Poor Conditions Research Articles

The hydrological response of melting ephemeral snowpacks compared to winter rainfall events in a mid-mountainous Pyrenean catchment

AbstractThe hydrological role of ephemeral snowpacks and their differences in stormflow and sediment transport characteristics compared to events triggered by winter rainfall conditions have received limited attention. This study aims to analyze the hydrological and sediment transport responses to rain-on-snow (ROS), melt, mixed, and rainfall events in the Araguás Catchment, situated in a mid-mountain site of the Central Spanish Pyrenees, with a climate strongly influenced by Mediterranean conditions. This catchment represents the transition from a winter ephemeral snow environment to a fully rainfall-dominated site. Results indicate that snowmelt has a modest yet measurable impact on the annual water balance, averaging 10% and rising to 30% during winter (December to February). ROS and melt events consistently exhibited higher mean and maximum discharge and elevated stormflow coefficients compared to mixed and rainfall events. The lowest water infiltration into the soil was observed during melt events, attributed to the potential for frequent freezing soils, specific poor edaphic conditions, and the rapid snowmelt in the area. Consequently, melting events displayed the shortest flood hydrographs among the four analyzed events. The study also underscores precipitation’s almost negligible erodibility capacity in the solid phase and emphasizes the protective role of snow cover in preventing soil erosion. It is important to note that the presented results are significantly influenced by the physiographic, lithological, and edaphic characteristics of the Araguás Catchment. This highlights the importance of conducting more detailed analyses of ephemeral snowpacks in experimental sites under a broader range of environmental conditions for a comprehensive understanding.

Examining the intersection of carceral space and well‐being: Correctional officers' perspectives on old and new prison design

AbstractIn the current study, we explored the prison design and infrastructural changes that Canadian correctional officers consider to be essential in the construction of a new provincial correctional institution intended to replace Her Majesty's Penitentiary (HMP) in the Canadian province of Newfoundland and Labrador. Analyzing 28 semi‐structured interviews conducted with correctional officers employed at HMP, we found the poor working conditions within HMP are, at least in part, related to the physical design of the prison, including inadequate lighting, poor air quality and temperature, high sound levels, and other spatial limitations. Building on the prison design literature, findings suggest that while prison design requires attention to physical security at the forefront, there are ways to improve the space, recognizing how an uncomfortable workplace and living conditions also pose a potential threat to the well‐being and safety of correctional officers and people who are incarcerated.

Regulatory Mechanism of Xiaozheng Tongluo Method on Hepatic Lipid Metabolism in ApoE-/- Mice: Insights from the Sterol Regulatory Element-binding Protein-2/3-hydroxy-3-methylglutaryl Coenzyme A Reductase/Low-density Lipoprotein Receptor Signaling Pathway

Abstract Objective: The objective of the study was to explore the regulatory mechanism of the Xiaozheng Tongluo method on lipid metabolism in liver tissue based on the sterol regulatory element-binding protein-2/(SREBP2)/3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR)/low-density lipoprotein receptor (LDLR) signaling pathway. Materials and Methods: C57BL/6 mice were selected as the blank group. The apolipoprotein E-deficient (ApoE-/-) mice were randomly divided into the model group, traditional Chinese medicine (TCM) group, and control group. The general condition of the mice was determined by the mouse’s state and liver weight. Liver hematoxylin and eosin staining and Oil Red O staining were used to observe the pathological changes and lipid droplet deposition of the liver. The protein expression levels of SREBP2, HMGCR, and LDLR were detected by Western blotting and polymerase chain reaction. Results: (1) The rats in the model group were in poor condition, and their liver weight increased significantly. Compared with the model group, the condition of the TCM group and the control group improved to varying degrees, and their liver weight decreased significantly. (2) Compared with the normal group, the hepatocytes in the model group were arranged in a disorderly manner, and the red-stained lipids of stem cells increased significantly. Compared with the model group, the degree of liver lesions in the control group and TCM group was reduced, and the red-stained lipid of hepatocytes was significantly reduced. (3) Compared with the blank group, the expression of SREBP2 and HMGCR protein in the model group increased significantly, and the expression of LDLR protein decreased significantly (P < 0.05). Compared with the model group, the expression of SREBP2 and HMGCR protein in the TCM group decreased significantly, and the expression of LDLR protein increased significantly (P < 0.05). Conclusions: The method detailed in this paper can increase the expression of SREBP2 and HMGCR protein and decrease the expression of LDLR protein, thus regulating liver cholesterol metabolism and delaying the progression of atherosclerosis.

