Portable Pump Research Articles

An Analytical View on the Use of Flucloxacillin for Outpatient Parenteral Antimicrobial Therapy.

Although the addition of buffers provides improved stability to flucloxacillin (FLU) solutions, unbuffered solutions are often preferred in clinical practice. The first purpose of this study was to investigate whether a 50 mg/mL solution of FLU in normal saline is stable for 24 h at 33 °C so that it can be applied for outpatient parenteral antimicrobial therapy (OPAT) using portable elastomeric infusion pumps (PEIPs). When the PEIPs were stored in an oven at 33 °C and deflated over 24 h, the volume of the collected solution, pH, and FLU concentration were checked every 4 h. Obtaining better results than expected based on the literature data, other storage conditions, such as refrigeration, room temperature (RT), 37 °C, refrigeration followed by 24 h at 33 °C and 37 °C, and different batches/brands, were also tested. This study confirmed the pronounced effect of temperature on the stability of FLU and also showed the relationship between the stability of FLU and the initial pH of the solution. FLU was quite stable at refrigeration and RT conditions, with more than 99% and 95% remaining. After 24 h at 33 °C, more than 92% of FLU was still present in the solution, while this number decreased to less than 85% when the storage temperature reached 37 °C. The remaining percentage was found to be even lower when the solution was stored at 2-8 °C for 6 days, followed by 24 h storage at 33 °C or 37 °C, with losses of 17% and 30%, respectively. The stability of FLU became worse when the initial pH of the solution was lower than 5.9 since the concentration of FLU dropped to less than 90% after 24 h at 33 °C, and a precipitate started to form when the initial pH of the solution was around 5.3. Therefore, FLU in PEIPs could be employed for 24 h if the temperature was ideally not more than 33 °C, while the pH should be not less than 5.9 upon reconstituting the FLU solution.

Axial-flow polymer bridge pump with hydrodynamic bearings.

A portable axial-flow polymer bridge pump with hydrodynamic bearings has been developed for bridge-to-bridge use. The pump is inexpensive to manufacture and disposable. It weighs 185g and was verified to have a lifetime of 3months with silent operation. For partial circulatory assist at a flow rate of 2 L/min, the clinical limit of hemolysis was verified for a rotational speed below 9000rpm, at which a pressure of 100mmHg was generated. In an anti-thrombogenic test, the pump stably operated for 6h without thrombus formation.

Airborne particulate matter and diesel engine exhaust on infrastructure construction sites in the Copenhagen metropolitan area.

Diesel engine exhaust (DEE) is carcinogenic and potentially hazardous for those working in close proximity to diesel-powered machines. This study characterizes workplace exposure to DEE and its associated particulate matter (PM) during outdoor construction activities. We sampled at 4 construction sites in the Copenhagen metropolitan area. We used portable constant-flow pumps and quartz-fiber filters to quantify personal exposure to elemental carbon (EC), and used real-time instruments to collect activity-based information about particle number and size distribution, as well as black carbon (BC) concentration. Full-shift measurements of EC concentration ranged from < 0.3 to 6.4 µg/m3. Geometric mean (GM) EC exposure was highest for ground workers (3.4 µg/m3 EC; geometric standard deviation, GSD = 1.3), followed by drilling rig operators (2.6 µg/m3 EC; GSD = 1.4). Exposure for non-drilling-rig machine operators (1.2 µg/m3 EC; GSD = 2.9) did not differ significantly from background (0.9 µg/m3 EC; GSD = 1.7). The maximum 15-min moving average concentration of BC was 17 µg/m3, and the highest recorded peak concentration was 44 µg/m3. In numbers, the particle size distributions were dominated by ultrafine particles ascribed to DEE and occasional welding activities at the sites. The average total particle number concentrations (PNCs) measured in near-field and far-field positions across all worksites were 10,600 (GSD = 3.0) and 6,000 (GSD = 2.8)/cm3, respectively. Sites with active drilling rigs saw significantly higher average total PNCs at their near-field stations (13,600, 32,000, and 9,700/cm3; GSD = 2.4, 3.4, and 2.4) than sites without (4,700/cm3; GSD = 1.6). Overall, the DEE exposures at these outdoor construction sites were below current occupational exposure limits for EC (10 µg/m3 in Denmark; 50 µg/m3 in the European Union), but extended durations of exposure to the observed DEE levels may still be a health risk.

