Potential Cycling Research Articles

Steered Bubble: An Interposer-based Deadlock Recovery Algorithm for Multi-chiplet Systems

Dividing a single System-on-Chip (SoC) into multiple chiplets and integrating them via an interposer can achieve an optimal balance between continuous transistor integration and monetary cost. However, potential deadlock may arise between the chiplets and the interposer. This deadlock can be avoided by applying turn restriction or injection control on the boundary routers, at the cost of additional latency and sub-optimal performance. Compared to deadlock avoidance, deadlock recovery exerts less impact on network performance. Nevertheless, accurate and timely deadlock detection, along with efficient deadlock recovery, continues to pose significant challenges. Additionally, modularity is a specific concern, which involves integrating chiplets of various functions, sizes, manufacturing processes, and so on. Minimizing the negative impact of deadlock resolution while maximizing modularity is crucial for achieving the benefit of chiplets. This paper proposes a modular deadlock detection strategy, Up-Down, which monitors both the upward and downward directions of vertical channels, facilitating information exchange through the congestion-sense network. When a pair of blocked upward and downward vertical channels is detected simultaneously, it is considered that an inter-chiplet deadlock has occurred. This significantly enhances the accuracy of deadlock detection by two orders of magnitude compared to time-out deadlock detection. Furthermore, this paper introduces Steered Bubble, a low-cost deadlock recovery algorithm. It does so by injecting bubbles into potential deadlock cycles identified by Up-Down. These bubbles follow preset paths, ensuring efficient deadlock recovery. Experimental results indicate that the Steered Bubble results in an average performance enhancement of \(1\% \sim 10\% \) during full-system simulations, with an area overhead of less than 2%.

Time-course assessment of oral intake function and its impact on end-of-life in older individuals over 90 years with frailty.

The study investigates end-of-life trajectories, focusing on the degree of oral intake function in older individuals with frailty aged over 90 years. This retrospective observational study examined individuals aged 90 years and older who passed away at a long-term chronic care hospital and related facilities in Japan. We assessed their Clinical Frailty Scale (CFS) and Function Oral Intake Scale (FOIS), categorizing them into two groups-"preserved CFS" (CFS score ≤7) and "poor CFS" (CFS score ≥8)-considering evaluations conducted 6 months before death. We examined the transitional progression of their CFS and FOIS scores, along with a time-course assessment of low FOIS scores (≤3) in each group at various intervals. Among 66 cases, 38 were in the preserved CFS group, and 28 were in the poor CFS group. The CFS and FOIS scores of the preserved CFS group declined rapidly towards the end-of-life, with approximately half experiencing significant declines within 3 months. In contrast, both the CFS and the FOIS scores of the poor CFS group declined gradually within 6 months. The percentage of low FOIS score (≤3) was lower at 12 and 6 months than at 1 month prior to death in the preserved CFS group. The end-of-life trajectories in older individuals with frailty aged over 90 years were heterogeneous. Clinicians should carefully monitor the degree of frailty and changes in food intake as crucial indications of the end-of-life phase, providing optimal support to manage potential vicious cycles. Geriatr Gerontol Int 2024; ••: ••-••.

Effect of Use Hormonal Progestin Birth Control on Length of Use, Incidence of Menstrual Cycle Disorders in Birth Control Acceptors in Muara Enim District in 2024

This study aims to determine the effect of progestin hormonal contraceptive use on the duration of use and the incidence of menstrual cycle disorders among contraceptive acceptors in Muara Enim District in 2024. The method used is a correlational design with a cross-sectional approach. The population in this study consisted of all hormonal contraceptive acceptors in Muara Enim District, with a sample size of 853 people, determined using G Power software. Data analysis was conducted using the Spearman’s rho test. The statistical test results showed a p-value of 0.000 (<0.05), indicating a significant relationship between hormonal contraceptive use and menstrual cycle disorders. A correlation coefficient of 0.28 indicates a fairly strong and positive relationship. Furthermore, there is a relationship between the duration of hormonal contraceptive use and menstrual cycle disorders, with a p-value of 0.000 (<0.05) and a correlation coefficient of 0.39, suggesting a moderate and positive relationship in the same direction. These findings are expected to provide valuable information for healthcare providers to offer more accurate recommendations regarding potential menstrual cycle disorders in progestin hormonal contraceptive users, enabling patients to better understand the possible risks associated with this contraceptive method.

