The first and second derivatives of a curve provide us fundamental
 information in the study of the behavior of curve near a point. However,
 if a curve is a polynomial space curve of degree n, we don’t know what
 is the geometric meaning of the n-th derivative of the curve? There is no
 doubt that the Frenet frame is not suitable for this purpose because it is
 constructed by using first and second derivatives of a curve. On the other
 hand, in this paper by using a new frame called as Flc-frame we are able
 to give the geometric meaning of the n-th derivative of a curve. Moreover,
 we explore some basic concepts regarding polynomial space curves from
 point of view of Flc-frame in three dimensional Euclidean space.