PRISMA Research Articles

Assessing Adherence to the PRISMA-DTA Guideline in Diagnostic Test Accuracy Systematic Reviews: A Five-Year Follow-up Analysis.

We evaluated reporting of diagnostic test accuracy (DTA) systematic reviews using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-DTA and PRISMA-DTA for abstracts. We searched MEDLINE for recent DTA systematic reviews (September 2023-Mar 2024) to achieve a sample size of 100. Analyses evaluated adherence to PRISMA-DTA (and abstracts), on a per-item basis. Association of reporting with journal, country, impact factor (IF), index-test type, subspecialty area, use of supplemental material, PRISMA citation, word count, and PRISMA adoption was evaluated. Comparison to the baseline evaluation from 2019 was done. Protocol: https://doi.org/10.17605/OSF.IO/P25TE. Overall adherence (n = 100) was 78% (20.3/26.0 items, SD = 2.0) for PRISMA-DTA and 52% (5.7/11.0 items, SD = 1.6) for abstracts. Infrequently reported items (<33% of studies): eligibility criteria, definitions for data extraction, synthesis of results, and characteristics of the included studies. Infrequently reported items in abstracts were characteristics of the included studies, strengths and limitations, and funding. Reporting completeness for full text was minimally higher in studies in higher IF journals [20.7 vs 19.8 items; 95% confidence interval (95%CI) (0.09; 1.77)], as well as studies that cited PRISMA [21.1 vs 20.1 items; 95%CI (0.04; 1.95)], or used supplemental material (20.7 vs 19.2 items; 95%CI (0.63; 2.35)]. Variability in reporting was not associated with author country, journal, abstract word count limitations, PRISMA adoption, structured abstracts, study design, subspecialty, open-access status, or index test. No association with word counts was observed among full text or abstracts. Compared to the baseline evaluation, reporting was improved for full texts [71% to 78%; 95%CI (1.18; 2.26)] but not for abstracts [50% to 52%; 95%CI (-0.20; 0.60)]. Compared to the baseline evaluation published in 2019, we observed modest improved adherence to PRISMA-DTA and no improvement in PRISMA-DTA for abstracts reporting.

Impact of intraoperative recurrent laryngeal nerve monitoring on minimally invasive esophagectomy outcomes for esophageal cancer: a meta-analysis of case-control studies.

Esophagectomy and lymphadenectomy for esophageal cancer carry an inherent risk of recurrent laryngeal nerve (RLN) injury. Intraoperative nerve monitoring (IONM) may help prevent RLN damage, though evidence on its effectiveness is still limited. This systematic review and meta-analysis (SRMA) evaluate the feasibility and efficacy of IONM during minimally invasive esophagectomy (MIE) for esophageal cancer. This SRMA followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Meta-Analysis of Observational Studies in Epidemiology (MOOSE) guidelines, with a registered protocol on PROSPERO (CRD42022367916). Two independent authors conducted a comprehensive literature search across multiple databases, screening studies on MIE for esophageal cancer using IONM. Case-control studies were included, focusing on the RLN palsy (RLNP) rate as the primary outcome. A total of 11 studies involving 1907 patients (IONM group: 752 patients; non-IONM group: 1155 patients) were included in the SRMA. IONM significantly reduced the incidence of RLNP (OR = 0.47, P < 0.001). Length of hospital stay (LOHS) and lower respiratory tract infection (LRTI) rates were significantly reduced with IONM use. No significant differences were observed in anastomotic leak, chylothorax, total number of lymph nodes dissected, operation time, aspiration rates, or intraoperative blood loss. The pooled sensitivity and specificity of IONM for detecting RLN injury were 83.3% and 81%, respectively. IONM during MIE significantly reduces the incidence of RLNP, postoperative LRTI, and shortens the LOHS, without adding operative risks. Further research is needed to evaluate its long-term survival benefits and cost-effectiveness.

