Preschool Children's Exposure Research Articles

The Relationship of Screen Exposure with Sleep Quality and Self-Regulation Skills in Preschool Children

Objective: We aimed to investigate possible links between screen time, self-regulation skills and sleep quality in preschool children. Material and Methods: The study was carried out with 140 mothers with 4-6 years old children who visited the family medicine outpatient clinic between March and May 2022. Children’s age, gender, existing chronic diseases, the most used technological product, purpose of use, time and duration were recorded. Children’s sleep habits were evaluated with the “Children’s Sleep Habits Questionnaire (CSHQ)”, and their self-regulation skills were evaluated with the “Self-Regulation Skills Scale for 4-6 Years-Old Children(Mother Form)(SrSS)”. Results: The median age of the children in our study was 60 (48-72) months. 75/140 of the participants were girls. The most used technological product at home was the smartphone (48.2%). 64% of the participants reported less than 2 hours screen time, 21.6% of them reported between 2-4 hours and 14.4% of them reported over 4 hours. Educational status of mothers (p=0.003) and fathers (p<0.001) of those with a lot of screen exposure was lower. Delay in falling asleep score, one of the CSHQ subscales, was higher in those with screen exposure over 4 hours (p<0.001). Self-regulation skills scale total score (p=0.001), attention (p=0.014), inhibitory control-emotion (p=0.004), and inhibitory control-behavior (p=0.029) sub-scale scores were lower in children with longer screen time. Conclusion: Excessive screen exposure in preschool children is associated with delay in falling asleep and low self-regulation skills.

Tres indicadores de exposición a la lengua y su efecto en la adquisición del léxico de una lengua minoritaria

The current study analyses short Basque CDI questionnaires’ accuracy to measure the effect of the amount of exposure to the language on bilingual children's vocabulary size. Additionally, it compares the predictive ability of three variables related to the amount of exposure: relative input, language of parental communication and parents’ linguistic profile. Data of 2098 children (8–49 months) obtained with the short versions of the Basque CDI (CDI-1vb, CDI-2vb and CDI-3v) revealed (a) these three instruments’ sensibility to measure the effect of language exposure on children's expressive vocabulary, (b) a very similar effect size for the three variables, and (c) an increase in effect size with age: no effect at the age of 8–15 months, small at 16–29 months and large at the age of 30–49 months. Data suggests that parents’ linguistic profile and language of inter-parental communication are indicators equally suitable of preschool children's exposure to the language, or even more so, than input, and leads the authors to claim the inclusion of those factors in the assessment of young children's lexical development, especially in minority languages.

Preschoolers' engagement with screen content and associations with sleep and cognitive development

Preschool children's exposure to screen media and associations with sleep, language, and cognition were investigated along with the time of day of screen exposure, content type, and whether use occurred with someone. Caregivers of Australian children, aged 2 years, 11 months to 5 years, 11 months, answered questions online about the durations children engaged with entertainment, relaxing/calming, and educational content. Fifty-nine percent of children engaged with relaxing/calming content and 86 % with educational, but all children engaged with entertainment content, which became the focus of the analyses. Average daily durations engaged with relaxing and educational content were 1 h each and 2 h for entertainment content. Longer time spent engaged with entertainment content was associated with shorter sleep duration and poorer sleep quality. The interaction between screen time and usage at night vs. daytime only was non-significant suggesting that the association with sleep duration was similar regardless of time of day of usage. Greater screen time also predicted lower communication and problem solving scores, and more attention difficulties. Engaging in screen content with someone else was associated with poorer problem solving skills, whereas engaging alone was associated with better problem solving. The findings here indicate that preschoolers largely engage in entertainment content and this has implications for their sleep even when screen engagement predominantly occurs during the day. Greater screen time also has implications for cognitive and language development raising questions about the time children spend on screens that could be spent on activities that better support development.

Identification of Phthalates from Artificial Products in Chinese Kindergarten Classrooms and the Implications for Preschool Children's Exposure Assessments.

