Presence Of Posttraumatic Stress Disorder Research Articles

Современные методы психологической работы с посттравматическим стрессовым расстройством у военнослужащих

<p>The article describes the importance of psychological work with military personnel, primarily in the presence of post-traumatic stress disorder (PTSD) associated with participation in hostilities. A brief description of the causes and symptoms of PTSD is given. The main directions of psychological work with military personnel participating in hostilities are described. The topic of the qualifications of psychologists who come into contact with this complex issue in their professional activities is touched upon. The possibilities of various areas of psychological work with PTSD are discussed, including art therapy, cognitive behavioral therapy, aromatherapy, and others. Psychological work with PTSD in interaction with military personnel is described in the following main areas: directly during combat operations, in hospitals, and in rehabilitation centers. Psychodiagnostic techniques used in the detection of PTSD and the current condition of a servicemember are mentioned. Studies confirming the effectiveness of various methods and techniques of working with PTSD are described.</p>

Post-traumatic Stress Disorder in Women in Post-Natal Period

Objective: To assess and evaluate the presence of post-traumatic stress disorder and its associated factors affecting the women in post-natal period. Material and Methods: Data was collected through a cross-sectional survey from February 2023-July, 2023 at the Department of obstetrics and gynaecology, Ghurki Trust Teaching Hospital Lahore and 101 women fulfilling various diagnostic criteria for post-traumatic stress disorder in post-natal period were included in the study. PTSD symptoms were assessed using the “City Birth Trauma Scale” (CBTS) questionnaire including various stratification of events. SPSS 27.0 software was used for data analysis. Results: The results showed the possible outcome of several factors such as mode of delivery, family system, support and terms with partner or any previous psychiatric illness/PTSD or PTSD following child birth. Women with partner support had a significantly lower incidence of distress & impairment symptoms (33.3%) compared to those without support (81.8%) as p<.05. Conclusion: Our study depicted statistically significant link between PTSD criteria for distress and impairment and partner support and good terms with partner. Given that, partner support ought to be more than what is provided to lower the incidence of PTSD in women following child birth.

Pathway from Childhood Maltreatment to Perceived Parental Competence and Intimate Partner Violence Among Expecting Fathers: The Role of PTSD Symptoms

ABSTRACT Men who have a history of childhood maltreatment may be at risk of experiencing significant challenges during the transition to parenthood, which might be explained by the presence of post-traumatic stress disorder (PTSD) symptoms. Using a nonclinical community sample of 230 expecting fathers, the aims of the current study were as follows (1) to investigate, during the prenatal period, associations between childhood maltreatment and perceived parental competence as well as between childhood maltreatment and intimate partner violence, and (2) to evaluate whether PTSD symptoms contributed to explaining these associations. A structural equation model showed that the severity of childhood maltreatment predicted more severe PTSD symptoms, which in turn predicted higher levels of intimate partner violence as well as a lower perceived parental competence. No direct associations between childhood maltreatment and both perceived parental competence and intimate partner violence were observed. Implications for interventions and future research are discussed.

Risk factors for posttraumatic stress disorder in trauma patients from bullfighting-related events in Spain

BackgroundUnintentional Trauma injuries are one of the leading causes of posttraumatic stress disorder development. However, screening for this condition is not typically included in routine medical care. Research on posttraumatic stress disorder after unintentional injuries sustained during entertainment activities involving risk, has been scarce. This study aimed to analyze the proportion of posttraumatic stress disorder and its risk factors in patients with trauma injuries sustained during bullfighting-related events in Spain. MethodsTwo hundred and seventy-four patients were evaluated to determine the presence of posttraumatic stress disorder at least one month after the injury. Data about sociodemographic variables, injury circumstances, characteristics of the injury, and treatments were collected by the surgery team on-site or collected during the follow-up assessment. Diagnosis of posttraumatic stress disorder was made by a trained clinician using a structured clinical interview based on DSM criteria. ResultsThe estimated proportion of was 25.18 % (95 % CI: 20.18 %, 30.18 %). Residing in areas with a bullfighting tradition, female gender, referral to a medical center, hospitalization, events involving fighting bulls, and having been injured by the crowd were significant predictors. LimitationsThe short-term follow-up and the inability to evaluate some predictors of interest, including the body site of the injury, the presence of disfigurement, and comorbid anxiety and depression, were noted. ConclusionPosttraumatic stress disorder could have a high prevalence in individuals injured in these types of events, especially in women, those who are not familiar with the situation, and those who require medical attention. These results highlight the need for routine screening for posttraumatic stress disorder in individuals with trauma injuries for early symptom management.