Exploring the gut-brain axis in alzheimer’s disease treatment via probiotics: evidence from animal studies-a systematic review and meta-analysis

IntroductionAlzheimer’s disease (AD) is a prevalent neurodegenerative disorder in the elderly, causing cognitive impairment. Its pathogenesis is characterized by amyloid beta deposition, neurofibrillary tangles, and neuroinflammation. Recent research has identified the link between gut dysbiosis, an imbalance of intestinal microorganisms, to this pathogenesis via the gut-brain axis. This study aims to review the probiotics’ therapeutic effect, targeting the gut-brain axis, for AD treatment in animals.MethodsThe method utilized in this study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. Three reviewers searched articles through PubMed, Scopus, and Embase using advanced search strategy. Articles published between 2010 and 2023 that met the criteria were included.ResultsOf 2,273 articles, 21 animal studies measuring the effects of probiotics genera Lactobacillus and/or Bifidobacterium on AD via at least one of these four outcomes: AD pathology, cognitive function, neuroinflammation, and gut microbiota composition. The results demonstrated that probiotics could repair gut dysbiosis by decreasing pro-inflammatory bacteria and increasing anti-inflammatory bacteria. Repaired dysbiosis was found to be associated with less neuroinflammation as significant reductions in neuroinflammatory markers related to the pathogenesis of AD such as TNF-α (SMD = -2.08, P = 0.005), IL-6 (SMD = -2.98, P < 0.0005), and IL-1β (SMD = -2.49, P = 0.003) were observed. Reduced amyloid beta deposition (SMD = -1.17, P = 0.009) was reported, but reduction in tau hyperphosphorylation was found to be insignificant. For cognitive function, positive results were demonstrated for all three aspects of cognitive function including long-term memory (SMD = 2.55, P < 0.00001), short-term memory (SMD = 1.32, P = 0.003), and spatial recognition (SMD = -1.13, P < 0.00001).ConclusionsParticular formulas of probiotics showed potential effectiveness in AD therapies with demonstrated association with the gut-brain axis. Future studies are required to investigate strain-specific results and optimal dosages and regimens.

A scoping review on health literacy in parental educational practices: What do we know about it?

PurposeThis study aims to synthesize evidence on health literacy assessment in parental educational practices of parents/caregivers of newborns from 0 to 13 months old.Design/methodology/approachA scoping review. We synthesized qualitative and quantitative research according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). Database selection was based on specific content coverage of peer-reviewed articles in the biomedical and life sciences (PubMed) and health sciences and education (Scopus). We included articles complete original articles in English and/or Portuguese from peer-reviewed indexed journals whose reporting of evidence was in line with the objectives of this study: studies with parents and caregivers of newborns from 0 to 13 months old. Two independent reviewers extracted data and inconsistencies were resolved in a discussion between them and the third reviewer.FindingsA total of 345 articles were recruited, and 342 were excluded. The most studied age group was 2 months old. Regarding geographic location, most studies were carried out in the USA. All articles were published after the year 2010 and carried out only with fathers and mothers, excluding other caregivers (e.g. relatives and professionals).Research limitations/implications Only one instrument is focused on health literacy in parental educational practices.Originality/valueWe observe that this is a little-researched theme. All caregivers of young children face important barriers to understanding and implementing basic child health tasks (e.g. providing adequate nutrition, safety and medication).

Education for sustainability and physical education: a systematic scoping review

ABSTRACT Education for sustainability (EfS) in the school context is recognized scientifically and politically as fundamental for training citizens who are capable of transforming future society. Physical education (PE) represents a singular way to complement cognitive approaches by drawing on the bodily dimension and learning in action as well as affective and sensory aspects. Furthermore, relevant research could lead to the qualitative implementation of EfS in PE. Thus, the aim of this systematic scoping review was to summarize the results of related research into the implementation of EfS in PE and to identify avenues for future studies aimed at establishing EfS sequences within PE. A 5-step methodological framework, incorporating the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology, was used to carry out this scoping review, in which 30 studies were considered. The results showed that the research was current, was performed mainly in Europe, and frequently referred to the institutional framework of the Sustainable Development Goals. Additionally, the results highlighted that PE programs make few explicit references to the concept of sustainability or EfS; furthermore, PE teachers, while they may be inclined to implement EfS in PE, lack control of the concepts and training. Finally, the EfS learning sequences in PE have limitations regarding the definition and characteristics of effective EfS, particularly a lack of pluralism and holism. Recommendations for future research and for practical implementation were made, particularly with respect to PE teacher training, PE programs and EfS learning sequences in PE.

