Presence Of HS Research Articles

Salen, salan and salalen zinc(II) complexes in the interaction with HS-: time-resolved fluorescence applications.

In the current work we investigate the route of interaction of a newly synthesized family of zinc complexes with HS- by a plethora of different spectroscopic techniques. A computational analysis on the time dependent density functional theory (TD-DFT) level explored the overall fluorescence properties of the title complexes and their different fluorescence responses to HS-. Time-resolved fluorescence experiments were also performed and highlight the great potential of the current systems to be implemented as HS- fluorescent sensors.

Interaction between carbon steel and low-pH bentonitic cement grout in anoxic, high temperature (80 °C) and spatially heterogeneous conditions

Anoxic corrosion processes impacting carbon steel samples for both intimate and imperfect metal/ low-pH bentonitic cement grout (BCG) contacts were studied at 80 °C. SEM, XRD and µ-Raman spectroscopy analyses supported by geochemical modelling allowed a full characterization of the corrosion mechanism. Steel in direct contact with BCG suffered from localized corrosion (pits measuring up to 160 µm in depth after 150 days of exposure) principally triggered by the presence of HS-. Depending on silicate and sulphide ingress from the BCG towards the interface, neoformed magnetite may be converted to iron silicates and/or iron sulphides.

Electrochemical performance of low-alloy steel and low-carbon steel immersed in the simulated pore solutions of alkali-activated slag/steel slag pastes in the presence of chlorides

The corrosion behaviour of different steels immersed in the simulated pore solutions was investigated using electrochemical measurements, XPS, and SEM/EDS. The results showed that the incorporation of granulated blast furnace slag increased the content of HS− which inhibited the passivation through forming the Fe-S complex. The presence of HS− increased the film thickness but the corrosion resistance was still low due to the porous structure of Fe-S complex on the surface. Severe active corrosion occurred on low-carbon steels in the presence of chlorides while scanty pitting was observed for low-alloy steels attributed to the existence of Cr inside pits.

Interaction mechanism between CO and H2S over CuFe2O4 oxygen carrier during chemical-looping combustion: A DFT study

During the chemical-looping combustion process, CO as an important part of syngas and H2S as a common sulfur compound inevitably coexist in the fuel. Based on the density functional theory and periodic structure model, the interaction mechanism between CO and H2S over the O-defective CuFe2O4 surface was comprehensively investigated. The results show that the adsorption energies of adsorbates on the O-defective surface are in the order of S* (−205.42 kJ/mol) > HS* (−191.37 kJ/mol) > CO (−44.88 kJ/mol) > H2S* (−28.97 kJ/mol). CO adsorption over the O-defective surface is dominant as compared to H2S adsorption. The adsorption energies of CO in the presence of H2S, HS* and S* are − 73.21, −255.98 and − 105.35 kJ/mol, respectively. The adsorption strength of CO over the O-defective surface was enhanced in the presence of HS* or S*. The presence of CO* will greatly limit the H2S dehydrogenation process, especially for the second dehydrogenation step. The energy barriers of CO oxidation with the participation of H2S*, HS* and S* are 69.66, 51.42 and 14.19 kJ/mol, respectively. COS may be produced form the reaction between CO and S* with an energy barrier of 27.13 kJ/mol, following the Eley–Rideal reaction mechanism. CuFe2O4 oxygen carrier exhibits good anti-sulfur ability because the reaction of CuFe2O4 with CO and H2S kinetically prefers the CO oxidation pathway rather than the COS formation pathway.

Paper-Strip-Based Sensors for H2S Detection: A Proof-of-Principle Study.

In this work, the authors explored the interaction of a suite of fluorescent zinc complexes with H2S. The authors provide evidence that HS− binds the zinc center of all the complexes under investigation, allowing them to possibly function as sensors by a ‘coordinative-based’ approach. Naked-eye color changes occur when treating the systems with HS−, so the fluorescence responses are modulated by the presence of HS−, which has been related to a change in the energy level and coupling of excited states through a computational study. The results show the potential of the systems to function as HS−/H2S colorimetric and fluorescent sensors. Paper-strip-based sensing experiments foresee the potential of using this family of complexes as chemosensors of HS− in more complex biological fluids.

Helicobacter pylori Infection Is Associated With Carotid Intima and Media Thickening: A Systematic Review and Meta-Analysis.