Phthalates are typical chemical pollutants in kindergarten classrooms since numerous artificial products (e.g., polyvinyl chloride (PVC) floorings, soft polymers and plastic toys) that might contain phthalates are widely distributed in kindergarten classrooms. Although Chinese preschool children spend a considerable amount of their waking hours (>8 h/day) in kindergartens, phthalate exposure in such indoor environment has not been given much attention. In this study, the mass fractions of six phthalates in twenty-six artificial products (fifteen flat decoration materials and eleven plastic toys) commonly found in Chinese kindergarten classrooms were measured. Di-2-ethylhexyl phthalate (DEHP) was the most predominant compound in all materials. The emission characteristics of the DEHP from these materials were further investigated. The measured emission characteristics were used for predicting multi-phase DEHP concentrations in kindergarten classrooms by applying a mass transfer model. The modeled concentrations were comparable with those measured in the real environment, indicating that these products might be the major sources of DEHP in Chinese kindergarten classrooms. Preschool children’s exposure to DEHP was found to be 0.42 μg/kg/day in kindergartens under baseline conditions, accounting for 18% of the total exposure to DEHP in Chinese indoor environments.

Handling Adverse Effects of Digital Screen Time on Preschool Children: Looking beyond Limiting Screen Time

Author analyses excessive screen time issues with preschool children, and how counsellors can take a better counselling approach with parents while keeping in perspective Erik Erikson’s Theory of psychosocial development impacting the child by the age of 5 years. Preschool children spend more than 2.5 hours per day on digital screens; this is against recommended guidelines of less than 1 hour per day by * WHO and ** AAP. A literature review of research papers from online *** libraries by the author found that only a small percentage of children met the recommended guidelines resulting in the risk of language disorders, delayed development of physical, motor skills and cognitive abilities, obesity, sleep problems, depression and anxiety due to screen exposure. The loneliness of children is found to be the primary reason for the excessive screen time. The author suggests that counsellors help parents look beyond limiting a child’s screen time alone and improve the parental attitude toward the child’s behaviour which is the biggest barrier in managing a child’s screen time. The author’s contribution is the ‘SALT’ counselling approach emphasising listening Support, finding Alternatives, Loneliness and Time in this digital era to cater to all types of child learners - visual, auditory, and kinesthetic. Why is your paper of interest to readers? Exposure of preschool children to digital devices is more than double the recommended screen time, hampering a child’s critical personality development required as per Erik Erikson’s Theory. Counsellors need to look at other associated factors beyond screen time which affect children adversely and which are more important than just the screen time limitation prescribed as per government guidelines. Focus :SE Asia and Outside SE Asia (No IRB approval is sought as the paper is based on secondary research.)

Preschoolers and Advertising: A Systematic Literature Review and Future Research Agenda on the Effects of Advertising on Preschool Children

Preschool children’s (ages three to five) advertising exposure is expected to increase over the coming years, mainly due to their changed media use. This increasing exposure might be problematic as research has shown a correlation with unfavorable outcomes, such as obesogenic eating tendencies. However, research on preschoolers and advertising is not unequivocal, and, to the best of our knowledge, no literature reviews are currently available. Therefore, this article aims to provide an in-depth analysis of the academic literature (N = 92) on advertising and preschool children published between 1980 and 2021 and so propose a future research agenda. The analysis revealed that little attention has been paid to preschool children’s exposure to and impact from embedded advertising formats (e.g., YouTube advertising). The main interest in the included studies was on preschool children’s nutrition, which was reflected in both the constructs studied (e.g., food preferences) and the publication outlets (e.g., Appetite). Further, studies focusing on behavioral outcomes, such as purchase requests, are limited, and therefore little is known about the long-term impact of advertising exposure in preschool children. Finally, most studies do not explicitly disclose a theoretical framework. Future studies should address these issues to catch up with preschool children’s advertising reality.

Is Time Spent Outside the Family Home a Risk Factor for Lead Exposure in Pre-School Children Living in Broken Hill?

Broken Hill is amongst a group of communities internationally that are at greater risk from lead due to active or historical lead industries. Current evidence suggests there is no safe level of lead for young children. This paper describes places outside the family home where young Broken Hill children spend time and considers the potential for this to contribute to lead risk. We interviewed 65 families of children 3 years old or younger and detailed the top five places children spent time at outside the family home. Exposure to private residences outside the family home was recorded for most (88%) young children. Nearly two thirds stayed there five or more hours per week. Most children went there on a weekly basis over many months (median, 12 months), increasing the likelihood of exposure to lead hazards. Further investigation of the lead hazard and risk behaviour of children at these residences would assist in developing guidelines for remediation of the lead hazard for all private residences in Broken Hill. This approach to elucidating the potential sources and pathways of lead and other heavy metal exposures for young children may have merit in other settings where comprehensive zonal remediation is not feasible or may not be warranted.