Agricultural Insurance Premium Determination Model for Risk Mitigation Based on Rainfall Index: Systematic Literature Review

Rainfall is significantly essential in the agricultural sector to increase productivity. However, rainfall instability serves as a potential source of risk, causing crop failure and negatively impacting the welfare of farmers. To mitigate this risk, rainfall index-based agricultural insurance offers financial protection to farmers. There is no information on how to set a reasonable premium in index-based agricultural insurance. Therefore, this research aimed to systematically explore a model for determining a rainfall index-based agricultural insurance premium, focusing on the methods used and their effectiveness in mitigating the risk of harvest failure in the agricultural sector. The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method and a bibliometric analysis were used to collect and analyze articles from Scopus, ScienceDirect, and Dimensions databases. The results showed that there were 15 articles on determining a rainfall index-based agricultural insurance premium, where 4 used the Black–Scholes method and 11 applied other main methods. Meanwhile, no articles applied the fractional Black–Scholes method in determining agricultural insurance premiums based on the rainfall index, providing new opportunities for further research. The results contributed to the development of a model for agricultural insurance premium determination that could generate more diverse and flexible premium estimates as a sustainable method to mitigate the risk of harvest failure. This research is expected to serve as a reference for developing rainfall index-based agricultural insurance in the future and contribute to the Government of the Agriculture Department’s policy formulation regarding insurance programs for farmers.

Factors influencing clinical supervision of undergraduate occupational therapy students during practice learning in the Global South: A rapid review

Background. Clinical practice learning is an important aspect of educating undergraduate occupational therapy (OT) students to understand the profession and for professional identity. Practice learning could be hampered by several factors including the lack of proficient clinical supervisors, coupled with a burgeoning number of students. To ensure the success of the programme, the expectations of lecturers and supervisors should be compatible. Objective. To investigate the factors influencing clinical supervision of undergraduate OT students during practice learning in the Global South. Methods. A rapid review of the literature was conducted between 2017 and 2022 with searches in EBSCOhost and PubMed databases. Mendeley Reference Manager was used as a tool for database storage, and the literature found was screened and documented according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement and guidelines. A hierarchy of evidence was formed using Tomlin and Borgetto’s (2011) research pyramid. Articles within the three most trustworthy and relevant levels of the qualitative hierarchy were appraised using the clinical appraisal skills programme (CASP) tool. Results. Five main themes emerged from a thematic analysis of 20 records: quality assurance; roles and relationships; hegemonies in and out of context; context of clinical practice; and teaching how. Conclusion. The key aspects influencing clinical supervision in undergraduate OT programmes are interconnected. The findings emphasise the importance of having a protocol, sequence of preparation and procedure, and training of personnel in informing quality of supervision. Quality individualised support for learners is best achieved when there is structure and proficient supervision.

An Integrative Review of Specialised Nursing Career Frameworks to Develop a Nursing Career Framework for Registered Nurses Working in Aged Care.

The aim of this study is to synthesise literature on specialised nursing career frameworks to inform the development of an aged care nursing career framework. An integrative review was conducted. The review followed Whittemore and Knafl's five-step integrative review method. To appraise the quality of the studies, the Quality Appraisal for Diverse Studies tool for peer-reviewed articles and the ACCODS (Authority, Accuracy, Coverage, Objectivity, Date, and Significance) checklist for grey literature were used. Data were extracted and synthesised using the constant comparison method. The electronic databases of CINAHL, Medline, PsycINFO and Google Scholar were searched to identify peer-reviewed articles and grey literature reporting on specialised nursing career frameworks for registered nurses. Eight studies were reviewed, and the findings were presented corresponding to each of the three research questions of the review. First, the research methods adopted to develop specialised nursing career frameworks were described based on the research design, stakeholder involvement and data collection methods. Second, the key elements of specialised nursing career frameworks were identified as career pathways, nursing competencies and roles and progression between the career levels. Third, the findings suggested that the key purposes for developing specialised nursing career frameworks are to improve professional development, recruitment and retention and to promote consistency and quality in nursing practice. The study highlights a significant gap in the evidence base of career frameworks for registered nurses in aged care, emphasising the need for future research. This review answered three research questions: methods for developing specialised nursing career frameworks, their key components and main purposes, providing insights to guide healthcare organisations and researchers. The findings indicate that career frameworks are primarily intended to promote knowledge and skills development and may also to bolster recruitment and retention rates, and support nurses' career advancement, but there is limited evidence on implementation, evaluation and sustainability. The findings will guide healthcare organisations and future researchers with methods and techniques to develop specialised nursing career frameworks. Implementing a specialised nursing career framework in aged care could enhance continuous professional development, recruitment, retention and career progression among nurses. Nursing career frameworks have been widely applied to address professional development and retention objectives. However, there is limited evidence available to formulate a career framework for registered nurses working in aged care. The review identified the research methods adopted to develop specialised nursing career frameworks along with the key elements of specialised nursing career frameworks. These findings will guide employers and future researchers in developing evidence-based aged-care nursing career frameworks. Additionally, the findings will guide registered nurses in using career frameworks as a tool to facilitate career advancement and competency development. Furthermore, the review recognised the key purposes for developing specialised nursing career frameworks, suggesting that the meaningful adoption of career frameworks could be utilised as a strategic approach for enhancing retention and workforce development of the aged care workforce. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was used for reporting. No patient or public contribution. The integrative review protocol was registered in the PROSPERO international prospective register of systematic reviews database (registration no: CRD42022354728).

