Caorso Nuclear Power Plant area is extremely representative of the central Po River territorial system, which is characterized by a profound conflict between impactful infrastructures and semi-natural environments with high ecosystem value. In this context, the decommissioning of the Power Plant transcends the local scale, triggering reflections about the resurgence of the nature and the need to rethink our lifestyles and how they impact the planet.Starting from the outcomes of LOL2023 International Workshop by Politecnico di Milano, the article proposes methodological reasoning to investigate the potential that this decommissioning phase opens. In particular, the text investigates three design principles that can potentially be used to transform the Power Plant’s ‘dying’ energy landscape into an inviting habitat for a wide community of living beings, without, however, scarifying the spatial quality lent by design.