Impact of a department-sponsored portable breast pump initiative at a single institution

Rationale and objectivesMany barriers to breastfeeding upon return to the workplace are reported by female radiologists, which have implications on maternal/infant health and physician burnout. The Department of Radiology at our institution piloted an initiative to provide a free portable breast pump to address these barriers. Materials and methodsAn anonymous voluntary 32-question survey assessing the impact of the portable pump on postpartum work-life integration was sent to all female radiologists and radiologists-in-training in the department from May 2023 to July 2023. ResultsA total of 59 surveys were completed (65 % response rate). Overall, respondents reported a positive or very positive impact of the pump on transitioning back to work (median 4.5/5 on a 5-point Likert scale), on their decision to continue breastfeeding when returning to work (median 4/5), and duration of breastfeeding (median 4/5). Use of the pump was reported as favorable, with utilization of the pump while simultaneously engaging in clinical work (median 4.5/5) obviating necessity of dedicated lactation rooms, and positive impact on daily productivity (median score of 4/5). Nearly all (94 %, 16/17) users of the portable pump had their lactational needs addressed while returning to work, compared to 54 % (6/13) of those returning from leave prior to the pump initiative (p = 0.003). Compared to those utilizing traditional lactational resources, those who utilized the portable pump were significantly less likely to miss educational opportunities (0 % vs 44 %, p = 0.03), or academic engagements due to lactational practices at work (0 % v 44 %, p = 0.01). ConclusionA department-sponsored portable breast pump initiative proved to be an effective resource to support physician breastfeeding and work-life integration.

Patient Satisfaction Survey on Portable Infusion Pumps for Colorectal Cancer Chemotherapy: Hard-Shelled or Soft-Shelled?

Elastomeric infusion pumps are widely used in colorectal cancer chemotherapy. However, no studies to date have investigated patient preferences regarding different infusion pump types. Twenty patients with unresectable colorectal cancer undergoing chemotherapy were initially treated with a portable hard-shelled continuous infusion pump, followed by a soft-shelled continuous infusion pump. The respondents used a numerical rating scale (0-10) to rate their comfort when using each pump, their ease of carrying it, the pump size and shape, its weight, their ease of reading its memory, and their overall satisfaction with it. They were then asked to determine which pump they would ultimately prefer. In terms of comfort, significantly higher user satisfaction was reported for the soft-shelled pump during the daytime and when going out (P < 0.001, P < 0.001, respectively). For pump portability, size, shape, and weight, the soft-shelled type also outperformed the hard-shelled one (P < 0.001, P=0.0011, P < 0.001, respectively). However, the hard-shelled pump scored significantly better in terms of ease of viewing memory (P < 0.001). Overall satisfaction was significantly higher for the soft-shelled pump than the hard-shelled type (P=0.0095). Finally, 13 patients (65%) indicated that they would prefer a soft-shelled pump for their next treatment, while only one patient (5%) preferred a hard-shelled alternative. A preference for soft-shelled pump was observed, particularly in female patients and those with a body mass index of < 22 kg/m2. The selection of portable elastomeric infusion pumps should consider the preferences of patients with colorectal cancer, as these devices have the potential to enhance their quality of life.

A Comprehensive Approach to Parkinson's Disease: Addressing Its Molecular, Clinical, and Therapeutic Aspects.

Parkinson's disease (PD) is a gradually worsening neurodegenerative disorder affecting the nervous system, marked by a slow progression and varied symptoms. It is the second most common neurodegenerative disease, affecting over six million people in the world. Its multifactorial etiology includes environmental, genomic, and epigenetic factors. Clinical symptoms consist of non-motor and motor symptoms, with motor symptoms being the classic presentation. Therapeutic approaches encompass pharmacological, non-pharmacological, and surgical interventions. Traditional pharmacological treatment consists of administering drugs (MAOIs, DA, and levodopa), while emerging evidence explores the potential of antidiabetic agents for neuroprotection and gene therapy for attenuating parkinsonian symptoms. Non-pharmacological treatments, such as exercise, a calcium-rich diet, and adequate vitamin D supplementation, aim to slow disease progression and prevent complications. For those patients who have medically induced side effects and/or refractory symptoms, surgery is a therapeutic option. Deep brain stimulation is the primary surgical option, associated with motor symptom improvement. Levodopa/carbidopa intestinal gel infusion through percutaneous endoscopic gastrojejunostomy and a portable infusion pump succeeded in reducing "off" time, where non-motor and motor symptoms occur, and increasing "on" time. This article aims to address the general aspects of PD and to provide a comparative comprehensive review of the conventional and the latest therapeutic advancements and emerging treatments for PD. Nevertheless, further studies are required to optimize treatment and provide suitable alternatives.