Association between climate change and patient health outcomes: a mixed-methods systematic review

IntroductionClimate change poses significant threats to the environment, biodiversity, and socioeconomic stability worldwide. Its impact on human health, particularly within healthcare systems, is growing in concern. Nurses, as front-line healthcare workers, play a crucial role in addressing climate-related health risks. However, there is a gap in understanding nursing perspectives on climate change and its implications for patient health outcomes.AimTo synthesize empirical evidence on the association between climate change and patient health outcomes from a nursing perspective.MethodsA mixed-methods systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The search was carried out in January 2024 in six scientific databases including CINAHL, PubMed, Scopus, ProQuest, Web of Science, and OVID Nursing. Studies focusing on climate change and patient health outcomes from a nursing perspective were included. Data extraction, quality appraisal, and synthesis were performed systematically.ResultsThe systematic review included 18 studies of a mainly quantitative nature. Three main themes emerged as follows: Climate Healthcare Interplay; Future Nurses as Agents of Change; and Navigating Sustainability Challenges in Nursing. These themes highlighted nurses’ awareness of the interrelation between climate and health, the need for environmental education in nursing, and the challenges that hinder sustainable nursing practices.ConclusionThis review underscores the importance of integrating climate change topics into nursing education and fostering organizational support for sustainable nursing practices. Addressing these challenges is essential for nurses to mitigate the health risks posed by climate change effectively.

Unraveling the Link between Obesity and Tuberculosis: A Systematic Review of the Underlying Mechanisms

Background: Tuberculosis (TB) and obesity are significant global health concerns with potentially complex interactions. Obesity, through its effects on metabolism, inflammation, and the immune system, may influence TB susceptibility, progression, and treatment outcomes. This systematic review aims to analyze the published literature on the relationship between obesity and TB, focusing on the underlying mechanisms. Methods: A systematic search of PubMed, Science Direct, and Google Scholar was conducted for articles published in the last 10 years. The search strategy included keywords such as "tuberculosis," "TB," "obesity," and "BMI." Articles were selected using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) method. Results: The review identified 11 studies that met the inclusion criteria. The studies revealed a complex relationship between obesity and TB, with nutritional status, immunity, and diabetes mellitus (DM) playing key roles. Obesity can alter the immune response to TB, potentially increasing the risk of disease and affecting treatment efficacy. Conclusion: The relationship between obesity and TB is multifaceted, with obesity potentially influencing both disease susceptibility and outcomes. Further research is needed to fully elucidate the underlying mechanisms and to develop targeted interventions for individuals with both obesity and TB.

