Posterior Hyperplastic Primary Vitreous Research Articles

Cataract surgery in infants with microphthalmos.

To report the postoperative outcomes of cataract surgery in microphthalmic eyes of infants. This prospective observational study was carried out on 20 infants with microphthalmos with visually significant cataract. Microphthalmos was defined as axial length of the globe 16.50 mm or less. We excluded eyes with ocular trauma, inflammation, posterior hyperplastic primary vitreous or a tractional retinal detachment, aniridia, or chorioretinal coloboma. All the infants enrolled in this study underwent phacoaspiration with primary posterior capsulotomy, anterior vitrectomy, and peripheral iridectomy. Intraocular lens was not implanted in these children. Post-operative evaluation included refractive errors, irregularity of pupil, posterior synechiae, visual axis obscuration, and intraocular pressure. These children were followed up for a minimum of 12 months. We evaluated 37 eyes of 20 infants, of whom 17 infants had bilateral and three infants had unilateral cataract. The mean age of the children and the mean axial length at the time of surgery were 3.78 ± 2.25 months and 15.76 ± 0.56 mm respectively. The complications observed were irregularity of pupil in seven eyes (18.9 %), glaucoma in five eyes (13.5 %), posterior synechiae in two eyes (5.2 %), visual axis obscuration due to posterior capsule opacification (PCO) in two eyes (5.2 %) and phthisis in one eye (2.7 %). Infants achieved a favorable outcome after phacoaspiration with primary posterior capsulotomy with anterior vitrectomy. However, these children must be followed up to detect and treat postoperative complications such as visual axis obscuration, posterior synechiae, and glaucoma to achieve optimal outcome.

Use of the ocutome in anterior segment surgery.

9 patients are presented on whom anterior vitrectomy was performed. The indications included congenital rubella cataract with microphthalmos, traumatic cataract, persistent anterior and posterior hyperplastic primary vitreous, postcataract pupillary membranes, and postcataract vitreous prolapse with cystoid mascular edema. All patients to date have responded satisfactorily to the procedure. There has been no incidence of complicating retinal detachment.

Posterior hyperplastic primary vitreous.

A fundus picture of posterior hyperplastic primary vitreous based on a study of 14 cases is described. Its definition, in spite of pleomorphic manifestations, could be useful for its differentiation from other conditions affecting children's eyes and presumed to be caused by parasitic, inflammatory, fibroplastic, or genetically transmitted processes.

The Pleomorphism and Complications of Posterior Hyperplastic Primary Vitreous

Among 30 patients examined, posterior hyperplastic primary vitreous was monocular in 25 and binocular in five. Poor vision and strabismus were the most common presenting complaints. All patients had vitreous membranes usually extending from the disk toward the equatorial zone. In 70% of the affected eyes, the vitreous membranes were associated with a radial retinal fold. Macular function was disturbed in 70% and retinal detachment was observed in 45% of the eyes. One extensive retinal detachment was successfully treated by scleral buckling; another detachment, limited to the posterior pole, responded to sectioning of a vitreous band with scissors.

Posterior Hyperplastic Primary Vitreous

Congenital retinal fold (congenital retinal septum, ablatio falciformis congenita) is a rare occurrence and is frequently misdiagnosed. Often it is only one of a group of ocular anomalies which appear to result from a posterior form of persistent or hyperplastic primary vitreous. This report presents our findings in a se­ ries of patients with this syndrome, reviews current theories of pathogenesis, and com­ ments on the clinical significance of abnor­ mal vitreoretinal development.