The impact of humanitarian aid on financial toxicity among cancer patients in Northwest Syria

IntroductionThe ongoing crisis in Syria has divided the country, leading to significant deterioration of the healthcare infrastructure and leaving millions of people struggling with poor socioeconomic conditions. Consequently, the affordability of healthcare services for the population has been compromised. Cancer patients in Northwest Syria have faced difficulties in accessing healthcare services, which increased their financial distress despite the existence of humanitarian health and aid programs. This study aimed to provide insights into how humanitarian assistance can alleviate the financial burdens associated with cancer treatment in conflict-affected regions.Materials and methodsThis research employed a quantitative, quasi-experimental design with a pre-test-post-test approach, focusing on evaluating the financial toxicity among cancer patients in Northwest Syria before and after receiving humanitarian aid. The study used purposeful sampling to select participants and included comprehensive demographic data collection. The primary tool for measuring financial toxicity was the Comprehensive Score for Financial Toxicity (FACIT-COST) tool, administered in Arabic. Data analysis was conducted using SPSS v25, employing various statistical tests to explore relationships and impacts.ResultsA total of 99 cancer patients were recruited in the first round of data collection, out of whom 28 patients affirmed consistent receipt of humanitarian aid throughout the follow-up period. The results of the study revealed that humanitarian aid has no significant relationship with reducing the financial toxicity experienced by cancer patients in Northwest Syria. Despite the aid efforts, many patients continued to face significant financial distress.ConclusionThe research findings indicate that current humanitarian assistance models might not sufficiently address the complex financial challenges faced by cancer patients in conflict zones. The research emphasizes the need for a more comprehensive and integrated approach in humanitarian aid programs. The study highlights the importance of addressing the economic burdens associated with cancer care in conflict settings and calls for a re-evaluation of aid delivery models to better serve the needs of chronic disease patients. The findings suggest a need for multi-sectoral collaboration and a systemic approach to improve the overall effectiveness of humanitarian assistance in such contexts.

Investigating and Improving Pedestrian Safety in an Urban Environment of a Low- or Middle-Income Country: A Case Study of Yaoundé, Cameroon

In Yaoundé, Cameroon, where walking dominates transport modes, pedestrian safety remains an issue as pedestrians account for a fair share of road traffic casualties, partly due to the lack of walking policies and pedestrian facilities safety data, hindering targeted intervention. This study used a pedestrian safety index (PSI) and the Global Walkability Index (GWI) to investigate 12 road segments frequented by diverse pedestrian groups. Indexes were graded from E—lowest to A—highest and analyzed using description and rank correlation. Main safety issues included lack of adequate and accessible sidewalks, bollards, pedestrian crossings, signage, shade, and street lighting. Only one segment (R7) achieved grade C, while the remainder scored D or E, indicating poor pedestrian safety conditions and an unpleasant walking experience. The correlation coefficient (0.69) between the PSI and GWI at a 99% significance level validated the safety assessment, providing confidence in the results. A seven-year (2024–2030) safety strategy is proposed to improve all roads to grade B. This strategy contains several interventions, including engineering improvement, which have been proven effective. This study offers evidence for city officials to improve pedestrian safety and informs walking policies and the implementation of upcoming projects. Future research should quantify the recommendations’ benefits and validate indexes with crash or conflict data.