Human and animal brucellosis and risk factors for human infection in Ethiopia: a systematic review and meta-analysis (2015–2024)

Background and objectiveBrucellosis is a neglected zoonotic disease caused by Brucella species. Unlike most developed nations, the problem of brucellosis in Ethiopia remains a public and animal health concern. This study was conducted to determine the magnitude of brucellosis in animals (mainly cattle, sheep, goats, dogs and camels) and humans, and to identify the risk factors for human brucellosis.MethodologyThe Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed to conduct this systematic review and meta-analysis, which was performed from May 2024 to July 2024. Academic databases such as PubMed, ScienceDirect, Scopus, PubMed Central, Web of Science, and Google Scholar were searched to identify articles focusing on brucellosis in humans and animals in Ethiopia. Data extraction was performed according to predefined inclusion and exclusion criteria. The included articles were appraised using the appraisal tool for cross-sectional studies to assess study quality. Publication bias and small study effects were examined using funnel plot observation and Egger’s test, respectively. Statistical analysis was conducted using R software version 4.4.1.ResultsThirty-nine articles published between 2015 and 2024 were included in the final analysis from a total of 1,427 identified articles. The overall pooled seroprevalence of brucellosis was 5.0% (95% CI: 3.0, 6.0). The seroprevalence of brucellosis was higher in humans at 6.9% (95% CI: 4.9, 8.8) and lower in cattle at 3.5% (95% CI: 2.2, 4.7). There was high heterogeneity in the reports of brucellosis seroprevalence between studies (τ² = 0.0038, H² = 255.9, I² = 99.61%, Q-test = 1954.99, df = 56, p ≤ 0.001). Laboratory tests and study location were identified as factors contributing to potential sources of variation in the pooled seroprevalence. Drinking raw milk from aborted animals, touching aborted materials or fetuses, and occupation were among the risk factors for human brucellosis. No publication bias or small study effects were detected.ConclusionThe findings indicate that brucellosis continues to pose a significant zoonotic threat, particularly to humans, where the seroprevalence is notably higher than in animals. These results highlight the need for targeted public health interventions and greater awareness to reduce the incidence of brucellosis, especially among high-risk populations.

Prognostic significance of hemoglobin, albumin, lymphocyte and platelet score in solid tumors: a pooled study

ObjectiveThe high hemoglobin, albumin, lymphocyte, and platelet (HALP) score has been reported to be a good prognostic indicator for several malignancies. However, more evidence is needed before it can be introduced into clinical practice. Here, we systematically evaluated the predictive value of HALP for survival outcomes in patients with solid tumors.MethodsThis study was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Assessing the Methodological Quality of Systematic Reviews (AMSTAR) Guidelines. In March 2024, an electronic literature search was performed for articles regarding the prognostic role of HALP in solid tumors. Data from studies with reported risk ratios (HRs) and 95% confidence intervals (CIs) were pooled in a meta-analysis. Study bias was assessed using the QUIPS tool.ResultsOf the 729 articles reviewed, 45 cohorts including data from 17,049 patients with cancer were included in the pooled analysis. The pooled results demonstrated that elevated HALP score was significantly associated with favorable overall survival (HR = 0.60, 95% CI 0.54-0.67, p &amp;lt; 0.01), cancer-specific survival (HR = 0.53, 95% CI 0.44- 0.64, p &amp;lt; 0.01), progression-free survival (HR = 0.62, 95% CI 0.54-0.72, p &amp;lt; 0.01), recurrence-free survival (HR = 0.48, 95% CI 0.30-0.77, p &amp;lt; 0.01), and disease-free survival (HR = 0.72, 95% CI 0.57-0.82, p &amp;lt; 0.01). Subgroup analyses based on various confounding factors further revealed the consistent prognostic impact of HALP on overall survival in patients with solid tumors.ConclusionsOur findings suggest that high HALP is associated with better survival outcomes in patients. The HALP score is a potential prognostic biomarker in solid tumors, but it needs to be further studied whether it can improve the established prognostic model.

Influence of government policies on handwashing and vaccine uptake in Kenya, Uganda, and Tanzania to prevent and control COVID-19: a systematic review

