Post-test Research Articles

The Integration of Educational Technology in Teaching Filipino in Taganito National High School, Claver, Surigao Del Norte, Division of Surigao Del Norte: A Program

The study determined the effectiveness of integrating educational technology in teaching the Filipino Subject for Grade 9 students in Taganito National High School. The study employed a quasi-experimental research design utilizing two homogenized group comprising 30 students per group. Data gathered were analyzed using the mean and standard deviation, T-test for dependent samples, and analysis of co-variance (ANCOVA). Results revealed that the average post test scores of Grade 9 students in Filipino subject is mostly Very High both in the Control (M=9.12; SD=.38) and in the Experimental (M=9.41; SD=.31). Learning performance of Grade 9 students in the Experimental Group is significantly higher (p=.002) compared to that of the Control Group. Therefore, the use of educational technology in teaching the Filipino subject is highly effective. Students’ learning achievement in Filipino subject is significantly enhanced with the effective use of educational technology in instruction. Thus, it is recommended that the Grade 9 teachers handling the Filipino subjects are enjoined to effectively use educational technology in teaching the subject. Moreover, the learning modules used in this study may be adopted by other Filipino teachers as teaching interventions in teaching the Grade 9 students.

PATIENT WITH CHRONIC CORONARY SYNDROME: USE OF MULTIMODAL IMAGING FOR CORRECT DIAGNOSIS AND TREATMENT

Abstract In the context of CCS, CCTA allows us to discriminate with almost certainty between patients with the absence of disease. In case of a positive test, the characteristics of the plaque allow to stratified risk of developing future events. In doubtful cases it is necessary to resort to a multimodal imaging strategy for the correct diagnosis. We present the case of a 63-year-old hypertensive and dyslipidemic man who started presenting two months ago episodes of asthenia associated with tachycardia and jugular constriction after taking the usual CCB therapy. With a pre-test probability of 26%, a CCTA scan was requested which highlighted a non-calcific fibrous plaque (Image 1) at the level of the middle circumflex inducing a moderate stenosis (Cad-Rads 3). The patient underwent coronary angiography which confirmed this lesion and also highlighted a similar one downstream of the first. (Image 2) The OCT evaluation showed: 7 mm eccentric fibrous proximal plaque with evidence of multiple intimal layers (Healed plaque) in its distal third and with evidence of a medial-intimal flap involving three quadrants in the proximal two thirds (270°), with current intact endothelium and presence of neo-angiogenesis; MLA 2.33 mm² and AS 70%. Picture compatible with healed spontaneous dissection of the vessel. (Image 3) The subsequent 12 mm concentric plaque (360° involvement of the vessel) had a predominantly lipid component with macrophages and fibrous cap of 60 µm, MLA of 2.3mm² and AS 72%. Panel compatible with high risk plaque. (Image 4) It was decided to implant a 3.5x26mm drug-eluting stent through OCT-guided PCI with final MSA of 7.62 mm², stent expansion of 81%, absence of dissections at the edges and residual distal edge plaque with MLA of 7.6 mm². (Image 5). Conclusions Healed plaques are more frequent in patients with CCS and represent a plaque complicated by medial-intimal ulceration subsequently healed by neo-endothelialization. On CCTA they appear as non-calcific fibrous plaques with an intermediate density expressed in Hounsfield Units but the definitive diagnosis can only be obtained using an Intravascular Imaging method (OCT in the case presented). The patient appears asymptomatic after resuming his usual antihypertensive therapy at 30-day FU.

Correction to: The effect of local neighbourhood park redevelopments on park visitations and user physical activity levels: a pre–post test evaluation

Correction to: The effect of local neighbourhood park redevelopments on park visitations and user physical activity levels: a pre–post test evaluation

Analyzing the dynamics of monetary policy and economic growth in Ethiopia: an autoregressive distributed lag (ARDL) approach