Disentangling the effects of PTSD from Gulf War Illness in male veterans via a systems-wide analysis of immune cell, cytokine, and symptom measures

BackgroundOne-third of veterans returning from the 1990–1991 Gulf War reported a myriad of symptoms including cognitive dysfunction, skin rashes, musculoskeletal discomfort, and fatigue. This symptom cluster is now referred to as Gulf War Illness (GWI). As the underlying mechanisms of GWI have yet to be fully elucidated, diagnosis and treatment are based on symptomatic presentation. One confounding factor tied to the illness is the high presence of post-traumatic stress disorder (PTSD). Previous research efforts have demonstrated that both GWI and PTSD are associated with immunological dysfunction. As such, this research endeavor aimed to provide insight into the complex relationship between GWI symptoms, cytokine presence, and immune cell populations to pinpoint the impact of PTSD on these measures in GWI.MethodsSymptom measures were gathered through the Multidimensional fatigue inventory (MFI) and 36-item short form health survey (SF-36) scales and biological measures were obtained through cytokine & cytometry analysis. Subgrouping was conducted using Davidson Trauma Scale scores and the Structured Clinical Interview for Diagnostic and statistical manual of mental disorders (DSM)-5, into GWI with high probability of PTSD symptoms (GWIH) and GWI with low probability of PTSD symptoms (GWIL). Data was analyzed using Analysis of variance (ANOVA) statistical analysis along with correlation graph analysis. We mapped correlations between immune cells and cytokine signaling measures, hormones and GWI symptom measures to identify patterns in regulation between the GWIH, GWIL, and healthy control groups.ResultsGWI with comorbid PTSD symptoms resulted in poorer health outcomes compared with both Healthy control (HC) and the GWIL subgroup. Significant differences were found in basophil levels of GWI compared with HC at peak exercise regardless of PTSD symptom comorbidity (ANOVA F = 4.7, P = 0.01,) indicating its potential usage as a biomarker for general GWI from control. While the unique identification of GWI with PTSD symptoms was less clear, the GWIL subgroup was found to be delineated from both GWIH and HC on measures of IL-15 across an exercise challenge (ANOVA F > 3.75, P < 0.03). Additional differences in natural killer (NK) cell numbers and function highlight IL-15 as a potential biomarker of GWI in the absence of PTSD symptoms.ConclusionWe conclude that disentangling GWI and PTSD by defining trauma-based subgroups may aid in the identification of unique GWI biosignatures that can help to improve diagnosis and target treatment of GWI more effectively.

Post-traumatic stress disorder due to COVID-19 pandemic on healthcare workers in various hospitals in Da Nang, 2021

The COVID-19 pandemic posed a significant challenge to healthcare workers (HCWs), resulting in adverse effects on their mental health. This study aims to identify post-traumatic stress disorder (PTSD) due to the COVID-19 pandemic and related factors among healthcare workers in Da Nang, 2021. A cross-sectional study was conducted among 230 healthcare workers through a purposive sampling. The Impact of Event Scale-Revised (IES-R) was used to measure post-traumatic stress disorder. The prevalence of post-traumatic stress disorder among healthcare workers in this study was 33.04% (95% CI: 27.00 – 39.53). The levels of post-traumatic stress disorder were categorized into four groups: normal (57.83%), clinically concerning (9.13%), post-traumatic stress disorder (6.52%), and extreme symptoms (26.52%). Gender, age group, living status, workplace and risk of exposure to COVID-19 were significantly associated at p-value &lt; 0.05. This study revealed a significant presence of post-traumatic stress disorder among the healthcare workers in the sample. Additional support should be provided to healthcare workers in order to address and mitigate the impact of PTSD due to COVID-19.