Fluoride exposure and factors affecting dental caries in preschool children living in two areas with different natural levels of fluorides

BackgroundSuccessful oral health interventions must be based on the specific needs of the population that they serve. Evaluation of habits related to dental caries development and estimation of fluoride exposure in a target group of young patients helps to plan effective and safe caries prevention strategies. ObjectivesThe study aimed to evaluate factors affecting dental caries experience and sources of fluoride exposure in preschool children living in two areas: with optimal and low natural content of fluoride in drinking water. Materials and methodsThe study included a group of 73 children of both sexes aged 4–7 years attending two kindergartens in Środa Wielkopolska and Turek (Wielkopolska Voivodeship, Poland), where the content of fluoride in drinking water according to data obtained in the sanitary station ranged from 0.68 to 0.74 mg/L (optimal concentration of fluoride) and from 0.19 to 0.30 mg/L (low concentration of fluoride), respectively. Parents of patients completed a survey about diet, hygiene, and dental care, taking into account the child's fluoride exposure. The calibrated dentist assessed the oral health condition using a mirror, a CPI probe, and a headlamp. Oral hygiene was recorded using the Silness and Löe plaque index, caries experience by calculating the numbers of decayed, missing, and filled primary, and permanent teeth (dmf and DMF, respectively) while caries frequency by calculating the percentage of children with caries experience above 0. In order to assess the fluoride concentrations in urine and drinking water, parents were asked to provide a urine sample collected on fasting and a tap water sample. Fluoride concentrations were assessed using a 09–37 (MARAT) fluoride ion-selective electrode and a RAE 111 silver-chloride reference electrode. Statistical analysis was conducted using the data analysis software system Statistica (version 12, StatSoft, Inc. 2014), assuming a statistical significance level p < 0.05. ResultsNo statistically significant differences were found between caries indices of the examined children in each kindergarten (p > 0.05). Urinary fluoride levels were higher in children who tended to swallow toothpaste or used fluoride rinses and positively correlated with fluoride concentrations in the drinking water. Dental caries experience in the examined children depended on the effectiveness and frequency of oral hygiene procedures and dietary habits. ConclusionsThe strategy aimed at improving the oral health of the examined group of children should include accomplishing oral hygiene, promoting a non-cariogenic diet, and, finally, controlling fluoride exposure from at-home fluoride products. Caries prevention program ought to be adjusted to individual characteristics of each child, taking into consideration oral hygiene practices, dietary habits and total fluoride intake.

Screen media exposure in pre-school children in Turkey: the relation with temperament and the role of parental attitudes.

Electronic media have become an important element in the lives of modern children. Devices like televisions, smartphones and tablets are widely used by some parents in order to manage hyperactive, stubborn and impulsive children who need high-intensity stimuli. Consequently, a child`s temperament and parental attitudes affect the duration and frequency of 3-7-year-old children`s screen (television-smartphone-internet) use. Based on this information, the objective of the present study was to evaluate the relation between screen media exposure, the child`s temperament and parental attitudes in 3-7-year-old children. The participants of this study were 210 children of 3 to 7 years of age. Rothbart`s Child Behavior List was used to assess temperament; the Parenting Attitude Research Instrument was used to determine the parental attitudes. Screen media exposure assessment questionnaire, which included questions about the age the child started using the TV, smartphone and/or internet, and the duration of their daily usage, were filled in with the children`s parents. It was found that the increase in activity level, approach and discomfort was negatively correlated to the age the child started watching television, while shyness was positively related to the same phenomenon. The scores of the discomfort temperament subscale had a direct relation to the duration of watching television. Background television is negatively related to attention, inhibitory control, and perceptual sensitivity. Dependency, marital conflict and strictness and authoritarianism parameters were found to be positively related to the duration of playing with a smartphone. Also, in this study we found that negative temperament characteristics adversely affected screen media exposure and poor parenting styles worsen this relationship. Both temperament and parenting styles affect screen media exposure. In addition, it was understood that parenting styles also affect the relation between temperament and screen exposure. Parental information programs on this subject can eliminate the lack of information related to early screen media exposure in preschool children.