Numerous studies conducted by various scholars have aimed to ascertain the impact of monetary policy on economic growth. However, these empirical investigations have not reached a unanimous consensus. Therefore, this study analyzes the effect of monetary policy. To address this objective, this study employed ARDL and error correction model (ECM) based on annual data from 1993 to 2022. Granger causality test was also employed to check the direction of causal effects of one variable on the other variable. All required pre and post estimation tests were performed and verified that the model was statistically viable. The study revealed that, in the short run, deposit interest rate, reserve required amount, and open market operation have positive and statistically significant effects on real GDP growth of Ethiopia; however, money supply has negative and statistically significant effects on real GDP growth of Ethiopia. In the long run, money supply has positive and statistically significant effects on real GDP growth of Ethiopia; however, deposit interest rate and reserve required have negative and statistically significant effects on real GDP growth of Ethiopia. To sum up, in the short run, contractionary monetary policy was promising, and in the long run, expansionary monetary policy was favorable for economic growth. The Granger causality test result shows that there is bidirectional causality between monetary policy and economic growth; except there was a unidirectional relationship between deposit interest rate and economic growth. Ultimately, this research suggests the following policy recommendation: for short-term economic enhancement, it is advisable for the government to opt for a contractionary monetary policy rather than an expansionary one. On the other hand, for long-term economic improvement, an expansionary monetary policy is more favorable than a contractionary one.

Diagnostic Identification of Acute Brain Dysfunction in Pediatric Sepsis and Septic Shock in the Electronic Health Record: A Comparison of Four Definitions in a Reference Dataset.

Acute brain dysfunction (ABD) in pediatric sepsis has a prevalence of 20%, but can be difficult to identify. Our previously validated ABD computational phenotype (CPABD) used variables obtained from the electronic health record indicative of clinician concern for acute neurologic or behavioral change. We tested whether the CPABD has better diagnostic performance to identify confirmed ABD than other definitions using the Glasgow Coma Scale or delirium scores. Diagnostic testing in a curated cohort of pediatric sepsis/septic shock patients. Quaternary freestanding children's hospital. The test dataset comprised 527 children with sepsis/septic shock managed between 2011 and 2021 with a prevalence (pretest probability) of confirmed ABD of 30% (159/527). CPABD was based on use of neuroimaging, electroencephalogram, and/or administration of new antipsychotic medication. We compared the performance of the CPABD with three GCS/delirium-based definitions of ABD-Proulx et al, International Pediatric Sepsis Consensus Conference, and Pediatric Organ Dysfunction Information Update Mandate. The posttest probability of identifying ABD was highest in CPABD (0.84) compared with other definitions. CPABD also had the highest sensitivity (83%; 95% CI, 76-89%) and specificity (93%; 95% CI, 90-96%). The false discovery rate was lowest in CPABD (1-in-6) as was the false omission rate (1-in-14). Finally, the prevalence threshold for the definitions varied, with the CPABD being the definition closest to 20%. In our curated dataset of pediatric sepsis/septic shock, CPABD had favorable characteristics to identify confirmed ABD compared with GCS/delirium-based definitions. The CPABD can be used to further study the impact of ABD in studies using large electronic health datasets.

Digitalization and Branding of Agung Manunggal Village Owned Enterprises in the New Normal Era

This community service program aims to provide assistance in obtaining the legal entity status of BUMKal Agung Manunggal and provide assistance in the form of training and creation of the BUMKal Agung Manunggal Website. This program has five stages of implementation, Stage 1: Observation to identify problems and potentials that can be developed. Stage 2: Program conceptualization is the stage of developing the program to solve successful problems. Stage 3: Program Implementation, aims to carry out training and assistance related to the status of obtaining a legal entity as evidenced by the existence of a legal entity certificate and digital marketing training. Stage 4: Pre Test and Post Test. The results of this implementation show that after mentoring and managing the legal entity BUMKal Agung Manunggal has the status of a legal entity that has been issued by the Ministry of Law and Human Rights of the Republic of Indonesia through the Ministry of Villages of the Republic of Indonesia. Furthermore, the training program and the creation of the Agung Manunggal BUMKal website provide solutions to the limitations of BUMKal

The Effectiveness of Education with Picture Media to Increase Students’ Knowledge and Attitudes about Maintaining the Cleanliness of the External Genitalia at Al-Azhar26 Junior High School Yogyakarta