Archaenybelina gen. nov. (Trypanorhyncha Diesing, 1863) from Mobula thurstoni (Lloyd, 1908), including the description of two new species from Bali, Indonesia

Two specimens of Mobula thurstoni (Lloyd, 1908) were obtained from fishermen of Karangasem, Indonesia, and studied for trypanorhynch cestodes. Archaenybelina gen. nov., including two new species A. pseudotetrabothrialis sp. nov. and A. mimicricestus sp. nov., were recorded from the stomach and spiral valve and analysed for details of scolex and segment morphology, and surface ultrastructure. The new genus is characterized by 4 asymmetrical bothria separated by deep posterior notches, the presence of tegumental grooves, a homeoacanthous heteromorphous armature and a unique segment morphology. Both species can be separated by different hook sizes, basal hook rows and distribution of bothrial microtriches. Scolex surface ultrastructure shows hamulate spinitriches on bothria, lineate spinitriches along bothrial margins, and papilliform filitriches on the scolex peduncle. Similar microtriches have been reported from the bothrial margins of the Tentaculariidae. Tegumental grooves with a probably secretory function based on histology are present on the posterior bothrial margin. A collar of uncinate microtriches appear at the outer surface, separated from an internal bulbous structure, clearly distinguish this organ from the ciliated pits of the Otobothriidae. Based on four bothria, appearing not entirely separated at the anterior part of the scolex that indicates an originally bifossate state, a homeoacanthous heteromorphous armature, tegumental grooves, the absence of prebulbar organs and the presence of muscular rings, we assign the new genus into the Paranybeliniidae Schmidt, 1970. Describing first details of the segment morphology add to the family diagnosis in the most recent classification. The unique morphology of the new genus including its potential life cycle that involves oceanic devil rays as final and euphausiid crustaceans as second intermediate hosts are discussed.

Guidance for targeted degradation analysis of OER kinetics of low-loading iridium-based catalysts in PEM water electrolysis cells

This paper critically evaluates three methods for determining metrics of the oxygen evolution reaction (OER) describing the performance and stability of low-loading iridium-based anode catalyst layers (CLs) in proton exchange membrane water electrolysis (PEMWE) cells. The methods applied are OER mass activity, voltage breakdown analysis (VBA), and constant Tafel slope VBA (CT-VBA). They are used to assess the OER metrics as a function of anode CL configurations, potential cycling, and level of degradation. Therefore, various accelerated stress tests (ASTs) are carried out for a targeted degradation of different anode CLs based on Ir black or Ir oxide. It turns out that the OER mass activity method is robust, straightforward and an ideal method for e.g., in-house screening tasks. On the other hand, the VBA method is suitable for comparative analysis across laboratories by distinguishing between the three main overpotentials. The CT-VBA method, however, offers improved accuracy, as it accounts for mass transport overpotential at low current density, and is particularly suitable for determining apparent exchange current density values further used in modelling approaches. This benefit comes with a drawback, as commonly accepted reference Tafel slopes for respective catalyst type and PTL configurations would be required within the PEMWE community. This guidance therefore helps to choose the right method for determining OER metrics depending on the research question.

Performance and Durability of Heavy-Duty Fuel Cell Systems with an Advanced Ordered Intermetallic ORR Alloy Catalyst and Novel Support

