Presence Of Sexual Dysfunction Research Articles

Percutaneous Tibial Nerve Stimulation's Impact on Sexual Function in Female Patients with Neurogenic Detrusor Overactivity, Sexual Dysfunction, and Multiple Sclerosis.

Background/Objectives: Multiple sclerosis (MS) frequently results in both urinary and sexual dysfunction, which significantly impairs quality of life. Conventional treatments for bladder dysfunction often prove insufficient, leading to the exploration of alternative therapies such as percutaneous tibial nerve stimulation (PTNS). This study aimed to assess the impact of PTNS on sexual function and bladder symptoms in female MS patients with neurogenic detrusor overactivity (NDO) and female sexual dysfunction (FSD). Methods: A total of 65 female MS patients with NDO were evaluated and underwent 12 weeks of standardized PTNS treatment. Sexual function was assessed using the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale-Revised (FSDS-R), while bladder symptoms were evaluated using the OAB-v8 questionnaire. Participants were grouped based on the presence of sexual dysfunction and distress and compared to a control group of 20 patients who declined PTNS. Results: Significant improvements were observed in FSFI scores across multiple domains (desire, arousal, lubrication, orgasm, satisfaction, and pain) in the treatment groups (p < 0.05). Additionally, 58.46% of patients showed positive responses to PTNS regarding overactive bladder symptoms (OAB-v8 score), while the control group showed no significant changes. Conclusions: PTNS appears to be an effective therapeutic option for improving sexual function and urinary symptoms in female MS patients with NDO and FSD, offering a promising non-invasive alternative for managing these conditions.

Testosterone therapy for functional hypogonadism in middle-aged and elderly males: current evidence and future perspectives.

Population aging is a global phenomenon driving research focus toward preventing and managing age-related disorders. Functional hypogonadism (FH) has been defined as the combination of low testosterone levels, typically serum total testosterone below 300-350 ng/dL, together with manifestations of hypogonadism, in the absence of an intrinsic pathology of the hypothalamic-pituitary-testicular (HPT) axis. It is usually seen in middle-aged or elderly males as a product of aging and multimorbidity. This age-related decline in testosterone levels has been associated with numerous adverse outcomes. Testosterone therapy (TTh) is the mainstay of treatment for organic hypogonadism with an identifiable intrinsic pathology of the HPT axis. Current guidelines generally make weak recommendations for TTh in patients with FH, mostly in the presence of sexual dysfunction. Concerns about long-term safety have historically limited TTh use in middle-aged and elderly males with FH. However, recent randomized controlled trials and meta-analyses have demonstrated safe long-term outcomes regarding prostatic and cardiovascular health, together with decreases in all-cause mortality and improvements in various domains, including sexual function, body composition, physical strength, bone density, and hematopoiesis. Furthermore, there are numerous insightful studies suggesting additional benefits of TTh, for instance in cardio-renal-metabolic conditions. Specifically, future trials should investigate the role of TTh in improving symptoms and prognosis in various clinical contexts, including sarcopenia, frailty, dyslipidemia, arterial hypertension, diabetes mellitus, fracture risk, heart failure, stable angina, chronic kidney disease, mood disorders, and cognitive dysfunction.

Prevalence of sexual disorders in relapsing-remitting multiple sclerosis patients depending on various risk factors

Objective. Multiple sclerosis is a perilous, disabling, physically as well as mentally, demyelinating disease of the central nervous system. This work aims to evaluate prevalence of sexual dysfunctions and their correspondence with non- and disease related risk factors, as well as with MRI findings in patients with relapsing-remitting multiple sclerosis. Results. Based on conducted multifactorial analysis, the most prominent risk factor associated with presence of sexual dysfunctions in in patients with relapsing-remitting multiple sclerosis was depression. Sexual dysfunctions are tied to cognitive deficit, in general and in separate domains, particularly in memory, executive functions and language. Considering disease-related agents, sensory and motor deficits are linked to the development of sexual dysfunctions in case of relapsing-remitting multiple sclerosis. Among non-disease-related factors, unemployment, marital status, level of education and tobacco smoking are affecting sexual dysfunctions’ severity. According to the MRI, frontal lobe and corpus callosum and periventricular area were affected more often comparing to other brain regions in case of sexual dysfunctions. Conclusions. Patients suffering from relapsing-remitting multiple sclerosis encounter secondary and tertiary sexual dysfunctions. Knowing all struggles of MS, patients should be offered more nuanced management options that will improve their quality of life on a deeper level.