Background Helicobacter pylori (H. pylori) infection affects ≈4.4 billion people worldwide. Several studies suggest that this pathogen impacts the digestive system, causing diverse and severe conditions, and results in extragastrointestinal disorders like vascular diseases. Our study aims to examine the association between H. pylori infection and carotid intima‐media thickness.Methods and ResultsElectronic databases (MEDLINE, Embase, CENTRAL, Web of Science, and Scopus) were searched for studies, comparing the thickness of the carotid intima‐media in H. pylori–infected and noninfected individuals listed until October 20, 2020. Statistical analyses were performed using the random effects meta‐analysis of model of weighted mean differences with the corresponding 95% CI using the DerSimonian and Laird method. The protocol was registered in advance in PROSPERO (International Prospective Register of Systematic Reviews; CRD42021224485). Thirteen studies were found meeting inclusion criteria for our systematic review and meta‐analysis, presenting data on the thickness of the carotid intima‐media considering the presence of H. pylori infection. Altogether, 2298 individuals’ data were included (1360 H. pylori positive, 938 negative). The overall carotid intima‐media thickness was significantly larger among infected patients compared with uninfected participants (weighted mean difference: 0.07 mm; 95% CI, 0.02–0.12; P=0.004; I2=91.1%; P<0.001). In case of the right common carotid artery, the intima‐media thickening was found to be significant as well (weighted mean difference, 0.08 mm; 95% CI, 0.02–0.13, P=0.007; I2=85.1%; P<0.001), while it showed no significance in the left common carotid artery (weighted mean difference, 0.12 mm; 95% CI, −0.05 to 0.28, P=0.176; I2=97.4%; P<0.001).Conclusions H. pylori infection is associated with increased carotid intima‐media thickness. Therefore, the infection may indirectly contribute to the development of major vascular events.

Heyde syndrome: prevalence and outcomes in patients undergoing transcatheter aortic valve implantation

BackgroundHeyde syndrome (HS) is known as the association of severe aortic stenosis (AS) and recurrent gastrointestinal bleeding (GIB) from angiodysplasia. Data on the prevalence of HS and results after TAVI remain scarce.Methods2548 consecutive patients who underwent TAVI for the treatment of AS from 2008 to 2017 were evaluated for a history of GIB and the presence of HS. The diagnosis of HS was defined as a clinical triad of severe AS, a history of recurrent GIB, and an endoscopic diagnosis of angiodysplasia. These patients (Heyde) were followed to investigate clinical outcomes, bleeding complications and the recurrence of GIB and were compared to patients with GIB unrelated to HS (Non-Heyde).ResultsA history of GIB prior to TAVI was detected in 190 patients (7.5%). Among them, 47 patients were diagnosed with HS (1.8%). Heyde patients required blood transfusions more frequently compared to Non-Heyde patients during index hospitalization (50.0% vs. 31.9%, p = 0.03). Recurrent GIB was detected in 39.8% of Heyde compared to 21.2% of Non-Heyde patients one year after TAVI (p = 0.03). In patients diagnosed with HS and recurrent GIB after TAVI, the rate of residual ≥ mild paravalvular leakage (PVL) was higher compared to those without recurrent bleeding (73.3% vs. 38.1%, p = 0.05).ConclusionA relevant number of patients undergoing TAVI were diagnosed with HS. Recurrent GIB was detected in a significant number of Heyde patients during follow-up. A possible association with residual PVL requires further investigation to improve treatment options and outcomes in patients with HS.Graphic abstract

The Role and Clinical Implications of the Retinoblastoma (RB)-E2F Pathway in Gastric Cancer.

Gastric cancer is the most common malignant tumor in the digestive tract, with very high morbidity and mortality in developing countries. The pathogenesis of gastric cancer is a complex biological process mediated by abnormal regulation of proto-oncogenes and tumor suppressor genes. Although there have been some in-depth studies on gastric cancer at the molecular level, the specific mechanism has not been fully elucidated. RB family proteins (including RB, p130, and p107) are involved in cell cycle regulation, a process that largely depends on members of the E2F gene family that encode transcriptional activators and repressors. In gastric cancer, inactivation of the RB-E2F pathway serves as a core transcriptional mechanism that drives cell cycle progression, and is regulated by cyclins, cyclin-dependent kinases, cyclin-dependent kinase inhibitors, p53, Helicobacter pylori and some other upstream molecules. The E2F proteins are encoded by eight genes (i.e. E2F1 to E2F8), each of which may play a specific role in gastric cancer. Interestingly, a single E2F such as E2F1 can activate or repress transcription, and enhance or inhibit cell proliferation, depending on the cell environment. Thus, the function of the E2F transcription factor family is very complex and needs further exploration. Importantly, the presence of H. pylori in stomach mucosa may affect the RB and p53 tumor suppressor systems, thereby promoting the occurrence of gastric cancer. This review aims to summarize recent research progress on important roles of the complex RB-E2F signaling network in the development and effective treatment of gastric cancer.

