Packaging food safety is a stone corner in fresh food's production and its commercialization process. Recently, researchers studied the hazardous (detection and determination) of migrated compounds from printed packaging film. A new direction in wastewater treatment of hazardous migratory substances in food packaging is urgently needed. Cellulose acetate (CA) and strontium titanate (SrTiO3) were prepared to accelerate the photocatalytic degradation of print waste material. The prepared films contained different percentages of SrTiO3 (ST) (10, 5, 2.5 and zero % (wt/wt)). The characterizations of prepared cellulose acetate/ SrTiO3 films (CA/ST) were investigated using ATR-FTIR, SEM, EDX, XRD, UV and BET. The photocatalytic degradation study observed that 10 % strontium titanate/cellulose acetate affirmed the excellent where catalytic degradation was carried out in a shorter time (60 min). The reusability of all films was assigned five times with approximately the same efficiency. The antimicrobial activity of the CA/ST films against the most infectious contaminated microorganisms emphasizes that the prepared films can be described as broad-spectrum antimicrobial agents. The dual rule of prepared films as photocatalyst and antimicrobial agents give a great advantage to safe water from agri-food plastic transparent printed packaging.