Long-term socio-psychological disaster impact after 8 years: Relationships between the persistent impact of the Fukushima disaster and individuals’ media and community connectedness

Residents of Fukushima Prefecture continue to face trauma after Japan's 2011 nuclear disaster. While there remains a substantial presence of posttraumatic stress disorder (PTSD) in the prefecture, and the majority of literature tends to view PTSD as an individual psychological disease that can be ameliorated; there is little understanding about how individuals experiencing PTSD influence their communities over time. The present research employs Barton's collective stress theory and Ball-Rokeach et al.'s communication infrastructure theory to examine multilevel effects of individual-level trauma and offers a new term, long-term socio-psychological disaster impact (LTSDI). LTSDI modifies pre-existing notions of persistent PTSD to a neutral understanding of experiences of symptomology and various levels of individuals’ impacts on their communities. Survey research conducted in Fukushima eight years after the disaster and analyses employing structural equation modeling found individuals experiencing LTSDI can positively contribute to their communities through community connectedness, a measure of interpersonal storytelling, collective efficacy, and civic participation. Implications of the study are discussed.

Mental health and post-traumatic stress disorder in firefighters: an integrated analysis from an action research study.

The presence of post-traumatic stress disorder (PTSD) symptomatology in firefighters is an ever-pressing issue that requires close attention for adequate interventions. The present study investigated PTSD and global psychopathology prevalence in a sample of highly risk-exposed Portuguese firefighters, collected after the widespread deadly wildfires in 2017 that ravaged the country. Following an action research approach, the aim of this study was to depict this sample and examine the impact of cumulative adverse experiences on their mental health, which is a phenomenon worth attention. From an initial sample of 283 firefighters who manifested interest in participating, a total of 139 firefighters from the Coimbra District, of whom 130 unequivocally experienced a potentially traumatic/adverse event as a firefighter, completed BSI (to obtain indicators on psychopathology), QEPAT (an inventory of adverse events possibly experienced as a firefighter), and PCL-5 (a measure of PTSD symptomatology) through an online survey during the year 2018 by the Regional Medical Organization, as proposed and supervised by the local Centre for Prevention and Treatment of Psychological Trauma (CPTTP). We found a global prevalence of 8.6% of possible PTSD and 14.4% of possible psychopathology (n = 139). When considering only firefighters who unequivocally reported a potentially traumatic/adverse event as a firefighter (n = 130), 9.2% present possible PTSD, and 13.8% present possible global psychopathology. This sample experienced a mean of 28 adverse events during firefighting work. Linear regressions (n = 118) demonstrated that the perceived severity of the most traumatic event reported and the experience of more adverse events were both related to an increase in PTSD symptomatology. Global psychopathology was associated with PCL-5 scores, with an emphasis on paranoid ideation, hostility, depression, anxiety, and phobic anxiety. The severe wildfires of 2017 did not impact PTSD scores in this sample (collected the year after), suggesting that cumulative adverse events are more important than particular episodes. However, the number of reported events was related to PTSD scores. These results can be used to develop interventions that target all firefighters by addressing risk and protective factors. This action research study motivated specialized aid for firefighters involved in this study.