Association of hepatic steatosis with epicardial fat volume and coronary artery disease in symptomatic patients.

This study aims to investigate whether HS-when associated with an excessive amount of epicardial adipose tissue-correlates with CAD in subjects with symptoms suggestive of CVD. CCTA images, demographic and clinical variables of 1.182 individuals were retrieved: semi-automated measurements for EFV, CAC, and MLD were obtained. Individuals were grouped into three categories according to the presence of CAD, resulting in absent (CAD0), non-obstructive (CAD1) or obstructive (CAD2) disease-groups, and into two categories based on the presence of HS (with no HS, named HS-, and with HS, named HS+). EFV was significantly higher in HS+ than in HS- group (p < 0.001), whereas MLD was lower in CAD+ than in CAD- subjects (p < 0.001). Two predictive models for CAD were tested: the former included clinical risk factors for CAD along with age, gender, EFV and MLD, whereas the latter did not include clinical variables. The logistic regression analysis of the second proposed model reliably discriminated CAD0 from CAD1 and CAD2 (AUC of 0.712, range 0.682-0.742). Lower MLD was associated with increased EFV, and MLD-as a marker of HS-discriminate symptomatic patients with CAD from whom without.

Ecological co-benefits from sea cucumber farming: Holothuria scabra increases growth rate of seagrass

Sea cucumber aquaculture is increasing in extent and importance throughout the Indo-Pacific region, supplying a luxury seafood market in Asia. In this context, the grow-out of hatchery-bred juveniles in community-farmed pens is proving to be a viable model, providing increased income security and alternative livelihood options to resource-limited communities. Here, we report a study of the impacts of such sea cucumber farming on the growth of seagrass (a favourable habitat for the animals) at a village-scale aquaculture site in southwest Madagascar. Using experiments, we found that the presence of the hatchery-bred sea cucumberHolothuria scabra(sandfish), at stocking densities of 300 g m-2(similar to the density used in the farmed pens, but relatively high for natural populations), resulted in a large (~30%), statistically significant increase in the leaf extension rate of the locally dominant seagrass speciesThalassia hemprichii. However, the other dominant seagrass species,Cymodocea serrulata, did not significantly change its leaf extension rate in the presence ofH. scabra. Since seagrass is a globally important coastal habitat, supporting high biodiversity, carbon sequestration, shoreline stability and nursery grounds for commercial and small-scale fisheries, the positive effect ofH. scabrafarming on the growth rate of at least one dominant seagrass species implies potential important ecological co-benefits. These co-benefits ofH. scabrafarming are likely to be relevant across the tropical Indo-Pacific coastlines, where this species is cultured.

Fluorescent salen-type Zn(II) Complexes As Probes for Detecting Hydrogen Sulfide and Its Anion: Bioimaging Applications.

In this work, we investigate the mode of interaction of a family of fluorescent zinc complexes with HS– and H2S. Different experiments, performed by diverse spectroscopic techniques, provide evidence that HS– binds the zinc center of all the complexes under investigation. Treatment with neutral H2S exhibits a markedly different reactivity which indicates selectivity for HS– over H2S of the systems under investigation. Striking color changes, visible to the naked eye, occur when treating the systems with HS– or by an H2S flow. Accordingly, also the fluorescence is modulated by the presence of HS–, with the possible formation of multiple adducts. The results highlight the potential of the devised systems to be implemented as HS–/H2S colorimetric and fluorescent sensors. Bioimaging experiments indicate the potential of using this class of compounds as probes for the detection of H2S in living cells.