In-Situ Lithium Analysis In MgLi Alloys Using Laser-Induced Breakdown Spectroscopy with a Compact Chamber.

This study explores the feasibility of in situ Lithium (Li) analysis in Magnesium-Lithium (MgLi) alloys using Laser-Induced Breakdown Spectroscopy (LIBS). It focuses on two Li emission lines: Li I 670.8 nm (resonance) and Li I 610.4 nm (non-resonance). Comparing characteristics at atmospheric and low pressures, self-reversal signatures are observed in both emission lines at atmospheric pressure, complicating the analysis. Challenges in suppressing self-reversal effect using laser energy and detection window adjustments are noted. To address this, a compact chamber (80 mm×50 mm×50 mm) with adjustable pressure (using a portable vacuum pump) is developed. Lowering the pressure significantly reduces self-reversal effect, particularly for the Li I 610.4 nm line. This makes Li I 610.4 nm more suitable for analyzing high Lithium concentrations in MgLi alloys. Using standard samples, such as LA91 (8 % Li) and LA141 (14 % Li), the study successfully obtains Li I 610.4 nm spectra with proportional Li emission intensities. Even with a commercially affordable time-integrated charge-coupled device (CCD) detection system, the results indicate the efficacy of this approach for in situ Li analysis in MgLi alloys.

Outpatient parenteral antibiotic therapy (OPAT) through elastomeric continuous infusion pumps in a real-life observational study: Characteristics, safety, and efficacy analysis

IntroductionThis study aimed to present real-life data on the use, efficacy, and safety of administering antibiotic therapy through portable elastomeric pumps (pEP) in the outpatient setting. MethodsThis retrospective observational cohort study was conducted from January 2020 to May 2023 in a large academic hospital in Rome, Italy. All patients receiving antibiotic therapy via pEP were included up to a follow-up period of 90 days after the end of antibiotic therapy.The primary outcome was the treatment response. Secondary endpoints were adverse events attributable to the drug administered, the vascular catheter, or the infection itself. ResultsOf the 490 patients referred to our outpatient parenteral antibiotic therapy (OPAT) unit, 94 (19.2%) received antibiotic therapy via pEP and were included in the final analysis. The most frequently treated infections were those involving bone and prosthetics, including spondylodiscitis (n=27; 28.8%). Most infections were due to Pseudomonas aeruginosa (n=55; 48.3%). Cefepime (n=32; 34.0%), piperacillin/tazobactam (n=29; 30.9%), ceftolozane/tazobactam (n=7; 7.5%), and oxacillin (n=7; 7.5%) were the most frequently administered antibiotics. The infection cure rate reached 88.3% (n=83). 12 patients (12.8%) reported adverse events, of which half (6.4%) were drug-related and half (6.4%) were line-related. ConclusionsOPAT through portable elastomeric infusion pumps proved to be safe and effective. It also contributed to the reduction of healthcare costs, fully respecting the principles of personalized medicine. This strategy has emerged as a promising tool for antibiotic stewardship and infection control.

Adherence to caregiver-administered intravenous immunosuppressant medications in pediatric hematopoietic stem cell transplant.

The purpose of this study was to describe taking, timing, and dosing adherence to home caregiver-administered intravenous (IV) immunosuppressants in a sample of pediatric hematopoietic stem cell transplant (HCT) recipients. Sixteen children who had undergone HCT, ages 3 months to 15 years, and their caregivers participated. All caregivers were biological mothers. Caregivers completed a demographic questionnaire as part of a larger study and brought in portable infusion pumps to download the pump data at the time of their child's post-HCT clinic visit. Pump data were then examined for dose taking, timing, and amount for 30 days following discharge. Despite the importance of the precise timing of IV immunosuppressants, adherence taking, dosing, and timing varied widely in this sample. The mean percentage of doses administered was 98.72%, and 81.3% of children received all doses of immunosuppressant. However, only 62% of doses were given on time and the mean difference between the prescribed and actual administration time was 67.03 minutes. Although taking adherence was high, the timing and dosing adherence to IV immunosuppressants in the home was poor. Additional support to promote adherence should be provided including assisting caregivers to identify and use adherence strategies specific to their child's IV immunosuppressant regimen in the home.