Abstract Ordered PtCo intermetallic (OIM) catalyst (L10-PtCo/C) is a promising candidate as the oxygen reduction reaction (ORR) catalyst in hybrid fuel cell systems (FCS) for class-8 heavy duty (HD) trucks. Compared to a baseline annealed Pt on high surface area carbon (a-Pt/HSC) catalyst, its mass activity (MA) is 71% higher initially and 144% higher after 90,000 potential cycles in an accelerated stress test (AST). Analysis of the AST data indicates that the ORR kinetic constants do not change with aging and the degradation in the OIM catalyst activity is linearly proportional to the loss in the electrochemically active surface area (ECSA). Several operational strategies are investigated to mitigate catalyst degradation and achieve 25,000-h electrode lifetime and 2.5 kW/g Pt utilization on a HD truck duty cycle including load sharing with the hybrid battery, regulating the radiator fan power to maintain the coolant temperature close to 60oC, clipping the maximum cell voltage below 850 mV, limiting the ECSA loss to 55%, and oversizing the membrane active area by 20%. Drive cycle simulations indicate that the lifetime average voltage degradation rate is about 1.8 V/h and the integrated stack and FCS drive cycle efficiencies decrease by 3.5 to 3.9%.

Fine Engineering of d-Orbital Vacancies of ZnN4 via High-Shell Metal and Nonmetal Single-Atoms for Efficient and Poisoning-Resistant ORR.

Atomically dispersed metal-nitrogen-carbon (M-N-C) materials are active oxygen reduction reaction (ORR) catalysts. Among M-N-C catalysts, ZnN4 single-atom catalysts (SACs) due to a nearly full 3d10 electronic configuration insufficiently activate oxygen and display low ORR activity. To finely engineer d-orbital vacancies of ZnN4, we combine high-shell metal and nonmetal SAs as electronic regulators that are ZnN4Cl and carbon vacancy-hosted -Cl motifs, which show complementary electron-withdrawing capacities versus the ZnN4. Under that, the ZnN4 exhibits significantly enhanced ORR activity with a half-wave potential (E1/2) of 0.912 VRHE relative to the unmodified ZnN4 (E1/2 = 0.822 VRHE) and simultaneously robust durability (negligible activity loss after 10,000 potential cycles). Particularly, the engineered ZnN4 possesses high resistance to SCN- poisoning, which is rarely achieved among M-N-C SACs. Our works show that combining high-shell metal and nonmetal SAs can finely engineer d-orbital vacancies of metal centers to an optimal state, thereby intrinsically enhancing their catalytic performance.

Effect of N-Doped Carbon on the Morphology and Oxygen Reduction Reaction (ORR) Activity of a Xerogel-Derived Mn(II)O Electrocatalyst

This work synthesizes a xerogel from a sol–gel synthesis strategy and supports it on N-doped carbon support from spent coffee biomass (Mn(II)O/N-CC, hereafter MnO) as an efficient oxygen reduction reaction (ORR) catalyst in alkaline electrolytes. The effects of N-CC carbon content on MnO nanoparticle size, dispersion, distribution, morphology, and electrochemistry on ORR are discussed. The SEM and TEM measurements show that increasing the N-CC content during the MnO gelation reaction improved MnO dispersion and particle size during thermal treatment, increasing the ORR’s electrochemical active surface area. Several physiochemical and electrochemical characterizations show a clear relationship between N-CC catalysts and ORR activities. The best catalyst, MnO/N-CC-5, had an even distribution of 27 nm MnO nanoparticles on the N-CC support. The MnO/N-CC-5 catalyst had almost identical ORR kinetics and stability to those of the state-of-the-art Pt/C catalyst in 0.1 M KOH electrolytes, losing only 10 mV in half-wave potential after 5000 potential cycles and retaining 96% of current for over 10 h of continuous chronoamperometric stability. By measuring the electrochemical active surface areas of various catalysts by cyclic voltammetry at different scan rates and measuring the double layer capacitance (Cdl) and ECSA, MnO/N-CC-5 catalysts were shown to have enhanced ORR activity. The XPS analysis explains the ORR activity in terms of the Mn3+/Mn4+ ratio, and a mechanism was proposed. These findings suggest that the MnO/N-CC-5 catalyst could be a cathode catalyst in fuel cells, biofuel cells, metal–air batteries, and other energy conversion devices.

