Postural Variables Research Articles

Early Supraspinal Influences on Human Embryonic Posture.

Knowledge of embryonic body posture as a reflection of neurodevelopment is limited. Here, we investigate embryonic body posture, preference, symmetry, and lateralization during periods of rest using virtual reality (VR) and four-dimensional (4D) ultrasound techniques to enhance our knowledge of neurodevelopment. It is hypothesized that lateralization and asymmetry in embryonic posture are absent. Embryos from low-risk pregnancies at 9 weeks gestational age (GA) were analyzed using a 30-min 4D ultrasound and VR techniques. In the middle of an embryonic resting period, the total body posture was determined by combining joint positions. Interindividual and intraindividual postures were analyzed over time to identify posture preferences, asymmetry, and lateralization. Sixteen embryos (N=210 middle frames out of 210 resting periods) displayed 27 different embryonic body postures. Interindividual and intraindividual variations in postures were seen. Asymmetry was noted in upper extremities, whereas lateralization of the head and spine was observed in nine embryos. Intraindividual and interindividual variation in embryonic posture at 9 weeks' GA is seen, suggesting the presence of supraspinal influences on body posture this early. Future interdisciplinary longitudinal studies on embryonic posture may provide further insights into embryonic central nervous system development, contributing to our understanding of embryonic health.

The association between aerobic capacity and spinal curvature and mobility in young soccer players

BackgroundThere is a lot of research in terms of injuries and performance in football and nowadays aerobic capacity, spinal posture and mobility have been taken into consideration separately in terms of performance. Considering from a biomechanical perspective, we thought spinal curvature and mobility may affect aerobic performance and investigated the relationship between them. Research questionDo young soccer players' segmental spinal curvature and mobility affect their aerobic capacity and maximal exercise performance? MethodsThirty-four young league players (mean age 16.56 ±1.11 years) were evaluated pre-season. Spinal assessments in the sagittal plane with a non-invasive, computer-assisted electromechanical device and aerobic capacity assessment with a cardiopulmonary exercise-testing device were applied. The relationship between spinal postural variables with aerobic capacity was done by Pearson correlation analysis, and simple linear regression analysis was used to estimate the effect of spinal curvature and mobility on aerobic performance. ResultsVarious parameters of aerobic performance were related to spinal curvature and mobility. Maximal oxygen uptake (VO2max) and maximal heart rate (HRmax) were negatively correlated with thoracic angle (r=-0.343, p=0.047 and r=-0.344, p=0.046; respectively). Thoracic angle was also associated with tidal volume (VT) and VO2/HR (r=-0.347, p=0.044 and r=-0.348, p=0.044; respectively). Higher thoracic mobility caused to reach the anaerobic threshold (VAT) earlier (r=-0.368, p=0.032), at a lower speed (r=-0.367, p=0.033). In other segments, lumbar mobility was negatively correlated with VT at VAT (r=-0.346; p=0.045), while spinal inclination with HR at VAT (r=-0.387, p=0.024). SignificanceAlthough it is within physiological ranges, increased spinal curvature and mobility are associated with a decrease in aerobic capacity in young soccer players. Spinal curvature and mobility especially in the thoracic region may affect the aerobic performance of a soccer player. The trainers should consider spinal alignment for not only the technical and tactical but also the general performance of the soccer player.

Predictive Value of the Postural Difference in Antero-Posterior Diameter of Renal Pelvis on Ultrasonography of Unilateral Ureteropelvic Junction Obstruction in Determining the Need For Surgery.