Interaction mechanism among CO, H2S and CuO oxygen carrier in chemical looping combustion: A density functional theory calculation study

When using coal-derived syngas or coal as fuel in chemical looping combustion (CLC), CO as a representative pyrolysis/gasification product and H2S as the main sulfurous gas coexist in fuel reactor. Either CO or H2S can absorb on the surface of CuO (the active component of Cu-based oxygen carriers), and reactions will occur among them. In this study, density functional theory (DFT) calculations are conducted to investigate the interaction among H2S, CO, and CuO, including: the reaction between CO and H2S over CuO particle, the influence of CO on the H2S dissociation and further reaction process, and the impact of H2S dissociation products on CO oxidation. Firstly, the co-adsorption results suggest that H2S might directly react with CO to produce COS via the Eley–Rideal mechanism, while CO prefers to react with HS* or S* via the Langmuir–Hinshelwood mechanism. This means that the reaction mechanisms between CO and H2S will change as the H2S dissociation proceeds, which has already been forecasted by the co-adsorption energies and verified by all of potential Eley–Rideal and Langmuir–Hinshelwood reaction pathways. Then, the influence of CO on the H2S dissociation process is examined, and it is noted that the presence of CO greatly limits the dissociation of H2S due to the increased energy barrier of the rate-determining dehydrogenation step. Furthermore, the impact of H2S dissociation products on CO oxidation by CuO is also investigated. The presence of H2S and S* significantly supresses the CO oxidation activity, while the presence of HS* slightly promotes the CO oxidation activity. Finally, the complete interaction mechanisms among H2S, CO, and CuO are concluded. It should be noted that COS will be inevitably produced via the Langmuir–Hinshelwood reaction between surface S* and CO*, which is prior to H2O generation and subsequent sulfidation reaction.

Clinical features of subungual melanoma according to the extent of Hutchinson’s nail sign: a retrospective single‐centre study

Hutchinson's nail sign (HS) is among the diagnostic criteria for subungual melanoma (SUM). However, there is minimal evidence supporting the overall clinical significance of HS in SUM. To identify clinicopathological features of SUM according to the extent of HS. Retrospective cohort study was performed with consecutive SUM patients at a single centre from January 2006 to December 2017. The extent of HS was defined by the number of affected nail folds (range 0-4). Comparison groups were organized as follows: patients with HS (affecting ≥1 nail folds) vs. without HS; patients with HS affecting ≥2 nail folds vs. HS affecting <2 nail folds; patients with HS affecting ≥3 nail folds vs. HS affecting <3 nail folds. Clinicopathological characteristics of SUM were compared between the groups. Sixty-one SUM patients were included. Forty-six (75.4%) exhibited HS; 22 (47.8%) on a toe and 24 (52.2%) on a finger. In multivariate analysis, nail destruction [hazard ratio (HR), 10.00; 95% confidence interval (CI), 2.61-38.30; P=0.001] was significantly associated with the presence of HS and amputation was significantly associated with HS affecting ≥2 nail folds (HR, 4.75; 95% CI, 1.36-16.61; P=0.015). High T stage (HR, 1.85; 95% CI, 1.20-2.85; P=0.005, Fig. 2) was significantly associated with HS appearing in ≥3 nail folds. Besides its value of detecting SUM, HS provides useful clinical information. The number of nail folds exhibiting HS could be a useful clinical clue for planning therapeutic strategies for SUM.

A Metallosupramolecular Coordination Polymer for the 'Turn-on' Fluorescence Detection of Hydrogen Sulfide.

A coumarin based probe for the efficient detection of hydrogen sulfide in aqueous medium is reported. The investigated coumarine‐based derivative forms spherical nanoparticles in aqueous media. In presence of Pd2+, a metallosupramolecular coordination polymer is formed, which is accompanied by quenching of the coumarin emission at 390 nm. Its Pd2+ complex could be used as a probe for chemoselective detection of monohydrogensulfide (HS−). Presence of HS− leads to a'turn‐on' fluorescence signal, resulting from decomplexation of Pd2+ from the metallosupramolecular probe. The probe was successfully applied for qualitative and quantitative detection of HS− in different sources of water directly collected from sea, river, tap and laboratory drain water, as well as in growth media for aquatic species.