Background: Cleanliness of women’s genitals is related to the menstrual cycle. The education of menstruation with picture media increases women’s awareness to maintain the cleanliness of the external genital because picture media shows effects of risk behavior if do not maintain the cleanliness. Women with a better understanding of menstruation often have a safe and clean way to manage their menstrual bleeding. Poor knowledge, attitudes and actions towards external genitalia hygiene in adolescent girls have clinical implications, namely the occurrence of infections in the reproductive system and urinary tract infections. In developing countries, this problem needs more serious attention.Objective: This study aims to analyze the effectiveness of education with picture media to increase students’ knowledge and attitudes about maintaining the cleanliness of the external genitalia at Al-Azhar 26 Junior High School Yogyakarta.Methods: This research is a quantitative study with a quasi-experimental design and uses analytic research with a One Group Pretest- Postest Design. In this study there was no control group, data collection using a questionnaire. The population was made up of Grade VIII students of junior high schools who were actively studying at MTs Al- Azhar 26 Yogyakarta. Respondents came from junior high school students because junior high school students represented teenagers and their intellectual abilities were not much different. The research sample was taken by using a total sampling technique of 60 samples. The treatment procedure was after completing the pre-test, students were given education about external genital hygiene with picture media. After receiving education, students were asked to fill out a post test, after the data was collected, data analysis was carried out using the Wilcoxon test. Ethical permission for this research from FKIK UMY with number 106/EC-KEPK FKIK UMY/IV/2021.Results: Respondents are 60, aged 12 and 13 years. The mean value of knowledge before intervention is 7,02, the mean value of knowledge after intervention is 13,68. The mean value of the attitude before the intervention was 15.35, the mean value of the attitude after the intervention was 33.23. The results of the test on the level of knowledge of the respondents using the Wilcoxon test obtained a value of p = 0.001 (p <0.05), this is a significant result in increasing the level of knowledge of respondents about external genitalia hygiene. The results of the test on respondents’ attitudes using the Wilcoxon test obtained p value = 0.001 (p < 0.05), this is a significant result in increasing respondents’ attitudes about the external genitalia.Conclusion: counseling about genital hygiene is effective in increasing knowledge and attitudes about female genitalia in Yogyakarta. Efforts to improve external genital hygiene in adolescents need to be continuously improved with education that is carried out continuously and carried out using various methods.International Journal of Human and Health Sciences Vol. 08 No. 02 Apr’24 Page: 157-164

The effectiveness of acceptance and commitment therapy on the attitude towards marriage and the criteria for choosing a spouse in single students

Aim: This research was conducted with the aim of evaluating the effectiveness of the acceptance and commitment therapy towards marriage and the criteria for choosing a spouse by unmarried students. Methods: This was a pre and post test with a 2 month follow-up. The statistical population of this research included 167 unmarried students of Allameh Tabatabai University who were studying in the academic year of 2020- 2021. The sample were randomly selected and covariance was used for analysis. Findings: The results and findings indicated that the teaching of acceptance-based therapy is effective on the components of attitude towards marriage and the criteria for choosing a spouse in single students. Conclusion: Based on the results of the research, it is suggested that acceptance and commitment therapy could be use in premarital counseling.

A comparison of healthcare utilization and outcomes following skin vs. serum-specific IgE allergy testing

Objective To compare the cost, healthcare utilization, and outcomes between skin and serum-specific IgE (sIgE) allergy testing. Methods This retrospective cohort study used IBM® MarketScan claims data, from which commercially insured individuals who initiated allergy testing between January 1 and December 31, 2018 with at least 12 months of enrollment data before and after index testing date were included. Cost of allergy testing per patient was estimated by testing pattern: skin only, sIgE only, or both. Multivariable linear regression was used to compare healthcare utilization and outcomes, including office visits, allergy and asthma-related prescriptions, and emergency department (ED) and urgent care (UC) visits between skin and sIgE testing at 1-year post testing (α = 0.05). Results The cohort included 168,862 patients, with a mean (SD) age of 30.8 (19.5) years; 100,666 (59.7%) were female. Over half of patients (56.4%, n = 95,179) had skin only testing, followed by 57,291 patients with sIgE only testing and 16,212 patients with both testing. The average cost of allergy testing per person in the first year was $430 (95% CI $426–433) in patients with skin only testing, $187 (95% CI $183–190) in patients with sIgE only testing, and $532 (95% CI $522–542) in patients with both testing. At 1-year follow-up post testing, there were slight increases in allergy and asthma-related prescriptions, and notable decreases in ED visits by 17.0–17.4% and in UC visits by 10.9–12.6% for all groups (all p < 0.01). Patients with sIgE-only testing had 3.2 fewer allergist/immunologist visits than patients with skin-only testing at 1-year follow-up (p < 0.001). Their healthcare utilization and outcomes were otherwise comparable. Conclusions Allergy testing, regardless of the testing method used, is associated with decreases in ED and UC visits at 1-year follow-up. sIgE allergy testing is associated with lower testing cost and fewer allergist/immunologist visits, compared to skin testing.