(179) Sexual Dysfunctions in Infertile Tunisian Women

Abstract Introduction Once perceived as a source of pleasure and enjoyment, sexuality has evolved for infertile couples, focusing primarily on a purely procreative objective. Infertility has a direct impact on a woman's sex life, calling into question her femininity and causing significant alterations in the components of her sexual response. Objective The aims of our study were to assess the frequency of sexual dysfunction in Tunisian women facing infertility and to identify the aspects of their sexuality most affected. Methods This was a prospective, cross-sectional, and descriptive study, including a sample of 200 Tunisian infertile women, followed up in a Tunisian Assisted reproduction center over a three-month period, from November 24, 2022 to February 24, 2023. To assess the different dimensions of sexuality in infertile women, we used the Arabic version of the FSFI (female sexual function index) Results The mean age of our women was 30 ± 4 years. The majority had a university educational level (80%), an urban origin (87%), an average socio-economic level (63%), and no medical or gynecological surgery history (62%). Most partners (67%) had no sexual dysfunction (SD). The most frequent male SD was premature ejaculation, observed in 14% of cases. As regards the etiology of infertility, most cases were classified as unexplained (28%), while the remainder were linked to female causes, dominated by PCOS (40%). The majority of women had initially discussed the subject of sexuality (72%) with their partners. In our sample, the mean FSFI score was 20.74, with extremes ranging from 2 to 35.4. The prevalence of female sexual dysfunction (FSD) was 82%. The areas most affected were sexual satisfaction (50%), reaching orgasm (45%), as well as lubrication (44%) and arousal (44%). Lower educational level, secondary infertility, contraceptive use, and a long history of fertility treatment as well as the presence of sexual dysfunction in the male partner, were found to be associated with sexual dysfunction in women suffering from infertility, yet no significant correlation was established. Conclusions Infertility is associated with high rates of sexual dysfunction. Thorough counseling and continuing support of infertile women is therefore indicated. Disclosure No.

Sexual dysfunction in Egyptian patients with migraine

BackgroundMigraine is believed to affect over 20% of people at some point in their lives. The presence of sexual dysfunction in migraine sufferers can cause lack of self-confidence and divorces. The aim of this work is to study sexual dysfunction in migraine headache patients.MethodsThe study was carried out at Tanta University Hospital. The study included married patients who visited our hospital clinic and have had episodic or chronic migraine headaches and another group of age and sex matched healthy subjects will be recurited as a control group. Our interview includes questions for disease duration, severity and frequency of headache attacks and attack duration. questionnaire. the Arabic Version of the Migraine Disability Assessment Scale and Beck depression inventory. Sexual function will be evaluated by an Arabic version of Arizona sexual experience scale.ResultsThe ASEX score showed high significant changes between migraine patients and healthy subjects. These changes were reconfirmed when comparing male patients to healthy subjects or female patients to healthy subjects.Despite there was no significant difference regarding total ASEX score between bot male and female patients with migraine there was significant differences in the items of derive, erection/lubrication and satisfaction between them. In patients with migraine the total ASEX score was correlated with the MIDAS, Beck depression inventory, Beck anxiety inventory; but not with the age of patients or headache duration.ConclusionsSexual dysfunction is a common finding in migrine patients which is poorly evaluted in the clinical sitting.

(209) Sexual Knowledge, Attitude and Practices in Women Attending OBG Out Patient Department and Its Effect on Sexual Dysfunctions