Screen Time Exposure in Preschool Children with ADHD: A Cross-Sectional Exploratory Study from South India.

Background:Concern is mounting regarding screen exposure among young children and its association with mental health. Children with attention deficit hyperactivity disorder (ADHD) may be more vulnerable to its effects such as increased externalizing behaviors and problems with language and cognitive development and biological functions such as sleep. We aimed to assess screen exposure in preschool children with ADHD and to study the correlation of screen time with the severity of ADHD and parental stress levels.Methods:Children of age 2.5–6 years, diagnosed with ADHD (n = 56) were included, and details of the total duration of screen exposure, maximum continuous screen exposure time, and types of screen-based devices used, reasons for screen exposure were collected from primary caregivers. ADHD symptom severity was assessed on Conner's Abbreviated Rating Scale. Family interview for stress and coping, adapted for ADHD, was used to measure parental stress.Results:Total screen exposure time in preschool children with ADHD was more than the recommended standards in 80.4% of children, with a median of 140.00 minutes (range: 20–500 minutes). The most commonly used modality was television (98.2%), followed by mobile phones (87.3%), tablets (17.9%), and laptops (10.7%). The severity of ADHD (r = 0.29, P = 0.02) and parent stress levels (r = 0.29, P = 0.03) were positively correlated to increased screen time exposure in the child.Conclusions:Preschool children with ADHD have screen exposure above the recommended duration of one hour/day. Structured parent training programs for children with preschool ADHD and providing developmentally appropriate interventions are essential in curtailing screen time exposure and also to address parental stress.

Excessive screen time is associated with maternal rejection behaviours in pre-school children.

Early childhood screen exposure leads to multiple adverse health events and parents have a major influence on their children's screen time. Our aim was to determine the association between maternal acceptance-rejection/control behaviours and excessive screen exposure in pre-school children. In this cross-sectional descriptive study, children aged 2-5 years who had daily screen time <1 h (n = 76) and >4 h (n = 62) were enrolled. A structured survey form and Parental Acceptance-Rejection/Control Questionnaire were completed by mothers. Total rejection scores were found to be lower in those with screen time <1 h than cases with >4 h (82.7 ± 13.2, 89.3 ± 17.2; P = 0.015). In addition, higher hostility, neglect and reverse-affection scores were detected in excessive screen-exposed group (P = 0.033, P = 0.003, P = 0.047, respectively). Multivariate logistic regression analyses revealed that mothers' low acceptance of their children and high neglect score were associated with excessive screen exposure after adjusting possible confounding factors. The undifferentiated rejection and control behaviours of the mothers had no association with excessive screen exposure. Children with excessive screen time may have a problematic relationship with their mothers. The relationship between parent and child should be examined and corrective actions should be taken.

Elevation of C-reactive protein, P-selectin and Resistin as potential inflammatory biomarkers of urogenital Schistosomiasis exposure in preschool children

BackgroundSchistosomiasis is known to induce inflammatory immune responses. C-reactive protein (CRP), resistin and P-selectin are serological inflammatory markers that rise during the acute stages of infection. Here, we propose such inflammatory biomarkers have a potential for use in urogenital schistosomiasis diagnostic screening for exposure and infection in preschool-aged children.MethodsAs part of a larger study on urogenital schistosomiasis, 299 preschool children aged 1–5 years were included in this cross-sectional study. Parasitological diagnosis was conducted using urine filtration for Schistosoma haemtobium infection, and Kato Katz for S. mansoni infection. Serum levels of P-selectin, resistin, CRP, and antibodies against S. haematobium cercarial antigen preparation (CAP) and soluble worm antigen preparation (SWAP) were measured by ELISA.ResultsOf the 299 participants, 14% were egg positive for S. haematobium. Serology showed 46 and 9% of the participants to have been exposed to S. haematobium cercarial antigens and adult worm antigens, respectively. Levels of P-selectin were significantly higher in participants infected with S. haematobium (egg-positive) than in uninfected participants (p = 0.001). Levels of P-selectin were also higher in those exposed to cercarial antigen than in unexposed participants (p = 0.019). There was a positive correlation between P-selectin and infection intensity (r = 0.172; p = 0.002), as well as with IgM responses to CAP and SWAP (r = 0.183; p = 0.001); (r = 0.333; p < 0.0001) respectively. CRP significantly correlated with IgM responses to CAP (r = 0.133; p = 0.029) while resistin correlated with IgM responses to CAP and SWAP (r = 0.127; p = 0.016); (r = 0.197; p = 0.0004). CRP levels were higher in those exposed to cercarial and adult worm antigens than unexposed participants (p = 0.035); (p = 0.002) respectively, while resistin was higher in participants exposed to cercarial antigen than unexposed participants (p = 0.024).ConclusionIn this preschool population, P-selectin is significantly associated with urogenital schistosome infection and intensity; hence a potential biomarker for infection diagnosis and disease monitoring. The inflammatory biomarkers (P-selectin, Resistin and CRP) were significantly higher in participants exposed to cercarial antigens than unexposed individuals indicating an underlying inflammatory environment.

