Postpartum Females Research Articles

Postpartum thromboprophylaxis with enoxaparin: a prospective cohort study on patients' adherence, injection experience, and information retention after counselling by pharmacists.

This research aimed to determine postpartum females' self-reported adherence to and experience with short-term thromboprophylaxis using enoxaparin injection, after counselling by pharmacists. It also sought to assess their knowledge of thromboprophylaxis, injection techniques, and confidence in self-injecting. This prospective cohort study was conducted at a public tertiary hospital in Malaysia from March to June 2023. Self-injection-naïve postpartum females who were initiated on thromboprophylaxis and counselled by a pharmacist were conveniently sampled. Knowledge regarding thromboprophylaxis, injection readiness, and technique were assessed one day after the counselling session. A telephonic interview was conducted at the end of the 10-day therapy to determine adherence and adverse effects experienced. A total of 259 subjects were successfully followed up, with 87.6% (n = 227) adherent to the therapy. Nonadherence was predominantly due to forgetfulness; four had their treatment withheld due to bleeding. One-third of subjects experienced localised pain and bruising. Subjects answered a median of 5/7 knowledge questions and recalled a median of 8/10 injection steps correctly, with those who read the information leaflet provided after counselling scoring significantly higher (P = .02). The majority declared moderate confidence in their ability to self-inject. Subjects who intended to self-inject (P < .01) and were more confident (P = .02) demonstrated better injection technique. Postpartum females counselled by pharmacists largely adhered to short-term enoxaparin for thromboprophylaxis. The impact of the counselling session may be enhanced by addressing their psychological readiness to self-inject, awareness of adverse effects identification, mitigation, and management, as well as setting reminders to prevent forgetfulness to inject.

Effects of Intermittent Harem Mating on Parturition-induced Stress and Success Rate of Weaning in C57BL/6JNarl Mice.

Improving the effectiveness of mating schemes for large-scale production of mice is an ongoing challenge in animal facilities. Continuous mating, which requires fewer breeding cages than intermittent mating, has traditionally been used to take advantage of postpartum estrus for efficient production. However, the continuous mating scheme lacks flexibility because it cannot immediately accommodate the reduced needs of mice when production levels are high. In this study, we compared reproductive performance, fecal corticosterone metabolite (FCM) level as a stress indicator, and mouse mortality between the continuous trio (CT) and intermittent quad (IQ) mating schemes. The weaning rates in the IQ scheme were higher than those in the CT scheme (98.8% compared with 85.3%). The FCM levels in IQ female breeders were lower during the first 5 d after parturition than those in CT female breeders. The FCM levels in postpartum females housed with 2 adult mice were significantly higher on days 1, 3, and 5 after giving birth than those of females housed alone. This suggests that the presence of cage mates may induce stress responses in postpartum females. Increasing the individual cage area did not reduce the FCM levels of female breeders when accompanied by cage mates after parturition. In addition, the incidence of dystocia and mortality was lower in IQ breeders than in CT breeders. In summary, this breeding trial suggests that compared with the continuous mating scheme, the intermittent mating scheme improves the welfare of postpartum females with normal breeding performance in the C57BL/6JNarl production colony.

Relationship between childhood trauma and postpartum psychotic experiences: the role of postnatal anxiety and depression as mediators

BackgroundPostpartum psychosis (PP) is a psychological emergency requiring rapid intervention, hospitalization and psychiatric management. However, PP has been neglected in the postpartum literature. Understanding the detrimental consequences of childhood trauma across mother’s life span is crucial to prevent this serious condition. The study’s objectives were to demonstrate the relationship between childhood trauma and postpartum psychotic experiences (PPEs) and to look over the mediating role of postnatal depression (PD) and anxiety (PA) in this relationship.MethodsThis cross-sectional study, which enrolled 438 postpartum females 4–6 weeks after delivery (mean age: 31.23 ± 5.24 years), was carried out from September 2022 to June 2023. The Arabic validated versions of the Postpartum Psychotic Experiences Scale, the Edinburgh Postnatal Depression Scale, the Perinatal Anxiety Screening Scale, and the Child Abuse Self Report Scale were used.ResultsBoth PD and PA partially mediated the correlation between psychological abuse and PPEs, and fully mediated the association between neglect and PPEs. Higher psychological abuse and neglect were significantly associated with higher PD (Beta = 1.11) and PA (Beta = 3.94), higher PD (Beta = 0.84) and PA (Beta = 0.26) were significantly associated with higher PPEs in both models, whereas greater child psychological abuse (Beta = 1.37) (but not neglect) was directly and strongly correlated with higher PPEs in all models.ConclusionThe significant mediating effect of PA and PD on the association between childhood adversities and PPEs among postpartum females may offer additional therapeutic avenues to help attenuate various postpartum mental health issues and their potential serious risks on both mother and child.