Public Knowledge About the Use of Toga as Food to Improve Health

Toga is a cultural or maintenance plant that is natural and easy to obtain and easy to grow in the yard of the house. Toga is used as family medicine, one of which can also be used by processing toga as food. The purpose of this study is to find out how public knowledge after being given information about the use of toga as food to improve health. This study used quantitative descriptive method with pre test &amp;; post test data collection. Data was collected through interviews with the community, and supported by documentation. The results of this study stated that public knowledge about the use of toga as food to improve health in Biology subjects on the subject of Biodiversity, Toga as food to improve health that the calculated t value (10.850) with a significant value of 0.000 is greater than 0.05. That is, there is an increase in public knowledge about efforts to improve health through the use of toga as food

An ethical leadership assessment center pilot: Assessing and developing moral person and moral manager dimensions

Abstract Ethical leaders are those who exemplify moral behavior personally, as well as those who facilitate follower ethical behavior. Although recent attention has been given to the ethical leadership construct, there remains a lack of innovation regarding the assessment and development of ethical leaders in organizations. To address these issues, a pilot study was conducted to examine the convergent validity of an ethical leadership assessment center, as well as the efficacy of using assessment center feedback to foster ethical leadership. Assessees completed a battery of pre tests, a virtual business simulation with a novel exercise, and a set of post tests. Half of the assessees were randomly assigned to a feedback condition, whereas the other half did not receive feedback until after the post tests were completed. Due to low statistical power, quantitative results were inconclusive. Nevertheless, qualitative insights were gained that point to implications for validating assessment center methodologies when assessing and developing ethical leadership.

Predictive value of different thresholds of morning cortisol in diagnosing adrenal insufficiency

ObjectiveAdrenal insufficiency (AI) is diagnosed with morning cortisol but ACTH stimulation test is usually needed to confirm the diagnosis. In this study we investigated different morning cortisol thresholds that can safely rule out AI without requiring a confirmatory ACTH stimulation test. DesignRetrospective cohort study. MethodsWe included patients aged 18 and above who underwent the 250 mcg ACTH stimulation test from June 2018 to June 2022. Basal and post-ACTH serum cortisol values at 30 and 60 min were documented. Sensitivity, specificity and logistic regression analysis were employed to assess morning cortisol level's ability to predict AI as confirmed by ACTH stimulation test. Results237 patients were included, 66 diagnosed with AI and 171 had normal ACTH results. Hypertension and type 2 Diabetes correlated with lower AI incidence. Median morning cortisol was 138.0 nmol/L for AI group and 286.0 nmol/L for non-AI patients. A morning cortisol of 285 nmol/L had 90.6 % sensitivity, 50.3 % specificity, and a negative predictive value of 93.3 % for ruling out AI. A threshold of 306 nmol/L increased sensitivity to 95.3 % with 40 % specificity. ConclusionMorning cortisol is an effective diagnostic tool for ruling out AI. Using multiple thresholds based on clinical suspicion and the integration of predictive pre-test probability can reduce the need for excessive ACTH stimulation tests. This study contributes to the growing evidence of utilizing morning serum cortisol in the diagnosis of adrenal insufficiency. Clinical relevance statementDiagnosing Adrenal Insufficiency (AI) can be challenging due to debate regarding the cortisol cut-off value that can exclude AI without additional tests. The confirmatory short synacthen test has certain limitations including financial implications and time restrictions. We investigated the performance of various morning cortisol levels that can diagnose AI without additional testing.