Predictability and transparency of working conditions for food delivery platform workers across selected EU countries

AbstractWhile prior research has demonstrated the poor and unpredictable working conditions and ambiguous working arrangements characteristic of platform‐based food delivery, we lack research on the question of how well these workers are informed about essential aspects of their work, including protection of their rights, working time and schedules, and earnings. Comprehensive and transparent information on working conditions at an early stage is indispensable if workers are to be able to make informed decisions on taking up work and, where relevant, investing in equipment and exercising rights linked to a specific job. Drawing on the multi‐dimensional job quality literature, this article focuses on digital labour platforms in the food delivery sector across four countries: Denmark, Germany, the Netherlands and Spain. We exploit firm‐level variations, including with regard to the types of work arrangements used and the application—or not—of collective agreements. We draw on information provided to riders during the application process prior to the start of employment, including via websites and FAQs, as well as scrutiny of contracts, service agreements and collective bargaining agreements, where relevant. This information is complemented with interviews with trade union representatives. Our findings point to the relationship between a firm's choice of employment status and form of contract, on one hand, and the predictability and transparency of information provided to workers, on the other. Differences and similarities in such information seem to be more strongly bound to firm‐level decisions than to the welfare and industrial relations regimes in which the platform companies operate.

Aortic, mitral and tricuspid valvular dysplasia in a 7‐month‐old colt

SummaryA 7‐month‐old Warmblood cross colt was presented for the assessment of a laceration of the right hind pastern of 4‐days duration. At presentation, the colt was in poor body condition and had a rough, dull coat. Cardiac auscultation revealed a grade 5/6 pansystolic murmur on the left side and grade 4/6 continuous murmur on the left and right sides and a regular cardiac rhythm. Electrocardiographic examination confirmed sinus tachycardia. Echocardiographic examination showed malformation of the aortic and mitral valves, with associated regurgitation and evidence of left atrial and ventricular volume overload. Dysplasia of the mitral, tricuspid and aortic valves was confirmed by post‐mortem examination. Valvular dysplasia is a rare cause of cardiac failure in horses.

Morphological and molecular characterization of Eimeria haematopusi n. sp. (Apicomplexa: Eimeriidae) in an Australian Pied Oystercatcher (Haematopus longirostris) (Aves: Charadriiformes)

A novel Eimeria Schneider, 1875 species is described from an Australian pied oystercatcher Haematopus longirostris Vieillot, in Western Australia. The pied oystercatcher was admitted to the Kanyana Wildlife Rehabilitation Centre (KWRC), Perth, Western Australia in a poor body condition, abrasion to its right hock and signs of partial delamination to its lower beak. Investigation into potential medical causes resulted in a faecal sample being collected and screened for gastrointestinal parasites. Unsporulated coccidian oocysts were initially observed in the faeces and identified as Eimeria upon sporulation. The sporulated oocysts (n = 20) are ellipsoidal, 20–21 × 12–13 μm in shape and have thick bi-layered walls which are c.2/3 of the total thickness. Micropyle is present, robust and protruding, and occasionally has a rounded polar body attached to the micropyle. Within the oocyst, a residuum, in addition, two to five polar granules are present. There are four ellipsoidal sporocysts 9–11 × 5–6 μm with flattened to half-moon shaped Stieda bodies. Sub-Stieda body and para-Stieda body are absent. The sporocysts contain sporocyst residuums composed of a few spherules scattered among the sporozoites. Within the sporozoites, anterior and posterior refractile bodies are present, but the nucleus is indiscernible. To further characterise the novel Eimeria species from H. longirostris, molecular analysis was conducted at the 18S ribosomal RNA locus, using PCR amplification and cloning. Two cloned sequences from the novel Eimeria were compared with those from other Eimeria spp. with the highest genetic similarity of 97.6% and 97.2% from Clone 1 and 2, respectively with Eimeria reichenowi (AB544308) from a hooded crane (Grus monacha Temminck) in Japan. Both sequences grouped in a clade with the Eimeria spp. isolated from wetland birds, which include Eimeria paludosa (KJ767187) from a dusky moorhen (Gallinula tenebrosa Gould) in Western Australia, Eimeria reichenowi (AB544308) and Eimeria gruis (AB544336) both from hooded cranes. Based on the morphological and molecular data, this Eimeria sp. is a new species of coccidian parasite and is named Eimeria haematopusin. sp. after its host H. longirostris.