Abstract Introduction In India, despite significant advances in the prevention and treatment of sexual dysfunctions, the majority of these have focused on male sexual dysfunction disorders. There is still a paucity of literature that adequately explains the relationship between sexual knowledge and attitudes of women and female sexual dysfunctions. Furthermore, physiological events such as pregnancy, childbirth, breastfeeding, menopause, and ageing have a significant impact on sexual well-being, particularly when co-morbid psychiatric illnesses are present. The prevalence of these interactions and their relationship with female sexual dysfunctions are being explored which have consequences in the prevention and treatment of female sexual dysfunctions Objective 1. To assess sexual health knowledge and attitudes regarding sexual practices in women attending Obstetrics and Gynecology Out Patient Department. 2. To assess presence and extent of sexual dysfunctions in these women 3. To evaluate for presence of co-morbid psychiatric conditions Methods Hospital based cross-sectional study with a sample size of 220 women in the category of pregnant, nulliparous and perimenopause/ menopause/ post menopause with age range from 18 to 65 years. Pregnancy carrying high risk and women nearing term were excluded from the study. After a detailed history regarding their socio-economic data, each of them were handed out questionnaires. The SKAQ-II (Sexual knowledge and attitude questionnaire), which was standardized using Indian population assessed their sexual knowledge and attitude, the Female Sexual Functioning Index scale (FSFI) evaluated sexual dysfunction and the presence of psychiatric comorbidities was assessed with the M.I.N.I PLUS scale. Results 93% of the women had an adequate amount of knowledge regarding sexual practice and 83.2% had liberal attitude. Level of sexual knowledge and attitude was positively correlated with presence of sexual dysfunction, with the prevalence of latter being 65.5% with 63% of pregnant women having sexual dysfunction and 77.8% of menopausal women having sexual dysfunction. Rural women had lower levels of sexual knowledge and conservative attitude towards sexual practice, leading to more sexual problems. Around one-fourth of women reported psychiatric morbidities with majority suffering from depression. Conclusions Women with greater sexual knowledge and a liberal mindset towards sexual practices tend to have lower levels of sexual dysfunction. Rural women tended to have lower levels of sexual knowledge and poor attitude towards sexual practice. There was no association found between religious attitudes. Most dysfunctions were reported by the menopausal age group. Sexual issues were more common in the domains of desire, lubrication, orgasm and pain. A positive correlation was noted between sexual dysfunction and kind of housing, leading to lack of intimacy being an important contributing factor. Disclosure No

The impact of sexual dysfunction on quality of life on nurses.

The study was conducted to determine the effect of nurses' sexual life on their quality of life. The study was conducted on 76 nurses working in a hospital in Bursa. Data were collected through Descriptive Data Collection Form, the Female Sexual Function Index (FSFI), and the SF-36 Quality of Life Scale. Mann-Whitney U, Spearman correlation, and Kruskal Wallis test were used to evaluate the data. The average age of the nurses is 38.98±8.05. The average duration of nurses' marriage is 13.95±8.96 years, and 49% of them stated that working life affects their sexual life. Sexual dysfunction was detected in 100% of the nurses. The presence of sexual dysfunction in nurses affects the quality of life. It is important to determine the risk factors in nurses' sexual life patterns to improve the quality of life.

Evaluation of the sexual function of men in Kazakhstan during 2021-2022: A cross-sectional study.

Assessing male sexual function is an important public health issue in every country. In Kazakhstan, there are currently no reliable statistics on male sexual function. The study aimed at the assessment of sexual function in men in Kazakhstan. Men between the ages of 18 and 69 from Astana, Almaty, and Shymkent, three of Kazakhstan's biggest cities, were included in the cross-sectional study in 2021-2022. A standardized and modified Brief Sexual Function Inventory (BSFI) tool was used for participants' interviews. The World Health Organization STEPS questionnaire was employed to gather sociodemographic information, including smoking and alcohol use. Respondents from three cities: n = 283 from Almaty, n = 254 from Astana, and n = 232 from Shymkent were interviewed. All participants' average age was 39.2 ± 13.4. Kazakhs made up 79.5% of the respondents by nationality; 19.1% who answered questions on physical activity verified that they were involved in high-intensity labor. According to the BSFI questionnaire, the respondents from Shymkent had an average total score of 2.82 ± 0.92, (p ≤ 0.05), which was higher than the total scores of respondents from Almaty (2.69 ± 0.87) and Astana (2.69 ± 0.95). A relationship was found between sexual dysfunction and age indicators over 55 years. Participants with overweight had a relationship with sexual dysfunction with an odds ratio (OR): 1.84 (p = 0.01). According to the smoking factor, in study participants with sexual dysfunction, a relationship was also determined,OR: 1.42; 95% confidence interval (CI):0.79-1.97 (p = 0.001). The presence of high-intensity activity (OR: 1.58; 95%CI: 0.04-1.91), and physical inactivity (OR: 1.49; 95%CI: 0.89-1.97) were associated with the presence of sexual dysfunction, p ≤ 0.05. Our research indicates that men over 50 who smoke, are overweight, and are physically inactive are at risk for sexual dysfunction. Early health promotion may be the most effective method to reduce the negative effects of sexual dysfunction on the health and wellbeing of men over 50.