Abstract 3027: Home-based, High-pressure Intermittent Limb Compression Following Lower Extremity Revascularization In Patients With Severe Peripheral Artery Disease: A Pilot Trial

Objective: Many patients who undergo lower extremity revascularization (LER) for peripheral artery disease (PAD) continue to experience mobility impairment despite adequate revascularization. High-pressure intermittent limb compression (HPILC) has been shown to augment leg blood flow and improve walking endurance in symptomatic PAD patients. This pilot trial aimed to examine the feasibility of home-based HPILC for 2 hours daily over 3 consecutive months in patients who underwent LER for PAD. The primary outcome was the change in 6-minute walk distance from baseline to 3-month follow-up. Methods: Three months following LER, 9 participants were randomly assigned to either HPILC (n=5) or a sham (n=4) group. Participants were provided with a portable pneumatic air pump and inflatable cuffs that were wrapped around the feet, ankles, and calves (ArtAssist, ACI Medical). The inflation pressures were 120 mmHg and 30 mmHg in the HPILC and sham devices, respectively. A built-in timer, inaccessible to participants, provided one estimate of treatment compliance. Outcomes were assessed before and after the completion of the 3-month interventions. Results: Among the 9 randomized participants, one individual required reintervention and was withdrawn from the study. Adherence to treatment was 74% for HPILC and 92% for sham. As shown in Figure 1, the change in 6-minute walk distance from baseline tended to be higher in the HPILC group compared to the sham-treated group (HPILC: 35.2±38.7 m vs. Sham: -14.7±25 m, p=0.07). There were no group differences in the secondary outcomes, including the changes in the ankle-brachial index, the toe-brachial index, and the Vascular Quality of Life questionnaire scores. Conclusions: Home-based HPILC following LER for PAD is feasible, well-tolerated, and appears to improve walking performance. These preliminary findings indicate that HPILC may be a useful adjunct therapy to enhance lower extremity functioning in patients recovering from LER.

Validation of EPG/SAG Rev. 4 of the Kuosheng Nuclear Power Plant Using the MAAP5 Code

The Boiling Water Reactor Owner’s Group released Emergency Procedure Guidelines and Severe Accident Guidelines Revision 4 (EPG/SAG Rev. 4) in 2018. The major improvement to EPG/SAG Rev. 4 was Contingency 1 (Alternate Level/ Pressure Control). Contingency 1 coordinates the reactor pressure vessel (RPV) water level and RPV pressure control action to prolong the availability of steam-driven injections and optimize the transfer to motor-driven systems. In this study, the effectiveness of the EPG/SAG Rev. 4 Contingency 1 strategy was compared with those of EPG/SAG Revision 2 Contingency 1 and Specific Major Incident Guidelines (SMI) using the Modular Accident Analysis Program, Version 5 (MAAP5). SMI was developed by the Taiwan Power Company to mitigate a Fukushima-like accident. The surrogate plant that analyzed is the Kuosheng Nuclear Power Plant (NPP). The Kuosheng NPP is BWR-6 Mark-III containment. MAAP5 is an integral severe accident analysis program that simulates the responses of a light water reactor power plant during a severe accident. This program has been used extensively for probabilistic risk assessments and for verification and validation of mitigation actions specified in severe accident management guidelines. The simulation scenarios were extended loss of alternative-current power and loss of ultimate heat sink. The low-capacity, motor-driven portable pump was the only available system for RPV injection in the first hour of the accident. In this time period, the RPV water level and pressure were controlled by reactor core isolation cooling and safety relief valves. After this study, the strategy of EPG/SAG Rev. 4 Contingency 1 was successfully validated, and the effectiveness of minimum pre-depressurization RPV water level and the low-capacity, motor-driven portable pump were also demonstrated in this study.

Analysis of the Effect of Ambulatory Chemotherapy (Portable Infusion Pump Use) Video Education on Knowledge, Self-efficacy, and Anxiety of Colorectal Cancer Patients

Objective: To analyze the effect of video education on ambulatory chemotherapy with a portable infusion pump on the knowledge, self-efficacy, and anxiety of colorectal cancer patients. Methods: This study employs a quasi- experimental study as a nonequivalent control group and a non-synchronized design. The 48 participants selected in this study were colorectal cancer patients who received chemotherapy with a portable infusion pump through an ambulatory care unit. Patient education was divided into printed materials and videos, and the patient’s knowledge, self-efficacy, and anxiety were measured. Data were analyzed using independent t-test, paired t-test, and Wilcoxon’s signed rank test. Results: In the video education group, the patient’s knowledge (Z = -4.09, P &lt; 0.001) and self-efficacy (Z = -2.72, P = 0.012) significantly increased after education, and anxiety significantly decreased (Z = 2.24, P = 0.035). However, there was no difference in knowledge (t = 0.09, P = 0.931), self-efficacy (t = 1.22, P = 0.229), and anxiety (t = -1.16, P = 0.250) between the two groups after education. Conclusion: To improve the quality of life of cancer patients, it is necessary to promote self-efficacy and reduce anxiety. The results of this study suggested that more diverse educational methods should be attempted to improve knowledge and self-efficacy and reduce anxiety in colorectal cancer patients.