How old is too old to fight in boxing?

Professional boxing is a popular combat sport worldwide. It is a physically demanding sport, and professional boxers are usually in their mid to late 20’s. At around 35-years of age most boxers begin to show signs of physical decline. Boxers hence begin to retire from professional boxing around 35-years of age. Recently older combatants are entering the ring and cage to ply their trade. These are either former professional combatant who is choosing to come out of retirement or celebrities who are getting pitted against each other in exhibition boxing matches (popularly referred to as celebrity boxing). Many of these “combatants” are on the wrong side of 40, have little to no formal training in combat sports and poor physical conditioning. Boxing and MMA are referred to as combat sports. Neurological, orthopedic, and ophthalmological injuries are common. While some are life threatening others has the potential to cause lifelong disability. Boxers sometimes die in the ring due to acute traumatic subdural hematoma (SDH). Concern is hence raised for the health and wellbeing of these older athletes. Should an athlete above the age of 40 compete in professional boxing? How old is too old to fight in boxing?

Mapping Opium Poppy Cultivation: Socioeconomic Insights from Satellite Imagery

Over 30 million people globally consume illicit opiates. In recent decades, Afghanistan has accounted for 70–90% of the world’s illicit supply of opium. This production provides livelihoods to millions of Afghans, while also funneling hundreds of millions of dollars to insurgent groups every year, exacerbating corruption and insecurity, and impeding development. Remote sensing and field surveys are currently used in official estimates of total poppy cultivation area. These aggregate estimates are not suited to study the local socioeconomic conditions surrounding cultivation. Few avenues exist to generate comprehensive, fine-grained data under poor security conditions, without the use of costly surveys or data collection efforts. Here, we develop and test a new unsupervised approach to mapping cultivation using only freely available satellite imagery. For districts accounting for over 90% of total cultivation, our aggregate estimates track official statistics closely (correlation coefficient of 0.76 to 0.81). We combine these predictions with other grid-level data sources, finding that areas with poppy cultivation have poorer outcomes such as infant mortality and education, compared to areas with exclusively other agriculture. Surprisingly, poppy-growing areas have better healthcare accessibility. We discuss these findings, the limitations of mapping opium poppy cultivation, and associated ethical concerns.

Ethnicity, culture and human development of Bangladesh’s tea workers

ABSTRACT This study sets out to investigate the human development situation of ethnic tea workers in Bangladesh against the underpinnings of human development theories by employing a qualitative research approach. We collected data for this study from people of diverse ethnic backgrounds and identities through in-depth interviews, focus group discussions, and direct observation. The study finds that human development of ethnic tea workers is extremely constrained by the lack of their freedom and adequate income, which is systematically created by the tea planters to serve their business interests. Tea workers’ social isolation from the mainstream Bangladeshi society, coupled with their traditional social life and poor socioeconomic conditions, also manufactured by the regulatory systems, remains the significant marker for the deterrent of their human development. Different traditional beliefs, rituals and practices of these ethic communities are also spotted as contributing factors for their poor human development situation, forcing them to sustain the legacy of working-class status of their predecessors and wind up in the tea plantations for generations.

Analysis of extreme precipitation variation characteristics in mountain grasslands of arid and semi-arid regions in China

Introduction: With global warming, the disaster losses caused by extreme precipitation events are increasing. The poor natural conditions and climate change make the arid and semi-arid mountainous grassland area a sensitive region of climate change. The study on the spatio-temporal variation characteristics of extreme precipitation events in this region is helpful to improve the ability of climate prediction and disaster prevention and reduction in grassland.Methods: Based on the daily precipitation data of four meteorological monitoring stations in the Yinshanbeilu from 1970 to 2020, the trend analysis, M-K test and wavelet analysis were used to select seven typical extreme precipitation indicators to analyze the temporal and spatial characteristics of extreme precipitation.Results and Discussion: The results showed that the precipitation in the Yinshanbeilu increased in the past 51a, and the number of heavy rain days increased significantly. The significance test of CDD and CWD showed that the number of continuous dry days and continuous wet days decreased abruptly. The spatial analysis showed that the high value areas of R95p, R95d and PRCRTOT were all located in Siziwang Banner, and it could be concluded that the extreme precipitation risk was the highest in Siziwang Banner, while the low value areas of SDII, Rx1day, R95p and PRCRTOT were all located in Sonid Right Banner, which could be inferred that the Sonid Right Banner was relatively dry. The first main cycle of the seven indexes of extreme precipitation almost runs through the whole time series, and the starting point of the minimum main cycle changes inconsistent. In addition to the number of consecutive dry days, the other indices have a good correlation with annual precipitation, flood season and monthly precipitation from June to September, and July is the peak period of extreme precipitation events.