Effect of Chloride Ions on the Electrochemical Performance of Magnesium Metal‐Organic‐Frameworks‐Based Semi‐Solid Electrolytes

AbstractThe majority of research on magnesium (Mg) electrolytes has focused on enhancing reversible Mg deposition, often employing chloride‐containing electrolytes. However, there is a notable gap in the literature regarding the influence of chloride ions in semi‐solid Mg electrolytes. In this study, we systematically explore the impact of chloride ions on Mg deposition/dissolution on a copper (Cu) anode using a semi‐solid electrolyte composed of Mg‐based mixed metal‐organic frameworks, MgCl2 and Mg[TFSI]2. We separate the Mg deposition/dissolution process from changes in the anode's surface morphology In this respect, the morphological and compositional transformations in the electrolyte and electrode following galvanostatic cycling are meticulously investigated. Initial potential cycling reveals the feasibility of Mg deposition/dissolution on Cu electrodes, albeit with reduced reversibility in subsequent cycles. Extending the upper potential limit to 4.0 V vs. Mg/Mg2+ enhances Mg dissolution, attributed to chloride ions facilitating Cu surface dissolution. Our findings provide insights into optimizing semi‐solid electrolytes for advanced Magnesium battery technologies.

Carbon-anchoring synthesis of Pt1Ni1@Pt/C core-shell catalysts for stable oxygen reduction reaction

Proton-exchange-membrane fuel cells demand highly efficient catalysts for the oxygen reduction reaction, and core-shell structures are known for maximizing precious metal utilization. Here, we reported a controllable “carbon defect anchoring” strategy to prepare Pt1Ni1@Pt/C core-shell nanoparticles with an average size of ~2.6 nm on an in-situ transformed defective carbon support. The strong Pt–C interaction effectively inhibits nanoparticle migration or aggregation, even after undergoing stability tests over 70,000 potential cycles, resulting in only 1.6% degradation. The stable Pt1Ni1@Pt/C catalysts have high oxygen reduction reaction mass activity and specific activity that reach 1.424 ± 0.019 A/mgPt and 1.554 ± 0.027 mA/cmPt2 at 0.9 V, respectively, attributed to the optimal compressive strain. The experimental results are generally consistent with the theoretical predictions made by our comprehensive microkinetic model which incorporates essential kinetics and thermodynamics of oxygen reduction reaction. The consistent results obtained in our study provide compelling evidence for the high accuracy and reliability of our model. This work highlights the synergy between theory-guided catalyst design and appropriate synthetic methodologies to translate the theory into practice, offering valuable insights for future catalyst development.

Biomass derived Fe3C/Fe-Nx-C as cathode catalyst for oxygen reduction reaction in dual chamber microbial fuel cells

High cost and limited reserves of Pt based catalysts for oxygen reduction reaction (ORR) necessitates the development of cheap, earth abundant metal composed and sustainable catalysts for a variety of applications that include chemical fuel cells, zin-air batteries, and bioenergy devices such as microbial fuel cells (MFCs). In this work we developed a sustainable strategy for the synthesis of Fe based catalyst by using a solid-state synthesis method. Biomass derived from waste coffee is used as carbon source and a co-ordination complex formed from the EDTA: Fe along with melamine is used as N and Fe source. The pyrolysis of the resulting complex yields graphene like carbon sheets alongside atomically dispersed Fe atoms and clusters of Fe3C on the graphene like carbon sheets. The XRD and TEM measurements reveals atomically dispersed Fe atoms along with the clusters of Fe3C particles. The resulting Fe3C/Fe-Nx-C catalyst showed admirable ORR activity with a half-wave potential of 0.85 V vs RHE in 0.1 M HClO4 and 0.93 V vs RHE in 0.1 M KOH electrolytes with a nearly direct 4 electron transfer and excellent stability for about 10,000 potential cycles with just a loss of 50 mV of the half-wave potential. When used as cathode catalyst in dual chamber microbial fuel cells (DCMFs) with simulated organic matter as source of carbon, Fe3C/Fe-Nx-C catalyst delivered a volumetric power density of 95 mW m−3 and TOC analysis reveals the degradation of organic content of ⁓ 68 % over a period of 30 days continuous operation of DCMFs with atmospheric air as oxidant.

