Predictors Of Anxiety In Patients Research Articles

Burden of Anxiety, Depression and Perceived Stress in Patients with Inflammatory Bowel Disease: A Cohort Study from North India.

Patients with Inflammatory bowel disease (IBD) are susceptible to psychiatric co-morbidities. We aimed to ascertain the burden of anxiety, depression, and perceived stress in patients with IBD from north India. Consenting adult patients with an established diagnosis of IBD were enrolled. The enrolled patients filled the Hospital Anxiety and Depression Scale (HADS) and Perceived Stress Scale (PSS) questionnaires. The patient and disease characteristics were analyzed to determine the correlations and predictors of psychiatric comorbidities. A total of 318 patients (255 UC, 63 CD; mean age 40.13 ± 12.06years, 168 [52.8%] males; mean partial Mayo score 2.10 ± 2.35; and mean HBI 2.77 ± 2.13) were enrolled. The prevalence of anxiety, depression and moderate to high perceived stress was 14%, 12%, and 41%, respectively. Females had higher mean perceived stress, anxiety and depression scores compared to males. The partial Mayo score (PMS) correlated poorly with anxiety (ρ = 0.083, p = 0.187), depression (ρ = 0.123, p = 0.49) and perceived stress (ρ = 0.169; p = 0.007). The Harvey Bradshaw index (HBI) correlated fairly with anxiety (ρ = 0.336, p = 0.007) and poorly with depression (ρ = 0.287, p = 0.022) and perceived stress (ρ = 0.20; p = 0.117). Younger age (OR 0.93, 95% CI 0.90-0.97; p = 0.001) and hand-grip strength (OR 4.63, 95% CI 1.88-11.42; p = 0.001) predicted anxiety in patients with UC while rural area of residence (OR 4.75, 95% CI 1.03-21.98; p = 0.046) and HBI (OR 1.60, 95% CI 1.12-2.29; p = 0.009) were significant predictors of anxiety in patients with CD. Psychiatric comorbidities are common in patients with IBD, with higher prevalence in females. Young adults with UC and sarcopenia; and individuals with active CD living in rural areas are at an increased risk of anxiety.

P382 The burden of anxiety, depression and perceived stress in patients with inflammatory bowel disease: a cohort study from north India

Abstract Background Patients with Inflammatory bowel disease (IBD) are susceptible to psychiatric co-morbidities. We aimed to ascertain the burden of anxiety, depression, and perceived stress in patients with IBD from north India. Methods Consenting adult patients with an established diagnosis of IBD were enrolled. The enrolled patients filled the Hospital Anxiety and Depression Scale (HADS) and Perceived Stress Scale (PSS) questionnaires. The patient and disease characteristics were analyzed to determine the correlations and predictors of psychiatric comorbidities. Spearman’s rho (ρ) was used for assessment of correlation between disease attributes and psychological disorders. Results A total of 318 patients (255 UC, 63 CD; mean age 40.13±12.06 years, 168 [52.8%] males; mean partial Mayo score 2.10±2.35; and mean HBI 2.77±2.13) were enrolled. The prevalence of anxiety, depression and moderate to high perceived stress was 14.15%, 12.57%, and 41% respectively. Females had higher mean perceived stress, anxiety and depression scores compared to males. The partial Mayo score (PMS) correlated poorly with anxiety (ρ=0.083, p=0.187), depression (ρ=0.123, p=0.49) and perceived stress (ρ=0.169; p=0.007). The Harvey Bradshaw index (HBI) correlated fairly with anxiety (ρ=0.336, p=0.007) and poorly with depression (ρ= 0.287, p=0.022) and perceived stress (ρ=0.20; p=0.117). Younger age (OR 0.93, 95% CI 0.90-0.97; p=0.001) and hand grip strength (OR 4.63, 95% CI 1.88-11.42; p=0.001) predicted anxiety in patients with UC while rural area of residence (OR 4.75, 95% CI 1.03-21.98; p=0.046) and HBI (OR 1.60, 95% CI 1.12-2.29; p=0.009) were significant predictors of anxiety in patients with CD. Conclusion Psychiatric comorbidities are common in patients with IBD, with higher prevalence in females. Young adults with UC and sarcopenia; and individuals with active CD living in rural areas are at an increased risk of anxiety.

Neuropathic pain, cognitive fusion, and alexithymia in patients with multiple sclerosis: Cross-sectional evidence for an explanatory model of anxiety symptoms.