Long-term survival after conversion surgery for an esophageal neuroendocrine carcinoma: a case report

BackgroundEsophageal neuroendocrine carcinomas (NECs) are extremely rare. Published information on their clinical features, pathological findings, and prognosis is lacking. The optimal treatment for esophageal NECs has not yet been determined because they appear extremely malignant histologically and have a poor prognosis. We here report on a patient with an esophageal NEC who was successfully treated with multidisciplinary therapies.Case presentationThe patient, a 47-year-old man, was admitted to our hospital with dysphagia and weight loss and an ECOG performance status of 3–4. Upper endoscopy showed a large circumferential neoplasm at the esophagogastric junction. Computed tomography showed lymph node metastases around the left gastric artery. Echocardiography raised a suspicion of invasion of the left atrium. Histopathological examination of biopsy tissue revealed diffuse proliferation of small atypical cells resembling naked nuclei with extensive necrosis and degeneration. The cells showed positive staining for CD56, chromogranin A, and synaptophysin on immunohistochemical analysis. Ki67 was positive in over 90% of cells. He was diagnosed with an esophageal NEC that had infiltrated the left atrium; his cancer was therefore inoperable. Because of his poor overall condition, palliative radiotherapy (30 Gy in 15 fractions) was administered, accompanied by nutritional management. This was followed by four courses of chemotherapy with carboplatin plus etoposide, after which the primary tumor and locoregional lymph node metastases were found to have shrunk. Thoracoscopic- and laparoscopic-assisted McKeown esophagectomy were performed. The postoperative pathological diagnosis was NEC pT3pN0M0 Stage II. The patient had a good postoperative course and received two courses of postoperative adjuvant chemotherapy (carboplatin plus etoposide). Currently, 3 years after commencing treatment, there is no evidence of recurrence.ConclusionsAs mentioned above, there is no established treatment regime for esophageal NEC, and the benefits of conversion surgery are unknown. Our patient achieved long-term recurrence-free survival after radiation therapy, chemotherapy, and surgery for an esophageal NEC with left atrial invasion and multiple lymph node metastases. Conversion surgery for esophageal NECs that respond to chemotherapy may contribute to long-term survival.

Diminishing mangrove forest structures in Davao City, Philippines

The decline of mangrove coverage across the Philippines to 50% of its original coverage in present years has, led to significant reductions of ecological functions to fisheries and benefits to man. The mangrove forest in Davao City was assessed for its taxonomic list, Importance Value Index, abundance and distribution of mangrove regenerations, forest structure, and species diversity status. The study was conducted in Barangay Bunawan, Lasang, Panacan, Matina Aplaya, 76-A, and Bago Aplaya. All data were gathered by establishing sampling plots (10m x 10m) using the modified transect-plot method. Overall, a total of 34 mangrove species were listed, of which 21 were identified as true mangroves and 13 as mangrove associates. The 21 mangrove species were very low in species richness (54%). Importance Value Index showed that Avicennia marina, Rhizophora apiculata, and Sonneratia alba, respectively, as dominant mangrove species. The mangrove regenerations were in poor condition (<0.50) while relative abundances of growth stages consisted of mature stands at 46.04%, saplings with 27.78%, and seedlings with 26.18%. General diversity indices obtained a low value on the Shannon-Wiener diversity index (H'=1.42) and an average value on the species evenness index (E=0.61), all indicating stressful and unstable mangrove forests. Thus, the mangrove forest ecosystem has imbalances and eventually, only certain species would survive.