Ureteropelvic junction obstruction (UPJO) is the most common cause of antenatal hydronephrosis. Although majority of them improve with time, none of the existing diagnostic modalities can accurately predict which hydronephrotic kidney is at the risk of progressive renal damage and will benefit from early surgery. Postural variations in the anteroposterior pelvic diameter (APPD) of the hydronephrotic kidney in children during follow-up postnatal ultrasonography (USG) reflect the intrapelvic tension, which might help in predicting the need of surgery amongst these patients. We designed this prospective observational study in all unilateral UPJO patients on postural variation in the APPD of renal pelvis on ultrasonography. The mean age of all patients were 2.15 years (0-5 years) and managed at our institute at All India Institute of Medical Sciences, Bhubaneswar. The study duration was from July 2019 to May 2021. The management of these patients was done as per the standard institutional protocol and there was no deviation due to inclusion in this study. We documented the variations in postural APPD both amongst the conservatively managed group and the surgically managed group of patients. Linear correlation between two continuous variables was explored using Pearson's correlation (if the data were normally distributed) and Spearman's correlation (for non-normally distributed data). We found a higher prone APPD than supine APPD in all these patients indicating the obstruction at ureteropelvic junction. However, in the surgical group, there was less variation in the postural APPD compared to the conservative group, and when there was no variation in the postural APPD, the need of surgery was 100%. The limitation of our study was the small sample size (n = 36). A study involving a larger population or involving multiple institutions may further add significance to our findings. We found less postural variation in APPD on USG to be more likely associated with severe UPJO requiring early surgery. This may indicate a non-compliant renal pelvis. However, it was statistically not significant.

Impact of manual therapy on body posture-3-D analysis with rasterstereography – pilotstudy

IntroductionThe relationship between posture and temporomandibular disease (TMD) is unclear. The aim of our study was to determine the influence of manual therapy (MT) on posture in TMD patients compared with healthy subjects.Material/methodAfter consideration of inclusion and exclusion criteria, 30 subjects were included. These were divided into two groups: group A comprised 15 healthy subjects and group B 15 patients with present proven TMD disease. Rasterstereographic images were taken at different times. Group A subjects were scanned twice within half a year and group B before initiation as well as after the first MT and after completion of the prescribed MT. The different posture variables were calculated using DIERS Formetric software.ResultsTo illustrate the differences between the two groups, 10 different postural variables were examined. Significant differences between the two groups were observed in pelvic tilt, surface rotation, and kyphotic apex. Pelvic tilt: mean = 7.581, p-value = 0.029; surface rotation: mean = 3.098, p = 0.049; and mean kyphotic apex = 11.538 and 11.946, respectively, with p-values of 0.037 and 0.029, respectively.ConclusionMT leads to a change in posture in TMD patients. This could influence the course of TMD treatment.

Biomechanical analysis of the snatch technique for elite and varsity weightlifters

Understanding the importance of movement asymmetries and variations in technique proficiency across different level of weightlifters is crucial. The purpose of this study was to examine differences in joint kinematics, muscle activation, and barbell parameters between elite and varsity weightlifters during the snatch utilizing integrated 3D motion capture and EMG systems. In addition, it analyzes symmetries in joint kinematics and muscle activation in both groups. Ten female participants, comprising 5 elite and 5 varsity weightlifters, along with thirteen male participants, consisting of 6 elite and 7 varsity weightlifters during snatch were measured. Several asymmetries in posture and muscle activation were identified in both elite and varsity weightlifters. In addition, elite weightlifters exhibited significantly more flexed knees than varsity counterparts (p < 0.05) at the conclusion of the second pull and at the highest position of the barbell. Furthermore, significantly lower activity in gluteus maximus was detected in elite weightlifter at the highest point of the barbell than in the varsity groups (p < 0.05). Moreover, elite males achieved a lower maximum height for the barbell compared to varsity males (p = 0.006). Furthermore, elite females demonstrated less horizontal displacement (D2x) (p = 0.005) than varsity counterparts. Varsity women presented significantly lower horizontal velocity (p = 0.003) at the conclusion of the second pull than varsity counterparts. Despite several asymmetries detected, those may not be critical factors in achieving a successful snatch lift, given that all weightlifters successfully completed the lift. However, variations in posture and muscle activation may still be associated with improvements in technique proficiency across different levels of weightlifters.

Cerebellar Haemorrhage After Corrective Surgery for Scoliosis in a Girl with Arrested Hydrocephalus.

A 14-year-old girl with congenital hydrocephalus and early-onset scoliosis presented with sudden onset of severe headache on the fourth postoperative day of scoliosis correction (definitive fusion). On evaluation, she was found to have cerebellar haemorrhage on computed tomography scan with the findings of obstructive hydrocephalus. Posterior fossa bleed with hydrocephalus contributing to raised ICP was suspected initially. Headache persisted despite treating the patient with analgesics and antioedema measures. There was no history of postural variation of headache. As the drain output was not coming down, even by the sixth postoperative day, low cerebrospinal fluid pressure headache was considered and the drain was removed, which resulted in marked improvement of headache. Subsequent wound exploration revealed grade III dural tear at D10 level, which was repaired and the headache subsided completely. The linear pattern of haemorrhage in the cerebellum is classical of remote cerebellar haemorrhage, which is seen rarely following spinal surgeries with associated dural tear.