Post-Traumatic Stress Disorder in Patients with Alopecia Areata: A Survey Study in the USA

Introduction: Alopecia areata (AA) is an autoimmune condition that results in nonscarring hair loss. AA is comorbid with mental health disorders including anxiety and depression. This study aimed to evaluate the presence of post-traumatic stress disorder (PTSD) in relation to hair loss in patients with AA. Methods: A cross-sectional national survey was distributed using the National Alopecia Areata Foundation’s (NAAF) email list. This study was approved by the Mass General Brigham Institutional Review Board. Participants were asked to complete the PTSD Checklist for the DSM-5 (PCL-5), a validated screening tool for PTSD in the context of their AA. Results: Of the 1,449 completed surveys (completion rate 79.6%), most respondents were female (83.8%) and white (76.6%) with an average age of 50.6 ± 15.6 years. Respondents had AA for an average of 17.7 ± 15.8 years, with 91.4% experiencing current active hair loss. A total of 33.9% of respondents screened positively for PTSD, with an average score of 48.8 ± 12.3 on the PCL-5 in participants who screened positively. Participants with alopecia totalis have the highest average PCL-5 score of 30.1 ± 19.2, followed by participants with alopecia universalis with an average score of 26.0 ± 19.9, and lastly patchy AA with an average score of 24.5 ± 18.3 (p = 0.003). Feelings of intrusion and avoidance were the predominant reported symptoms. Total PTSD scores were significantly higher in respondents who were younger and identified as Black or African American and Hispanic when compared to white and non-Hispanic respondents, respectively. Conclusion: These findings identify that one in 3 patients with AA in this cohort meet the screening criteria for PTSD specifically relating to their hair loss experience. These results further highlight the mental health comorbidities associated with AA and emphasize that these symptoms may persist even after hair regrowth. Limitations include the nonrandomized NAAF population with most participants being white females. Future studies should confirm these findings in other patient populations. Finally, respondent’s baseline mental health was not assessed; therefore, a causal relationship between AA and PTSD cannot be deduced.

외상 후 스트레스 장애 잔단 유무에 따른 고령의 재향 군인의 뇌백질 고신호 차이

Objective: Exposure to stressful events is associated with the progression of white matter hyperintensity (WMH). The purpose of this study was to determine the difference in WMH depending on the presence of Post-traumatic stress disorder (PTSD).&#x0D; Methods: The patients who underwent brain magnetic resonance imaging and clinician-administered PTSD scale (CAPS) at the Veteran Health Service Medical Center were reviewed retrospectively. WMH were evaluated using the Fazekas scale. The patients with PTSD (n=51; age 66.25±10.43 years) were compared with patients exposed to trauma without PTSD (n=67; age 69.45±10.44 years).&#x0D; Results: The scores of Beck Depression Scale, Beck Anxiety scale, and CAPS were significantly higher in the PTSD group. The PTSD group showed a significant difference on the Fazekas scale compared to the trauma-exposed group without PTSD (periventricular white matter, p=0.001; deep white matter, p=0.008). After adjusting for age, smoking and comorbidity, WMH was higher in the PTSD group than in the trauma exposed group (periventricular white matter, p&lt;0.001; deep white matter, p=0.006).&#x0D; Conclusion: The results suggests that there may be an association between PTSD and WMH as well as stressful events

Trauma Experiences Are Common in Anorexia Nervosa and Related to Eating Disorder Pathology but Do Not Influence Weight-Gain during the Start of Treatment.

The main characteristics of Anorexia Nervosa (AN) in adults are restriction of energy intake relative to requirements leading to significant weight loss, disturbed body image, and intense fear of becoming fat. Traumatic experiences (TE) have been reported as common, although less is known about the relationship with other symptoms in severe AN. We investigated the presence of TE, PTSD, and the relation between TE, eating disorder (ED) symptoms, and other symptoms in moderate to severe AN (n = 97) at admission to inpatient weight-restoration treatment. All patients were enrolled in the Prospective Longitudinal all-comer inclusion study on Eating Disorders (PROLED). TE were assessed using the Post-traumatic stress disorder checklist, Civilian version (PCL-C), and ED symptoms using the Eating Disorder Examination Questionnaire (EDE-Q); depressive symptoms were assessed using the Major Depression Inventory (MDI), and the presence of Post-traumatic Stress Disorder (PTSD) was diagnosed according to ICD-10 criteria. The mean score on PCL-C was high (mean 44.6 SD 14.7), with 51% having a PCL-C score at or above 44 (n = 49, suggested cut-off for PTSD), although only one individual was clinically diagnosed with PTSD. There was a positive correlation between baseline scores of PCL-C and EDE-Q-global score (r = 0.43; p < 0.01) as well as of PCL-C and all EDE-Q subscores. None of the included patients were admitted for treatment of TE/PTSD during the first 8 weeks of treatment. In a group of patients with moderate to severe AN, TE were common, and scores were high, although only one had a diagnosis of PTSD. TE were related to ED symptoms at baseline, but this association diminished during the weight restoration treatment.