IntroductionThe government's role in influencing policies related to Coronavirus disease 2019 (COVID-19) vaccine distribution and handwashing practices is essential in controlling the spread of severe acute respiratory syndrome coronavirus 2.MethodsThis study aimed to systematically review published studies to explore the influence of government policies on handwashing and vaccine uptake in Kenya, Uganda and Tanzania to prevent and control COVID-19. A comprehensive search strategy was applied across three databases, and eligibility was determined using strict inclusion and exclusion criteria. We reviewed 9 of 136 research papers following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines.ResultsThe findings revealed that the government has a role in influencing policies related to COVID-19 vaccine distribution and handwashing uptake. Employment of public health campaigns and communication strategies by the government in Uganda increased vaccine acceptance and hand hygiene uptake. Similarly, government efforts to make hand hygiene accessible increased the uptake of handwashing in Tanzania. In Kenya, government efforts to increase access to soap and clean water in informal settlements and markets resulted in increased adherence to handwashing practices. Further, government incentives such as cash increased vaccination rates while vaccination reminders combined with cash incentives increased childhood immunization coverage.DiscussionOverall, this review indicates that monitoring and enforcing compliance increases vaccine and handwashing uptake across the three countries. The effectiveness of government policies on handwashing and vaccine uptake is influenced by factors such as safety, efficacy and access to information, among others. Therefore, there is a need to address these factors for the successful implementation of these policies.Systematic review RegistrationPROSPERO ID CRD42023396319, https://www.crd.york.ac.uk/prospero/.

Unlocking Organizational Success: A Systematic Literature Review of Superintendent Selection Strategies, Core Competencies, and Emerging Technologies in the Construction Industry

An organization’s success depends on its ability to attract and retain skilled personnel. Superintendents play a critical role in overseeing project sites in the construction industry and can adapt to the increasingly complicated requirements of modern construction projects. This study examines traditional and modern personnel selection methods to determine effective tactics, essential competencies, and emerging trends regarding supervisory personnel. The research methodology follows the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework. First, this study examines traditional and modern selection methods used by organizations and engineering firms to provide a comprehensive overview of the topic and assist in selecting appropriate staff recruitment procedures. Second, the Web of Science, Scopus, and Google Scholar databases were reviewed to identify superintendent selection approaches and competencies, over the period January 2000 to September 2024. A total of 22 relevant papers were analyzed. Superintendent selection processes included questionnaires (57%), interviews (26%), literature reviews (14%), and data-driven AI tools (3%). Forty competency criteria were identified, with the top five being knowledge, communication skills, leadership, health and safety expertise, and commitment. As a result, novel approaches employing Industry 4.0 technologies, including virtual reality (VR), wearable sensing devices (WSDs), natural language processing (NLP), blockchain, and computer vision, are recommended. These findings support a better understanding of how best to identify the most qualified supervisory personnel and provides enhanced methods for evaluating job applicants.

Magnitude and associated factors of postpartum family planning uptake among postpartum women in Ethiopia: an umbrella review

BackgroundThe World Health Organization indicates that despite advancements, the rates of maternal and neonatal mortality and morbidity during the postpartum period continue to be alarmingly high. Furthermore, untapped opportunities to enhance maternal health and promote effective newborn care, including family planning services, have not been fully leveraged. Earlier meta-analyses and systematic reviews have addressed this subject; however, a thorough evidence synthesis has not been provided. Therefore, the objective of this study was to compile the existing systematic reviews (SRs) concerning postpartum family planning uptake among postpartum women in Ethiopia.MethodThis review used an umbrella review method, incorporating numerous systematic reviews. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the Meta-analysis of Observational Studies guideline (MOOSE). A comprehensive literature review was conducted across prominent four electronic databases (including MEDLINE/PubMed, Cochrane, Web of Science and Science Direct) from June 15, to July 15, 2024. This review encompassed investigations carried out within the uptake of family planning among post-partum women and its determinants in Ethiopia were the primary outcome. A set of inclusion criteria was established to identify all pertinent systematic reviews, including studies, with no restrictions on data collection and publication year. The quality of the methods was evaluated using the Assessment of Multiple Systematic Reviews tool, (AMSTAR) tool. Statistical analysis was conducted using STATA version 17 software, and the 95% confidence interval was utilized to establish statistical significance. I-squared statistics were employed to evaluate the heterogeneity of the studies by using a random-effects meta-analysis model.ResultsThe umbrella review includes five studies with a total of 44,276 postpartum women. The pooled prevalence of postpartum family planning utilization was 36.41% (95% CI: 24.78, 48.03). Family planning counseling (AOR: 4.12, 95% CI: 2.89, 4.71), couple discussion (AOR: 3.06, 95% CI: 1.42, 5.60), and postnatal follow-up (AOR: 3.48, 95% CI: 2.60, 4.83) were significantly associated with postpartum family planning uptake.ConclusionThe result (36.4%) which mentioned in the conclusion part will be removed and the whole text will be replaced by: The study results indicate that the adoption of postpartum family planning in Ethiopia requires focused intervention. This can be achieved by identifying and enhancing community frameworks to involve men in reproductive health initiatives and by providing comprehensive family planning information and services during postnatal care. Addressing the aforementioned factors is crucial to mitigate the risks associated with unintended pregnancies and to manage the swift increase in population.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024568435, PROSPERO (CRD42024568435).