Sexual dysfunction in women suffering from major depressive disorder: A cross-sectional study

AbstractBackground:Compared to a healthy population, sexual dysfunction is higher in major depressive disorder (MDD). Identification and management of sexual dysfunction profoundly impact marital satisfaction, quality of life, and compliance with treatment in patients with depression.Aims and Objectives:The primary objective was to determine the proportion of sexual dysfunction among women suffering from MDD attending the psychiatry department of a tertiary care center. The secondary objectives were (1) to study the correlation between the severity of depression and sexual dysfunction in women with MDD and (2) to study the relationship between sociodemographic and clinical variables with sexual dysfunction.Settings and Design:This was a cross-sectional study carried out among 40 women diagnosed with MDD attending the psychiatry department of our tertiary care institute.Materials and Methods:After taking informed consent, relevant sociodemographic details and clinical variables were recorded using a semi-structured questionnaire. MDD was diagnosed according to the Diagnostic Statistical Manual of Mental Disorders-Fifth Edition, and its severity was assessed using Hamilton rating scale for depression. Sexual dysfunction was measured using the Arizona sexual experience scale.Statistical Analysis:Spearman’s correlation coefficient was used to assess the correlation between the severity of depression and sexual dysfunction. The Chi-square test was used to test the relationship between categorical variables. Analysis of data was done using appropriate statistical software.Results:The proportion of sexual dysfunction among women with MDD was 65%. The most common sexual dysfunction was low sexual desire (57.5%). There was a positive correlation between the severity of depression and the presence of sexual dysfunction, with Spearman’s correlation coefficient (rho = 0.765,P= 0.000). Age, attainment of menopause, history of alcohol and tobacco use in the spouse, and severity of depression were significant with sexual dysfunction using the Chi-square test.Conclusions:The proportion of sexual dysfunction was high among women suffering from MDD. The severity of depression and the presence of sexual dysfunction are positively correlated.

Sexual Dysfunction in Women With Multiple Sclerosis: Expectations Regarding Treatment and Information, and Utility of the SEA-MS-F Questionnaire.

IntroductionSexual dysfunction is a common complaint in female with multiple sclerosis (MS), however this problem is not often considered in the medical and psychological care.AimTo evaluate expectations regarding treatment and information for sexual dysfunction in women with multiple sclerosis using the SEA-MS-F (Sexual Dysfunction Management and Expectations Assessment in Multiple sclerosis - Female) questionnaire, and to gain an understanding of the relationship between their expectations, demographic factors and medical factors known to promote sexual dysfunction.MethodsA prospective epidemiological, descriptive, analytical, multicentre study was carried out over 15 months on adult women suffering from MS. The SEA-MS-F was used to evaluate expectations regarding their sexuality and sexual activity.Main OutcomeMeasure 87 women were included. Mean age was 47 years and the mean time since MS diagnosis was 14 years.Results59.8% reported sexual dysfunction, but only 22.4% of the participants had raised the subject with a professional. With regards to expectations, 68% of the women wanted information about sexual dysfunction and 80% of women with sexual difficulties wanted treatment. High expectations correlated with the presence of sexual dysfunction, a regular sexual partner and with milder ambulatory handicap. There were no correlations between expectations and age, time since MS diagnosis, fatigue or being postmenopausal. The SEA-MS-F questionnaire was perceived as useful by 63.4% of the women and 90% felt that it could help doctors to treat sexual dysfunction.ConclusionTo date, the SEA-MS-F is the only questionnaire validated in women with MS for the evaluation of sexual expectations and in the present study the women felt strongly that it represented a useful way for them to introduce and then discuss the subject of their sexual dysfunction with their doctor.Audrey S-B, Marion R, Béatrice M, et al. Sexual Dysfunction in Women With Multiple Sclerosis: Expectations Regarding Treatment and Information, and Utility of the SEA-MS-F Questionnaire. Sex Med 2022;10:100502.

Dyadic Satisfaction and Shared Affectivity Are Associated with Psycho-Sexual Functioning in Elderly Men and Women