Effects of Soft Tissue Mobilization Versus Myofascial Release Technique on Low Back Pain and Disability in Post-Partum Females After Caesarean Section

Background: Postpartum females who undergo cesarean section often experience low back pain (LBP) and disability. Effective management of these symptoms is crucial for enhancing recovery and quality of life.Objective: To evaluate and compare the effects of soft tissue mobilization (STM) and myofascial release therapy (MFR) on LBP and disability in postpartum females after cesarean section.Methods: A randomized clinical trial was conducted with 24 postpartum females who underwent cesarean sections. Participants were randomly assigned to two groups: Group A received STM, and Group B received MFR. Both interventions were administered twice weekly for three weeks. Pain and disability were assessed at baseline, six weeks, and twelve weeks post-intervention using the Numeric Pain Rating Scale (NPRS) and Oswestry Disability Index (ODI). Data were analyzed using SPSS version 25, with significance set at p &lt; 0.05.Results: Group B (MFR) demonstrated a significantly greater reduction in NPRS scores (1.09 ± 1.04) and ODI scores (6.54 ± 7.70) compared to Group A (STM) with NPRS scores (4.27 ± 0.90) and ODI scores (22.36 ± 12.20) (p &lt; 0.05).Conclusion: MFR was more effective than STM in reducing LBP and disability in postpartum females following cesarean section.

Takotsubo Syndrome: Differences between Peripartum Period and General Population.

Takotsubo syndrome (TTS) was first described in postmenopausal women with transient regional wall motion abnormalities. The trigger is usually an emotional or physical stress. The catecholamine hypothesis seems to be the most prevailing. The main difference between TTS and acute coronary syndromes is that there is no obstructive coronary disease to explain the regional abnormalities. In this form, the left ventricle resembles the fishing jar which is used to trap octopus in Japan. However, to date more atypical forms are recognized. Also, the syndrome is not limited to older women. Nowadays, TTS is presented even in pregnancy and postpartum females. Our experience revealed cases of patients during these periods and some of them suffered from reverse Takotsubo. Additionally, the initial diagnosis in some patients was other than TTS. Due to these findings, we suggest that this type of TTS is not very rare but underestimated. For this reason, further studies are needed to support and explain this condition.

Presence of fetal microchimerisms in the heart and effect on cardiac repair.

Multiple complex biological processes take place during pregnancy, including the migration of fetal cells to maternal circulation and their subsequent engraftment in maternal tissues, where they form microchimerisms. Fetal microchimerisms have been identified in several tissues; nevertheless, their functional role remains largely unknown. Different reports suggest these cells contribute to tissue repair and modulate the immune response, but they have also been associated with pre-eclampsia and tumor formation. In the maternal heart, cells of fetal origin can contribute to different cell lineages after myocardial infarction. However, the functional role of these cells and their effect on cardiac function and repair are unknown. In this work, we found that microchimerisms of fetal origin are present in the maternal circulation and graft in the heart. To determine their functional role, WT female mice were crossed with male mice expressing the diphtheria toxin (DT) receptor. Mothers were treated with DT to eliminate microchimerisms and the response to myocardial infarction was investigated. We found that removal of microchimerisms improved cardiac contraction in postpartum and post-infarction model females compared to untreated mice, where DT administration had no significant effects. These results suggest that microchimerisms play a detrimental role in the mother following myocardial infarction.

The Effectiveness of Physical Therapy Interventions in Management of Diastasis Recti in Postpartum Females: A Narrative Review

Diastasis recti is a condition caused by increased intra-abdominal pressure which causes the linea alba to stretch resulting in a wider inter-rectus gap. It is most common after pregnancy but can also be caused by obesity or previous abdominal procedures. Research shows myofascial laxity affecting the entire front abdominal wall. Postpartum women have a doubling of the interrectus distance and pregnancy affects abdominal muscle strength with nulliparous women having a higher number of trunk flexors and rotators [1]. DRA is mostly treated conservatively. Patients referred to a physiotherapist receive training programmes that specifically target reducing IRD. Some studies recommend training with physiotherapist, while others let patients train on their own. Recommended frequency of training sessions varied from one to five sessions per week. The exercise interventions consist of the following: Core trainings, Breathing technique and Mindfulness teaching. This study aims to find out the effectiveness of different physical therapy interventions in the treatment of diastasis recti abdominis. The condition of diastasis recti abdominis has prevalence in postpartum females and it is important to address this for the welfare of women and required to explore the best physical therapy treatment available.