Landscape factors driving the spread of the invasive grass,Hymenachne amplexicaulis, among wetlands in a Florida subtropical grazing land

AbstractWetlands embedded in agroecosystems provide vital ecosystem services (i.e., freeze protection, water retention, nutrient cycling, biodiversity support). However, they are particularly susceptible to invasion by nonnative species. West Indian marsh grass [Hymenachne amplexicaulis(Rudge) Nees] is a major wetland invader in Florida. Despite the documented consequences ofH. amplexicaulisinvasions, the landscape factors influencing the spread of this species are poorly understood. In this study, we asked whether landscape factors associated with wetland isolation, connectivity, and land management influence the presence ofH. amplexicaulisamong wetlands embedded in pastures. We recorded the presence or absence ofH.amplexicaulisin 158 seasonal wetlands embedded in different pasture types (semi-natural vs. intensively managed). Wetland area, isolation from neighboring wetlands, isolation from the nearest source ditch, and connectivity were determined using a geographic information system (GIS). We related landscape factors toH. amplexicaulisusing generalized linear models and model selection based on the second-order Akaike information criterion.Hymenachne amplexicauliswas first detected at the study site in the early 2000s. By 2018, we observed this species in 66% of the surveyed wetlands. The likelihood of observingH. amplexicauliswas higher in wetlands embedded in semi-natural pastures and higher in less isolated wetlands, especially when connected to a ditch. These results indicate thatH. amplexicaulisspreads both overland (during seasonal flooding) and via the ditch network. Future work is needed to understand whether seeds or stolons are the primary invasion propagule and whether the species forms a persistent seed bank that could slow down restoration efforts. Additionally, further research is required to understand the ecological impact of this highly invasive plant in Florida wetlands.

Late drug-resistance in mild MTLE: Can it be influenced by preexisting white matter alterations?

To identify early structural alterations preceding the development of drug-resistance in mild mesial temporal lobe epilepsy (mMTLE), a drug-responsive syndrome ideal for investigating epilepsy pathophysiology and potential prognostic markers of long-term clinical outcome, using magnetic resonance imaging (MRI) at baseline and after 12-year follow-up. Since 2002, a total of 55 participants with a baseline diagnosis of mMTLE underwent three-dimensional (3D) T1 1.5T MRI. Based on long-term outcome (follow-up 12±3years), we identified 39 patients with stable mMTLE (smMTLE) and 16 patients who had developed drug-resistance overtime (refractory MTLE [rMTLE]). At follow-up, 21 smMTLE and 13 rMTLE patients underwent 3T-MRI including diffusion-weighted scans. Structural images were processed using longitudinal voxel-based morphometry and standard Freesurfer analysis. Statistical analyses were carried out accounting for age, age at onset, gender, hippocampal volume, and hippocampal sclerosis (Hs). Patients presented similar demographic, clinical, and Hs features. White matter volume of the arcuate fasciculi, corticospinal tracts, left retrosplenial cingulum, and left inferior longitudinal fasciculus was reduced only in rMTLE patients before the development of drug-resistance. At follow-up, rMTLE showed decreased fractional anisotropy in the corpus callosum, superior longitudinal fasciculi, and major bundles of the right hemisphere. White matter temporal and extratemporal abnormalities are preexisting in patients with mild MTLE who will develop drug-resistance, independently from the presence of Hs. Thus, these changes might be due to an inherited genetic alteration rather than a subordinate worsening after repeated seizures, multiple antiepileptic drugs, or initial precipitating factors.

Reactivity of monohydrogensulfide with a suite of pyridoxal-based complexes: A combined NMR, ESI-MS, UV–visible and fluorescence study

In the present work, we explored the reactivity of HS− with a family of fluorescent metal complexes via a variety of spectroscopic techniques. The complexes under investigation are obtained by complexation of zinc or nickel with pyridoxal-based ligands. More specifically complexes 1 and 2 are zinc complexes namely L1Zn(II) and L2Zn(II) where L1 stands for N,N′-phenylenebis(pyridoxyliminato) and L2 is N,N′-binaphthylenebis(pyridoxyliminato), whereas complex 3 is a nickel complex (L3Ni(II)) where L3 is N,N′-ethylenebis(pyridoxyliminato). A combination of NMR, ESI-MS, UV–vis and fluorescence experiments provide evidence that HS− binds the metal center in the case of complexes 1 and 3 whereas for complex 2, ZnS precipitation and hydrolysis of the organic ligand occur. Fluorescence experiments indicate that in the presence of HS− complex 1 undergoes a consistent fluorescence enhancement whereas for complex 3 the parent fluorescence exhibits a visible quenching. The results highlight the potential of complex 1 to be implemented as a HS− fluorescent sensor via a coordinative-based approach.