Reconfigurable Robotic Exercising Companion

Regular exercise plays a crucial role in promoting overall well-being in today’s lifestyle. However, individuals often find it challenging to properly execute exercises, including maintaining correct postures and appropriate movement speeds. Robotic companions have emerged as potential solutions to assist and motivate users during exercise sessions. This research paper proposes a novel robot companion designed for exercise scenarios using a reconfigurable robot. In contrast to existing non-reconfigurable robotic companions, the use of a reconfigurable robot provides added flexibility in generating emotions. The system incorporates a module that utilizes fuzzy logic to evaluate the correctness of exercise performance based on posture variations and movement speeds. The robot generates emotions and provides feedback to users based on the exercise correctness score. The robot expresses emotions through reconfigurations, motion patterns, and variations in robot speed. This emotion-based feedback could be helpful for creating engaging and interactive exercise experiences. Apart from emotion generation, the robot utilizes vocal cues as feedback. Experimental results validate the effectiveness of the proposed system in evaluating exercise correctness and demonstrating meaningful emotion transitions. The findings of this work contribute to the development of innovative robotic companions for improving exercise adherence and overall well-being.

An accessible and intuitive approach to 3D data modeling for morphometric surface evaluation in pig farming

The recording of pig surfaces allows for the estimation of growth-related body size dimensions from which the animals’ condition can be inferred. Furthermore, for purposes such as animal breeding, it is of particular interest to describe the shape variations within the population. Therefore, we built a Statistical Shape Model (SSM) that enables a quantitative and visual exploration of variation in size, form and posture in an intuitive way.We included 4315 images from 582animals with a body weight ranging from 50 to 140 kg. After data processing, i.e. the removal of data points corresponding to the head and tail, the 3D point clouds were reduced to an equal number of reference points. These reference points were arranged so that the pig surface could be reconstructed via Bézier surface patches. Then, Procrustes Analysis was performed to align the reference points from all shapes. A mean shape and its main modes of variation were derived, some of which were used to correct the posture of the animals.A linear regression for weight prediction resulted in a mean absolute error of 5.06 kg before and 2.84 kg after data processing. The median error of surface reconstruction was 2.5 mm taking eight surface patches with 45 reference points and 1.3 mm taking 32 surface patches with 153 reference points into account. The first six modes of variation from the SSM indicated differences in size and posture. Interestingly, regions prone to noise were also revealed.In conclusion, we present a novel approach that can be used to receive a compact number of corresponding data points, providing data that is easier and more efficient to handle while exposing shape-specific attributes. Our approach is helpful to visualize and compare shapes, including the collection of body size measurements as well as unsupervised and supervised clustering for more objective data-driven decision-making.

Individualized dose calculation for internal exposure on radionuclide intake: GPU acceleration approach

Objective. The rapid and accurate assessment of internal exposure dose is a crucial safeguard for personnel health and safety. This study aims to investigate a precise and efficient GPU Monte Carlo simulation approach for internal exposure dose calculation. It directly calculates doses from common radioactive nuclides intake, like 60Co for occupational exposure, allowing personalized assessments. Approach. This study developed a GPU-accelerated Monte Carlo program for internal exposure on radionuclide intake, successfully realizing photoelectronic coupled transport, nuclide simulation, and optimized acceleration. The generation of internal irradiation sources and sampling methods were achieved, along with the establishment of a personalized phantom construction process. Three irradiation scenarios were simulated to assess computational accuracy and efficiency, and to investigate the influence of posture variations on internal dose estimations. Main results. Using the International Commission on Radiological Protection (ICRP) voxel-type phantom, the internal dose of radionuclides in individual organs was calculated, exhibiting relative deviation of less than 3% in comparison to organ dose results interpolated by Specific Absorbed Fractions in ICRP Publication 133. Employing the Chinese reference phantom for calculating internal irradiation dose from the intake of various radionuclides, the use of GPU Monte Carlo program significantly shortened the simulation time compared to using CPU programs, by a factor of 150–500. Internal dose estimation utilizing a seated Chinese phantom revealed up to a 75% maximum difference in organ dose compared to the same phantom in a standing posture. Significance. This study presents a rapid GPU-based simulation method for internal irradiation doses, capable of directly simulating dose outcomes from nuclide intake and accommodating individualized phantoms for more realistic and expeditious calculations tailored to specific internal irradiation scenarios. It provides an effective and feasible tool for precisely calculating internal irradiation doses in real-world scenarios.