Noradrenergic Regulation of the Medial Prefrontal Cortex Mediates Stress Coping in Postpartum Female Mice.

The prevalence of depression in women increases during the postpartum period. We previously reported that subchronic exposure to social stress decreased passive coping in postpartum female mice. This study aimed to investigate whether noradrenaline regulation might regulate coping styles in mice. We first determined whether a different type of stress, subchronic physical stress, decreases passive coping in postpartum females. Postpartum female, virgin female, and male mice were exposed to subchronic restraint stress (restraint stress for 4h for 5 consecutive days). Subchronic restraint stress decreased passive coping in postpartum females but not in virgin females and males in the forced swim and tail suspension tests. We next examined the neuronal mechanism by which subchronic stress decreases passive coping in postpartum female mice. Neuronal activity and expression of noradrenergic receptors in the medial prefrontal cortex (mPFC) were analyzed using immunohistochemistry and reverse transcription-quantitative polymerase chain reaction, respectively. The mPFC was manipulated using chemogenetics, knockdown, or an α2A adrenergic receptor (AR) antagonist. Immunohistochemistry revealed that subchronic restraint stress increased glutamatergic neuron activation in the mPFC via forced swim stress and decreased α2A AR expression in postpartum females. Chemogenetic activation of glutamatergic neurons in the mPFC, knockdown of α2AAR in the mPFC, and the α2A AR receptor antagonist atipamezole treatment decreased passive coping in postpartum females. Subchronic restraint stress decreased passive coping in postpartum females by increasing glutamatergic neuron activity in the mPFC through α2A AR attenuation. The noradrenergic regulation of the mPFC may be a new target for treating postpartum depression.

Association of Breast-Feeding Positions with Scapular Dyskinesia in Postpartum Females

Background: Breastfeeding is a vital activity for the nurturing and development of infants. However, the postures adopted during breastfeeding may have implications for the physical well-being of postpartum females, particularly concerning scapular dyskinesia—a condition characterized by altered scapular movement and positioning, which can affect shoulder function. Objective: This study aimed to investigate the association between different breastfeeding positions and the prevalence of scapular dyskinesia among postpartum females, providing insights into the potential musculoskeletal implications of breastfeeding practices. Methods: An observational cross-sectional study was conducted involving 111 postpartum females aged 18-45 years, who had been breastfeeding for six months or more. Participants were recruited using non-probability convenient sampling from various hospitals in Lahore, Pakistan. Data on breastfeeding positions and the occurrence of scapular dyskinesia were collected through self-administered questionnaires and the Scapular Dyskinesia Test (SDT) by McClure, respectively. Descriptive statistics were used to summarize participant demographics and breastfeeding practices, while the chi-square test was employed to examine the association between breastfeeding positions and scapular dyskinesia. Results: Among the participants, the cradle hold was the most commonly used breastfeeding position (82.0%), followed by the cross cradle (13.5%), side-lying (3.6%), and laid-back positions (0.9%). The prevalence of scapular dyskinesia was 41.4%, with no statistically significant association found between breastfeeding positions and scapular dyskinesia (p-value = 0.06). Additionally, upper back pain was reported by 39.6% of the participants, indicating a notable presence of musculoskeletal discomfort. Conclusion: The study concluded that there is no significant association between breastfeeding positions and scapular dyskinesia among postpartum females. Despite the high prevalence of scapular dyskinesia and musculoskeletal discomfort, the type of breastfeeding position does not appear to influence the likelihood of developing scapular dyskinesia. These findings suggest the need for further research into the factors contributing to musculoskeletal health in postpartum females and the development of guidelines for breastfeeding practices that promote maternal comfort and physical well-being.