Association between traumatic life events and vaccine hesitancy: A cross-sectional Australian study

ObjectivesWe sought to identify associations between the experience of traumatic life events and vaccination intention to inform whether trauma-affected individuals require targeted interventions when addressing vaccine hesitancy. Study designWe conducted an online cross-sectional survey to identify whether direct or indirect exposure to various traumatic life events and the presence of post-traumatic stress disorder (PTSD) symptoms are associated with willingness to receive a COVID-19 vaccine in an Australian sample. MethodsA national online questionnaire was administered to a representative sample of 1050 Australian adults in September 2021. ResultsLower willingness to receive a COVID-19 vaccine was associated with direct experience of a fire or explosion (adjusted odds ratio [aOR]: 0.42; 95% confidence interval [CI]: 0.23–0.78; P = 0.006), direct experience of severe human suffering (aOR:0.39; 95% CI: 0.21–0.71; P = 0.002) and screening positive for PTSD symptoms (aOR:0.52; 95% CI: 0.33–0.82; P = 0.005). Conversely, higher willingness to receive a COVID-19 vaccine was associated with indirect exposure to severe human suffering (aOR: 2.0; 95% CI: 1.21–3.22; P = 0.007). ConclusionsOur findings suggest that the experience of traumatic events and the presence of PTSD symptoms can contribute to vaccination decisions. Our work adds to the growing recognition of the need to effectively mediate the influence of traumatic experiences on encounters within the medical setting and supports the importance of addressing the needs of trauma-affected individuals in their vaccination experiences.

Analysis of Psychological Symptoms Following Disclosure of Amyloid–Positron Emission Tomography Imaging Results to Adults With Subjective Cognitive Decline