Interventions to improve pharmacists’ competency in chronic disease management: a systematic review of randomized controlled trials

IntroductionEffective chronic disease management (CDM) is vital for addressing chronic disease challenges. Given the importance of ensuring pharmacists’ competence in CDM, interventions targeting knowledge, skills, and attitudes are essential. Therefore, a comprehensive and up-to-date study is needed to analyze these interventions’ effect and potential development. Categorizing the interventions based on the Effective Practice and Organization of Care (EPOC) taxonomy is essential for better informing policymakers. The objectives of this systematic review were to identify interventions to improve pharmacists’ competency in chronic disease management based on the EPOC taxonomy and summarize their effectiveness.MethodsFollowing methods in the Cochrane Handbook, a systematic search was conducted up to April 2024 on MEDLINE and Scopus. The inclusion criteria were an intervention study with a randomized controlled trial (RCT) design published in English, targeting pharmacists, and measuring knowledge, skills, and attitudes in aspects of CDM. The risk of bias was assessed using Cochrane’s RoB 2 tool for either randomized or cluster-randomized trials. Findings are reported narratively and align with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.ResultsWe included 11 RCT studies that focused on various aspects of CDM among community and hospital pharmacists. Implementation strategies and combined implementation strategies–delivery arrangements interventions were identified. Six implementation strategies interventions consistently yielded effective results, with scores ranging from 0.99 to 9.17 (p < 0.05). However, the other two implementation strategies interventions reported mixed results, with no significant improvements in knowledge or skills. Two implementation strategies-delivery arrangements interventions showed improvements, with score differences ranging from 4.5% (95% CI: 1.6%-7.4%) to 30% (95% CI: 29%-40%). Conversely, one implementation strategies-delivery arrangements intervention showed no significant improvement. The risk of bias assessment revealed varying levels of bias across the studies.ConclusionsImplementation strategies and combined implementation strategies–delivery arrangements interventions improved pharmacists' competency in CDM. Most interventions consistently resulted in significant improvements in pharmacists' knowledge, skills, and attitudes. These findings underscore the potential of tailored, competency-based interventions to improve pharmacist competencies in CDM. Policymakers can use these insights to create guidelines and policies that promote ongoing professional development for pharmacists.

Multi-criteria decision-making for solving transport sustainability issues: an overview

With the recognition of the impact of the transport sector on climate change and human health, decision-makers are under the pressure to shape the transport sector in a more sustainable way, considering more sustainable options and technologies. Besides that, it is also important to ensure such aspects as affordability, security, reliability and convenience of transport services and the effective functioning of the whole system. Therefore, transport-related policy actions require not only an economic point of view, but also environmental and social actions. The article aims to overview the application of Multi-Criteria Decision-Making (MCDM) techniques for solving sustainability issues in the transport sector and to provide the main insights for methods and sustainability criteria selection. The Search, Appraisal, Synthesis and Analysis (SALSA) framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement were applied as the basis for the research. The detailed content analysis of studies is arranged according to the application areas and the methods applied. In order to increase the applicability of the performed analysis and to simplify the decision-making for further studies, the thematic areas for criteria selection are proposed, the most popular MCDM techniques alongside their advantages and disadvantages are briefly discussed.

The Algorithmic Divide: A Systematic Review on AI-Driven Racial Disparities in Healthcare.