Spontaneous bladder rupture: a case report of a rare complication of normal vaginal delivery

Background: Spontaneous bladder rupture (SBR) is defined as the presence of rupture without any antecedent trauma. It is usually due to underlying bladder pathology. Bladder rupture during labor or the postpartum period is extremely rare. Case Presentation: A 29-year-old gravida 2 Para 1 + 0 had an uneventful labor and a vacuum was used to assist the delivery. Seven days later, she was presented to the emergency department (ED) complaining of inability to urinate and abdominal pain. An immediate ultrasound scan (US) showed free fluid in the abdomen and pelvis. Due to her unstable condition, she was admitted to the ICU. The diagnosis of bladder rupture was made based on a CT cystogram showing contrast leaking from the posterior surface of the dome of the bladder. The patient was successfully managed conservatively by indwelling Foley&amp;apos;s catheter and peritoneal drainage. Conclusion: Post-partum females with an acute abdomen associated with anuria, high blood urea nitrogen (BUN), and elevated serum creatinine should be investigated and treated emergently as SBR. Conservative management might be a successful option under the right conditions for the treatment of intra-peritoneal bladder rupture.

Evaluation of pregnancy associated glycoproteins assays for on farm determination of pregnancy status in beef cattle.

Transrectal ultrasonography is known as the gold standard for pregnancy detection, but requires costly equipment and technical skills; therefore, access to an inexpensive and more user-friendly method with similar accuracy could benefit cattle producers. Detection of pregnancy-associated glycoproteins can accurately determine pregnancy in ruminants; however, usually requires specialized equipment for the assay. Thus, the objectives of these studies were to 1) validate the IDEXX Alertys OnFarm Pregnancy Test (lateral flow) and compare the accuracy of all three commercial PAG assays to transrectal ultrasonography and 2) to determine the postpartum interval necessary for clearance of pregnancy-associated glycoproteins from the previous pregnancy to avoid false positives. In study 1, blood samples from previously identified pregnant Bos taurus females from six different herds (nulliparous n = 1,205 and multiparous n = 1,539; samples collected between d 27 to 285 of gestation over a three-year period) were utilized. In study 2, postpartum females (primiparous n = 48 and multiparous n = 66) from one herd were utilized: (n = 1,066; samples collected weekly for up to 12 weeks postpartum). In study 1, level of agreement between different methods of pregnancy detection was determined by Pearson's correlation and Kappa scores. In study 2, data were analyzed as a repeated measure using the MIXED procedure of SAS with main effects of parity, days postpartum (dpp), and parity by days postpartum, then data were analyzed further using the REG procedure of SAS. In study 1, transrectal ultrasonography and lateral flow were positively correlated (r = 0.77; P <0.01), with 92.4% agreement. In study 2, the abundance of absorbance of PAGs rapidly decreased from 0 to 50 days postpartum, then continued to gradually decrease (P <0.01; r = 0.90). Prior to 42 days postpartum, PAG concentrations were sufficiently elevated resulting in false positive readings in all assays. In conclusion, there is very good agreement between transrectal ultrasonography and PAG assays, but likelihood of false positive results are highif assays are performed fewer than 42 days postpartum.

Exercise for the Treatment of Postpartum Lumbopelvic Pain: A Critically Appraised Topic

Focused Clinical Question: In individuals reporting low back pain postpartum, is exercise an effective intervention to reduce symptoms? Clinical Bottom Line: There is moderate evidence to support the use of an exercise intervention to reduce pain and improve functional disability in postpartum females with low back pain.

A Comparative Study of Knee Joint Proprioception Assessment in 12-Week Postpartum Women and Nulliparous Women.

Introduction Proprioception is one's capacity to perceive bodily position, alignment, and movement. Several connective tissues, such as skin, ligaments, joint capsules, and muscles in the body, contain proprioceptive sensory receptors. Joint elasticity results from hormonal variations, notably the peak relaxin hormone during pregnancy, which also affects proprioceptive receptors. The musculoskeletal system may be affected by hormones and anatomical changes brought on by pregnancy, including joint laxity and modifications to posture and gait. The capacity to perceive the joint position and movement, or proprioception, may be impacted. To comprehend the impacts of pregnancy on joint function and postpartum women's rehabilitation options, this study compares knee joint proprioception in women who gave birth 12 weeks ago to nulliparous women. The study aims to assess and compare the degree of alteration in knee joint proprioception in 12-week postpartum females. Methodology A total of 160 participants were assessed during the entire study. Women from 18 to 35 years of age were included in the study. Women with any present knee joint injury, multiparty, or relevant surgical history were excluded. The procedure was performed under the author's surveillance at the Department of Community Health Physiotherapy. The knee joint reposition test was used to assess the knee joint proprioceptive error among two groups (80 each), including nulliparous women and the other 12-week postpartum women. Animage tool provided by the University of Texas Health Science Centre at San Antonio (UTHSCSA) was created and offers thetool as computer software or a digital application for handling medical pictures and associated data, software 3.0 was used to determine the angular variation between angles in the targeted and achieved positions during the test. Result A significant proprioceptive error was observed among 12-week postpartum women compared to the nulliparous group of women. The mean error of knee joint repositions among 12-week postpartum womenwas 0.80±6.08 (P=0.0001), and among nulliparous womenwas 0.09±0.72 (P=0.0001). Conclusion Concludinginsight that pregnancy affects postpartum women's risk of fall injuries and joint function due to altered proprioception. Compared to nulliparous women, proprioceptive error for the dominant knee joint was significant among 12-week postpartum females. The hormonal changes during pregnancy affect the proprioceptive receptors, especially the relaxin hormone surge, which results in joint laxity and may impair joint position sensing, increasing the risk of falls. To better acknowledge the effects of pregnancy on joint function and postpartum women's rehabilitation options, this study compares knee joint proprioception in postpartum and nulliparous women. It proves right about altered proprioception post-childbirth. The results of this study might aid medical practitioners in creating successful rehabilitation plans and treatments to stop postpartum women from falling.