This preliminary study explored a novel model for anxiety symptoms in PwMS, including neuropathic pain (NeP), cognitive fusion (CF), experiential avoidance (EA), and alexithymia as explanatory factors. This cross-sectional study integrated two independent convenience samples: 107 PwMS recruited from the Portuguese Society for Multiple Sclerosis and 97 age- and gender-matched participants without the MS diagnosis (no-MS sample) recruited from the Portuguese general population. Self-report questionnaires that measured the constructs included in the model were administered to both groups. PwMS showed significantly higher values regarding anxiety symptoms and their explanatory variables (NeP, CF, EA, alexithymia) in comparison to non-MS participants. In the MS sample, no correlations were found between anxiety symptoms and sociodemographic and clinical characteristics. NeP, CF, and alexithymia showed significant correlations with anxiety symptoms and significantly explained this symptomatology in simple linear regression models. Thus, these variables were retained in the multiple linear regression model and emerged as significant regressors that together explained 38% of the variance in anxious symptomatology in PwMS. This preliminary study provides novel evidence on NeP and some maladaptive emotion regulation strategies related to EA/psychological inflexibility, as vulnerability to anxiety in PwMS can be considerably increased by CF and alexithymia. Clinical implications were discussed.

Pain, Fatigue, Nausea, and Vomiting as the Predictors of Anxiety in Patients Undergoing Hematopoietic Stem Cell Transplantation: A Prospective Cohort Study

The primary outcome was to assess the correlation between anxiety and pain, fatigue, nausea, and vomiting. The secondary outcome was to determine the predictive roles of pain, fatigue, nausea, and vomiting in anxiety among patients undergoing Hematopoietic Stem Cell Transplantation (HSCT). The present prospective cohort study was conducted on 200 patients treated by HSCT referred to the centers affiliated to Shiraz University of Medical Sciences. The data were collected using Spielberger Anxiety Questionnaire, Numerical Pain Scale, Brief Fatigue Inventory, and Rhodes Nausea and Vomiting Index. The data were analyzed using Spearman’s test and multiple regression analysis. The means of state anxiety, trait anxiety, pain, fatigue, and nausea, vomiting, and retching were 41.67 (SD = 9.71), 43.78 (SD = 9.00), 3.79 (SD = 2.79), 4.23 (SD = 2.48), and 6.31 (SD = 7.53), respectively. The results showed that the participants with higher pain and fatigue scores had higher anxiety levels. Those with more nausea and vomiting had higher anxiety levels, as well. This indicated that fatigue, pain, severity and frequency of nausea, and type of HSCT were the predictors of trait anxiety. The results also showed the predictor role of pain, fatigue, and type of HSCT in state anxiety. The findings revealed a correlation between anxiety and pain, fatigue, nausea, and vomiting among the HSCT patients. The results also showed fatigue and pain as the predictors of anxiety among these patients. Yet, future studies are recommended to determine the other factors contributing to anxiety amongst HSCT patients.

Gender, Age, previous Myocardial Infarction, and Personality as Predictors of Anxiety in Patients after Myocardial Infarction

Objectives: The first research objective was to study the prevalence of anxiety in patients after myocardial infarction; next objective was to investigate demographic and personality predictors of anxiety. Methods: 100 hospitalized patients after myocardial infarction were studied. The Mini IPIP tool was used for the evaluation of personality characteristics and HADS-A scale was used for the evaluation of anxiety. Multiple regression was used as an analytical framework. Results: The prevalence of significant anxiety among patients after myocardial infarction was high, almost one half of patients reported abnormal anxiety symptoms. Female gender, higher age, higher neuroticism and lower conscientiousness explain 66% of the variability of anxiety. Personality traits of extraversion, openness, agreeableness and previous myocardial infarctions do not show as significant predictors. Conclusion: The prevalence of anxiety in the group of patients after myocardial infarction is high. Knowing predictors of anxiety is important for better provision of care.

Preprocedural Anxiety in the Transradial Cardiac Catheterization Era.

Transradial cardiac catheterization is increasingly being used for the management of coronary artery disease given the low risk of procedural discomfort and complications with this approach. However, the evidence relating to preprocedural anxiety levels in these patients is scarce. The aim of this study was to evaluate the anxiety levels and the predictors of anxiety in patients undergoing transradial cardiac catheterization procedures. Data were collected using a self-administered survey. Anxiety was measured using the Spielberg's State-Trait Anxiety Inventory questionnaire. Multiple regression analysis was used to identify whether gender, age, family history of heart disease, smoking status, history of depression, and trait anxiety scores were predictors of preprocedural anxiety. A total of 198 patients participated in this study. More than half of the patients (53.5%) were classified as having a high state anxiety level. The mean (SD) preprocedural trait and state anxiety scores were 35.34 (9.8) and 36.43 (11.4), respectively. Female patients, those younger than 65 years, current smokers, and those with a family history of heart disease, a history of depression, and a history of anxiety had significantly higher anxiety scores. Having high trait anxiety scores was the only predictor of preprocedural anxiety. Although the transradial approach has a low procedural risk and causes less discomfort to the patient, anxiety persists in more than 50% of patients, with trait anxiety being the best predictor. Nurses should therefore try to decrease anxiety levels in the preprocedural phase to minimize postprocedural adverse outcomes in this group of patients.