The Motor Optimality Score-Revised Improves Early Detection of Unilateral Cerebral Palsy in Infants with Perinatal Cerebral Stroke.

Neonatal cerebral stroke includes a range of focal and multifocal ischemic and hemorrhagic brain lesions, occurring in about one of 3000 live births. More than 50% of children with neonatal stroke develop adverse outcomes, mainly unilateral cerebral palsy. Asymmetries in segmental movements at three months have been proven to be an early sign of CP in infants with unilateral brain damage. Recognition of additional early signs could enhance prognostic assessment and enable an early and targeted intervention. The aim of the study was to assess early signs of CP in infants with arterial cerebral stroke through the General Movements Assessment and the Motor Optimality Score-Revised (MOS-R). Twenty-four infants born at term (12 females and 12 males) diagnosed with ACS, and 24 healthy infants (16 females and 8 males) were assessed. The GMs (fidgety movements) and MOS-R were assessed from videos recorded at 11-14 weeks of post-term age. Cognitive and motor outcomes were assessed at 24 months using the Griffiths III developmental quotient and Amiel-Tison neurological examination. The gross motor function classification system expanded and revised (GMFCS-E&R) was adopted to categorize CP. Among infants with ACS, 21 (87.5%) developed unilateral CP. Most of them showed non-disabling CP (14 had GMFCS-E&R grade 1 [66.6%], 6 grade 2 [28.6%], and 1 grade 5 [4.8%]). Fidgety movements (FMs) were absent in 17 (70.8%), sporadic in 4 (16.7%) infants, and normal in 3 (12.5%). Segmental movement asymmetry was found in 22/24 (91.7%). According to the MOS-R, motor items (kicking, mouth movements), postural patterns (midline centered head, finger posture variability), and movement character (monotonous and stiff) were statistically different among infants with ACS and healthy infants. The MOS-R median global score was lower in the group with ACS compared to the control group (6 vs 26; p < 0.01). FMs, segmental movement asymmetry, and MOS-R global score were significantly correlated with abnormal outcome. MOS-R global scores less than or equal to 13 had 100% specificity and sensitivity in predicting GMFCS-E&R grade ≥ 2 CP in infants with ACS. The rate of CP was high among infants with ACS, but in most cases it showed low GMFCS-E&R grades. The study highlighted a significant correlation between MOS-R, together with absent FMs and unilateral CP in infants with ACS. Moreover, the MOS-R showed high sensitivity and specificity in the prediction of CP. Combined assessment of FMs and MOS-R could help to better identify infants at high risk of developing UCP in a population of infants with ACS. Early identification of precocious signs of unilateral CP is fundamental to providing an early individualized intervention.

A Novel Unsupervised Machine Learning Approach to Assess Postural Dynamics in Euthymic Bipolar Disorder.

Bipolar disorder (BD) is a mood disorder with different phases alternating between euthymia, manic or hypomanic episodes, and depressive episodes. While motor abnormalities are commonly seen during depressive or manic episodes, not much attention has been paid to postural abnormalities during periods of euthymia and their association with illness burden. We collected 24-hour posture data in 32 euthymic participants diagnosed with BD using a shirt-based wearable. We extracted a set of nine time-domain features, and performed unsupervised participant clustering. We investigated the association between posture variables and 12 clinical characteristics of illness burden. Based on their postural dynamics during the daytime, evening, or nighttime, participants clustered in three clusters. Higher illness burden was associated with lower postural variability, in particular during daytime. Participants who exhibited a mostly upright sitting/standing posture during the night with frequent nighttime postural transitions had the highest number of lifetime depressive episodes. Euthymic participants with BD exhibit postural abnormalities that are associated with illness burden, especially with the number of depressive episodes. Our results contribute to understanding the role of illness burden on posture changes and sleep consolidation in periods of euthymia.