Bearing Characteristics with Effect of Bond–Slip Behavior in Massive Ring-Type Reinforced Concrete Structures

The bond–slip behavior of the steel–concrete interface is critical in reinforced concrete (RC) structures since the bond action is the mechanism that ensures the two materials work in co-operation. However, there is little research considering the bond–slip behavior in massive ring-type reinforced concrete (MRRC) structure bearing analyses due to the complexity of modeling the interfacial behavior. Hence, the influence of the bond–slip behavior on the bearing characteristics of MRRC structures remains unclear. Steel-lined reinforced concrete penstock is such an MRRC structure, composed of steel liner and reinforced concrete and commonly used in diversion pipelines. This paper aims to explore the bearing characteristics considering the bond–slip behavior in the composite penstock by using a promising numerical method, the cohesive zone model. Three interface models were proposed to represent the different interaction conditions at the steel–concrete interface. Moreover, a sensitivity analysis was performed to study the impact of the bond strength on the bond performance and structural behavior. The simulation results showed that the prediction results (steel stress and crack process) considering the bond–slip behavior were in good agreement with the experimental results. The steel stresses near the cracks were smaller and more uniform after considering the bond–slip behavior, since the stresses were no longer concentrated on the crack but distributed in an area near the crack. However, the steel stress differences in these models were within 10%, which means that the bond performance had a limited effect on the structural safety design. The crack widths were greatly influenced by the bond conditions, and the maximum crack width (0.461 mm) in poor conditions was beyond the limiting value (0.3 mm). Consequently, bond–slip behavior must be paid more attention in durability design.

Research on fire detection method of complex space based on multi-sensor data fusion

Efficient and reliable fire detection methods are essential for addressing complex spatial characteristics of older residential communities, which often face poor fire safety conditions, various fire types, and challenges in rescue operations. In response to the problem of lacking comprehensive analysis of multidimensional data in traditional fire detection, which often leads to false alarms and missed alarms, this paper proposes a fire detection method based on multi-sensor data fusion. Various sensors are employed, including smoke sensors, temperature sensors, CO sensors, and flame sensors. These sensors collect multidimensional data, which are fused using improved adaptive filters and fuzzy Bayesian logical reasoning algorithms to establish a fire detection model based on multi-sensor data fusion. To additionally, false alarms and missed detections caused by sensor damage are further solved by exploring hidden spaces. Experimental results demonstrate that the proposed fire detection system based on multi-sensor data fusion effectively analyses fire occurrence and progression in older residential communities, and performs stability, accuracy and real-time property.

Best management practices for integrating refugee employees

AbstractThe number of international refugees in developed countries continues to increase due to various factors, including war, poverty, poor economic conditions, and environmental disasters. While prior research has focused on the challenges faced by refugees in finding work, prior research has neglected the organisational perspective. Therefore, our research question is: Which HR and management practices are viewed by refugees and organisational leaders as being most effective for the workplace integration of refugee employees? To address this research question, we conducted an exploratory semi‐structured interview study, drawing on quality of work life research. We conducted 37 semi‐structured interviews with refugees and people seeking asylum, as well as 35 interviews with managers who supervise refugees (including managers who develop employment programs and provide employment assistance for refugees). Based on the interview findings, we identify best HR practices and management strategies for integrating refugee employees in the workplace. Our interview findings and best HR practices for integrating refugee employees are summarised through the following five overall themes, each with additional sub‐dimensions: (1) workforce planning, (2) training and development, (3) inclusive work practices, (4) meaningful work, and (5) well‐being‐focused management. Our interview findings have important practical implications for organisations, managers, and policymakers who are working to advance the integration of refugees and people seeking asylum in the workforce.