Level and predictors of anxiety in patients undergoing diagnostic bronchoscopy.

AIMS:Flexible bronchoscopy is a common procedure performed in pulmonary medicine, critical care, and thoracic surgery. In this study, we aimed to assess the prevalence and predictors of anxiety in patients undergoing diagnostic bronchoscopy.METHODS:This is a prospective study conducted at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. All patients undergoing diagnostic bronchoscopy filled the State-Trait Anxiety Inventory questionnaire before the procedure. Bronchoscopy was performed either through the mouth or the nose, based on the bronchoscopist preference. Lidocaine (1%–2%) spray was used for administering topical anesthesia. Results were collected, and statistical analysis was performed using t-test to measure statistically significant (P < 0.05).RESULTS:A total of 117 patients participated in this study. High anxiety score was found in 45% of the patients. Older patients significantly showed higher anxiety score than younger patients (53 years vs. 46 years, P = 0.034). Similarly, patients with higher body mass index (BMI) showed a statistically significant increase in anxiety score (28 vs. 25, P = 0.041). Premedication with pethidine significantly reduced the anxiety levels (26.9% vs. 73.1%, P = 0.031). Logistic regression demonstrated that old age and outpatient settings were significant predictors of higher anxiety scores.CONCLUSION:Diagnostic bronchoscopy can cause high anxiety in many patients. Prebronchoscopy anxiety assessment can help bronchoscopists to anticipate the anxiety levels of patients, and then further use it to tailor sedation requirements. Special attention should be given to older patients, patients with high BMI, and the ones undergoing bronchoscopy in outpatient settings.

Predictors of anxiety in patients with Alzheimer's disease.

Depression and AnxietyVolume 11, Issue 1 p. 38-42 Brief Report Predictors of anxiety in patients with Alzheimer's disease Raymond L. Ownby M.D.,Ph.D., Corresponding Author Raymond L. Ownby M.D.,Ph.D. rownby@ibm.net Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center and the University of Miami School of Medicine, Miami, Florida Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Miami, FloridaDepartment of Psychiatry and Behavioral Sciences, Mount Sinai Medical Center, 4300 Alton Road, MRI Building, 2nd Floor, Miami Beach, FL 33140Search for more papers by this authorDylan G. Harwood M.A., Dylan G. Harwood M.A. Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center and the University of Miami School of Medicine, Miami, Florida Department of Educational and Psychological Studies, University of Miami, Miami, FloridaSearch for more papers by this authorWarren W. Barker M.A.,M.S., Warren W. Barker M.A.,M.S. Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center and the University of Miami School of Medicine, Miami, FloridaSearch for more papers by this authorRanjan Duara M.D., Ranjan Duara M.D. Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center and the University of Miami School of Medicine, Miami, Florida Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Miami, Florida Departments of Medicine and Neurology, University of Miami School of Medicine, Miami, FloridaSearch for more papers by this author Raymond L. Ownby M.D.,Ph.D., Corresponding Author Raymond L. Ownby M.D.,Ph.D. rownby@ibm.net Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center and the University of Miami School of Medicine, Miami, Florida Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Miami, FloridaDepartment of Psychiatry and Behavioral Sciences, Mount Sinai Medical Center, 4300 Alton Road, MRI Building, 2nd Floor, Miami Beach, FL 33140Search for more papers by this authorDylan G. Harwood M.A., Dylan G. Harwood M.A. Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center and the University of Miami School of Medicine, Miami, Florida Department of Educational and Psychological Studies, University of Miami, Miami, FloridaSearch for more papers by this authorWarren W. Barker M.A.,M.S., Warren W. Barker M.A.,M.S. Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center and the University of Miami School of Medicine, Miami, FloridaSearch for more papers by this authorRanjan Duara M.D., Ranjan Duara M.D. Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center and the University of Miami School of Medicine, Miami, Florida Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Miami, Florida Departments of Medicine and Neurology, University of Miami School of Medicine, Miami, FloridaSearch for more papers by this author First published: 22 February 2000 https://doi.org/10.1002/(SICI)1520-6394(2000)11:1<38::AID-DA6>3.0.CO;2-ECitations: 23AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume11, Issue12000Pages 38-42 RelatedInformation