As artificial intelligence (AI) continues to permeate various sectors, concerns about disparities arising from its deployment have surfaced. AI's effectiveness correlates not only with the algorithm's quality but also with its training data's integrity. This systematic review investigates the racial disparities perpetuated by AI systems across diverse medical domains and the implications of deploying them, particularly in healthcare. Six electronic databases (PubMed, Scopus, IEEE, Google Scholar, EMBASE, and Cochrane) were systematically searched on October 3, 2023. Inclusion criteria were peer-reviewed articles in English from 2013 to 2023 that examined instances of racial bias perpetuated by AI in healthcare. Studies conducted outside of healthcare settings or that addressed biases other than racial, as well as letters, opinions were excluded. The risk of bias was identified using CASP criteria for reviews and the Modified Newcastle Scale for observational studies. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, 1272 articles were initially identified, from which 26 met eligibility criteria. Four articles were identified via snowballing, resulting in 30 articles in the analysis. Studies indicate a significant association between AI utilization and the exacerbation of racial disparities, especially in minority populations, including Blacks and Hispanics. Biased data, algorithm design, unfair deployment of algorithms, and historic/systemic inequities were identified as the causes. Study limitations stem from heterogeneity impeding broad comparisons and the preclusion of meta-analysis. To address racial disparities in healthcare outcomes, enhanced ethical considerations and regulatory frameworks are needed in AI healthcare applications. Comprehensive bias detection tools and mitigation strategies, coupled with active supervision by physicians, are essential to ensure AI becomes a tool for reducing racial disparities in healthcare outcomes.

Role of memantine in adult migraine: a systematic review and network meta-analysis to compare memantine with existing migraine preventive medications

BackgroundWhile memantine has been considered a promising drug for migraine prevention, no conclusive evidence exists comparing its efficacy with other migraine-preventive medications. This network meta-analysis (NMA) aimed to access the effectiveness and acceptability of memantine and other guideline-recommended prophylactic agents for migraine.MethodsWe searched the Cochrane Register of Controlled Trials, Embase, PubMed, and ClinicalTrials databases from their inception to 1 June 2024. Randomized placebo-controlled trials (RCTs) examining the pharmacological prevention of adult migraine patients were included. The primary efficacy outcome was the change in migraine days, and the primary safety outcome was withdrawal due to adverse events. Secondary outcomes included 50% response rates and frequency of any adverse events. The analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.ResultsThirty-eight RCTs, including a total of 13,223 participants, were analyzed. Our analysis showed that memantine demonstrated the second-largest reduction in migraine days [standardized mean difference (SMD): −0.83; 95% confidence interval (CI): −1.26, −0.41 compared with placebo] and the highest 50% response rates [odds ratio (OR): 5.58, 95% CI: 1.31 to 23.69] in all studied interventions. Moreover, among all interventions, memantine appeared to show the lowest dropout rate and moderate frequency of adverse events. However, its confidence intervals contained null values.ConclusionThis study provides prioritisation evidence for memantine in migraine prevention, as memantine can significantly decrease the frequency of migraine attacks, improves response rates, and fair acceptability. These beneficial effects were not inferior to currently recommended pharmacological regimens. However, due to the lack of long-term efficacy and safety data, as well as few direct comparisons with active control agents, the estimates of memantine may be overly optimistic. Clinicians should interpret the findings of current NMA cautiously and apply them in a relatively conservative manner.

Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis.

The present meta-analysis compared the efficacy of intra-articular hyaluronic acid (HA) injections in patients with early to mild knee osteoarthritis (OA) (Kellgren Lawrence I-II) versus other commonly injected biologically active compounds using patient-reported outcome measures (PROMs). The outcomes of interest were the visual analogue scale (VAS) and the Western Ontario McMaster Osteo-Arthritis Index (WOMAC) scores. This study was conducted according to the 2020 PRISMA statement. In April 2024, PubMed, Web of Science, Google Scholar, and Embase were accessed without time constraints. All the randomised controlled trials (RCTs) investigating the efficacy of intra-articular HA injections in the early stages of knee OA were accessed. Data concerning the VAS, WOMAC, and related subscales were collected at baseline and the last follow-up. Only studies clearly stated the degrees of advancement of OA using the Kellgren-Lawrence scoring system were used. The literature search resulted in four RCTs (390 patients). The mean length of the last follow-up was 7.5 ± 3.0months. 72.3% (282 of 390) of the patients were women. The mean age of the patients was 58.1 ± 3.2years, and the mean BMI was 27.3 ± 3.2kg/m2. At the last follow-up, no difference was found between HA and the control group in VAS, WOMAC, and related subscales. In patients with early to mild knee osteoarthritis, the current level of evidence suggests that intra-articular injections using HA performed similarly to other biologically active compounds commonly injected in the knee joint for a minimum of three months. Level I, meta-analysis.