Individuals who are amyloid-positive with subjective cognitive decline and clinical features increasing the likelihood of preclinical Alzheimer disease (SCD+) are at higher risk of developing dementia. Some individuals with SCD+ undergo amyloid-positron emission tomography (PET) as part of research studies and frequently wish to know their amyloid status; however, the disclosure of a positive amyloid-PET result might have psychological risks. To assess the psychological outcomes of the amyloid-PET result disclosure in individuals with SCD+ and explore which variables are associated with a safer disclosure in individuals who are amyloid positive. This prospective, multicenter study was conducted as part of The Amyloid Imaging to Prevent Alzheimer Disease Diagnostic and Patient Management Study (AMYPAD-DPMS) (recruitment period: from April 2018 to October 2020). The setting was 5 European memory clinics, and participants included patients with SCD+ who underwent amyloid-PET. Statistical analysis was performed from July to October 2022. Disclosure of amyloid-PET result. Psychological outcomes were defined as (1) disclosure related distress, assessed using the Impact of Event Scale-Revised (IES-R; scores of at least 33 indicate probable presence of posttraumatic stress disorder [PTSD]); and (2) anxiety and depression, assessed using the Hospital Anxiety and Depression scale (HADS; scores of at least 15 indicate probable presence of severe mood disorder symptoms). After disclosure, 27 patients with amyloid-positive SCD+ (median [IQR] age, 70 [66-74] years; gender: 14 men [52%]; median [IQR] education: 15 [13 to 17] years, median [IQR] Mini-Mental State Examination [MMSE] score, 29 [28 to 30]) had higher median (IQR) IES-R total score (10 [2 to 14] vs 0 [0 to 2]; P < .001), IES-R avoidance (0.00 [0.00 to 0.69] vs 0.00 [0.00 to 0.00]; P < .001), IES-R intrusions (0.50 [0.13 to 0.75] vs 0.00 [0.00 to 0.25]; P < .001), and IES-R hyperarousal (0.33 [0.00 to 0.67] vs 0.00 [0.00 to 0.00]; P < .001) scores than the 78 patients who were amyloid-negative (median [IQR], age, 67 [64 to 74] years, 45 men [58%], median [IQR] education: 15 [12 to 17] years, median [IQR] MMSE score: 29 [28 to 30]). There were no observed differences between amyloid-positive and amyloid-negative patients in the median (IQR) HADS Anxiety (-1.0 [-3.0 to 1.8] vs -2.0 [-4.8 to 1.0]; P = .06) and Depression (-1.0 [-2.0 to 0.0] vs -1.0 [-3.0 to 0.0]; P = .46) deltas (score after disclosure - scores at baseline). In patients with amyloid-positive SCD+, despite the small sample size, higher education was associated with lower disclosure-related distress (ρ = -0.43; P = .02) whereas the presence of study partner was associated with higher disclosure-related distress (W = 7.5; P = .03). No participants with amyloid-positive SCD+ showed probable presence of PTSD or severe anxiety or depression symptoms at follow-up. The disclosure of a positive amyloid-PET result to patients with SCD+ was associated with a bigger psychological change, yet such change did not reach the threshold for clinical concern.

Provision of Psychological Support to a 31-Year-Old Man with SARS-CoV2-Induced Pneumonia during and after Hospitalization: A Clinical Case Report

A 31-year-old man hospitalized during the first wave of the pandemic in 2020 suffering from severe psychological distress, requested psychological assistance as his condition progressively worsened, eventually requiring intubation. After being referred to the clinical psychology service by a ward physician, the patient was assisted remotely for two months for a total of 22 sessions during hospitalization and after discharge. A psychometric evaluation was carried out when the patient was close to discharge and longitudinally, for a total of four times, for depression (Patient Health Questionnaire-9 (PHQ-9)), anxiety (Generalized Anxiety Disorder Scale-7 (GAD-7)), post-traumatic stress disorder (Impact of Event Scale-Revised (IES-R)) and insomnia (Insomnia Severity Index (ISI)). Support was provided remotely, mainly through audio and video calls, and text chats were also utilized when possible and as required. The initial psychometric evaluation indicated moderate depression, severe anxiety, the presence of post-traumatic stress disorder and sleep problems. Psychological distress decreased until reaching a situation of no distress in the final evaluation. Psychological interventions from which the patient benefitted were stress reduction and breathing techniques, empathic support, elaboration of the possibility of grief and cognitive restructuring regarding fears relative to his condition. Psychological support provided remotely and the monitoring of psychological status after discharge are highly advisable in pandemic emergency situations. The CARE checklist of information to include when writing a case report was utilized in the writeup of this case report.

Patient Mental Health and Well-being: Its Impact on Orthopaedic Trauma Outcomes.

A patient's mental health can have a significant impact on their orthopaedic trauma outcome. It is important for orthopaedic surgeons to identify patients at risk for a poor outcome based on their mental health, to include the presence of post-traumatic stress disorder, depression, and anxiety, among others. Although some behaviors such as catastrophizing have been associated with worse outcomes, others, such as possessing greater self-efficacy have been associated with improved outcomes. Because of the high prevalence of mental health conditions that can have a detrimental effect on outcome, screening should be routinely conducted and at-risk patients referred to appropriate resources in an effort to optimize outcomes.

Posttraumatic Stress Disorder, Anxiety, and Depression Symptoms After Potentially Traumatic Events: Latent Classes and Cognitive Correlates.