Validity of Umbilical Cord Blood Procalcitonin in the Diagnosis of Early-Onset Neonatal Infection.

Early-onset neonatal infection (EONI) poses significant risks to neonatal health, necessitating reliable diagnostic markers for early detection. This study aims to evaluate the diagnostic validity of procalcitonin (PCT) concentration in umbilical cord blood as a biomarker for EONI. This prospective study was conducted at Ho Chi Minh University Medical Center from April 2022 to September 2022. The PCT level was measured in umbilical cord blood at birth. Based on clinical, laboratory, and microbiologic results, neonates were classified into infected and non-infected groups. One hundred eighty neonates with risk factors for EONI were recruited. Among the neonates studied, 22 (12.2%) were classified as infected and 158 (87.8%) as non-infected by the classification criteria of clinical manifestations, laboratory tests, and blood culture. The median PCT in the infected group was significantly higher than that in the non-infected group (0.389 ng/mL vs. 0.127 ng/mL, p = 0.007). The optimal PCT cut-off was found by receiver operating characteristic (ROC) to be 0.23 ng/mL, with an area under the curve (AUC) of 0.87. The results were 59.1%, 98.7%, 86.2%, 94%, 45, and 0.41 for sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios, respectively. The post-test probability was 86% if the test was positive and 5% if it was negative. Umbilical cord blood PCT might be a reliable marker in the diagnosis of EONI, and its value helps limit the harmful effects of unnecessary prescriptions in non-infected neonates. However, considering the low sensitivity of procalcitonin, further research is necessary to fully integrate this biomarker into clinical practice.

Efektifitas Pemberian Non Nutritive Sucking Terhadap Respon Nyeri Neonatus Pada Pemberian Imunisasi Hb0 Diruang Perinatologi Rs X Husada Malang

Neonatal pain response is an unpleasant experience due to subjective damage to body tissues which can be assessed by facial expressions, body movements, crying and resting using a pain scale. This study aims to determine the effect of Non-Nutritive Sucking on neonatal pain response to HB0 immunization at Wava Husada Malang Hospital. This study used a quasi-experimental post test only control group design. The sample of this study were neonates with a maximum age of less than 24 hours as many as 28 respondents. Using Accidental sampling technique. The independent variable is Non-Nutritive Sucking and the dependent variable is neonatal pain response. Data collection is by taking samples according to the inclusion criteria which are divided into the intervention group and the control group, the data ratio scale. Data analysis used the Mann-Whitney U test (alpha 0.05). The mean response to pain in the control group was higher than the average response to pain in the intervention group. The results of the Mann-Whitney U statistical test obtained a value of Z = -3.90 with a p value = 0.000 which indicated that there was a significant difference in neonatal pain responses in infants during HB0 immunization between the intervention group and the control group.

Using spirometry for screening and diagnosis of chronic respiratory diseases in primary health care: findings from a community health project in rural India

Background Chronic respiratory diseases (CRDs) such as Chronic obstructive pulmonary disease (COPD), Asthma and post-tuberculosis lung disease (PTLD) are a growing public health concern in India. Early diagnosis and management of CRDs require a good quality spirometry test, a technician to conduct spirometry and a chest physician to interpret the results. In India, these are not available at the primary care level. This study reports the feasibility of a large-scale CRD diagnosis and management program in primary care using a unique point-of-care spirometry solution, Briota PFT in a Box™. # Methods A community-based cross-sectional study was conducted among 15,602 adults in Dindori Taluka (subdivision), Nashik, Maharashtra state. This study was part of a holistic CRD diagnosis and management program SAVE™ (Spirometry Assisted Virtually Early). Make In India point of care solution Briota PFT in a Box™ was used. A House‐to‐house community-based assessment checklist (CBAC) survey, 4-parameter spirometry test, 15-parameter pre and post-bronchodilator spirometry test and a software-assisted medical examination by the medical officer at primary care were conducted. Software was used to generate CRD diagnosis and lung health score (LHS™). The diagnosis was verified by the chest physician. Confirmed diagnosed patients were provided treatment and offered a patient support program. Interviews were conducted with the patients, nurses, doctors and public health officials for understanding feasibility and documenting learning from program SAVE™. # Results Out of 15,602 adults surveyed, total 4,937 (31.6%) were identified as “CRD high risk”. 1231 participants based on medical examination, spirometry tests and software analysis were identified as CRD candidates by medical officers at primary care. 1154 participants out of 15,602 (7.4%) were confirmed diagnosed as CRD patients post independent evaluation by chest physicians. At the time of follow-up, 537 patients (75% of 712 patients enrolled in patient support program) reported improvement in symptoms and high satisfaction with the program. District health officer, Medical officers, nurses, Accredited Social Health Activist (ASHA) from the primary health care centers confirmed ease of use and feasibility of using Briota PFT in a Box™ in program SAVE™. Outcome and learning from program SAVE™ was documented and submitted to Ministry of Health and Family Welfare Government of India. # Conclusions CRD diagnosis and management in large scale settings in primary healthcare level using a point of care spirometry solution Briota PFT in a Box™ is highly feasible.

