Introduction. Despite the positive trends in the field of industrial and consumer waste management, issues related to the legal regulation of activities to eliminate objects of accumulated damage to the environment and its relationship with activities to eliminate unauthorized landfills remain unresolved. A separate and important problematic aspect is the assignment of waste to a certain hazard class and their subsequent accounting and neutralization. The study aims to consider the established practice of using sanitary-epidemiological and environmental legislation in the management of industrial and consumer waste, including in assessing their toxicity. Materials and methods. The authors conducted the study using an information and analytical method for analyzing regulatory documentation and scientific publications from the databases Elibrary, Scopus, Web of Science, PubMed, Techexpert, Consultant, etc. They also compared the topical issues of assessing the toxicity of production and consumption waste and identified the specifics of the methodology for calculating the amount of damage as a result of unauthorized waste disposal. Results. It has been established that one of the optimal solutions in the issue of assessing the hazard class of waste may be to bring the criteria for their classification according to the degree of toxicity to uniformity, as well as the development of a single document carried out by institutions regardless of departmental subordination. Studies conducted to determine the amount of damage as a result of unauthorized disposal of production and consumption waste and to establish the hazard class of waste must comply with the requirements of uniformity of measurements and accreditation in the national system, respectively. To correctly calculate the amount of harm, you need to use the value of the mass of waste with the same hazard class. The availability of separate documents in sanitary-epidemiological and environmental legislation can significantly affect the calculation of the amount of harm due to various methods of determining the hazard class of waste, as well as the timeliness of identifying the long-term impact of waste on the environment and public health. Limitations. The study is limited to the analysis of law enforcement practice in the field of waste management, as well as the results of research in domestic and international literature. The analysis will allow researchers to consider non-obvious and controversial issues in the planning of activities. Conclusion. Updating documents on the establishment of the hazard class of waste should be carried out considering law enforcement practice. The absence of duality in compliance with the established requirements in both the field of environmental and sanitary-epidemiological legislation can be a guarantee of the reliability and truthfulness of research. This will allow you to make the right management decisions. Ethics. The study does not require the submission of the conclusion of the biomedical ethics committee.