AbstractIn this study, we offer an extensive examination of the F‐region ionospheric disturbances during the May 2024 superstorm, focusing primarily on the middle‐low latitude regions of East Asia. Our analysis is grounded in a wealth of data sources including Total Electron Content (TEC), ionospheric parameters NmF2 and hmF2, Electron Density Profile (EDP) retrieved from Radio Occultation (RO) data, and ∑[O]/[N2] from the Global Ultraviolet Imager (GUVI), among others, complemented by model simulations. The observed negative ionospheric storm effect, characterized by a significant and long‐lasting reduction in electron density across the entire China, commenced immediately following the sudden storm commencement (SSC) on 10 May and continued through the main and early recovery phase of the storm on 11 May. On 11–12 May, positive ionospheric storm impacts were initially observed in a restricted geographical area from the post‐midnight to sunrise, first manifesting over the eastern regions of China and then shifting to the central regions. Subsequently, a pronounced negative storm effect persisted throughout the later stages of recovery phase. In contrast, the western regions of China experienced a positive storm effect on 12 May followed by a comparatively mild negative storm phase. This persistent extensive zonal gradient in electron density across the East Asian region resembles the scenarios depicted in prior superstorms attributed to the thermospheric circulation patterns. The disparity in the ionospheric response from east to west in this area is probably a common feature during superstorms, potentially resulting from an arch‐shaped structure of elevated ∑[O]/[N2].