External ligand-free nickel-catalyzed synthesis of polypyrazines towards stable, high-capacity and low-potential sodium ion storage

Sodium ion batteries (SIBs) have been regarded as a promising alternative to lithium-ion battery owing to low cost and good sustainability, but its competitiveness in energy storage is still limited largely by the development of suitable electrode materials. Traditional inorganic anode materials for SIBs face the problems of sluggish electrochemical kinetics and large volume strain due to the insertion/extraction of large size Na+. By comparison, organic anodes have the advantages of abundance resources, renewability, and designability, but suffer from the lack of stable electrode materials with both high specific capacity and low redox potential. Here, a class of pyrazine rings-rich organic polymers (polypyrazines) were designed and synthesized through external ligand-free nickel-catalyzed carbon–carbon coupling reactions. Among them, poly(2,6-pyrazine) shows the lowest synthetic cost, the highest porosity and the best conductivity. Consequently, as the anode of SIBs, poly(2,6-pyrazine) delivers a low redox potential (about 1 V, vs Na+/Na), high-specific-capacity (617.2 mA h/g at 0.1 A/g), excellent rate-capability (300 mA h/g at 10 A/g) and long-term cycling stability (81 % after 1000 cycles at 1.0 A/g). The low preparation cost and outstanding electrochemical performance of poly(2,6-pyrazine) make it a promising anode candidate for further boosting the energy density of SIBs.

Perceptions of potential cycling infrastructure in a low-cycling context: Evidence from a medium-sized urban area

A key factor for the use of bicycles for transportation is the presence of safe and pleasant infrastructure. While research mostly focuses on large cities, cycling infrastructure and use are still incipient in many small and medium-sized cities. Because of their spatial context and very low and demographically uneven cycle use, it is key to understand how the potential of growing infrastructure is perceived among the general population, as well as how these perceptions differ based on personal characteristics. We focus on Camp de Tarragona (Catalonia, Spain), a polycentric urban area where bicycles are used for transportation for less than 1% of trips, and where local authorities have shown renewed interest in expanding and improving the current infrastructure to increase bicycle usage. We examine the perception of residents in the study area regarding various bicycle infrastructure scenarios through a visual preference analysis using photo evaluation. The representative survey was conducted with over 1,000 individuals in 2022, which demonstrates a widespread willingness to cycle as a means of transportation. However, this desire remains unmet due to inadequate infrastructure and an urban configuration that generally discourages cycling. The results show a need for recognizable, safe and segregated cycling infrastructure, though with differing perceptions between gender and age groups and between levels of urban density. The understanding of diverse sociodemographic nuances in the preferences of non-cyclists emerges as vital for promoting cycling as a feasible and socially inclusive transportation choice, highlighting the importance of tailored infrastructure to encourage cycling and enhance accessibility.

No Maunder Minimum phase in HD 4915

Context. The long-term solar magnetic activity and its cyclical behaviour, which is maintained by a dynamo mechanism, are both still challenging problems for astrophysics. In particular, an atypical event occurred between 1645 and 1715, when the solar activity was remarkably decreased and the number of sunspots was extremely reduced. However, the exact events that unfolded during the solar cycle remain unclear. The discovery of longer activity minima in cool stars may shed light on the nature of the complex mechanisms involved in the long-term behaviour of the solar-stellar dynamo. Aims. Our aim is to explore whether the G5V solar-like star HD 4915, which showed a striking chromospheric activity pattern in a previous study performed with HIRES data, might be considered a bona fide Maunder Minimum (MM) candidate. Methods. We analysed over 380 spectra acquired between 2003 and 2022 using the HARPS and HIRES spectrographs. We carried out a detailed search for activity signatures in HD 4915 by using the Mount Wilson and the Balmer Hα activity indexes. This task was performed by means of the generalised Lomb-Scargle periodogram. Results. The new HARPS data show that the chromospheric activity of HD 4915 is not decreasing. In fact, the increases in the activity after the broad minimum in three years reaches the level of activity before this phase, suggesting that it is not entering an MM phase. We also calculate a rotation period of 23.4 ± 0.2 d, which has not been reported before. Conclusions. HD 4915 shows a distinctive activity behaviour that was initially attributed to a possible and incipient MM phase. Additional HARPS data allowed us to discard an MM in the star. Our analysis shows that the complex activity pattern of HD 4915 might be ruled by a multiple activity cycle, in which a shorter cycle of 4.8 yr is modulated by a potential longer cycle. More activity surveys with extensive records and suitable cadence are crucial for an accurate identification of stars in magnetic grand minima.

