We would like to make some comments about managing cardiopulmonary arrest in pregnant women as it is described in the guidelines of Resuscitation 2000;46:293–5 [[1]Special issue. International Guidelines 2000 for CPR and ECC—A Consensus on Science. Resuscitation 2000;46:293–5.Google Scholar]. The International 2000 guideline states that it is not advisable to resuscitate a pregnant woman lying on her back because the gravid uterus may obstruct venous return via the inferior vena cava and therefore chest compression is more less likely to be effective. Indeed, studies confirm that applying a partial left lateral tilt to the patient will relieve the aorto-caval compression [[2]Johnson MD, et al. Cardiopulmonary resuscitation. In: Gambling DR, Douglas MJ, editors. Obstetric anaesthesia and uncommon disorders. Philadelphia: WB Saunders; 1998. p. 51–74.Google Scholar]. Rees and Willis [[3]Rees G.A.D Willis B.A Resuscitation in late pregnancy.Anaesthesia. 1988; 43: 347-349Crossref PubMed Scopus (127) Google Scholar] conclude that the best compromise for cardiopulmonary resuscitation (CPR) is achieved by wedging the patient at an angle of 27°. However at this angle there is a disadvantage in that the rescuer can provide only 80% of the transmitted external resuscitative force. Because the transmission forces during external CPR in this position are not perpendicular to the thorax and a part of the transmitted force is lost, left lateral positioning for CPR is not ideal. Overturned chairs and positioning the patient in the full lateral position as shown in Fig. 1, page 294 of the International resuscitation guidelines 2000 [[1]Special issue. International Guidelines 2000 for CPR and ECC—A Consensus on Science. Resuscitation 2000;46:293–5.Google Scholar] make external CPR impossible [[3]Rees G.A.D Willis B.A Resuscitation in late pregnancy.Anaesthesia. 1988; 43: 347-349Crossref PubMed Scopus (127) Google Scholar]. Because chest compression are more effective in the supine position than in the left lateral wedge position, the best compromise for CPR and optimal venous return is in the supine position with manual displacement of the uterus to the left as recommended by Johnson et al. [[2]Johnson MD, et al. Cardiopulmonary resuscitation. In: Gambling DR, Douglas MJ, editors. Obstetric anaesthesia and uncommon disorders. Philadelphia: WB Saunders; 1998. p. 51–74.Google Scholar]. The guidelines indicate no changes to the standard algorithms for medication, intubation and defibrillation. However intubation is more difficult and defibrillation is different compared to the non-pregnant cardiac-arrest situation. As pregnant women present dextroversion of the heart, one paddle should be placed below the right clavicle in the midclavicular line while the second paddle should be placed outside the normal cardiac apex avoiding breast tissue [[4]Luppi C.J Cardiopulmonary resuscitation: pregnant women are different.AACN Clin Issues. 1997; 8: 574-585Crossref PubMed Scopus (18) Google Scholar]. Also, the timing of emergency caesarean section is open to criticism. Understandably, the discussion is not easy. In the International Guidelines 2000 on pages 294 and 295 [[1]Special issue. International Guidelines 2000 for CPR and ECC—A Consensus on Science. Resuscitation 2000;46:293–5.Google Scholar] it is recommended to attempt basic life support (BLS) first and only to proceed with emergency caesarean section if advanced measures have been commenced already and the problems are not immediately reversible. But hesitation punishes the pregnant patient and guidelines do not give clear guidance when emergency caesarean section should be started during the algorithm. The guideline on page 294 suggests that after BLS and advanced life support (ALS) have failed, and if there is some chance that the fetus is viable, immediate perimortem caesarean section has to be considered. This can be confusing for medical personnel unfamiliar with the difficulties of parturient cardiac arrest. Even if the fetus is not viable emergency cesarean section is required in order to improve venous return and consequently the cardiac output during CPR. Following delivery of the fetus cardiac output in non cardiac arrest patients can increase up to 80% above predelivery values [[5]Ueland K Hansen J.M Maternal cardiovascular dynamics 3. Labor and delivery under local and caudal analgesia.Am. J. Obstet. Gynecol. 1969; 103: 8-18Abstract Full Text PDF PubMed Scopus (138) Google Scholar]. Because maternal brain damage is likely after 4 min of sustained cardiac arrest [6American Heart Association. Textbook of advanced cardiac life support. Dallas: AHA; 1987.Google Scholar, 7Archer G.W Marx G.F Arterial oxygen tension during apnoea in parturient women.Br. J. Anaesth. 1974; 46: 358-360Crossref PubMed Scopus (122) Google Scholar] and may be irreversible after 6 min [[8]Weber C.E Postmortem cesarean section: review of the literature and case reports.Am. J. Obstet. Gynecol. 1971; 110: 158-165PubMed Scopus (49) Google Scholar] perimortem cesarean section should be considered at the fourth minute of cardiac arrest. It should be mentioned that, after perimortem delivery, 10 units of oxytocin should be injected in the myometrium to prevent uterine bleeding. Also, if external chest compressions are unsuccessful after 15 min open cardiac message should be considered (Johnson et al. 1998).