Abstract New alloy materials developed to meet the increasing technological needs of people come into our lives with some difficulties in terms of machinability. New cooling and lubrication techniques have been developed to facilitate the workability of such difficult-to-process materials and protect the world ecologically and the quality of the produced product. The workpiece used in this study, Vanadis 10 SuperClean, is a high vanadium alloyed powder metallurgy tool steel offering a unique combination of excellent abrasive wear resistance in combination with a good chipping resistance. The present study investigated the effects of dry, cryo, and CryoMQL cutting conditions on cutting tool vibration amplitude, cutting temperature, surface roughness, tool wear, and tool life in turning of Vanadis 10 tool steel used in the automotive industry. The experiments were performed using TiCN/Al2O3/TiN coated cemented carbide tools and cutting parameters as the constant depth of cut (1 mm), feed rates (0.08, 0.1, 0.12 mm rev−1), and cutting speeds (80, 100, 120 m min−1). The results obtained from experiments showed that spraying liquid nitrogen into the cutting zone provided significant improvements on cutting temperature, tool wear, cutting tool vibration amplitude, and surface roughness. The best results in terms of all output were achieved in the CryoMQL cutting environment. CryoMQL environment has reduced surface roughness up to 65.03 %, flank wear 56.99 %, cutting temperature 32.77 %, and cutting tool vibration amplitude up to 42.76 % compared to dry machining.