A Peristaltic Pump to Improve Bladder Emptying and Irrigation in Patients Who Use Clean Intermittent Catheterization

Background: Neurogenic bladder patients who intermittently catheterize may have systems that drain slowly and incompletely. These limitations can lead to urinary tract infections and bladder stone formation and be time consuming. We hypothesize that a catheter accessory device could improve drainage, reduce residual bladder volume, and save time. Methods:&amp;nbsp;A yearlong collaboration between an undergraduate biomedical engineering student design team and client mentors from the pediatric urology department led to an evaluation of solutions to enhance emptying of bladders that require intermittent catheterization. Students performed market analysis, identified design requirements, generated design concepts, conducted usability testing, and constructed alpha and beta prototypes verified through benchtop experimentation during the yearlong project. Prototypes were verified using a phantom bladder model built from a compliant stress ball with an attached catheter and placed under an external pressure of 5 cm H 2 O. Tests were conducted to measure the diff erence between passive drainage and device-assisted drainage at various bladder volumes and catheter sizes. Eight student peers compared passive emptying, irrigating, and aspirating a phantom bladder model using the prototype or syringe to assess the usability of the device. Results:&amp;nbsp;We developed a pump that interfaces with commercially available catheters. The&amp;nbsp;pump housing was designed and 3D printed. Fluid can be moved bi-directionally with&amp;nbsp;a battery-powered peristaltic pump and microcontroller. The pump has a built-in current&amp;nbsp;sensing threshold with an automatic shutoff safety mechanism. Testing results showed&amp;nbsp;that for all bladder volumes and catheter sizes, the pump emptied more completely and&amp;nbsp;drained between 1.6 and 6.3 times faster when compared to passive drainage. Usability&amp;nbsp;feedback showed that the pump required less time to irrigate the bladder and was preferred&amp;nbsp;when compared to the manual syringe technique. Conclusions: This portable catheter pump improves phantom bladder emptying by increasing flow rate, decreasing residual volume, and making irrigation easier. Future design improvements will work to implement safety mechanisms and miniaturize the pump. This project demonstrates the feasibility of a catheter accessory device to improve patient quality of life and the ability for understudied clinical problems to be addressed through collaborations between capstone engineering design teams and physicians.

Portable high-pressure pump system for HPLC combining pressurized gas and on-chip pressure regulation

High-pressure pumps for microfluidic systems typically require high power and have large sizes, which hinder portability of otherwise miniaturized HPLC systems. To solve this, a battery-powered, pneumatic system for pressure-driven chromatography is presented. The system utilizes the stored energy in pressurized gas without consuming any of the gas. As the chromatography liquid flows, the gas in the pressure container expands and its pressure reduces. To compensate for this, a solution is presented with an on-chip microfluidic pressure regulator. The chip contains a microfluidic restrictor where fluid is heated by Joule heating to decrease viscosity, and thus reduce the pressure drop over the restrictor. An 18 V battery driven system with 50 ml N2 at 51 bar could provide a water flow rate of 55μl/min at 32 bar for 67 min with a mean power consumption of 0.2 W. With the regulating microfluidic chip, the pressure stability was 2 mbar, i.e., on pair with high-quality high-pressure syringe pumps. The required gas volume, and hence the total size, is scalable with the desired liquid volume, which makes it suitable for miniaturized systems.

Electrostatic-driven soft air pump with segmented electrodes

Pneumatic soft robots have become a popular research area for future robots because of their lightweight, high efficiency, non-pollution, and high reliability. However, the pneumatic pump, which is the ‘heart’ of these robots, is large in size, heavy in weight, noisy in operation, and must be separated from the robot body, which seriously affects the portability and autonomy of the robot. Portable soft pumps fabricated using smart materials provide a viable solution to the above challenges. We present a segmented electrode pump (SEP) driven by electrostatic forces, which combines the advantages of an electro-pneumatic pump (EPP) and an enhanced electrode structure. Compared with the EPP, the developed SEP showed improved characteristics in terms of higher specific flow rate output (1.67 ml s∙g−1), higher specific pressure output (0.483 kPa g−1) and lower power consumption (24 mW). The proposed SEP is expected to provide new solutions to the challenges of embedding air sources and facilitating air supply flexibility, and opens up new opportunities for fully flexible robots.