Indoor phthalate concentrations in residences in Shihezi, China: implications for preschool children's exposure and risk assessment.

Despite the risks associated with phthalate exposure, there are few studies emphasizing preschool children's exposure to phthalates in residences in Northwest China. In this study, seven phthalates from indoor dust samples were measured in 50 residences in Shihezi, China. Preschool children's exposure doses via non-dietary intake were calculated by Monte Carlo simulation. Risk assessment was conducted by comparing the simulated exposure dose with benchmarks for reproductive toxicity and cancer specified in Proposition 65 of California. The detection frequencies for all selected phthalates were more than 75%, with the exception of benzyl butyl phthalate (BBP) and di-n-octyl phthalate (DNOP). Bis(2-ethylhexyl) phthalate (DEHP) was the most principal compound in the dust samples (median = 455 μg/g and 462 μg/g in the bedroom and living room, respectively). The simulation displayed that the median DBP daily intake was 1.5-1.9 μg/day/kg for preschool children in Shihezi, which was considered a high level compared with similar studies around the world. The risk assessment indicated that almost all preschool children face potential reproductive risk due to dibutyl phthalate (DBP) exposure, with medians of hazard index (HI) from 9.6 to 12.4 for all age groups. Therefore, from a children's health perspective, attention should be paid to reducing indoor phthalate pollution and exposure in this area.

Cumulative risk assessment of phthalates exposure in preschool children

Objective: The urine concentrations of phthalate metabolites were used to estimate the cumulative risk assessment in preschool children in Ma'anshan of Anhui province. Methods: Based on the China-Anhui Birth Cohort, the demographic information and urine samples of 3 743 children were collected in Ma'anshan from April 2014 to April 2015. The concentrations of 7 metabolites' [monomethyl phthalate (MMP), monoethyl phthalate (MEP), monobutyl phthalate (MBP), monobenzyl phthalate (MBzP), mono (2-ethylhexyl) phthalate (MEHP), mono (2-ethyl- 5-oxohexyl) phthalate (MEOHP) and mono (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)] of 5 phthalates [dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), butyl benzyl phthalate (BBzP), and di (2-ethylhexyl) phthalate (DEHP)] in the urine samples of the children were measured by solid-phase extration-triple quadrupole high performance liquid chromatography-tandem mass spectrometry-isotope method. In addition, the estimated daily intakes (EDIs) of 5 phthalates were calculated according to the metabolites' concentrations. Cumulative risk assessment was performed using hazard quotient (HQ) and hazard index (HI) methods. Results: The M (Q(R)) of seven metabolite concentrations were 29.58 (18.69-48.26), 26.65 (13.44-56.09), 256.86 (150.99-438.51), 0.12 (0.04-0.32), 6.27 (3.71-11.13), 17.94 (11.94-28.42) and 24.80 (16.05-40.32) μg/g creatinine, respectively. For the EDIs of 5 phthalates, DBP ranked first, followed by DEHP, DMP, DEP and BBzP with the M (Q(R)) of 7.54 (4.41-12.85), 3.35 (2.20-5.42), 0.75 (0.47-1.24), 0.71 (0.36-1.52) and 0.003 (0.001-0.009) μg/(kg·d), respectively. The HQ and HI varied with age, gender and sampling season, the differences were significant (P<0.05). Conclusions: These results indicated that risk of cumulative exposure to phthalates was high in preschool children aged 3-6 years in Ma'anshan. Age, gender and sampling season were influencing factors.