Improving Quality of Life in Postpartum Females by Non-invasive Pelvic Floor and Abdominal HIFEM and Synchronized Radiofrequency Treatments for Strengthening Core Muscles

Improving Quality of Life in Postpartum Females by Non-invasive Pelvic Floor and Abdominal HIFEM and Synchronized Radiofrequency Treatments for Strengthening Core Muscles

Effects of Core Stabilization Exercises and High-Velocity Thrust Manipulation on Pelvic-Girdle Pain: A Randomized Controlled Trial

Pelvic-girdle pain is a mechanical disorder is very prevalent that leads the individual to suffer with disability and functional limitations. Objective: To determine the effectiveness of core stabilization exercises with thrust manipulation (HVT) on pelvic girdle pain in postpartum women. Methods: This randomized, placebo treatment-controlled trial was conducted in Physiotherapy OPD clinic in Jinnah Memorial Trust Hospital Gujranwala, Pakistan. We included 40 post-partum females consecutively aged 18 to 45 years presenting with pelvic girdle pain for over the past 6 to 16 months of the delivery meeting were isolated in two groups using convenient sampling. The control group received stabilization exercises with routine physical therapy treatment and the treatment group received a high velocity thrust manipulations technique (HVTT). The study instruments included Oswestry Disability Index Questionnaire and numeric pain rating scale. Data were analysed using SPSS 21.0. Results: The findings indicated demographics age with a mean and S.D score of 31.08 ± 6.36. In participants pain numeric pain and ODI scores in the post-treatment group were significant with a p &lt;0.01 and general exercise with a p&lt;0.02. The pre and post ODI scores in both groups had a p-value &lt;0.05 except the within-group score of p &gt;0.068. Conclusions: The application of high velocity thrust manipulation is effective approach in reducing pelvic girdle pain and discomfort in postpartum women. The HVTT treatment therapy can be deemed superior to core stabilization exercises.

A Scoping Review of the Apparent Phenomenon of the Improvement in Hypoparathyroidism in Pregnant and Postpartum Females.

Hypoparathyroidism requires management with both calcium supplementation and active vitamin D to avert a state of hypocalcemia. During late gestation and the postpartum period (specifically lactation), there is an under-recognized, yet intriguing occurrence of apparent 'pseudohyperparathyroidism', whereby supplementation dosages may need to either be reduced or discontinued, to prevent hypercalcemia. The explanation for this apparent phenomenon of improved parathyroid status ('remission' or 'resolution') is incompletely understood; the purpose of this review is to analyze the case reports of this enigma within the medical (and grey) literature, providing an overall pathophysiological explanation and recommendation for the management of such patients. A literature search was conducted through PubMed/Medline, CINAHL, Cochrane Library Database, Scopus, UpToDate, Google Scholar, and the grey literature without a time-restricted period, analyzing all available articles within the literature describing an apparent improvement in parathyroid status in late-gestation and postpartum (lactating) females. Non-hypoparathyroid case reports were also included to further analyze and synthesize an overall likely pathophysiological explanation. Through the literature search, 24 papers were identified covering such a phenomenon in patients with hypoparathyroidism, alongside multiple additional reports of a similar occurrence in patients without underlying hypoparathyroidism. The pathophysiology is believed to occur due to the placental production of parathyroid hormone-related peptide (PTHrP) during gestation, with further production from the lactating mammary glands during the postpartum period. A typical pattern is observed, with increased PTHrP and suppressed PTH throughout both gestation and lactation (present in both normal and hypoparathyroid subjects). The concept of PTHrP-induced hypercalcemia is further demonstrated in patients without hypoparathyroidism, including subjects with placental hypersecretion and mammary gland enlargement. It is evident that patients with hypoparathyroidism may require a dosage reduction during late gestation and lactation, due to the risk for hypercalcemia. In addition to patients with hypoparathyroidism, this pathophysiological phenomenon occurs in unsuspecting patients, demonstrating the need for all clinicians in contact with pregnant females to be aware of this uncommon - yet perilous - occurrence.