Surface‐Engineered Pt‐Ni(111) Nanocatalysts for Boosting Their ORR Performance via Thermal Treatment

AbstractThe electrochemical oxygen reduction reaction (ORR) is critical for fuel cell application, and modifying surface structures of electrocatalysts has proven effective in improving their catalytic performances. In this study, we investigated surface‐engineered Pt−Ni nano‐octahedra subjected to annealing in various atmospheres. All octahedral nanocrystals retained their Pt−Ni {111} facets at an elevated temperature following the annealing treatments. Air annealing led to the formation of nickel‐rich shells on the Pt−Ni surface. In contrast, hydrogen (H₂) as a reducing gas facilitated the reduction of surface Ni species, incorporating them into the Pt−Ni bulk alloy, which resulted in superior mass activity and specific activity for ORR‐approximately 2.4 and 2.3 times as high as those from the unmodified counterpart, respectively. After 20,000 potential cycles, the H₂/Ar‐annealed Pt−Ni nano‐octahedra maintained a mass activity of 3.92 A/ , surpassing the initial mass activity of the unannealed counterparts (2.95 A/ ). These findings demonstrate a viable approach for tailoring catalyst surfaces to enhance performance in various energy storage and conversion applications.

Discovery and biological confirmation of a highly divergent Tacaribe virus in metatranscriptomic data from neotropical bats.

Clade B New World arenaviruses (NWA) include rodent-borne lethal hemorrhagic fever viruses, whereas Tacaribe virus (TCRV) stands out because of its detection in bats and its presumably low zoonotic potential. However, the bat association of TCRV was put into question by lethal experimental neotropical fruit bat infections and rare TCRV detection in bats. Scarce genomic data include near-identical viruses from Caribbean bats and ticks from the US sampled 50 years later. The prototype TCRV isolate used for experimental risk assessments has an extensive passage history in suckling mouse brains. Exploring the true genetic diversity, geographic distribution, and host range of bat-borne NWA is pivotal to assess their zoonotic potential and transmission cycles. We analyzed metatranscriptomic data for evidence of NWA identifying a highly divergent TCRV in bats and confirmed virus detection in original biological materials, supporting the association of TCRV with neotropical bats and warranting investigation of strain-associated TCRV pathogenicity.

High Oxygen Reduction Efficiency and Durability of Nano-Honeycomb Pt3(NiFeCo) Replenished by High-Entropy Metallic Glass Support.

Developing low-Pt oxygen reduction reaction (ORR) catalysts with high efficiency and robustness is critical for practical fuel cells. The most advanced ORR catalysts either feature high percentages of Pt (>70 at.%) or exhibit poor durability when reducing Pt loading. Herein, a multicomponent solid-solution Pt3(FeCoNi) honeycomb nano-framework supported by the specially designed high-entropy metallic glass (MG) is reported for efficient ORR. This hybrid catalyst with a low surface Pt loading of 5.79µgcm-2 displays exceptional mass and specific activities of 7.02Amgpt -1 and 8.15mAcmPt -2 at 0.9V, respectively, which are ≈15 and 22 times higher compared with commercial Pt/C. The analyses reveal the weakened chemisorption of oxygenated species, which is induced by the strong strain and ligand effects originating from the synergistic multicomponent alloying. This in turn enhances the intrinsic ORR activity. Moreover, benefiting from a unique replenishment behavior, the hybrid catalyst delivers ultra-high durability with negligible activity decay even after 50 000 potential cycles. This mechanism is achieved by sacrificing the interior MG supplementary support to dynamically compensate for the loss of catalytically active surface. The work provides an alternative way to design more efficient and durable low-Pt electrocatalysts for electrochemical devices.