Objectives The quality of sexual life of elderly people represents an understudied topic of sexual medicine and of psycho-sexology. Hence, we aimed to evaluate the association of specific psycho-relational variables, such as intimacy, increased affective gestures towards a partner (AGtP), daily shared activities, and dyadic satisfaction, with the psychosexual wellbeing of elderly people, expressed in terms of sexual satisfaction. Methods: A cohort of elderly people was selected from a sample of a broader study evaluating the role of sexual activity in protecting the emotional wellbeing of a population subjected to quarantine due to the COVID-19 pandemic. Specifically, the presence of sexual dysfunctions, the emotional wellbeing (i.e., absence of anxiety and/or depression), and the quality of the partners’ relationships were studied. For the study’s purpose, the Sexual Health Inventory for Males (SHIM), the Female Sexual Function Index (FSFI), the Orgasmometer and the Orgasmometer-F, the Generalized Anxiety Disorder scale (GAD-7), the Patient Health Questionnaire (PHQ-9), and the Dyadic Adjustment Scale were adopted. Results: A group of 124 elderly subjects (≥60) was selected for the study’s purposes. Among these, 84% were males (120/124), and 16% were females (20/124). All the subjects declared to be in a stable relationship and to be sexually active during the first lockdown period. Gender differences were found for the Dyadic Satisfaction subscale (males: 37.04 ± 6.57; females: 32.85 ± 10.04; p &lt; 0.05) and the Orgasmometer (males: 7.64 ± 1.30; females: 6.60 ± 2.46; p &lt; 0.01). Linear regression analysis showed the association between higher Orgasmometer scores and: (i) the absence of sexual dysfunctions (β = −1.213; SE = 0.271; p &lt; 0.0001), (ii) higher dyadic satisfaction (β = 0.042; SE = 0.019; p &lt; 0.05), and (iii) reduced shared activities with partner (β = −0.463; SE = 0.143; p &lt; 0.01) and increased affective gestures towards partner (DAS measured AGtP) (β = 0.595; SE = 0.065; p &lt; 0.0001). Post hoc analysis of ANCOVA with the Bonferroni correction method showed a significant difference in the Orgasmometer scores between subjects with and without sexual dysfunction (mean difference: 2.102; SE = 0.340; pBonf &lt; 0.001), with healthy subjects reporting higher scores compared to dysfunctional ones. Conclusions: It is reasonable to suppose that, beyond the presence of sexual dysfunctions, the sexual health of elderly people may benefit from the quality of the relationship, and, specifically, from the presence of affective gestures towards the partner and the dyadic satisfaction. To the contrary, the quantity of time spent together, sharing specific activities, may be considered a factor worsening relational and sexual health. These data should be considered during the evaluation of sexual health among elderly people.

Sexual dysfunction in people treated with long‐acting injectable antipsychotics in monotherapy or polypharmacy: a naturalistic study

Sexual dysfunction, psychosis, and antipsychotics are known to be related, but the precise association between them is still unknown. Most evidence about the prevalence of sexual dysfunction in people treated with antipsychotic drugs comes from studies with restrictive samples. That is why our main objective was to determine the prevalence of sexual dysfunction in a real-life sample of outpatients treated with antipsychotics, considering gender. A cross-sectional naturalistic study was developed, including people treated with long-acting injectable antipsychotics, with or without other psychotropic drugs. Participants were interviewed to assess sexual satisfaction through a Likert scale (0 to 10) and the presence of sexual dysfunction (the Psychotropic-Related Sexual Dysfunction Questionnaire, PRSexDQ-SALSEX). The participants also had a blood test to determine prolactin (men and women) and testosterone levels (men only). A total of 131 people participated in the study (90 men and 41 women). Some extent of sexual dysfunction was found in 62.2% of men and 51.2% of women. The most frequent sexual dysfunction symptom for both genders was the loss of libido (45%). Hyperprolactinemia was present in 56% of men and 61% of women. The presence of sexual dysfunction was associated with higher doses of antipsychotics, hyperprolactinemia, and smoking in men and with smoking and hyperprolactinemia in postmenopausal women. This study provides real-life evidence of sexual dysfunction and hyperprolactinemia in persons treated with long-acting injectable antipsychotics segregated by gender. The high rates of sexual dysfunction and hyperprolactinemia detected corroborate the need to consider these aspects in clinical practice.

Statička i dinamska komponenta opstrukcije kod benigne hiperplazije prostate

Introduction / Goal: Benign prostatic hyperplasia (BPH) is the most common benign neoplasm that occures in male population with an incidence of 45 to 90% between 50 and 80 years of age. BPH can cause an increase in output resistance, or an increase in resistance to urine flow, with its static and dynamic components. In clinical practice, the most common pharmacological treatment of lower urinary tract symptoms (LUTS) in patients with BPH is based on monotherapy with alpha-blockers, 5-alpha-reductase inhibitors or combination therapy. The aim of this review is to determine the main therapeutic and side effects of the most common pharmacological therapy and the recommended approaches of the European Association of Urology (EAU) and the American Urological Association (AUA) in the diagnosis of benign prostate obstruction (BPO). Method: Selective literature search with additional examination of EAU and AUA guidelines and meta-analysis. Results: The treatment of patients with BPH is complex. The factors on the basis of which treatment decisions are made are based on the patient's subjective perception of symptoms and quality of life due to LUTS and in relation to the presence of subvesical obstruction. Urodynamic pressureflow studies are the basis for the definition of BPO due to BPH or other etiology. Non-invasive uroflowmetry, determination of residual urine after urination (PVR) and non-invasive ultrasound tests are of great use in the diagnosis of BPO. Treatment with alpha1 receptor inhibitors (alpha-blockers), or 5-alpha-reductase inhibitors may be considered in patients with predominantly urinary dysfunction. Conclusion: Standard pharmacological medical treatment for BPH / LUTS is still based on alphablockers, 5-alpha-reductase inhibitors or a combination thereof. In the future, BPH / LUTS treatment is expected to become individualized, according to the type of symptoms, the presence of sexual dysfunction and the risk of BPH progression.