Computed tomography pulmonary angiogram ordering, adherence to decision rules and yield in the emergency department: An observational study.

Pulmonary embolism (PE) frequently requires diagnosis through CT pulmonary angiogram (CTPA). Appropriate application of evidence-based clinical decision tools can reduce unnecessary CTPAs. This study assessed adherence to and the efficacy of various aspects of the Queensland Health suspected PE diagnostic pathway, including Wells score, PE rule out criteria (PERC) and age-adjusted D-dimer interpretation. Retrospective study of CTPAs ordered from 1 January to 30 April 2023 in a tertiary and urban ED in Southeast Queensland. Data on clinical variables, D-dimer and CTPA results were collected through medical record and radiology database review. Descriptive analyses were used to determine adherence to Queensland guidelines and performance of D-dimer interpretation tools (including comparison of age-adjusted PE with a new pre-test probability [PTP]-based model using D-dimer cut-off <1000 ng/mL for Wells score ≤4 and 500 ng/mL for Wells score 4.5-6). A total of 573 CTPAs were available for analysis with a 12.4% (95% confidence interval 10.0-15.4) diagnostic yield. Stratification by Wells score showed yields of 4.0%, 18.5% and 41% for low-, moderate- and high-risk patients, respectively. Twenty-five patients with low-PTP who received CTPA could have been excluded with the PERC rule. Age-adjusted D-dimer interpretation may have prevented 26 CTPAs with no false negatives, whereas PTP approach may have prevented 128 CTPAs with four false negatives. Guideline adherence can be improved, and adherence to existing clinical decision tools may reduce unnecessary CTPA ordering and increase diagnostic yield. The use of the age-adjusted D-dimer had good sensitivity, whereas the new PTP approach will require further prospective research.

Coronary calcifications as assessed on routine non-gated chest CT; a gatekeeper to tailor downstream additional imaging in patients with stable chest pain

Background and aimsCurrently applied methods for risk-assessment in coronary artery disease (CAD) often overestimate patients’ risk for obstructive CAD. To enhance risk estimation, assessment of coronary artery calcium (CAC) can be applied. In 10 % of patients presenting with stable chest pain a previous non-gated computed tomography (CT) has been performed, suitable for CAC-assessment. This study is the first to investigate the clinical utility of CAC-assessment on non-gated CT for risk-assessment of obstructive CAD in symptomatic patients. MethodsFor this analysis, all patients referred for coronary computed tomography angiography (CCTA), in whom a previous non-gated chest CT was performed were included. The extent of CAC was assessed on chest CT and ordinally scored. CAD was assessed on CCTA and obstructive CAD defined as stenosis of ≥70 %. Patients were stratified according to CAC-severity and percentages of patients with obstructive CAD were compared between the CAC groups. ResultsIn total, 170 patients of 32–88 years were included and 35 % were male. The percentage of obstructive CAD between the CAC groups differed significantly (p < 0.01). A calcium score of 0 ruled out obstructive CAD irrespective of sex, pre-test probability, type of complaints and number of risk factors with a 100 % certainty. Furthermore, a mild CAC score ruled out obstructive CAD in patients with low – intermediate PTP or non-anginal complaints with 100 % certainty. ConclusionWhen available, CAC on non-gated chest CT can accurately rule out obstructive CAD and can therefore function as a radiation-free and cost-free gatekeeper for additional imaging in patients presenting with stable chest pain.

