the only prominent link that bridges psychological distress and suicidality. Effects of sleep troubles, anxiety, and poor social relationships on suicidal ideation appear to be mediated by hopelessness. The same observations hold among individuals with and without diagnoses of psychiatric disorders, as well as young people (10–24 year-olds) and young adults (25–35 year-olds). The edge between hopelessness and suicidal ideation remains the strongest bridge link after controlling for effects of symptoms from the previous time point. Findings here provide an evidence base for both professional training in caregiving professions as well as gatekeeper training in community members to emphasize more on how to effectively recognize hopelessness, and instill hope, in young people and young adults for various types of distress.

Lower thyroid stimulating hormone concentrations linked to suicidal ideations among individuals with anxiety and mood disorders

IntroductionSuicidal behavior is quite common in individuals with anxiety and mood disorders (AMD). One of the coexistence factors in suicidal behavior is thyroid dysfunction, however the results are still controversial (Shen et al. J Affect Disord 2019;(1)180-185; Zhou et al., Transl Psychiatry. 2021;11(1):97). The role of thyroid function in suicidal ideation among individuals with comorbid AMD have not been thoroughly investigated.ObjectivesThe aim of this cross-sectional study was to identify potential associations between thyroid function and suicidal ideation in a sample of individuals with anxiety and mood disorders.MethodsThis exploratory study comprised 77 consecutive individuals with AMD (age range 18-73 years, 76% were females) attending the Psychiatry Day care unit. All individuals have been evaluated for current psychiatric diagnoses, suicidal ideation using the Mini International Neuropsychiatric Interview [M.I.N.I. 7.0.2]) as well as for socio-demographic factors and for current psychotropic medication use. Severity of depression and anxiety symptoms have been evaluated using the Patient Health Questionnaire-9 (PHQ-9) and the General Anxiety Disorder-7 (GAD-7). The biochemical blood tests were performed for the concentrations of thyroxine (FT4), triiodothyronine (FT3) and thyroid stimulating hormone (TSH). The univariate and multivariable logistic regression analyses were used to assess the association between biochemical parameters and suicidal ideation.ResultsOf all study individuals with AMD – 56% have been identified as having current SI. There were not significant differences according to age, gender, education, BMI, smoking, depression and anxiety symptoms and current psychotropics use between SI and non-SI individuals. Serum FT4, FT3 and TSH concentrations were within normal range. However individuals with SI had significantly lower TSH concentrations in comparison to the non-SI (1.54 (0.77) vs. 2.04 (1.22) IU/L, respectively; p = 0.049), without significantly differences in FT4 and FT3 concentrations. A multiple logistic regression, adjusting for sociodemographic factors and severity of mental symptoms revealed, that non-SI individuals with AMD were likely to have higher TSH levels than SI (odds ratio = 2.15 (95% CI 1.10–4.22; p = 0.027).ConclusionsAmong individuals with AMD, lower levels of TSH concentrations have been associated with presence of suicidal ideation, independently of sociodemographic factors and severity of depression and anxiety.Disclosure of InterestV. Liaugaudaitė Grant / Research support from: European Union (project No P-PD-22-150) under the agreement with the Research Council of Lithuania (LMTLT)., A. Podlipskytė: None Declared, J. Burkauskas Consultant of: Cronos, N. Mickuvienė: None Declared, V. Adomaitienė: None Declared, E. Zauka: None Declared, V. Steiblienė: None Declared

ОСОБЕННОСТИ АДАПТАЦИИ МОЛОДЫХ ЛЮДЕЙ К НОВЫМ УСЛОВИЯМ ОКРУЖАЮЩЕЙ СРЕДЫ ПРИ СМЕНЕ МЕСТА ЖИТЕЛЬСТВА

The purpose of the work was to identify patterns of adaptation of young people to new environmental conditions when changing their place of residence. The study was carried out from September 2021 to June 2022, with the participation of134 people, 32 men and 102 women aged 18–20, first-year students of state universities in Volgograd. The gender, age, place of birth and place of residence of the respondents before entering the university were taken into account. To assess the level of systemic maladjustment, in terms of psychological, psychophysiological and psychosomatic symptoms of extreme tension of the body, a blank test by I.N. Gurvich, developed at the Psychoneurological Research Institute. V.M. Ankylosing spondylitis in1992. Manifestations of a stress reaction (Giessen questionnaire of somatic complaints) and anxiety-depressive disorders (HADS scale) were taken into account, and the presence of suicidal ideation was determined –modulo suicidal ideas of the Columbian Suicidal Seriousness Scale (C-SSRS). The functional status, in relation to the stress resistance of the subjects, was assessed by the level of the general nonspecific reactivity of the organism. As a result of the studies performed, it was determined that the maximum development of systemic maladjustment, at the time of passing the second examination session, is characteristic of male students who arrived to study in Volgograd from other regions of Russia. Throughout the spectrum of the studied symptoms of disa-daptation, both in the somatic (headaches, pains in the stomach, heart, abdomen) and in the mental (insomnia, physical fatigue, depression, suicidal ideation) sphere, their prevalence in groups of non-indigenous students is characteristic. residents of the Volgograd region, which is especially pronounced in men. In addition, male students, representatives of other regionsofRussia are characterized by a high level of general non-specific reactivity, indicating their low stress resistance, and men –the natives of the Volgograd region, in general, are characterized by an averagelevel of general non-specific reactivity of the organism.Women –participants in the study, both indigenous and non-indigenous residents of the Volgograd region, are characterized by a high level of non-specific reactivity, which implies an increasedstress reactivity of the body, and, accordingly,a risk of systemic maladaptation.

Suicidal Ideation and Its Associated Factors in Medical, Dental, and Pharmacy Students: A Cross-Sectional Study during COVID-19 Pandemic.

This study is aimed at comparing the prevalence of suicidal ideation among Iranian medical, dental, and pharmacy students and determining the demographic and basic characteristics and mental and psychological issues associated with suicidal ideation in these students. This cross-sectional online survey was conducted during the 2020-2021 academic year on medical, dental, and pharmacy students studying at the Tehran University of Medical Sciences (TUMS). The questionnaire consisted of six sections: Beck Hopelessness Scale (BHS), General Health Questionnaire (GHQ), Perceived Stress Scale (PSS), UCLA loneliness scale, Maslach Burnout Inventory-Student Survey (MBI-SS), and a questionnaire that was designed to evaluate students' family history, current psychological status, and basic and demographic characteristics. In total, 419 students participated in our study, with 133 (31.7%) being medical students, 85 (20.3%) being pharmacy students, and 201 (48%) being dental students. In our study, the prevalence of suicidal ideation was 32%. Family history of psychological issues (OR = 2.186, P =0.012), current or past smoking (OR = 2.155, P = 0.01), parents not living together (OR = 2.512, P = 0.046), and satisfaction with the current field (OR = 0.51, P < 0.001) were all independently associated with the presence of suicidal ideation. Also, higher scores in BHS (OR = 1.167, P < 0.001), PSS (OR = 1.081, P = 0.001), and UCLA loneliness scale (OR = 1.057, P < 0.001) were independently associated with a higher risk of suicidal ideation. The prevalence of suicidal ideation among Iranian medical, dental, and pharmacy students is relatively high and has increased during recent years, which needs emergent action.