Analysis of the dynamic performance of pantograph-catenary system with posture of pan-head

Abstract This article focuses on the changes in the contact pressure between the pantograph and the catenary caused by variations in the pan-head posture. Starting from the kinematics and dynamics of the pantograph and based on the theories of multibody dynamics and finite element analysis, the pantograph head model is validated, and a pantograph rigid-flexible coupling model considering the flexibility of the pantograph head is established. A coupling model between the pantograph model and the rigid contact catenary is established to extract the pantograph posture and dynamic performance data during operation. By finely considering and modeling the structural characteristic parameters of the pantograph, the influence of different pantograph head characteristic parameters on the dynamic performance of the catenary system is studied. This provides a research basis for understanding the degree of influence of different characteristic parameters on the catenary dynamics.

Influence of initial belt torso contact on the kinematics and kinetics of booster-seated ATDs in frontal-oblique impacts

Objective Varying initial belt torso contact (i.e., belt gap) on belt-positioning boosters may have implications for potential shoulder belt slip-off in low-speed evasive vehicle maneuvers and differences in dynamic outcomes in frontal sled tests. This study evaluated the influence of initial booster belt gap and belt fit conditions on the kinematic and kinetic outcomes during frontal oblique impacts. Methods Frontal oblique (+15° from frontal) sled tests (n = 18; 23.6 ± 0.1 g at 12.4 ± 0.1 ms) were conducted using the Q-Series 6-year-old (Q6) and 10-year-old (Q10) and the Large Omni Directional Child (LODC) anthropomorphic test devices (ATDs). Various initial belt fit and belt gap conditions were investigated by evaluating each ATD on 2 high-back (HB), 3 low-back (LB), and 1 low-profile (Low) booster. Initial belt fit and belt gap were quantified, and boosters were categorized as “smaller gap” or “larger gap” for comparison. Results Larger-gap boosters produced greater peak lumbar FY and MZ (HB: −23.2 ± 8.8 Nm, LB: −23.6 ± 9.7 Nm) compared to smaller-gap boosters (HB: −12.6 ± 4.4 Nm, LB/Low: −12.4 ± 7.2 Nm) for the LODC and Q10. Peak axial torso rotations were also observed for larger-gap LB (38.6°) compared to smaller-gap LB boosters (23.8°), and the LODC experienced greater peak thoracic rotations on larger-gap boosters compared to smaller-gap boosters. These results suggest that ATDs on larger-gap boosters experienced greater torso rotation and lumbar MZ due to lack of initial contact between the shoulder belt and inferior torso. No ATDs experienced complete shoulder belt slip-off; however, larger-gap boosters displayed more visual evidence of outboard shoulder belt positioning at the time of peak forward head excursion. Conclusion This study provides a novel investigation on the role of initial belt fit and belt gap metrics on the dynamic response of booster-seated ATDs in frontal oblique impacts. Larger-gap boosters allowed the torso to undergo greater axial rotation before restraint was provided by the shoulder belt to the lower torso. Increased shoulder rotations may indicate greater propensity for shoulder belt slip-off in more severe crashes, in oblique maneuvers, or with variations in initial occupant posture. These results suggest the importance of continued evaluation of the implications of initial belt gap provided by boosters and the importance of evaluating lumbar FY and MZ and useful metrics for discrimination of differences in ATD response across booster designs.

Human height estimation using AI-assisted computer vision for intelligent video surveillance system

In urban areas, technological advancements have led to an increased focus on height as a critical human characteristic for surveillance purposes. Face recognition often encounters challenges due to occlusion and masks, necessitating the use of height, build, and torso. Accurately estimating human height in surveillance scenarios is complex due to camera calibration, posture variations, and movement patterns. This research introduces a novel human height estimation method for surveillance systems, along with a dedicated dataset. The process begins with camera calibration to rectify lens distortions. A deep learning-based YOLOv7-Occlusion Aware (YOLOv7-OA) target detection technique is employed to precisely locate individuals within the frame. The study assesses the impact of camera height and deflection angle on height estimation across different areas of the field of vision (FOV). The proposed method yields a mean absolute error of 0.02 cm to 0.8 cm across various FOV zones, surpassing the previous 1.39 cm benchmark findings.