The Effect of Soaking Feet in Warm Water on the Quality of Sleep in Adolescents

Background: adolescence is a transitional period where individuals experience physical changes and psychological development starting at the age of 12-20 years. These changes can cause problems that affect development, health and sleep quality. To improve sleep quality, foot bath in warm water Objective: to determine the effect of foot bath in warm water on the quality of sleep in adolescents. Research design: two group pre and post test. Research subject: there were 30 students from the Department of Physiotherapy, Health Polytechnic, Surakarta, who were divided into two groups, where group one was given intervention for 7 consecutive days and the research instrument used PSQI. Research result : the independent t-test showed that there was an influence on adolescent sleep quality. Conclusion : foot bath in warm water has an effect on improving the quality of sleep in adolescents.

Validation of the European Society of Cardiology pretest probability models for obstructive coronary artery disease in high-risk population

BackgroundThe pre-test probability (PTP) model for obstructive coronary artery disease (CAD) was updated in 2019 by the European Society of Cardiology (ESC). To our knowledge, this model was never externally validated in population with high incidence of CAD. The aim of this study is to validate the new PTP ESC model in our population which has a high CAD incidence and to compare it with previous PTP ESC model from 2013. MethodsWe retrospectively analysed 1294 symptomatic patients with suspected CAD referred to our centre between 2015 and 2019. In all patients, the PTP score was calculated based on age, gender and symptoms according to the ESC model from 2013 (2013-ESC-PTP) and 2019 (2019-ESC-PTP). All patients underwent invasive coronary angiography (ICA). ResultsOf the 1294 patients, obstructive CAD was diagnosed in 533 patients (41.2%). The 2019-ESC-PTP model categorised significantly more patients into the low probability group (PTP < 15%) than the 2013-ESC-PTP model (39.8% vs. 5.6%, P< 0.001). Obstructive CAD prevalence was underestimated using 2019-ESC-PTP at all PTP levels (calibration intercept 1.15, calibration slope 0.96). The 2013-ESC-PTP overestimated obstructive CAD prevalence (calibration intercept -0.24, calibration slope 0.73). The discrimination measured with an area under the curve was similar for both models, indicating moderate accuracy of the models. ConclusionsIn high-risk Serbian population, both the 2013 and 2019 ESC-PTP models had moderate accuracy in diagnosing CAD, with the 2019-ESC-PTP underestimating the prevalence of CAD, while the 2013-ESC-PTP overestimating it. Further studies are warranted to establish PTP models for high-risk countries.

Extracorporeal Shock Wave Therapy as Regenerative Medicine in Knee Osteoarthritis: Pre-Experiment for Matrix Metalloproteinase-3 Evaluation.

Knee osteoarthritis (KOA) is currently treated by regenerative therapies that aim to inhibit arthritic degeneration. Extracorporeal shock wave therapy (ESWT) is one of the physical regenerative approaches used for KOA management. However, little is known regarding the impact of shock wave treatment on matrix metalloproteinase-3 (MMP-3), which is one of the enzymes mediating cartilage degradation. To evaluate the effect of ESWT on MMP-3 levels and pain intensity in patients with KOA. Fourteen patients diagnosed with Kellgren Lawrence, grades 2 and 3 KOA were recruited for the study. ESWT piezo shockwave was applied once a week for six weeks. MMP-3 levels in the blood were measured pre-test, mid-test (three weeks after therapy) and post-test (one week after the last session) by enzyme-linked immunosorbent assay (ELISA). The perceived pain was recorded at each session by the Wong Becker Face Scale. The median pre-test, mid-test and post-test MMP-3 levels were 19.92 ng/mL, 15.89 ng/mL and 18.82 ng/mL, respectively, and there were significant differences between the pre-test and mid-test, and the pre-test and post-test values (p < 0.05). The pain scores also decreased significantly over the period of intervention. MMP-3 levels decreased significantly in KOA patients after ESWT, and the decline was most obvious after 3 weeks of therapy. Therefore, EWST should be considered as a suitable treatment option for KOA.