MP04-06 SEXUAL DYSFUNCTION ON QUALITY OF LIFE AFTER PELVIC FRACTURE

You have accessJournal of UrologyTrauma/Reconstruction/Diversion: External Genitalia Reconstruction and Urotrauma (including transgender surgery) I (MP04)1 Sep 2021MP04-06 SEXUAL DYSFUNCTION ON QUALITY OF LIFE AFTER PELVIC FRACTURE Alice Wang, Monica Vavilala, Frederick Rivara, and Niels Johnsen Alice WangAlice Wang More articles by this author , Monica VavilalaMonica Vavilala More articles by this author , Frederick RivaraFrederick Rivara More articles by this author , and Niels JohnsenNiels Johnsen More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001971.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Pelvic trauma disproportionately affects a younger population and has the potential to cause long-term sexual dysfunction. We hypothesized that the presence of sexual dysfunction after traumatic pelvic fracture negatively impacts health-related quality of life in men. METHODS: 228 patients with traumatic pelvic fractures treated at a level 1 trauma center between 2012 and 2017 completed a survey that evaluated post-injury health-related quality of life and sexual function. Inverse probability weighting was utilized to adjust for survey non-response. Pelvic fracture characteristics were classified based on the Orthopaedic Trauma Association (OTA) classification system. Sexual function was evaluated utilizing the International Index of Erectile Function (IIEF) and health-related quality of life (HrQOL) was evaluated utilizing the EuroQol 5 Dimensions Questionnaire (EQ-5D). Quality-adjusted life years were determined based on calculated EQ-5D utility indices. Multiple regression models were created to evaluate the association between sexual health and HrQOL. RESULTS: After inverse probability weighting and adjustment for potential confounders, a decrease in IIEF was associated with a decline in overall HrQOL as measured by the EQ-5D visual analog scale (ß=0.28, p=0.02). No association was identified between OTA pelvic fracture configuration and risk of post-injury erectile dysfunction (ED) (p=0.99). 53.3% of men reported persistent ED at a median of 42.6 months (IQR 28.0, 63.3) following injury. The presence of ED was independently associated with a decrease in HrQOL (ß=10.92, p<0.001). This difference equates to a loss of 1.6 quality-adjusted life years per 10-years for men with ED following pelvic fracture relative to those without. CONCLUSIONS: Sexual dysfunction is an independent risk factor for decreased HrQOL in pelvic trauma survivors. Further work is needed to create appropriate patient-centered survivorship care pathways that incorporate sexual health evaluation. Source of Funding: 2018 Sexual Medicine Society of North America Pfizer Research Fellowship in Men's Health © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e69-e69 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alice Wang More articles by this author Monica Vavilala More articles by this author Frederick Rivara More articles by this author Niels Johnsen More articles by this author Expand All Advertisement Loading ...

The effect of sexual dysfunction on health-related quality of life in men following traumatic pelvic fractures.

Pelvic trauma disproportionately affects a younger population and has the potential to cause long-term sexual dysfunction. We hypothesized that the presence of sexual dysfunction after traumatic pelvic fracture negatively impacts health-related quality of life (HrQOL) in men. A total of 228 patients with traumatic pelvic fractures treated at a level 1 trauma center between 2012 and 2017 completed a survey that evaluated postinjury HrQOL and sexual function. Inverse probability weighting was used to adjust for survey nonresponse. Pelvic fracture characteristics were classified based on the Orthopedic Trauma Association classification system. Sexual function was evaluated using the International Index of Erectile Function, and HrQOL was evaluated using the EuroQol 5 Dimensions Questionnaire (EQ-5D). Quality-adjusted life years were determined based on calculated EQ-5D utility indices. Multiple regression models were created to evaluate the association between sexual health and HrQOL. After inverse probability weighting and adjustment for potential confounders, a decrease in International Index of Erectile Function was associated with a decline in overall HrQOL as measured by the EQ-5D visual analog scale (β = 0.28, p = 0.02). No association was identified between Orthopedic Trauma Association pelvic fracture configuration and risk of postinjury erectile dysfunction (ED) (p = 0.99). Furthermore, 53.3% of men reported persistent ED at a median of 42.6 months (interquartile range, 28.0-63.3 months) following injury. The presence of ED was independently associated with a decrease in HrQOL (β = 10.92, p < 0.001). This difference equates to a loss of 1.6 quality-adjusted life years per 10 years for men with ED following pelvic fracture relative to those without. Sexual dysfunction is an independent risk factor for decreased HrQOL in pelvic trauma survivors. Further work is needed to create appropriate patient-centered survivorship care pathways that incorporate sexual health evaluation. Prognostic, level IV.