Cobalt Nitride-Implanted PtCo Intermetallic Nanocatalysts for Ultrahigh Fuel Cell Cathode Performance.

Stable and active oxygen reduction electrocatalysts are essential for practical fuel cells. Herein, we report a novel class of highly ordered platinum-cobalt (Pt-Co) alloys embedded with cobalt nitride. The intermetallic core-shell catalyst demonstrates an initial mass activity of 0.88 A mgPt-1 at 0.9 V with 71% retention after 30,000 potential cycles of an aggressive square-wave accelerated durability test and loses only 9% of its electrochemical surface area, far exceeding the US Department of Energy 2025 targets, with unprecedented stability and only a minimal voltage loss under practical fuel cell operating conditions. We discover that regulating the atomic ordering in the core results in an optimal lattice configuration that accelerates the oxygen reduction kinetics. The presence of cobalt nitride decorated within PtCo superlattices guarantees a larger barrier to Co dissolution, leading to the excellent endurance of the electrocatalysts. This work brings up a transformative structural engineering strategy for rationally designing high-performing Pt-based catalysts with a unique atomic configuration for broad practical uses in energy conversion technology.

Prussian Blue-Derived Atomic Fe/Fe3C@N-Doped C Catalysts Supported by Carbon Cloth as Integrated Air Cathode for Flexible Zn-Air Batteries.

The development of an integrated air cathode with superior oxygen reduction reaction (ORR) performance is fundamental to flexible zinc-air batteries (ZABs) for wearable electronics. Herein, a self-assembled metal-organic framework (MOF)-derived strategy is proposed to prepare a atomic Fe/Fe3C@N-doped C catalysts supported by carbon cloth (CC) catalyst for use as an air cathode of flexible ZABs. The Prussian Blue precursor, which self-assembles on the surface of the carbon cloth due to electrostatic attraction, is critical in achieving the uniform dispersion of catalysts with high density loading on carbon cloth substrates. The hollow cubic structure, N-doped carbon layer coating, and the integrated electrode design can provide more accessible active sites and facilitate a rapid electron transfer and mass transport. Density functional theory (DFT) calculation reveals that the electronic interactions between the Fe-N4 and Fe3C dual active sites can optimize the adsorption-desorption behavior of oxygen intermediates formed during the ORR. Consequently, the Fe/Fe3C@N-doped C/CC exhibits an excellent half wave potential (E1/2 = 0.903V) and superior long-term cycling stability in alkaline environments. With excellent ORR performance, ZABs and flexible ZABs based on Fe/Fe3C@N-doped C/CC air cathode demonstrate excellent overall electrochemical performance in terms of open circuit voltage, maximum power density, flexibility, and cycling stability.

Sleep Disorders in Alzheimer’s Disease

Alzheimer’s disease is the leading cause of dementia worldwide. Patients typically exhibit cognitive impairment, memory loss, diminished social and occupational functioning, as well as language and motor disorders. Alzheimer’s disease is characterized by the abnormal accumulation of amyloid-β (Aβ) and phosphorylated tau in the brain. These pathological changes not only disrupt neuronal function and lead to cognitive deficits, but also interfere with sleep regulation, resulting in sleep disorders. Such disturbances can diminish nighttime sleep quality and contribute to daytime functional impairments, further exacerbating cognitive decline. Therefore, exploring the interplay between cognitive impairment, Alzheimer’s disease, and sleep disorders is crucial for enhancing the quality of life of Alzheimer’s patients. This review summarizes current literature on the interconnections among Alzheimer’s disease, cognitive impairment, and sleep disorders. Sleep disturbances are prevalent in Alzheimer’s patients and can also occur in those with amnestic mild cognitive impairment, which often precedes Alzheimer’s onset. Such sleep disorders may promote and accelerate the accumulation of amyloid-β and tau proteins [1-3]. Furthermore, Alzheimer’s patients may be more vulnerable to sleep disturbances, creating a potential vicious cycle. Further investigation into these relationships may provide valuable insights for the treatment or prevention of Alzheimer’s disease.