People exposed to potentially traumatic events (PTEs) may develop distinct symptom patterns, which may require different therapeutic approaches. We aimed to identify classes of people exposed to PTEs based on the presence of posttraumatic stress disorder (PTSD) clusters, anxiety, and depression and to explore which cognitive factors (rumination, worry, and negative cognitions) are associated with class membership. Latent class analyses were conducted to identify subgroups of 258 PTE-exposed Spanish adults. A three-class solution emerged: a resilient class with low odds of all symptoms ( n = 188); a partial PTSD class, characterized by partial PTSD clusters, moderate anxiety, and low depression ( n = 36); and a high symptom class, characterized by high PTSD, moderate anxiety, and low depression ( n = 34). These classes related meaningfully to rumination, worry, and negative cognitions. Distinct symptom patterns of PTSD clusters, anxiety, and depression can be distinguished in people exposed to PTEs and relate to cognitive risk factors of psychopathology.

Delphi study to define core clinical outcomes for inclusion in a complex regional pain syndrome international research registry and data bank.

Complex regional pain syndrome (CRPS) clinical trials have historically captured a diverse range of outcomes. A minimum set of CRPS patient-reported outcomes has been agreed for inclusion in a future CRPS international clinical research registry and data bank. This study aimed to identify a complementary set of core clinical outcomes. Clinicians and researchers from the international CRPS community informed the content of a 2-round electronic Delphi study. Participation was invited from members of the International Association for the Study of Pain CRPS Special Interest Group and the International Research Consortium for CRPS. In round 1, participants rated the relevance of 59 clinical outcomes in relation to the question "What is the clinical presentation and course of CRPS, and what factors influence it?" (1 = not relevant and 9 = highly relevant). In round 2, participants rerated each outcome in the light of the round 1 median scores. The criterion for consensus was median score ≥7, agreed by 75% of respondents. The core study team considered the feasibility of data collection of each identified outcome in agreeing final selections. Sixty respondents completed both survey rounds, with responses broadly consistent across professions. Nine outcomes met the consensus criterion. Final outcomes recommended for inclusion in the core clinical set were record of medications, presence of posttraumatic stress disorder, extent of allodynia, and skin temperature difference between limbs. Study findings provide robust recommendations for core clinical outcome data fields in the future CPRS international clinical research registry. Alongside patient-reported outcomes, these data will enable a better understanding of CRPS.

Use of an Online Platform to Evaluate the Impact of Social Distancing Measures on Psycho-Physical Well-Being in the COVID-19 Era.

Background: The SARS-CoV-2 pandemic (Severe Acute Respiratory Syndrome Coronavirus 2) and the worldwide health crisis have significantly changed both people’s habits and lifestyles. Most of the studies found in the literature were carried out on specific professional categories in the socio-health sector, taking into consideration psychological disorders in relation to work. The purpose of this study was to analyze the psychological impact on a portion of the normal population subjected to lockdown. Methods: A questionnaire was distributed in the period between 23 March 2020 and 18 May 2020 (during Italian lockdown) using an online platform. The scales GAD-7, IES-r, PHQ-9 and MANSA were used to investigate the level of anxiety, the presence of post-traumatic stress disorder, the severity of depression and the perceived quality of life, respectively. Results: Four hundred and eight Italian subjects responded. Females and younger people were more affected by anxiety and depression. Post-traumatic stress disorder affected about 40% of the population sample, significantly young people and women, thus attesting to an important psychopathological response. About one-fifth of the sample population recorded an unsatisfactory quality of life. Conclusions: The results highlight the need to set up preventive interventions (primary and secondary), trying to focus on the most fragile group of subjects from a psychosocial point of view, in order to obtain a significant reduction in psychophysical damage in terms of relapses and outcomes.