Grasp Posture Variability Leads to Greater Ipsilateral Sensorimotor Beta Activation During Simulated Prosthesis Use

Motor behaviour using upper-extremity prostheses of different levels is greatly variable, leading to challenges interpreting ideal rehabilitation strategies. Elucidating the underlying neural control mechanisms driving variability benefits our understanding of adaptation after limb loss. In this follow-up study, non-amputated participants completed simple and complex reach-to-grasp motor tasks using a body-powered transradial or partial-hand prosthesis simulator. We hypothesised that under complex task constraints, individuals employing variable grasp postures will show greater sensorimotor beta activation compared to individuals relying on uniform grasping, and activation will occur later in variable compared to uniform graspers. In the simple task, partial-hand variable and transradial users showed increased neural activation from the early to late phase of the reach, predominantly in the hemisphere ipsilateral to device use. In the complex task, only partial-hand variable graspers showed a significant increase in neural activation of the sensorimotor cortex from the early to the late phase of the reach. These results suggest that grasp variability may be a crucial component in the mechanism of neural adaptation to prosthesis use, and may be mediated by device level and task complexity, with implications for rehabilitation after amputation.

Analysis of the Motion Postures in Equestrian Sports Based on Multi-Sensor Data Fusion

Horse riding, in its essence, is both an art and a captivating sport. In these events, riders showcase their refined skills and deep bond with their horses, most notably through changes in physical positioning. This research aims to accurately capture and analyze the spatial postures of riders in equestrian sports, exploring the dynamic differences between professional and amateur riders. To achieve this, we employed a multi-sensor data fusion approach based on human kinetics theories, enhanced by an extended Kalman filter. This method, combined with an optical tracking system, enabled us to intricately compare and analyze the 3D postures of riders during walking and trotting phases. Our research captured these nuanced postural shifts using an inertial sensor network, yielding nine-axis motion data of riders during their performance. The accuracy of our fusion technique was validated using the optical tracking system. By analyzing the motion data, we discerned posture variations among the riders of differing expertise levels, even when executing the same riding technique. The insights from this research offer a quantifiable metric for refining equestrian training and contribute to understanding the complex dynamics of rider–horse interaction.

The Vestibulospinal Nucleus Is a Locus of Balance Development.

Mature vertebrates maintain posture using vestibulospinal neurons that transform sensed instability into reflexive commands to spinal motor circuits. Postural stability improves across development. However, due to the complexity of terrestrial locomotion, vestibulospinal contributions to postural refinement in early life remain unexplored. Here we leveraged the relative simplicity of underwater locomotion to quantify the postural consequences of losing vestibulospinal neurons during development in larval zebrafish of undifferentiated sex. By comparing posture at two timepoints, we discovered that later lesions of vestibulospinal neurons led to greater instability. Analysis of thousands of individual swim bouts revealed that lesions disrupted movement timing and corrective reflexes without impacting swim kinematics, and that this effect was particularly strong in older larvae. Using a generative model of swimming, we showed how these disruptions could account for the increased postural variability at both timepoints. Finally, late lesions disrupted the fin/trunk coordination observed in older larvae, linking vestibulospinal neurons to postural control schemes used to navigate in depth. Since later lesions were considerably more disruptive to postural stability, we conclude that vestibulospinal contributions to balance increase as larvae mature. Vestibulospinal neurons are highly conserved across vertebrates; we therefore propose that they are a substrate for developmental improvements to postural control.