SEXUAL DYSFUNCTION AMONG FEMALE PATIENTS OF RHEUMATOID ARTHRITIS: AN UNDER ADDRESSED PHENOMENON

Objective: To determine the sexual dysfunction among the patients of rheumatoid arthritis and assess the relationship of various factors with presence of sexual dysfunction among the target population.&#x0D; Study Design: Cross sectional study.&#x0D; Place and Duration of Study: Rheumatology department, Pak Emirates Military Hospital Rawalpindi Pakistan, from Aug 2019 to Apr 2020.&#x0D; Methodology: The sample population comprised of 350 married female patients of rheumatoid arthritis between the age of 18 and 45 years, reporting for the routine follow-up at rheumatology department a tertiary care hospital. Sexual function was assessed using the female sexual function index (FSFI). Relationship of age, duration of rheumatoid arthritis, presence of comorbidities and polypharmacy was assessed with the sexual dysfunction among the target population.&#x0D; Results: Mean age of the study participants was 31.15 ± 4.22 years. Out of 350 women suffering from rheumatoid arthritis screened through female sexual function index, 172 (49.1%) had normal sexual function while 178 (50.9%) had sexual dysfunction. After applying the chi-square test, we found that polypharmacy and long duration of illness had significant association with the sexual dysfunction.&#x0D; Conclusion: High reporting of sexual dysfunction among the women suffering from rheumatoid arthritis indicates that this has been a neglected phenomenon by the physicians and researchers and may be added in routine screening. Women with long duration of illness and those managed with more than one drugs should be focused more while screening for sexual problems.

Sexual dysfunctions and short-term glucose variability in young men with type 1 diabetes

PurposeErectile dysfunction (ED) and premature ejaculation (PE) are common sexual disorders in people with diabetes. Glucose variability (GV) has been recognized as a predictor of microvascular complications. The aim of this study was to investigate the relationship between glucose variability and sexual dysfunctions in young men with type 1 diabetes.MethodsOne hundred and twelve patients with type 1 diabetes, aged 18–30 years, were enrolled. Patients were divided into two groups according to glucose variability [group 1 (high GV with coefficient of variation ≥ 36%)] and group 2 (low GV with coefficient of variation < 36%)). The presence of sexual dysfunctions was investigated with validated questionnaires.ResultsED and PE prevalence rates in group 1 were 26% and 13%, respectively. Similarly, in group 2, the prevalence of ED was 24%, and the prevalence of PE was 13%. In both groups, no significant associations between sexual dysfunctions and parameters of glucose variability were found. Multiple regression analysis identified age and depression as independent predictors of ED and PE.ConclusionYoung male patients affected by type 1 diabetes with high or low glucose variability show a similar prevalence of sexual dysfunctions. ED is the most common sexual dysfunction in diabetic men. Age and depression were the only independent predictive factors for sexual dysfunctions in this population.

"When Love Does not bear a Fruit": Patterns and Prevalence of Sexual Difficulties in Infertile Men and Women as Predictors of Emotional Distress.