Tracking Fe mobility and Fe speciation in subduction zone fluids at the slab-mantle interface in a subduction channel: A tale of whiteschist from the Western Alps

Fluids released by subducting slabs are important to the geochemical evolution of Earth’s crust-mantle system. However, it is still not well constrained for the mobility of redox sensitive elements (like Fe, C or S) in subduction zone fluids, and its effect on the redox property of the overlying mantle wedge and its derived arc magmas. Iron isotope fractionation is sensitive to the redox state and speciation of Fe in fluids, which can potentially provide clues on the oxygen fugacity (fO2) of slab-derived fluids. Whiteschists at the Dora-Maira Massif in the Western Alps have experienced ultrahigh-pressure metamorphism at subarc depths. They are rich in both SiO2 (mostly >65 wt.%) and MgO (4–10 wt.%), and mainly composed of pyrope, quartz/coesite, talc, phengite and kyanite. They were demonstrated to have a granite protolith, but metasomatized by serpentinite-derived Mg-rich fluids at the slab-mantle interface in a subduction channel. Thus these rocks provide an excellent target to explore the fluid-rock interaction by Fe isotopes. The whiteschists show extremely high δ56Fe values of +0.32 to +1.22‰, being much higher than those of +0.10 to +0.38‰ for the surrounding metagranites. The Fe isotope composition of whiteschists significantly deviates from the igneous differentiation trend defined by rocks with basaltic to rhyolitic compositions. The heavy Fe isotope compositions must be produced by a metasomatic process. The much lower Fe2O3 and FeOt contents and Fe3+/∑Fe ratios but higher δ56Fe values for the whiteschists relative to their protolith suggest the reduction of Fe3+ to Fe2+ and the loss of isotopically light Fe, probably in the form of Fe(II)-Cl and/or Fe(II)-(HS) complexes, through saline fluids and/or HS- bearing fluids. The reduction of Fe3+ to Fe2+ and the possible presence of HS- suggests the occurrence of relatively reduced fluids. Such reduced fluids were probably derived from serpentinite dehydration at the slab-mantle interface in the subduction channel. Therefore, the Fe isotope results demonstrate that the fO2 at the slab-mantle interface can be locally highly heterogeneous, leading to various oxidation states in the mantle wedge and arc magmas.

Electrochemical Synthesis of Individual Core@Shell and Hollow Ag/Ag2S Nanoparticles.

This letter presents an electrochemical methodology for structure-tunable synthesis, characterization, and kinetic monitoring of metal-semiconductor phase transformations at individual Ag nanoparticles. In the presence of HS- in aqueous solution, the stochastic collision and adsorption of Ag nanoparticles at a Au microelectrode initiates the partial anodic transformation of Ag to Ag2S at each particle. A single continuous current transient is observed for each Ag nanoparticle reacted. The characteristic shapes of the transients are distinct from previously reported amperometric recordings of electrochemical reactions involving single nanoparticles and are highly uniform at a constant applied potential. The average maximum current increases while the event duration decreases as a function of increasing potential. Independent of applied potential, the electrochemical transformation event abruptly stops after converting ∼80% of the Ag in the nanoparticle to Ag2S, a self-terminating process that does not occur for bulk Ag electrodes under similar conditions. The resulting products are a mixture of core@shell Ag@Ag2S nanoparticles with and without voids in the core, as characterized by transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDX). Both the frequency and size of voids increase at more positive potentials. The average size of the core@shell nanoparticles determined by coulometric analysis of the current transients agrees well with TEM measurements.

Anion binding ability and cytotoxicity of a selective colorimetric chemosensor for H2S based on Zn(Ⅱ) complex

A zinc(II) complex–based selective colorimetric chemosensor for H2S was synthesized. The ligand and complex crystals were obtained, and the molecular structures were confirmed by single-crystal X-ray diffraction analysis in addition to electrospray ionization high resolution mass spectrometer, as well as elemental analysis. The photo-physical and recognition properties toward HS– were examined. The complex indicated the presence of HS– with an obvious color change from yellow to red, based on zinc ion displacement mechanism. However no obvious changes were observed in the presence of other anions (AcO−, H2PO4−, F−, Cl−, Br−, I− and SO32−). In addition, the chemosensor was applied to assess HeLa cell cytotoxicity. Our inorganic-reaction based sensor for HS– is simple, easily prepared and efficient. The complex has many potential chemical and analytical applications for the sensing of H2S.