Elevated biomarkers of sympatho-adrenomedullary activity linked to e-waste air pollutant exposure in preschool children

Air pollution is a risk factor for cardiovascular disease (CVD), and cardiovascular regulatory changes in childhood contribute to the development and progression of cardiovascular events at older ages. The aim of the study was to investigate the effect of air pollutant exposure on the child sympatho-adrenomedullary (SAM) system, which plays a vital role in regulating and controlling the cardiovascular system. Two plasma biomarkers (plasma epinephrine and norepinephrine) of SAM activity and heart rate were measured in preschool children (n = 228) living in Guiyu, and native (n = 104) and non-native children (n = 91) living in a reference area (Haojiang) for >1 year. Air pollution data, over the 4-months before the health examination, was also collected. Environmental PM2.5, PM10, SO2, NO2 and CO, plasma norepinephrine and heart rate of the e-waste recycling area were significantly higher than for the non-e-waste recycling area. However, there was no difference in plasma norepinephrine and heart rate between native children living in the non-e-waste recycling area and non-native children living in the non-e-waste recycling area. PM2.5, PM10, SO2 and NO2 data, over the 30-day and the 4-month average of pollution before the health examination, showed a positive association with plasma norepinephrine level. PM2.5, PM10, SO2, NO2 and CO concentrations, over the 24 h of the day of the health examination, the 3 previous 24-hour periods before the health examination, and the 24 h after the health examination, were related to increase in heart rate. At the same time, plasma norepinephrine and heart rate on children in the high air pollution level group (≤50-m radius of family-run workshops) were higher than those in the low air pollution level group. Our results suggest that air pollution exposure in e-waste recycling areas could result in an increase in heart rate and plasma norepinephrine, implying e-waste air pollutant exposure impairs the SAM system in children.

Decreased lung function with mediation of blood parameters linked to e-waste lead and cadmium exposure in preschool children

Blood lead (Pb) and cadmium (Cd) levels have been associated with lower lung function in adults and smokers, but whether this also holds for children from electronic waste (e-waste) recycling areas is still unknown. To investigate the contribution of blood heavy metals and lung function levels, and the relationship among living area, the blood parameter levels, and the lung function levels, a total of 206 preschool children from Guiyu (exposed area), and Haojiang and Xiashan (reference areas) were recruited and required to undergo blood tests and lung function tests during the study period. Preschool children living in e-waste exposed areas were found to have a 1.37 μg/dL increase in blood Pb, 1.18 μg/L increase in blood Cd, and a 41.00 × 109/L increase in platelet counts, while having a 2.82 g/L decrease in hemoglobin, 92 mL decrease in FVC and 86 mL decrease in FEV1. Each unit of hemoglobin (1 g/L) decline was associated with 5 mL decrease in FVC and 4 mL decrease in FEV1. We conclude that children living in e-waste exposed area have higher levels of blood Pb, Cd and platelets, and lower levels of hemoglobin and lung function. Hemoglobin can be a good predictor for lung function levels.

Using silicone wristbands to evaluate preschool children's exposure to flame retardants

Silicone wristbands can be used as passive sampling tools for measuring personal environmental exposure to organic compounds. Due to the lightweight and simple design, the wristband may be a useful technique for measuring children's exposure. In this study, we tested the stability of flame retardant compounds in silicone wristbands and developed an analytical approach for measuring 41 flame retardants in the silicone wristband in order to evaluate exposure to these compounds in preschool-aged children. To evaluate the robustness of using wristbands to measure flame retardants, we evaluated the stability of 3 polybrominated diphenyl ethers (BDEs), and 2 organophosphate flame retardants (OPFRs) in wristbands over 84 days and did not find any evidence of significant loss over time at either 4 or −20°C (p>0.16). We recruited a cohort of 92 preschool aged children in Oregon to wear the wristband for 7 days in order to characterize children's acceptance of the technology, and to characterize their exposure to flame retardants. Seventy-seven parents returned the wristbands for analysis of 35 BDEs, 4 OPFRs, and 2 other brominated flame retardants although 5 were excluded from the exposure assessment due to protocol deviations (n=72). A total of 20 compounds were detected above the limit of quantitation, and 11 compounds including 4 OPFRs and 7 BDEs were detected in over 60% of the samples. Children's gender, age, race, recruitment site, and family context were not significantly associated with returning wristbands or compliance with protocols. Comparisons between flame retardant data and socio-demographic information revealed significant differences in total exposures to both ΣBDEs and ΣOPFRs based on age of house, vacuuming frequency, and family context. These results demonstrate that preschool children in Oregon are exposed to BDEs that are no longer being produced in the United States and to OPFRs that have been used as an alternative to polybrominated compounds. Silicone wristbands were well tolerated by young children and were useful for characterizing personal exposure to flame retardants that were not bound to particulate matter.