Background:Self-identity, sexuality, and subfertility have multidirectional effects on each other. Subfertility is known to alter sexual esteem, threaten identity, body image, sexual attractivness, coital pleasure, and sexual satisfaction.Objective:This study aimed to evaluate sexual difficulties as predictors of infertility-specific stress in patients undergoing fertility treatments and to assess the profile of sexual dysfunctions in participants.Study Setting and Design:This cross-sectional study was conducted in a tertiary hospital setup of a medical college.Methods:Three hundred married men and women diagnosed with infertility participated. The psychological evaluation test, international classification of diseases (10th, CDDG), female sexual functioning index, and international index of erectile functioning were used as measures.Statistical Analysis:Data were analyzed using SPSS (version 15, Chicago, USA). Chi-square test was used for univariate analysis between stress and presence of sexual dysfunctions in men and women. Medians, quartile, and cutoff scores were used to profile the sexual issues in participants.Results:Prevalence of sexual dysfunctions since marriage was higher in women (75%) than men (60%). Ninety-two percent of women and 86% of men experienced emergence of sexual difficulties after the couple started treatments.Conclusions:Sexual dysfunctions appear to be a consistent psychosocial concern for those awaiting conception. These appear to worsen during the treatments. Our findings suggest the need to sensitively approach and explore sexual anamnesis with the couple before recourse to medically assisted reproductive treatments. Psychological interventions for sexual issues in distressed patients before, during, and after treatments such as controlled ovarian hyperstimulation, intrauterine insemination, in vitro fertilization, and intracytoplasmic sperm injection are most needed.

PHYSIOTHERAPEUTIC ACTIVITY IN THE TREATMENT OF PENETRAL GENE PAIN / PENETRATION WITH A FOCUS ON THE MANUAL THERAPY APPROACH IN WOMEN AT MENACME

Genital-pelvic pain / penetration disorder (DGPP) includes vaginismus, dyspareunia and vulvodynia, where the following symptoms are present: Presence of fear or anxiety related to vulvovaginal or pelvic pain in anticipation, during or as a result of vaginal penetration, in addition to the presence of tension or hardening of the pelvic floor muscles during the attempt of vaginal penetration. Adequate sexual function is considered an important factor for quality of life, being recognized by WHO (World Health Organization) regarding the presence of sexual dysfunction as a public health problem, recommending its investigation for causing important changes in quality of life and in the relationship with your partner. It is identified that the role of the physiotherapist becomes relevant in the process of identification and rehabilitation of genito-pelvic pain, justifying the importance of studies on this topic. In order to analyze the role of the physiotherapist in the treatment of pelvic genital pain / penetration with a focus on the approach of manual therapy in women at menacme, a narrative review of the literature was carried out, where 17 articles were used as a basis for research and data collection. During the analysis of the articles, it was defined that DSFs tend to appear in the female fertile phase, causing pain and discomfort. In the reviews covered in this study, it was analyzed that DGPP is a complex syndrome in which the sensation and intensity of pain are felt in different places. With this the diagnosis becomes difficult taking into account the shame and / or blocking of the woman in reporting a sexual complaint. Through a physical therapy assessment, in order to check the tone and function of the pelvic floor muscles, the existence and location of tender points, as well as the understanding of voluntary contractions and rests of these muscles, a therapeutic planning with the use of interventions is outlined. specific measures in self-relaxation and anxiety control techniques, improving body awareness. It is concluded that there is effectiveness in exploring self-knowledge to improve the quality of life of women who suffer from this problem, providing positive results in a short period, thus contributing to the improvement of the sexual function of women with DSFs (Female Sexual Dysfunctions).

Disfunção sexual no período gestacional e sua relação com variáveis obstétricas

Objetivo: analisar a relação entre o Índice de Função Sexual Feminina (IFSF) e variáveis obstétricas relacionadas ao período gestacional. Métodos: Estudo observacional, transversal, unicêntrico, com coleta de dados primários realizada com 60 gestantes. Os instrumentos utilizados foram questionário sociodemográfico e IFSF. As gestantes foram agrupadas em dois grupos de acordo com o escore de função sexual feminina (normal ou com disfunção) conforme ponto de corte pré-estabelecido. Foram analisadas a idade materna, idade gestacional, índice de massa corporal e paridade, assim como as médias de cada domínio do IFSF. Resultados: A prevalência de disfunção sexual foi de 40%. No grupo com disfunção sexual, houve maiores médias de idade materna (22,9 ± 3,3 vs 25,5 ± 4,3 anos; p = 0,011), de idade gestacional (25 ± 7,2 vs 29,7 ± 7,8 semanas; p = 0,017) e índice de massa corpórea (26 ± 3,5 vs 29,9 ± 3,6 Kg/m2; p &lt; 0,001). Foi observada diferença estatisticamente significante para todos os domínios do IFSF entre os grupos com e sem disfunção. Conclusão: Houve relação de fatores obstétricos com a presença da disfunção sexual. A alta prevalência de disfunção sexual nesse período bem como a identificação dos fatores relacionados chama atenção para a necessidade de políticas púbicas de atenção voltadas para a saúde sexual feminina, enfatizando o período gestacional, a fim de garantir uma maior e melhor qualidade de vida para esse público. Descritores: Disfunção sexual fisiológica; Gravidez; Grávidas.