A retrospective study of clinical outcomes for patients with esophageal cancer who were treated with radiotherapy alone

Introduction: Patients with esophageal cancer who are in a poor general condition receive radiotherapy alone, but outcomes are often unsatisfactory. The aim of this study was to clarify recent outcomes of radiotherapy alone for esophageal cancer. Methods: Patients who underwent 50 Gy or more of radiotherapy without chemotherapy were retrospectively reviewed. Endpoints were overall survival (OS), disease-specific survival (DSS), local control (LC), and progression-free survival (PFS). Survival curves were drawn using the Kaplan-Meier method and predictors were analyzed using the Cox proportional hazards model. Results: Sixty-nine patients were included. The median follow-up period was 17.9 months. The 5-year OS, DSS, LC, and PFS rates were 33.2%, 49.8%, 46.2%, and 16.8%, respectively. In the multivariate Cox proportional hazard model, clinical stage was a significant predictor for OS (hazard ratio [HR]: 4.42, 95% confidence interval [CI]: 1.80 – 11.17, p = 0.001), DSS (HR: 2.08, 95% CI: 1.43 – 3.12, p = 0.0001), LC (HR: 1.86, 95% CI: 1.28 – 2.74, p = 0.001), and PFS (HR: 1.65, 95% CI: 1.25 – 2.18, p = 0.0004). Radiation dose was a significant predictor for LC (HR: 0.87, 95% CI: 0.78 – 0.97, p = 0.018) and tumor location was a significant predictor for PFS (HR: 1.55, 95% CI: 1.10 – 2.19, p = 0.018). In subgroup analysis, the 5-year OS, DSS, LC, and PFS rates for stage I were 60.0%, 80.0%, 71.9%, and 46.1%, respectively. Conclusions: Stage, radiation dose and tumor location are significant predictors for outcomes. Patients with stage I esophageal cancer can be cured by radiotherapy alone.

A lightweight network model designed for alligator gar detection

When using advanced detection algorithms to monitor alligator gar in real-time in wild waters, the efficiency of existing detection algorithms is subject to certain limitations due to turbid water quality, poor underwater lighting conditions, and obstruction by other objects. In order to solve this problem, we developed a lightweight real-time detection network model called ARD-Net, from the perspective of reducing the amount of calculation and obtaining more feature map patterns. We introduced a cross-domain grid matching strategy to accelerate network convergence, and combined the involution operator and dual-channel attention mechanism to build a more lightweight feature extractor and multi-scale detection reasoning network module to enhance the network’s response to different semantics. Compared with the yoloV5 baseline model, our method performs equivalently in terms of detection accuracy, but the model is smaller, the detection speed is increased by 1.48 times, When compared with the latest State-of-the-Art (SOTA) method, YOLOv8, our method demonstrates clear advantages in both detection efficiency and model size,and has good real-time performance. Additionally, we created a dataset of alligator gar images for training.

Essentiality of dietary cholesterol and its interactions with phospholipid in juvenile slipper lobster (Thenus australiensis)

This study was conducted to verify the essentiality of dietary cholesterol for early juvenile slipper lobster, Thenus australiensis (initial weight 4.50 ± 0.72 g, mean ± SD, CV = 0.16), and to explore the potential for interactions between dietary cholesterol and phospholipid. An 8-week experiment was conducted using six experimental feeds containing three supplemental cholesterol concentrations (0, 0.2 and 0.4% dry matter) at two supplemental phospholipid concentrations (0% and 1.0% dry matter). Dietary cholesterol concentrations of ≥ 0.2% resulted in up to threefold greater weight gain compared to 0% dietary cholesterol, but without any significant main or interactive dietary phospholipid effect. An interaction was observed for lobster survival with lowest survival (46%) recorded for combined 0% cholesterol and 0% phospholipid compared to every other treatment (71–100%). However, all surviving lobsters at 0% dietary cholesterol, regardless of dietary phospholipid level, were in poor nutritional condition. Apparent feed intake (AFI) was significantly higher at dietary cholesterol ≥ 0.2% but was lower for each corresponding dietary cholesterol level at 1% dietary phospholipid. This implied that the feed conversion ratio was improved with supplemental phospholipid. In conclusion, this study confirms the essential nature of dietary cholesterol and that dietary phospholipid can provide additional benefits.