Influence Of 8-week Exercise Intervention On Mental And Physical Health Outcomes In Postpartum Females

Influence Of 8-week Exercise Intervention On Mental And Physical Health Outcomes In Postpartum Females

Mate Discrimination Using Chemical Cues by Male Guppies.

Males often perform mate choice with the aim of maximizing reproductive success. To identify profitable mates, the males of some animals are known to use visual and chemical cues derived from females. In this study, we aimed to examine mate discrimination by male guppies (Poecilia reticulata) using chemical cues received from females under different reproductive statuses, i.e., virgin females, pregnant females, females after copulation with another male, and post-partum females. We conducted a dichotomous choice experiment for each combination of chemical stimuli from females under different reproductive statuses. In experiment 1, in which females were removed from water that was subsequently used as a chemical stimulus, male preferences did not differ significantly in all combinations of chemical stimuli from females under different reproductive statuses. However, in experiment 2, in which females remained within bottles containing the water used as a chemical stimulus, with the exception of one combination of chemical stimuli, significant differences in male preferences were detected for chemical stimuli derived from females under different reproductive statuses. Overall, males generally showed a preference for chemical stimulus received from females after copulation with other males. The findings of this study indicate that male guppies can discriminate the reproductive status of females based solely on chemical cues that may disappear or degenerate within a short period of time, thereby facilitating profitable mate choice.

Prevalence of Diastasis Recti Abdominis in a Gynecological Population: A Cross-Sectional Study

Background: Diastasis recti is the divarication of rectus abdominal muscles due to the splitting of the mid-line collagen structure called the linea alba. It results in poor body biomechanics and alteration in the center of gravity of the body. It occurs mostly in multiparous females and in those who have poorly toned abdominal musculature. Physical activity and maternal care are significant to resolve this condition. Objective: The purpose of the study is to substantiate the prevalence of diastasis recti in a sample of immediate post-partum females attended by the Allied Hospital of Faisalabad. The aim is to create awareness of DRAM in clinical settings and the general population. Study design: This is a cross-sectional study that included 90 samples of females in the immediate postpartum period. Methodology: Specific assessment was done by finger-width method manually and confirmed the presence of DRAM. The umbilical region was the set point from which measurements were taken. Results and Conclusions: The separation was present and mostly affected the multiparous females. The study showed 63.3% prevalence and normal rectus abdominis is 36.7%. It also verified that 42.2% of females suffered from DRAM above the navel out of 63.3% and the rest are below the umbilicus. DRAM was prevalent to be in the majority of post-partum females. It was more present in the supra-umbilical region. Keywords: Pregnancy, rectus abdominis, multiparous, primiparous, physiotherapy.

Translation and validation of the Pelvic Girdle Questionnaire in the Urdu language.

The Pelvic Girdle Questionnaire (PGQ) is designed to determine pain and limited activities in pregnant and postpartum women with pelvic girdle pain (PGP). The purpose of this study was to translate the PGQ into the Urdu language and find out the cross-cultural validity and reliability of the Urdu PGQ among pregnant and postpartum women. A translation and cultural adaptation study was performed following international guidelines. The PGQ (the Urdu version) was drafted and a pilot study was conducted on 16 pregnant and postpartum women. A total of 125 pregnant and postpartum females participated in this study for validity and test-retest reliability. SPSS 25 was used for data analysis. Content validity was analyzed by the content validity index ranging from (0.92 to 1). Convergent validity was determined by correlating the Urdu version of the PGQ with the Oswestry Disability Index (ODI). Pearson rank correlation coefficient between the PGQ and the ODI (p=0.84) showed convergent validity. Internal consistency and test-retest reliability of the Urdu version of the PGQ were calculated by Cronbach's alpha (α=0.98), and intra-class correlation coefficient (ICC=0.98) respectively. The Urdu version of the PGQ showed good content and convergent validity as well as high internal consistency and test-retest reliability.