Episodic Hyponatremia in Acute Intermittent Porphyria: A Case Report

Background: Acute intermittent porphyria (AIP) is an uncommon, ubiquitously distributed autosomal dominant disorder with low penetrance characterized by decreased enzyme activity of hydroxymethylbilane synthase (HMBS) an enzyme of heme synthesis pathway. It is often an elusive diagnosis due to rarity and non-specific signs and symptoms. Case report: A 28 years old female from Nawalparasi (district in central Nepal) presented with history of recurrent episodes of abdominal pain and vomiting. Her current episode began two weeks before presentation to our center. Abdominal pain was diffuse, colicky in nature without exacerbating or relieving factor. There was no postural or diurnal variation. On examination, there was no tenderness and abdominal examination findings were unremarkable. Her biochemical investigations were unremarkable except for severe hyponatremia (S. Na of 100mmol/L) which was SIADH/SIADH like presentation (Table 1 and Table 2). Severe episodic hyponatremia, port-wine color of urine, gastrointestinal symptoms and previous hospital stay two years back with similar episode of hyponatremia and abdominal pain were valuable clues for suspicion of acute porphyria. On further evaluation, patient was found to have presence of porphyrogenic precursors in urine and diagnosis of acute intermittent porphyria was confirmed. After diagnosis, she was managed conservatively with carbohydrate loading with intravenous dextrose, opioids and pregabalin as analgesics. Her symptoms gradually improved, hyponatremia subsided and was discharged in normal condition. Conclusion: Acute intermittent porphyria has signs and symptoms common to several clinical, neurological, psychiatric and gastroenterological pathologies, which complicate diagnosis. In young patients with hyponatremia (with SIADH –like picture), AIP should be considered in differential diagnosis.

Quantifying rider posture variability in powered two- and three-wheelers for safety assessment

Objective Injury outcomes for powered two- and three-wheeler (PTW) riders are influenced by the rider posture. To enable analysis of PTW rider accidents and development of protection systems, detailed whole-body posture data is needed. Therefore, the aim of this study is to fill this gap by providing collections of average male whole-body postures, including subpopulation variability, for different PTW types. This will enable future studies to explore the influence of PTW rider posture variation and to support safety system development. Methods 3D photometric measurements of 51 anatomical landmarks were recorded on 20 (50th percentile male) volunteers in their preferred riding postures across three PTW types (naked, scooter, and touring). Following an outlier removal process, a principal component analysis (PCA) was performed to calculate average postures and principal components (PCs), to describe the observed posture variation, for each PTW. The visualization of the PCs was facilitated through kinematic linkage representations, connecting anatomical landmarks and estimated joint centers to form segments and characteristic joint angles. Results The first seven PCs explained 80% of the variance in posture for each of the three PTWs. Across PTWs, these PCs frequently described combinations of postural features including variation in fore-aft seat positions, pelvic tilt, spinal curvature, head position, and extremity flexion-extension. Analysis revealed distinct differences in average postures across the three PTWs, on average, 10 ± 9° for the characteristic joint angles within a min-to-max range between the three PTWs. However, for all three PTWs, the variability between volunteers in characteristic joint angles on the same PTW were on average more than twice as large within a ± 2 SD range (26 ± 11°). Conclusions The results suggest that PTW rider posture variation must be addressed by involving simultaneous adjustments of multiple body parts, as described by each of the first seven PCs, as a direct consequence of the human body interconnectedness. Furthermore, the study’s findings challenge conventional assumptions that the relative distance between PTWs’ handlebar, seat, and foot support predominantly influences rider postures. Instead, the research demonstrates that individual variability has a substantial influence on rider posture and should be considered in PTW safety development.

A pose estimation for motion tracking of infants cerebral palsy

AbstractThe General Movements Analysis (GMA) has demonstrated noteworthy promise in the early detection of infantile Cerebral Palsy (CP). However, it is subjective and requires highly trained clinicians, making it costly and time-consuming. Automation of GMA could potentially enhance accessibility and further our comprehension of infants’ full-body movements. This paper investigates the feasibility of using 2D and 3D pose estimation strategies to observe and scrutinize the infant’s comprehensive body movement attributes to improve our perspective to consider joint movement and positions over time as an alternative to GMA for early CP prediction. The study includes comprehensive movement analysis from video recordings for accurate and efficient analysis of infant movement by computing various metrics such as angle orientations at different predicted joint locations, postural information, postural variability, movement velocity, movement variability, and left–right movement coordination. Along with antigravity movements are assessed and tracked as indicators of CP. We employed a variety Machine Learning (ML) algorithms for CP classification based on a series of robust features that have been developed to enhance the interpretability of the model. The proposed approach is assessed through experimentation using the MINI-RGBD and RVI-38 datasets with a classification accuracy of 92% and 97.37% respectively. These results substantiate the efficacy of employing pose estimation techniques for the precocious prediction of infantile CP, highlighting the importance of monitoring changes in joint angles over time for accurate diagnosis and treatment planning.