The study investigated the awareness and perceived efficiency of Tagiri (Lagenaria breviflorus) among poultry farmers in Ido Local Government Area, Oyo State, Nigeria using data obtained from eighty well-structured questionnaires. The result showed that 90.0% of the respondents were male, 60% had primary and secondary education and 68.8% practice intensive system of management. The result also revealed that 50.0% are aware of the antimicrobial property used to treat and control bacterial infection, 46.6% are aware that it has antibacterial property which suppresses the growth of bacterial and their ability to reproduce. It also revealed that 93.1% of the respondents used Lagenaria breviflorus for medicinal purpose. In conclusion, it was examined that majority of the farmers used Tagiri in treating poultry diseases. It was therefore recommended that the extension agents should further put more effort by sensitizing the farmers on the benefits of this medicinal plant for healthy growth in poultry management and since it is effective in treating poultry disease, it should also be adopted for other livestock.