Preschool children's exposure to story grammar elements during parent–child book reading

Twenty‐three preschool‐age children, 3;6 (years; months) to 4;1, were videotaped separately with their mothers and fathers while each mother and father read a different unfamiliar storybook to them. The text from the unfamiliar storybooks was parsed and coded into story grammar elements and all parental extratextual utterances were transcribed and coded for (1) their relationship to the story grammar elements found within the storybook, and (2) the natural strategies parents used to direct their children's attention to these elements. Children's overall exposure to story grammar elements during book reading was also explored for its relationship to their language abilities. Results indicated that parents focused significantly more on the resolution, attempt, and consequence compared to the initiating event and plan, and most frequently used the text and pictures as strategies for recruiting their children's attention to the story grammar elements within the book. In addition, the frequency of parental utterances related to story grammar elements was negatively correlated with children's language abilities. This study did not examine the complexity or depth of parental utterances related to story grammar elements. These findings provide initial evidence that children may derive their understanding of story grammar at least in part through their parents' extratextual discussions during parent–child book reading.

Indoor phthalate concentration in residential apartments in Chongqing, China: Implications for preschool children's exposure and risk assessment

Abstract Six phthalates – dimethyl phthalate (DMP), diethyl phthalate (DEP), di(isobutyl) phthalate (DiBP), di(n-butyl) phthalate (DnBP), butyl benzyl phthalate (BBzP) and di(2-ethylhexyl) phthalate (DEHP) – in indoor gas-phase and dust samples were measured in thirty residential apartments for the first time in Chongqing, China. Monte-Carlo simulation was used to estimate preschool children's exposure via inhalation, non-dietary ingestion and dermal absorption based on gas-phase and dust concentrations. Risk assessment was evaluated by comparing the modeled exposure doses with child-specific benchmarks specified in California's Proposition 65. The detection frequency for all the targeted phthalates was more than 80% except for BBzP. DMP was the most predominant compound in the gas-phase (median = 0.91 μg/m 3 and 0.82 μg/m 3 in living rooms and bedrooms, respectively), and DEHP was the most predominant compound in the dust samples (median = 1543 μg/g and 1450 μg/g in living rooms and bedrooms, respectively). Correlation analysis suggests that indoor DiBP and DnBP might come from the same emission sources. The simulations showed that the median DEHP daily intake was 3.18–4.28 μg/day/kg-bw in all age groups, suggesting that it was the greatest of the targeted phthalates. The risk assessment indicated that the exposure doses of DnBP and DEHP exceeded the child-specific benchmarks in more than 90% of preschool children in Chongqing. Therefore, from a children's health perspective, efforts should focus on controlling indoor phthalate concentrations and exposures.

Decreased blood hepatitis B surface antibody levels linked to e-waste lead exposure in preschool children

Lead (Pb) is a widespread environmental contaminant that can profoundly affect the immune system in vaccinated children. To explore the association between blood Pb and HBsAb levels in children chronically exposed to Pb, we measured hepatitis B surface antibody (HBsAb) titers, to reflect the immune response in the children of Guiyu, an electronic and electrical waste (e-waste) recycling area well known for environmental Pb contamination. We performed secondary exploratory analyses of blood Pb levels and plasma HBsAb titers in samples, taken in two phases between 2011 and 2012, from 590 children from Guiyu (exposed group) and Haojiang (reference group). Children living in the exposed area had higher blood Pb levels and lower HBsAb titers compared with children from the reference area. At each phase, generalized linear mixed models (GLMMs) showed that HBsAb titers were significantly negatively associated with child blood Pb levels. This work shows that a decreased immune response to hepatitis B vaccine and immune system might have potential harm to children with chronic Pb exposure. Importantly, nearly 50% of chronically exposed children failed to develop sufficient immunity to hepatitis in response to vaccination. Thus different vaccination strategies are needed for children living under conditions of chronic Pb exposure.