Event Abstract Back to Event Attentional modulation of the tuning of neurons in area MT to the direction of transparent motion Anja Lochte1*, Valeska Stephan1, Vladislav Kozyrev1, 2, Annette Witt2, 3 and Stefan Treue1 1 German Primate Center, Germany 2 Bernstein Center for Computational Neuroscience, Germany 3 Max Planck Institute for Dynamics and Self-Organization , Germany Transparent motion perception requires the segmentation and separate representation of multiple motion directions within the same part of visual space. In a previous study we recorded responses from direction-selective neurons in macaque middle temporal area (MT) to unattended bidirectional random dot patterns (RDPs; Treue et al., 2000). The profile of responses to such transparent motion patterns is the scaled sum of responses to the individual components, showing two peaks when the angle between the component directions exceeds the neuron’s tuning width.Here we investigated the influence of attention on the representation of the direction components of transparent motion by recording from MT in an attentional paradigm. Our question was, whether the effects of attention can be better characterized as a modulation of the population response in MT or as a modulation of two independent neuronal populations, each encoding one of the two directions (as might be expected to happen in area V1). Two monkeys were trained on a task, where an initial cue indicated the relevant direction of motion in a given trial. Two RDPs were then presented, moving within a common stationary aperture, sized and positioned to fit within the classical receptive field. While maintaining gaze on a fixation point, the animals were instructed to respond to a speed increment within the cued surface. In a sensory condition, the monkeys were asked to respond to a luminance change of the fixation point. By systematically varying the overall pattern direction, tuning curves were measured with a constant relative angle of 120 degrees between the component directions. The activity profile across 90 MT units showed two peaks corresponding to the two stimulus configurations in which one of the directions moved in the neuron’s preferred direction. The profile can be well fit by the sum of two Gaussians, enabling a quantitative comparison of neuronal responses for the attended versus the sensory condition. The fitted tuning curves showed an average increase of 52% around the peak where the preferred direction was attended relative to the sensory condition. For the peak corresponding to the condition when the preferred direction was unattended, we observed an average suppression of 5%. Neither of the fitted individual Gaussians showed a change in tuning width. Our results, supported by preliminary numerical modeling, show that attending to one surface in a transparent motion stimulus causes a direction-dependent modulation of the population response in MT, representing the neural correlate of attentional allocation to an individual surface.Acknowledgments: The project was supported by the Volkswagen Foundation (grant I/79868) and by grant 01GQ0433 from the Federal Ministry of Education and Research to the Bernstein Center for Computational Neuroscience Goettingen. Conference: Bernstein Conference on Computational Neuroscience, Frankfurt am Main, Germany, 30 Sep - 2 Oct, 2009. Presentation Type: Poster Presentation Topic: Sensory processing Citation: Lochte A, Stephan V, Kozyrev V, Witt A and Treue S (2009). Attentional modulation of the tuning of neurons in area MT to the direction of transparent motion. Front. Comput. Neurosci. Conference Abstract: Bernstein Conference on Computational Neuroscience. doi: 10.3389/conf.neuro.10.2009.14.154 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 28 Aug 2009; Published Online: 28 Aug 2009. * Correspondence: Anja Lochte, German Primate Center, Göttingen, Germany, alochte@gwdg.de Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Anja Lochte Valeska Stephan Vladislav Kozyrev Annette Witt Stefan Treue Google Anja Lochte Valeska Stephan Vladislav Kozyrev Annette Witt Stefan Treue Google Scholar Anja Lochte Valeska Stephan Vladislav Kozyrev Annette Witt Stefan Treue PubMed Anja Lochte Valeska Stephan Vladislav Kozyrev Annette Witt Stefan Treue Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.
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