Cavitation performance analysis and optimal design of the portable electric-driven axial flow pump

Based on the ISIGHT optimization platform, the impeller parameterization modeling and simulation process of the portable axial flow pump is carried out through CFturbo, ICEM and CFX software, and the impeller is optimized with the help of multi-island genetic algorithm to target the two optimization objectives of efficiency and head. The optimization results show that the hydraulic efficiency increased by 6.3% under design conditions. At the same time, compared with the original solution, the optimized cavitation performance is significantly improved. Additionally, overall entropy production is significantly reduced. Field test results show that the head deviation is 1.42% and the efficiency deviation is 4.52% under design conditions, proving that the optimization results are reliable.

Comparison of two types of extension tubes for people with Parkinson’s disease in advanced treatment with levodopa–entacapone–carbidopa intestinal gel infusions: a prospective, crossover quality study

BackgroundWithin Parkinson’s disease (PD) management, a pivotal juncture often arises when individuals with PD (PwP) necessitate advanced therapies to stabilise symptom fluctuations and reduce off-periods, which are intrinsic to living...

Fully 3D-printed, nonelectric, spring-powered syringe pump for operating microfluidic devices

Microfluidic devices require a precise and steady flow for fluid control. The high demand for microfluidics in point-of-care testing (POCT) necessitates a portable, low-cost, and electricity-free pumping method for operating microfluidic platforms in low-resource settings. This study presents a fully 3D-printed and portable syringe pump operated by torque from a flat spiral spring. The syringe pump can be operated by manually winding up the spring, and various flow rates can be obtained using different syringe sizes and selecting appropriate gear combinations. It generated a steady flow rate ranging from 1.4 µL/min to 12.0 µL/min with high repeatability. The pump is suitable for the on-site use of microfluidic platforms because it does not require electricity and does not occupy a large space. The 3D printed pump proposed in this study is named precise, rapid-prototyped, nonelectric, torque-driven (PRNTD) pump. The versatility and utility of the pump are demonstrated by generating a linear concentration gradient using a microfluidic gradient generator and microdroplets using a T-channel microfluidic chip. The PRNTD pump can facilitate the on-site application of microfluidic platforms in resource-limited settings and contribute to the widespread use of microfluidic technologies.

Exploring the administration of intravenous antibiotics and fluids via portable intravenous pump versus intravenous pump and pole to improve mobility in patients diagnosed with cancer (The ACTIVE Trial): A randomized controlled trial protocol

Purpose: Haemato-oncology patients who require treatment for infections in the hospital receive intravenous antibiotics (IVABs) and intravenous therapy (IVT) via an infusion pump attached to a pole on wheels. This IV pole can hinder a patient’s mobility and ability to perform activities of daily living. A computerized ambulatory delivery device (CADD), often used in the outpatient or home setting, is a portable infusion pump that delivers IVABs and IVT without the need of a wheel-based pole. This study will investigate the use of portable CADDs in the inpatient setting to determine if they improve patients’ mobility when compared with using the IV pole. Methods: A randomized controlled trial of patients requiring IVABs or IVT, of two haemato-oncology wards in a large, quaternary hospital, will recruit 110 adults randomized on a 1:1 basis into either a CADD arm or an IV pole arm. The primary outcome is mobility as assessed by number of steps per day (recorded via accelerometer). Secondary outcomes include sleep disturbance, quality of life, and hospital-acquired complications. All randomized patients will be analyzed by intention to treat.

Utilization of IP LM393 Sensor Module as an Automation System for a Portable Gallon Pump

Research has been conducted on developing an automatic gallon pump based on the IP LM393 sensor. This research aims to provide alternative solutions to avoid direct contact as the cause of COVID-19 transmission. The research method used includes the stages of designing, manufacturing, and testing the automatic gallon pump based on the IP LM393 sensor. The results showed that installing IP LM393 in a portable gallon pump can help people avoid direct contact when pouring water. This research proves that some materials can be sensor barriers at specific distances with an effective light intensity range of 19-23 lux.