Glycosaminoglycans are structurally complex, linear polysaccharides. They show a hydrophilic effect and have the ability to bind water. In cosmetic preparations, they are obtained biotechnologically and appear in the form of hyaluronic acid, sodium hyaluronate and potassium hyaluronate. The aim of the study was to present the possibility of using glycosamidoglycans in cosmetology, trichology and aesthetic dermatology. These compounds are considered safe for topical application, they keep the skin in proper condition, support cell renewal, and increase the skin’s resistance to harmful external factors. They also bring satisfactory results in terms of application in trichology. A number of studies show that they stimulate hair growth, reduce excessive flaking of the scalp, seborrhea and support the treatment of androgenetic alopecia.