Psychological impact of pediatric cancer : a cross-sectional study among thirty parents

IntroductionThe diagnosis of pediatric cancer is a traumatic event that is considered to be one of the most adverse situations the child and his family can experience. The psychological impact of this diagnosis on the parents has triggered a great scientific attention in these recent years.ObjectivesEstimate the prevalence of depression and post-traumatic stress among parents of children with cancer.MethodsOur study was cross-sectional over a period of 1 month in the medical carcinology department at the Salah Azaeiz Institute. We used the Beck Depression Scale II and the Post Traumatic Stress Disorder Cheklist-Civilian assessements.ResultsThirty parents participated in our study. Most of whom were mothers (73%). The educational level was primary in 63% of cases and socio-economic level was average in 60% of parents. 40% of parents were assessed within six months after diagnosis. Prevalence of depressive disorder and post-traumatic stress disorder were 73% and 57% respectively. The low educational level was correlated to the presence of these two disorders. Similarly, the low educational level was correlated to the presence of depressive disorders (p=0.008). The number of children in the family was also associated to the presence of post-traumatic stress disorder (p=0.029).ConclusionsThe prevalence of depressive and post-traumatic stress disorders was high among parents of children diagnosed with cancer. The low socio-economic and educational level and the large number of children in the family are risk factors for psychological distress. Psychosocial support should be offered to parents of children with cancer to optimize the management of this disease.DisclosureNo significant relationships.

Experience and impact of the COVID-19 pandemic in patients with systemic lupus erythematosus in France

IntroductionThe SARS-CoV-2 pandemic and its successive lockdowns are considered as anxious periods, especially for immunocompromised patients such as those with systemic lupus erythematosus (SLE). In addition to the personal and professional difficulties linked to the pandemic, care supply or access to treatment (such as hydroxychloroquine, HCQ) may have affected these patients. The aim of this work was to assess the experience and the impact of these difficulties endured by patients with SLE during the COVID-19 pandemic.Patients et méthodesAnonymous survey conducted in France and DOM-TOM departments via paper or online forms (SurveyLegend® platform). Patients with SLE were recruited with the support of the French Association of Lupus (AFL +) as well as through their treating specialist. Socio-demographic data were collected, and the impact of lockdowns was assessed by validated questionnaires aimed at assessing perceived stress (Perceived Stress scale 10), anxiety and depression (Hospital Anxiety and Depression Scale, HADS) and the occurrence post-traumatic stress disorder (PTSD Checklist for DSM-5, PCL-5). Participants consented to the use of their data and the survey methodology was validated by an independent ethics committee (CE-2020-151).RésultatsFive hundred thirty-six questionnaires were collected from SLE patients between November 2020 and April 2021. The median age was 50 years [IQR: 39–60] and 91.9% of patients were female. Their disease had progressed for a median of 17 [9–25] years, 77% were treated with HCQ, 50% with corticosteroids and 33% with immunosuppressive treatments. During the pandemic, 85 patients ceased their professional activity (technical unemployment n = 55, dismissal n = 30). Financial difficulties were reported by 76 patients (15.9%), with a significant predominance among those who interrupted their professional activity36.9% vs. 9.3%, p < 0.0001). Of the patients treated with HCQ, 23.9% (92/385) had difficulty accessing the HCQ responsible for its interruption in 58 patients (median duration 7 [3–17] days). Perceived stress was significant (PSS-10 ≥ 27/40) for 11.8% of patients. An anxiety or depressive syndrome was detected in 47.6% and 41.5% of patients, respectively. Scores compatible with post-traumatic stress disorder were found in 39% of patients. Female sex (OR = 4.50 [95% CI: 1.28–15.8]), the presence of financial difficulties (OR = 2.71 [1.30–5.6]) and access to HCQ (OR = 2.07 [1.16–3.69]) during the pandemic were significantly associated with the presence of post-traumatic stress disorder.ConclusionThe COVID-19 pandemic has caused many difficulties for patients with LS, with a high prevalence of mental disorders. These were in particular anxiety or depressive syndromes and states of post-traumatic stress associated with difficulties in accessing treatment or changes in professional activity.